WO2014054389A8 - 表面プラズモンを利用した免疫測定方法 - Google Patents

表面プラズモンを利用した免疫測定方法 Download PDF

Info

Publication number
WO2014054389A8
WO2014054389A8 PCT/JP2013/074399 JP2013074399W WO2014054389A8 WO 2014054389 A8 WO2014054389 A8 WO 2014054389A8 JP 2013074399 W JP2013074399 W JP 2013074399W WO 2014054389 A8 WO2014054389 A8 WO 2014054389A8
Authority
WO
WIPO (PCT)
Prior art keywords
surface plasmon
absorbance
spfs
spr
whole blood
Prior art date
Application number
PCT/JP2013/074399
Other languages
English (en)
French (fr)
Other versions
WO2014054389A1 (ja
Inventor
真紀子 大谷
高敏 彼谷
Original Assignee
コニカミノルタ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by コニカミノルタ株式会社 filed Critical コニカミノルタ株式会社
Priority to EP13843487.3A priority Critical patent/EP2905617B1/en
Priority to JP2014539652A priority patent/JP6341089B2/ja
Priority to US14/433,230 priority patent/US10228326B2/en
Publication of WO2014054389A1 publication Critical patent/WO2014054389A1/ja
Publication of WO2014054389A8 publication Critical patent/WO2014054389A8/ja

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

　本発明は、全血測定を可能とし、全血処理時の測定値のばらつきが少なく、極めて正確な測定結果を得ることができるとともに、全血、血清、及び血漿を同じ装置内で測定することができるＳＰＲ又はＳＰＦＳ免疫測定方法を提供することを課題とする。　本発明は、ＳＰＲ（表面プラズモン共鳴法）又はＳＰＦＳ（表面プラズモン励起増強蛍光分光法）を利用する免疫測定方法であって、試料の吸光度を測定する吸光度測定工程と、該吸光度測定工程で測定した吸光度の結果に対応したモードを設定するモード設定工程と、該モード設定工程で設定したモードに応じて処理条件が設定された一または複数の工程と、を含むＳＰＲ又はＳＰＦＳ免疫測定方法により、上記課題を解決する。
PCT/JP2013/074399 2012-10-03 2013-09-10 表面プラズモンを利用した免疫測定方法 WO2014054389A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP13843487.3A EP2905617B1 (en) 2012-10-03 2013-09-10 Immunoassay method and system utilizing surface plasmons
JP2014539652A JP6341089B2 (ja) 2012-10-03 2013-09-10 表面プラズモンを利用した免疫測定方法
US14/433,230 US10228326B2 (en) 2012-10-03 2013-09-10 Immunoassay method utilizing surface plasmon

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012-221362 2012-10-03
JP2012221362 2012-10-03

Publications (2)

Publication Number Publication Date
WO2014054389A1 WO2014054389A1 (ja) 2014-04-10
WO2014054389A8 true WO2014054389A8 (ja) 2015-03-26

Family

ID=50434720

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2013/074399 WO2014054389A1 (ja) 2012-10-03 2013-09-10 表面プラズモンを利用した免疫測定方法

Country Status (4)

Country Link
US (1) US10228326B2 (ja)
EP (1) EP2905617B1 (ja)
JP (1) JP6341089B2 (ja)
WO (1) WO2014054389A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2910947B1 (en) * 2012-10-18 2019-02-13 Konica Minolta, Inc. Assay method using surface plasmon-field enhanced fluorescence spectroscopy
EP3273226A4 (en) 2015-03-17 2018-01-31 Konica Minolta, Inc. Detection device
CN105758826A (zh) * 2015-12-29 2016-07-13 中国政法大学 一种基于Labview控制SPR数据采集分析方法
EP3514522A4 (en) * 2016-09-14 2019-11-06 Konica Minolta, Inc. MEASURING METHOD
CN110865104B (zh) * 2019-11-28 2022-06-24 北京乐普诊断科技股份有限公司 一种血液样本类型识别检测系统

