CN111024691A - Granules for absorbing animal urine and preparation method and application thereof - Google Patents
Granules for absorbing animal urine and preparation method and application thereof Download PDFInfo
- Publication number
- CN111024691A CN111024691A CN201911386313.4A CN201911386313A CN111024691A CN 111024691 A CN111024691 A CN 111024691A CN 201911386313 A CN201911386313 A CN 201911386313A CN 111024691 A CN111024691 A CN 111024691A
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- absorbing
- water
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
- G01N21/80—Indicating pH value
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
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- Health & Medical Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
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- Biotechnology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
A particle for absorbing urine from an animal comprising a pH indicator and a water-absorbing particle, wherein the pH indicator is capable of developing a color on the water-absorbing particle. The present application also discloses a method for preparing a particle for absorbing animal urine, the method comprising the steps of: adding 0.03-0.7% of acid-base indicator into the ethanol water solution to prepare indicator solution; uniformly mixing the prepared indicator solution with the water-absorbing particles; and (4) fully absorbing the indicator solution by the water-absorbing particles, and then air-drying to obtain the product. The particle for absorbing the animal urine contains the components capable of displaying pH, so that the pH value of the animal urine can be sensitively and intuitively indicated, and the health condition of the animal is preliminarily judged according to the detection result of the pH value.
Description
Technical Field
The application relates to the field of medical detection, in particular to particles for absorbing animal urine and a preparation method and application thereof.
Background
The pH of animal urine can reflect many potential diseases. Clinically, the initial diagnosis of the disease condition is usually made by using the data of animal urine. However, there are the following problems: 1) the point and time of urination by the animal is unknown, and it is difficult to require the animal to urinate in an unfamiliar location; 2) the pH of the animal urine is detected by using an instrument, so that the detection is not only troublesome, but also high in cost; 3) the use of pH paper for urine measurement requires waiting for fresh urine data, and if the urine is exposed to air for a long time, the pH of the urine will change. Based on the above problems, a product which is convenient to collect, high in sensitivity and low in cost is urgently needed.
Disclosure of Invention
In order to achieve the above object, according to one aspect of the present application, there is provided a particle for absorbing urine of an animal, the particle comprising a pH indicator and a water-absorbing particle, the pH indicator being capable of developing a color on the water-absorbing particle.
The pH color reaction is a reaction with reduced entropy, so that the reaction result is not easily interfered by the external environment.
Preferably, the pH indicator is selected from at least one of an acidic indicator and a basic indicator.
Preferably, the pH indicator is selected from at least one of methyl red, bromocresol green and bromothymol blue.
The indicators are not limited to methyl red, bromocresol green and bromothymol blue, any substance which changes color according to pH change can be used as the indicator, and the three indicators provided by the invention are common indicators which are more accurate and sensitive.
Preferably, the pH indicator is a mixture of methyl red, bromocresol green and bromothymol blue, wherein the weight ratio of methyl red, bromocresol green and bromothymol blue is (3-50): (0.5-20): (1-20).
Preferably, the water-absorbing particles are transparent or white particles having water absorption property, and preferably, the water-absorbing particles are at least one selected from silica gel and water-absorbing resin.
Another aspect of the present invention relates to a method for preparing said particles for absorbing animal urine, characterized in that it comprises the following steps:
adding 0.03-0.7% of acid-base indicator into the ethanol water solution to prepare indicator solution;
uniformly mixing the prepared indicator solution with the water-absorbing particles;
the mixing is carried out by adding indicator solution into the water-absorbing particles until the particles are submerged.
And (4) fully absorbing the indicator solution by the water-absorbing particles, and then air-drying to obtain the product.
Preferably, the ethanol concentration of the ethanol aqueous solution is 50-80%.
Another aspect of the invention relates to a litter comprising the particles for absorbing animal urine according to any one of claims 1-5.
Preferably, the cat litter also comprises other water-absorbing materials, wherein the other water-absorbing materials comprise silica gel, water-absorbing resin, wood chips, bentonite, paper and porous fiber.
The particles of the present invention may be used in combination with other urine absorbents, common absorbents including, but not limited to, wood chips, kaolin, paper, porous fibers, and the like, and may be reused.
The particle for absorbing the animal urine contains the components capable of displaying pH, so that the pH value of the animal urine can be sensitively and intuitively indicated, and the health condition of the animal is preliminarily judged according to the detection result of the pH value. The particle for absorbing animal urine has simple and clear process, and the produced particle can be mixed with other carriers to obtain products suitable for various animals and even human beings.
Detailed Description
In order to make the technical solutions better understood by those skilled in the art, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only partial embodiments of the present application, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to the embodiments with reference to the attached drawings.
Example 1
Granules for absorbing animal urine were prepared according to the following procedure:
1. adding 0.03% methyl red, 0.2% bromocresol and 0.01% bromothymol into 50% ethanol water solution, mixing uniformly, and preparing into indicator solution;
2. adding the prepared indicator solution into the water-absorbing particles until the particles are submerged, and uniformly mixing;
3. and (4) fully absorbing the indicator solution by the water-absorbing particles, and then air-drying to obtain the product.
Example 2
Granules for absorbing animal urine were prepared according to the following procedure:
1. adding 0.5% methyl red, 0.005% bromocresol and 0.02% bromothymol into 50% ethanol water solution, mixing uniformly, and preparing into indicator solution;
2. adding the prepared indicator solution into the water-absorbing particles until the particles are submerged, and uniformly mixing;
3. and (4) fully absorbing the indicator solution by the water-absorbing particles, and then air-drying to obtain the product.
Example 3
Granules for absorbing animal urine were prepared according to the following procedure:
1. adding 0.2% methyl red, 0.1% bromocresol and 0.15% bromothymol into 50% ethanol water solution, mixing uniformly, and preparing into indicator solution;
2. adding the prepared indicator solution into the water-absorbing particles until the particles are submerged, and uniformly mixing;
3. and (4) fully absorbing the indicator solution by the water-absorbing particles, and then air-drying to obtain the product.
Experiment of detection accuracy
Urine from 20 cats with confirmed diagnosis of calcium oxalate calculi (typical diagnosis of cats with calcium oxalate calculi is that urine is acidic, and urine pH is usually less than 6) was dropped into the pellets prepared in examples 1-3. The discoloration was counted and the results are shown in the following table:
according to statistics, only one example of urine dropped into the particles, the particles turned yellow and not orange-red, and the particles in other experiments all turned orange-red. Therefore, it can be considered that the coincidence of the particle detection result for absorbing urine and the data of the sample of the present application is high.
The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims (9)
1. A particle for absorbing animal urine, comprising a pH indicator and a water-absorbing particle, wherein the pH indicator is capable of developing a color on the water-absorbing particle.
2. The particle for absorbing animal urine according to claim 1, wherein the pH indicator is at least one selected from the group consisting of an acidic indicator and a basic indicator.
3. The particle for absorbing animal urine according to claim 1 wherein the pH indicator is selected from at least one of methyl red, bromocresol green and bromothymol blue.
4. The particle for absorbing animal urine according to claim 1 wherein the pH indicator is a mixture of methyl red, bromocresol green and bromothymol blue, wherein the weight ratio of methyl red, bromocresol green and bromothymol blue is (3-50): (0.5-20): (1-20).
5. Particles for absorbing animal urine according to claim 1, wherein the water absorbing particles are transparent or white particles having water absorbing property, preferably, the water absorbing particles are at least one selected from silica gel and water absorbing resin.
6. Process for the preparation of a granulate according to any one of claims 1 to 5 for absorbing animal urine, characterized in that it comprises the following steps:
adding 0.03-0.7% of acid-base indicator into the ethanol water solution to prepare indicator solution;
uniformly mixing the prepared indicator solution with the water-absorbing particles;
and (4) fully absorbing the indicator solution by the water-absorbing particles, and then air-drying to obtain the product.
7. The method according to claim 6, wherein the ethanol concentration of the aqueous ethanol solution is 50-80%.
8. A litter comprising particles according to any one of claims 1 to 5 for absorbing animal urine.
9. The litter of claim 8 further comprising other water-absorbing materials, said other water-absorbing materials comprising silica gel, water-absorbing resin, wood chips, bentonite, paper, porous fiber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911386313.4A CN111024691A (en) | 2019-12-26 | 2019-12-26 | Granules for absorbing animal urine and preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911386313.4A CN111024691A (en) | 2019-12-26 | 2019-12-26 | Granules for absorbing animal urine and preparation method and application thereof |
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| Publication Number | Publication Date |
|---|---|
| CN111024691A true CN111024691A (en) | 2020-04-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201911386313.4A Pending CN111024691A (en) | 2019-12-26 | 2019-12-26 | Granules for absorbing animal urine and preparation method and application thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024186286A1 (en) * | 2023-03-08 | 2024-09-12 | Albayrak Serhat | Clay-containing cat litter with health indicator and preparation method |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998043654A1 (en) * | 1997-03-31 | 1998-10-08 | Inkine Pharmaceutical Company, Inc. | Non-aqueous colonic purgative formulations |
| CN101140278A (en) * | 2007-11-05 | 2008-03-12 | 刘世安 | Animals urine checking method, detecting and preparation method |
| CN101672799A (en) * | 2009-10-13 | 2010-03-17 | 青岛美高集团有限公司 | Cat urine pH indicating material, pH indicating silica gel cat sand and preparation method thereof |
| CN110583496A (en) * | 2019-09-06 | 2019-12-20 | 孙雨强 | Cat urine pH indicating material, pH indicating cat litter and preparation method thereof |
-
2019
- 2019-12-26 CN CN201911386313.4A patent/CN111024691A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998043654A1 (en) * | 1997-03-31 | 1998-10-08 | Inkine Pharmaceutical Company, Inc. | Non-aqueous colonic purgative formulations |
| CN101140278A (en) * | 2007-11-05 | 2008-03-12 | 刘世安 | Animals urine checking method, detecting and preparation method |
| CN101672799A (en) * | 2009-10-13 | 2010-03-17 | 青岛美高集团有限公司 | Cat urine pH indicating material, pH indicating silica gel cat sand and preparation method thereof |
| CN110583496A (en) * | 2019-09-06 | 2019-12-20 | 孙雨强 | Cat urine pH indicating material, pH indicating cat litter and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024186286A1 (en) * | 2023-03-08 | 2024-09-12 | Albayrak Serhat | Clay-containing cat litter with health indicator and preparation method |
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Application publication date: 20200417 |