WO2013174691A1 - Dispositif et procédé d'examen thermique du sein féminin - Google Patents

Dispositif et procédé d'examen thermique du sein féminin Download PDF

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Publication number
WO2013174691A1
WO2013174691A1 PCT/EP2013/060026 EP2013060026W WO2013174691A1 WO 2013174691 A1 WO2013174691 A1 WO 2013174691A1 EP 2013060026 W EP2013060026 W EP 2013060026W WO 2013174691 A1 WO2013174691 A1 WO 2013174691A1
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WO
WIPO (PCT)
Prior art keywords
breast
cooling
plates
thermal sensor
temperature
Prior art date
Application number
PCT/EP2013/060026
Other languages
German (de)
English (en)
Inventor
Heinrich M. WEHBERG
Original Assignee
Konrad Wehberg Medizintechnik
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Filing date
Publication date
Application filed by Konrad Wehberg Medizintechnik filed Critical Konrad Wehberg Medizintechnik
Publication of WO2013174691A1 publication Critical patent/WO2013174691A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
    • G01K11/00—Measuring temperature based upon physical or chemical changes not covered by groups G01K3/00, G01K5/00, G01K7/00 or G01K9/00
    • G01K11/12—Measuring temperature based upon physical or chemical changes not covered by groups G01K3/00, G01K5/00, G01K7/00 or G01K9/00 using changes in colour, translucency or reflectance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0041—Detection of breast cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A61B5/015—By temperature mapping of body part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312—Breast evaluation or disorder diagnosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
    • G01K13/00—Thermometers specially adapted for specific purposes
    • G01K13/20—Clinical contact thermometers for use with humans or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0271—Thermal or temperature sensors
    • A61B2562/0276—Thermal or temperature sensors comprising a thermosensitive compound
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
    • G01K2213/00—Temperature mapping

Definitions

  • the present invention relates to a device and a method for the thermal examination of the female breast.
  • mammography i. an X-ray method, used as the "gold standard.” This method is associated with a, albeit low, radiation exposure for the patient
  • Mammacarcinomas can be diagnosed.
  • thermography the heat development during the earliest beginnings of a carcinoma development already in the preliminary stages, z.
  • LCIS and DCIS In hyperplastic dysplasia, LCIS and DCIS.
  • Very sensitive high-resolution sensors reproduce an image of the measured radiation of the heat-emitting body during IR thermography.
  • Liquid crystal thermography or ELC thermography can be achieved by contact of the ELC film with the body region to be examined
  • Heat emission can be detected and documented in fractions of a second.
  • conduction, heat conduction or heat flow the heat flows from the place of formation according to the second law of thermodynamics
  • thermography gives priority to a functional, less an anatomical information.
  • thermography in the context of breast cancer diagnostics, it basically represents a useful supplement to the routine procedures of mammography and ultrasound, which provide only structural information.
  • Plate thermography or ELC thermography or contact thermography has traditionally been a technique in which the properties of liquid cholesterol crystals are used to reflect light of different wavelengths depending on the temperature. These liquid crystals are embedded in a rigid or elastic display, which is placed on the body part to be examined. The resulting color image after a short time is qualitatively evaluated by the examiner and possibly photographically documented.
  • Cholesterol crystals is displayed on a display a specific temperature range (temperature window), in which the color of the reflected light corresponds to a certain temperature. This allows a semiquantitative evaluation of the temperature image.
  • WO 79/00594 and US Pat. No. 3,970,074 disclose devices in which the breast is pressed against a plate equipped with temperature sensors in a matrix-like manner and the skin temperature is measured. The measured data are processed electronically, whereby certain temperature distributions on the skin are an indication for a mammary carcinoma.
  • US 4,005,166 discloses a brassiere that includes a single
  • Temperature sensors is equipped. This will constantly check the skin temperature at the appropriate points. Certain changes in the skin temperature indicate the development of mammary carcinoma.