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5987346A (en) * 1993-02-26 1999-11-16 Benaron; David A. Device and method for classification of tissue
JPH1123575A (ja) 1997-06-30 1999-01-29 Dainippon Printing Co Ltd 心筋梗塞マーカーを測定する方法
JPH11242031A (ja) * 1998-02-26 1999-09-07 Dainippon Printing Co Ltd Ｏ−１５７検出用測定チップ
US6514770B1 (en) * 1999-07-30 2003-02-04 Mitsubishi Chemical Corporation Immunoassay
JP3778248B2 (ja) * 1999-07-30 2006-05-24 独立行政法人科学技術振興機構 偏光を用いたｓｐｒ装置及びｓｐｒ測定方法
US20040023293A1 (en) * 1999-09-27 2004-02-05 Kreimer David I. Biochips for characterizing biological processes
JP4547110B2 (ja) 2000-07-27 2010-09-22 シスメックス株式会社 全血免疫測定方法
JP3779885B2 (ja) 2001-03-26 2006-05-31 株式会社堀場製作所 免疫測定方法
JP4420335B2 (ja) * 2004-09-10 2010-02-24 エヌ・ティ・ティ・アドバンステクノロジ株式会社 表面プラズモン測定装置および測定方法
US20090093968A1 (en) * 2005-07-14 2009-04-09 Ryoko Kawamata Analysis device and analysis method
JP2007040746A (ja) * 2005-08-01 2007-02-15 Fujifilm Corp 全反射減衰を利用した分析における反応速度係数の測定方法
WO2009019619A1 (en) 2007-08-09 2009-02-12 Koninklijke Philips Electronics N. V. Microelectronic sensor device for optical examinations in a sample medium
US20090097022A1 (en) * 2007-08-24 2009-04-16 Dynamic Throughput Inc. Discovery tool with integrated microfluidic biomarker optical detection array device and methods for use
WO2009087519A2 (en) * 2008-01-03 2009-07-16 Koninklijke Philips Electronics N. V. Wetting detection and removal
JP5445348B2 (ja) * 2010-06-23 2014-03-19 株式会社島津製作所 蛍光分光光度計

Also Published As

Publication number Publication date
WO2014054389A1 (ja) 2014-04-10
JP6341089B2 (ja) 2018-06-13
US10228326B2 (en) 2019-03-12
EP2905617A4 (en) 2016-08-10
US20150260654A1 (en) 2015-09-17
JPWO2014054389A1 (ja) 2016-08-25
EP2905617B1 (en) 2019-03-20
EP2905617A1 (en) 2015-08-12

Similar Documents

Publication Publication Date Title
WO2014054389A8 (ja) 表面プラズモンを利用した免疫測定方法
EP2660584A3 (en) Method and apparatus for quantifying solutions comprised of multiple analytes
EP3350579A4 (en) MEASURING THE CONCENTRATION OF ANALYTES IN LIQUID SAMPLES BY SURFACE-EXPERIENCED RAMAN SPECTROSCOPY
IN2014KN01168A (ja)
NZ596659A (en) Bulbless spectrometer
WO2008123866A3 (en) Gene expression profiling for identification, monitoring and treatment of ovarian cancer
MX2013009208A (es) Metodo y aparato para utilizar multiples envolventes espectroscopicas para determinar componentes con mayor precision y rango dinamico.
WO2011061944A8 (ja) 蛍光免疫測定方法
MX2016006125A (es) Procedimiento, matriz y uso de los mismos.
WO2012075256A3 (en) Sample metering device and assay device with integrated sample dilution
IN2014KN02807A (ja)
MX2019011119A (es) Metodos espectroscopicos para detectar y caracterizar microorganismos.
WO2010126272A3 (ko) Fret 바이오센서를 이용한 리간드의 검출방법
WO2017194613A3 (en) Method, array and use thereof
WO2015185488A3 (en) Method and apparatus for froth flotation process using optical measurements
MX2019005697A (es) Medicion de longitud de onda secuencial multiple de una muestra liquida.
EP2671044A1 (de) Verfahren und vorrichtung zur bestimmung optischer eigenschaften durch gleichzeitiges messen von intensitäten an dünnen schichten mit licht von mehreren wellenlängen
BRPI0906419A2 (pt) Reativos para detecção de produto de análise, tira de sensor eletroquímico, método de produção de tira de sensor eletroquímico e medidor para uso em combinação com tira de teste.
WO2014144725A3 (en) Melatonin monoclonal antibody, detection, methods and uses thereof
WO2008008878A3 (en) Method for deriving consistent color measurements
WO2016090244A3 (en) Methods and devices for performing high dynamic range immunoassays
WO2015189591A3 (en) Method and arrays for use in diagnosing early breast cancer
MX2013006156A (es) Analisis espectral del infrarrojo medio de un material heterogeneo que fluye.
WO2011145895A3 (ko) 반사식 흡광도 측정 장치 및 이를 포함하는 반사식 흡광도 및 측방유동 분석 일체형 장치
CN104048922A (zh) 一种荧光光谱偏振度和偏振角的测量方法

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 13843487

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2013843487

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2014539652

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 14433230

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE