WO2013180417A1 - Nouvelle membrane à base de nanofibres et son procédé de préparation - Google Patents

Nouvelle membrane à base de nanofibres et son procédé de préparation Download PDF

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Publication number
WO2013180417A1
WO2013180417A1 PCT/KR2013/004385 KR2013004385W WO2013180417A1 WO 2013180417 A1 WO2013180417 A1 WO 2013180417A1 KR 2013004385 W KR2013004385 W KR 2013004385W WO 2013180417 A1 WO2013180417 A1 WO 2013180417A1
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WO
WIPO (PCT)
Prior art keywords
nanofiber membrane
membrane
animal cartilage
cartilage powder
pva
Prior art date
Application number
PCT/KR2013/004385
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English (en)
Korean (ko)
Inventor
윤정호
민병현
윤준진
신수정
맹유정
Original Assignee
리젠프라임 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 리젠프라임 주식회사 filed Critical 리젠프라임 주식회사
Publication of WO2013180417A1 publication Critical patent/WO2013180417A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne un procédé de préparation d'une membrane à base de nanofibres, comprenant les étapes suivantes : modification d'une poudre de cartilage d'animal produite au moyen d'un tissu de cartilage d'animal ; et production d'une membrane à base de nanofibres au moyen d'un procédé de filage électrostatique, après mélange de la poudre de cartilage d'animal modifiée et d'un alcool polyvinylique (PVAL), qui est un polymère de synthèse, à un taux approprié. Étant donné que la présente invention peut modifier la poudre de cartilage d'animal pour obtenir un matériau qui se dissout facilement dans une solution aqueuse neutre, telle qu'un milieu de culture ou une solution PBS, la présente invention est adéquate pour la préparation d'un article sous la forme d'un hydrogel ou d'un film ne pouvant pas être produit au moyen de la poudre de cartilage d'animal existante.
PCT/KR2013/004385 2012-05-31 2013-05-20 Nouvelle membrane à base de nanofibres et son procédé de préparation WO2013180417A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2012-0057965 2012-05-31
KR1020120057965A KR20130134447A (ko) 2012-05-31 2012-05-31 신규한 나노섬유막 및 이의 제조방법

Publications (1)

Publication Number Publication Date
WO2013180417A1 true WO2013180417A1 (fr) 2013-12-05

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ID=49673561

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2013/004385 WO2013180417A1 (fr) 2012-05-31 2013-05-20 Nouvelle membrane à base de nanofibres et son procédé de préparation

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KR (1) KR20130134447A (fr)
WO (1) WO2013180417A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101772316B1 (ko) * 2016-03-11 2017-08-29 아주대학교산학협력단 생체 내 분해속도 및 물성 조절 가능한 생체적합성 돼지연골 유래 세포외기질 막 제조방법 및 상기 돼지연골 유래 세포외기질을 유효성분으로 함유하는 유착방지용 조성물
KR101997966B1 (ko) * 2016-06-30 2019-07-09 아주대학교산학협력단 생분해기간 조절이 가능한 생체적합성 연골유래조직 시트
KR101866359B1 (ko) 2016-08-30 2018-06-12 아주대학교산학협력단 동물 연골 유래 조직을 이용한 가교된 나노섬유 시트 및 이의 제조방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0927053B1 (fr) * 1996-08-27 2003-04-02 Fusion Medical Technologies, Inc. Hydrogels polymeres fragmentes empechant l'adhesion et leur preparation
WO2007104322A1 (fr) * 2006-03-13 2007-09-20 Naturin Gmbh & Co Poudre de collagène et composition thermoplastique à base de collagène servant à préparer des articles conformés
WO2008093341A2 (fr) * 2007-01-31 2008-08-07 Technion Research & Development Foundation Ltd. Échafaudages électrofilés et leurs procédés de génération et d'utilisation
KR20100041027A (ko) * 2008-10-13 2010-04-22 아주대학교산학협력단 동물조직 분말을 이용한 다공성 3차원 지지체의 제조방법 및 이를 이용하여 제조된 다공성 3차원 지지체

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0927053B1 (fr) * 1996-08-27 2003-04-02 Fusion Medical Technologies, Inc. Hydrogels polymeres fragmentes empechant l'adhesion et leur preparation
WO2007104322A1 (fr) * 2006-03-13 2007-09-20 Naturin Gmbh & Co Poudre de collagène et composition thermoplastique à base de collagène servant à préparer des articles conformés
WO2008093341A2 (fr) * 2007-01-31 2008-08-07 Technion Research & Development Foundation Ltd. Échafaudages électrofilés et leurs procédés de génération et d'utilisation
KR20100041027A (ko) * 2008-10-13 2010-04-22 아주대학교산학협력단 동물조직 분말을 이용한 다공성 3차원 지지체의 제조방법 및 이를 이용하여 제조된 다공성 3차원 지지체

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JANNESARI ET AL.: "Composite poly(vinyl alcohol)/poly(vinyl acetate) electrospun nanofibrous mats as a novel wound dressing matrix for controlled release of drugs", INTERNATIONAL JOURNAL OF NANOMEDICINE, vol. 6, 19 May 2011 (2011-05-19), pages 993 - 1003 *

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KR20130134447A (ko) 2013-12-10

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