  • thermography A second group of thermography methods forms the so - called plate thermography.
  • a corresponding device is disclosed in DE 83 26 341 U 1.
  • a thermographic plate is pressed against the female breast.
  • a liquid crystal coating of the plate changes depending on the temperature
  • WO 85/00508 discloses a device for receiving a
  • thermo-optic image of the female breast with a housing having on its side facing the female breast a frame, a
  • thermo-optical film which can be fastened to the frame, an illumination device arranged in the housing for illuminating the thermo-optical film and a digital camera arranged in the housing relative to the frame.
  • WO 00/064332 discloses a device for receiving a
  • thermo-optical film which can be fastened to the frame, a arranged on the side facing away from the breast of the frame, transparent cooling box with a disposed on its side facing away from the breast side of the frame anti-reflection disk having a cooling medium inlet and a cooling medium drain u nd in his
  • Initial position is not in contact with the film, one with respect to the temperature of a cooling medium adjustable thermostat, which is connected to form a cooling circuit via hose lines with the cooling medium inlet and outlet, an arranged in the housing lighting device for illuminating the thermo-optic film, one in the Housing relative to the frame arranged digital camera, a clamping device for clamping the breast between two surfaces, wherein one of the surfaces is formed by the film, a contact making device for establishing a surface contact between a film side facing the cooling box and the side facing away from the breast side of the film , a time measuring device for measuring the
  • the clamping device comprises a housing connected to the housing, extending parallel to the frame cushion whose distance from the frame is variable.
  • the pad is in this case connected via a bracket arranged at a right angle to the housing.
  • the square frame is held at its four corners by means of pins on the housing with springs concentrically extending to the pins in such a way that the attached to the frame thermo-optical film in unloaded
  • Condition of the springs is located at a distance from the cooling box.
  • An existing locking device is used to lock the frame in making a contact between the thermo-optic film and the
  • a prolonged cooling time due to the skin duplication until a black discoloration of the foil is achieved leads to a prolonged cooling time for the skin portions lying above the glandular body, which in turn impairs the sensitivity.
  • thermo-optical image in the process is too fast, so that the relevant particularly warm areas of the breast is not As you might expect, the reconstruction of the thermo-optic image in such a case can not be captured in one sequence, instead the image becomes one with all
  • this object is achieved by a device for thermal examination of the female breast
  • thermo sensor plates are aligned with each other so that the breast is clamped between the two thermal sensor plates.
  • the object is also achieved by a method for thermo-optic diagnosis of the female breast with the steps
  • the sensitivity of the examination can thus be significantly increased over a simple frontal application of a thermo-optical plate to the breast, because it is ensured that all areas of the breast are brought into contact with the thermosensor plates as far as the axial-axial extension.
  • the thermal sensor plates by appropriate alignment of the thermal sensor plates, the breast wall near portions of the signaling skin can be detected.
  • cooling plates which are respectively associated with the first and the second thermal sensor plate.
  • a controlled pressure can be exerted on the breast and thus a certain compression of the breast can be achieved.
  • the glandular body of older women consists to a greater extent of fatty tissue and is therefore softer and more easily compressible. Adipose tissue-rich glandular tissue conducts the heat worse than the glandular tissue of a younger patient. For this reason, slight compression of the glandular tissue of elderly women is of particular advantage because it shortens the routes of heat conduction from the lesion to the signal-giving skin.
  • the evaluation unit calculates more than just a two-dimensional distribution of the heat sources for evaluating the measured temperatures. So z. B. from a higher measured temperature at one of the two
  • thermosensorplatten be concluded that a heat source is closer to this thermosensor plate than the other thermosensor plate.
  • the thermal sensor plates have flat surfaces.
  • the thermal sensor plates may be thermo-optical films which change their color as a function of the temperature, the color change being detected by one or two cameras.
  • the cooling plates can thereby cool the breast through the thermoforming films.
  • the cooling plates are included Advantageously enough, behind the thermal films arranged and transparent (with transparent cooling medium), so that cameras through the cooling plates can take a picture of the thermo-films. If necessary, it should be noted that the cooling medium guided through the cooling plates does not form bubbles and does not contain any impurities, otherwise the
  • the thermal films are preferably taut on a frame, so that there is a barely compliant arrangement, which is suitable to pinch the breast between two thermal films.
  • the thermal film can be clamped so tightly that a yielding results by at most two mm.
  • thermosensor plate may also be a matrix of small thermosensors that directly determine the temperature.
  • O-calibration black detection
  • the cooling device for cooling the breast it may, for. B. by two
  • Cold plates act, which are flowed through by a cooling medium.
  • the cooling medium can be cooled or warmed up by a heat exchanger. Heat exchangers allow a faster adjustment of the temperature of the cooling circuit to a new required temperature, eg. B. when using another slides for another patient. It can be provided that the cooling plates are automatically applied when it has been determined after applying the thermal sensor plates that there is no significant change in temperature at the surface of the breast. Instead of a fully automatic application of the cooling plates can also be a signal
  • a standardized special automatic cooling can be used which evenly cools the uppermost layer of the skin at a temperature only a few degrees below chest temperature. This avoids reactive hyperemia.
  • Experimental investigations have shown that cooling by about 3 ° C to 5 ° C can be particularly advantageous.
  • the cooling plate can transmit the cold of the cooling medium to the chest through contact with the breast.
  • the evaluation unit for evaluating the measured temperatures can, for. B. be a computer that receives the signals from the
  • thermosensor plates are aligned with each other so that the breast is clamped between the two thermosensor plates, so as a whole as large as possible and tight contact surface between the chest and
  • the pinching of the breast according to the invention means a pressure on the breast, which leads to a deformation of the breast, but is not painful for the patient.
  • the examination of the patients with the device according to the invention can be delegated and can be performed by a helper.
  • the evaluation unit can also have a display that contains instructions for
  • test film is inserted into one of the two thermosensor plates, which are in the position for
  • Frontal recording is located.
  • the test film reacts as soon as the contact with the breast takes place z. B. within about 2 to 3 seconds.
  • On a display the color change of the foil is indicated in the form that the foil to be selected for the diagnostics is indicated by the range of the starting position of the colored change on the test foil. Cooling is not required for automatic slide selection.
  • the thermal sensor plates are aligned substantially parallel.
  • Substantially parallel should be parallel or at an angle of a few degrees, z. B. maximum 5 °, mean.
  • a substantially parallel orientation of the thermal sensor plates is technically particularly easy to implement.
  • it is particularly easy to estimate from the images recorded with the thermal sensor plate, a three-dimensional distribution of the heat sources when the thermal sensor plates are substantially parallel.
  • Thermosensorplatten are adjustable.
  • Adjustability of the distance and orientation of the thermal sensor plates allows adaptation to the shape and size of the patient's breast. This is of particular importance in order to achieve the largest possible contact surface between breast and thermosensor plates and at the same time to make the examination not too uncomfortable or even painful for the patient.
  • the distance of the thermal sensor plates can be adjusted and an angle of the thermal sensor plates to each other.
  • the thermal sensor plates can be tilted relative to one another in more than one plane.
  • the set distance or the angular position can be read or automatically detected by the evaluation unit. This ensures that the recording conditions are accurate
  • the position and orientation of the thermal sensor plates are adjusted automatically by a motor-driven device.
  • the method can be carried out particularly efficiently and the recording conditions are reproduced particularly accurately.
  • Thermal sensor plates and breast is too big. Thus, injuries can be prevented by incorrect adjustment of the thermal sensor plates.
  • Cooling device has a first and a second cooling plate, which are associated with the first and the second thermal sensor plate and are each movably mounted to these.
  • An arrangement of thermosensor plate and associated cooling plate is also referred to below as a thermo-arrangement.
  • the first cooling plate can be aligned parallel to the first thermal sensor plate and movably mounted at a distance therefrom.
  • the second thermal sensor plate can be designed accordingly.
  • the folding mechanism has proven to be powerful experimentally, but requires mechatronics but a relatively high load capacity and brings the disadvantage of higher space requirements for the housing of the thermal arrangement with it.
  • thermo-optic image it is important to avoid any deterioration of the picture quality during the recording of the reconstruction of the thermo-optic image.
  • Another way of avoiding visual loss of quality is, for example, a clear glass clearing the cooling glass which consists of an elastic thermally conductive material and has only the size of the extension of the beam path of the camera whose lens is located directly on the cooling plate located in the rest position.
  • the camera At the time of the black detection and in the time before that, ie during the cooling time, the camera is at a certain distance from the cooling plate. The task of the camera to detect the time of the black detection to trigger an automatic interruption of the cooling at this moment is not affected by a slight negligible for this quality degradation.
  • thermosensor plate If a thermal foil is used as the thermosensor plate, the view of the thermo foil can be released after the cooling process has ended by moving the cooling plate away for a camera. If the camera is located behind the cooling plate, it may be necessary to provide a small recess in the cooling plate for the camera.
  • the recess may be made with a transparent material, for. As glass or a transparent film.
  • cooling plates can be designed as a folding away or as a move away from the thermal sensor plate, such that the cooling plates remains parallel to the thermal sensor plate.
  • Cooling plates are supplied via hoses with a cooling medium.
  • thermosensor plates and their support can thus be designed to save space, while at another point, the possibly consuming or space-demanding cooling of the cooling medium takes place.
  • a 3D camera is additionally provided, in particular a combination of a camera and a sensor for structured light.
  • the 3D camera By the 3D camera, it is possible to perform a measurement of the shape of the breast or caused by the application of the thermal sensor plates deformation of the breast.
  • the thermal sensor plates By irradiating the chest with structured light and recording the reflected light with a conventional camera, it is thus possible without contact and quickly to precisely determine the contour of the breast in the areas in which it does not abut against the thermal sensor plates.
  • the position of the nipple can be detected accurately.
  • the 3D camera is designed to take a picture of the breast from the front.
  • the evaluation unit for evaluating the measured temperatures is adapted to a spatial distribution and a temporal evolution of the measured
  • the device can fully automatically make an estimate of the position of a heat source in the breast.
  • the heat source to be determined may be a lesion or blood vessels running to and around the lesion. The determination of the position of the heat source can be done much more accurately than if this is estimated by a doctor.
  • the location of the carcinoma formation is the cause of both thermal biosignals on the thermosensor plates. Therefore, the two signals occur at a certain time interval to each other when the physical process is not in the middle between the two thermal sensor plates.
  • the time offset can also have a flatter function curve.
  • the function curve profile is identical on both thermosensor plates. Assuming approximately constant heat conductivity in the breast, it is therefore possible to make statements about a non-central position of the heat source from different measured function curves.
  • the cooling time in both opposing thermal sensor plates may vary depending on the thermo-optic heat pattern per thermosensor plate, resulting in earlier or later black detection, thus ending the cooling time and thus earlier or later start of sequence imaging (e.g. 15 recording / sec in HD format). This can be taken into account accordingly by the evaluation method.
  • Thermosensor plate of the opposite side results, with to be considered.
  • Thermosensorplatten can z. B. be calculated by measuring for pixels on the left or right thermal sensor plate exceeding a certain threshold temperature. If this limit is measured on a pixel on the first plate 0.5 seconds earlier than on the second plate, z. B. in a method of the invention are determined from the fact that the heat source is approximately 1 cm closer to the first plate than on the second plate.
  • the pixel change applies analogously to the creation of a function curve. Further possibilities of algorithmic calculation result from the different distances of the isotherms, i. H. Regions with the same surface temperature, for the position of the heat source.
  • the device thus allows a fully automatic help for the diagnosis. For example, a rapid increase in temperature indicates a more perfused and potentially more dangerous lesion. Such a rapid rise in temperature can be determined more accurately and reliably by a camera with high temporal and spatial resolution and a corresponding evaluation unit than with manual analysis by the physician.
  • the heat distribution is recorded with a temporal resolution of at least ten images per second and a spatial resolution of at least 500 ⁇ 500 points, in particular at least 1280 ⁇ 720 points. It has been shown that a particularly accurate diagnosis is possible with a high spatial and temporal resolution. Such HD cameras are also available at low cost and can be read by a commercial computer.
  • Thermosensorplatten are arranged within a retaining ring and this ring is rotatably mounted in an angular range of at least 180 °.
  • Such a configuration allows a particularly comfortable movement of the thermal sensor plates and a precise adjustment to the chest of the patient.
  • Procedure with 5 shots from 5 different perspectives offers the possibility of a 3D model of the breast with the regions of interest projected in it.
  • the ROI ' s can be determined in their respective location.
  • the benefits to breast-conserving (BE) surgical planning resulting from a 3D presentation are large.
  • For the 3D representation is still a 3D recording of the breast in a natural position, ie without compression, advantageous.
  • Diagnosis of a suspicious lesion often requires histological clarification for further diagnostic or therapeutic procedures.
  • the exact localization of the lesion for removal of tissue which is required for this purpose, is an expensive procedure for many of the conventional examination methods, such as mammography or MRI.
  • an examination procedure will, if possible, be simpler, lighter and less invasive great apparatusiven effort
  • a localization should be performed using the same method as the diagnosis. This is the only way to ensure that tissue is taken from the same lesion and the same area of the lesion. This requirement finds particular justification for localizations in the region of the easily deformable tissue of the glandular body of the female breast.
  • clamping frame can be achieved.
  • Fig. La is a schematic side view of an inventive
  • FIG. 1b is a schematic top view of the device.
  • Fig. 2a is a schematic view from the inside of one of the two
  • 2b is a schematic view from the inside of a
  • FIG. 3a shows a schematic representation of the tilted thermal
  • FIG. 3b is a schematic representation of a non-parallel
  • Fig. 4 is a schematic side view of another
  • Fig. 5 is a schematic view of the further invention
  • FIG. 6 is a schematic representation of the region of the breast which is detected by the device according to the invention.
  • Fig. 7 a thermal test film with a bandwidth of 26 ° C to 38 ° C.
  • FIG. 8a shows a schematic representation of a breast with a lesion and the heat distribution emanating therefrom.
  • FIG. 8b shows a schematic representation of a breast with a lesion and the heat distribution proceeding therefrom on the surface.
  • FIG. 9 shows a thermo-arrangement according to the invention with it
  • Fig. La shows a schematic side view of an inventive
  • thermo-arrangements 1 with housing 2 is shown in rear view here in the position for a lateral admission of the breast in the so-called "oblique" admission. Arrangement slightly compressed, so that a contact surface of the two thermosensor plate is formed with the outside and inside of the chest
  • the thermo-assemblies 1 are each connected to a support 3 with a pedestal 4 and are adjustable in height
  • the thermo arrangements are in turn rotatable in their entirety by 90 ° about an imaginary axis lying between the holders 3.
  • a heat exchanger 5 In the vertical column 4 there is a heat exchanger 5, which is connected by a hose connection 6 to a thermostat 7 In a part of the heat exchanger 10, the temperature required for the cooling process by a heating coil with W exchanger tightly regulated and kept constant.
  • thermo-arrangements Through a separate circuit 11, the connection to the cooling plates 12 (see also Fig. 2) is made in the thermo-arrangements.
  • a 3-D camera 14 for 3D display is provided.
  • a computer 8 evaluates the recorded measured values.
  • Fig. Lb shows a schematic view of the device seen from above. The two thermo-arrangements la and lb with the housing 2a and 2b and the digital cameras 13a and 13b and foil 15a and 15b are in the "oblique"
  • the 3-D camera 14 is positioned to detect the area of the breast 20 that has no contact with the thermo-arrays 1a and 1b at either the "oblique” setting or the "Cc" setting.
  • Fig. Lb not shown are hoses that bring the cooling medium from the refrigerator 7 to the thermal arrangements la, lb.
  • Figure 2a shows schematically a thermal arrangement 1 in cross-section with the film 15, the cooling plate in the cooling position 12a and in the rest position 12b, the
  • Digital camera 13 the lighting 16a and 16b a modified parabolic reflector screen 17, an embedded software device 18 and the mechatronics 19 for the forward and backward movement of the cooling plate.
  • the use of a parabolic reflector screen 17 makes it possible to reduce reflections from the film 15 and thus allows a more accurate recording of the film 15 by the camera 13th
  • Fig. 2b shows a further thermal arrangement 1, in which the removal of the cooling plate takes place via a folding mechanism.
  • Fig. 3a shows schematically the tilted thermo-arrangements la and lb, the pedestal 4 and therein contained heat exchanger 5.
  • the tilting direction 21 is shown schematically by dashed arrows. It is understood that in addition to the tilted in 90 ° state and tilting conditions with angles between 0 ° and 90 ° are possible. It can also be provided a locking device with which the thermal assemblies la, lb are locked in a certain angle state.
  • FIG. 3 b shows thermal sensor plates 1 a, 1 b, which are applied at an angle to the breast 20. With an angle of approximately 45 °, a particularly good coverage of the breast can be achieved while at the same time reducing deformation of the breast. The comfort for the patient is thus increased.
  • Fig. 4 shows in front view another device according to the invention.
  • an annular guide rail 31 is provided, in which a second annular mounting rail 33 can be moved.
  • On the mounting rail 33 are shown schematically here, shown in two different positions, the thermo-arrangements 38 for the position of the "Cc" recording and in another position 34 for the "oblique” recording.
  • the heat exchangers 32, 34 are shown behind the thermo-assemblies 38 in the view shown.
  • the 3D camera 37 is between the thermal assemblies 38
  • the uprights 35, 36 carry the entire arrangement.
  • Fig. 5 shows the device of Fig. 4 in side view.
  • the mounting rail 33 is arranged on the annular rigid guide rail 31.
  • the mounting rail of the heat exchanger 32 is attached to the thermal sensor plates 38.
  • the position of the breast is represented by 39.
  • the position of the 3-D camera is designated 37.
  • Fig. 6 shows schematically the region of the breast which is detected by the device according to the invention.
  • the skin area of the breast which has no contact with the thermal sensor plates is designated 41.
  • the surface 41 and the contour 42 of the breast is digitally detected by a 3-D camera 37.
  • the position of the nipple 43 is detected exactly.
  • the contour is projected onto the thermo-optical representation, so that a direct comparison of the localization of a lesion on the thermographic image with that on the mammography can be made.
  • Fig. 7 shows schematically the structure of a test film having a bandwidth of 26 ° C to 38 ° C. Apply the slide to the chest of a new one too
  • FIGS. 8a and 8b show schematically how the position of a heat source
  • isotherm 62 algorithmically determined by isotherm 62.
  • the heat flows from the place of origin according to the second law of thermodynamics in the direction of lower temperature, ie to the body surface.
  • the heat is distributed approximately along a vector 61 perpendicular to the body surface, but also horizontally.
  • the distances between the isotherms 62 and the center of the vector allow algorithmic conclusions to be drawn about the depth localization of the vector
  • thermosensor plate By taking into account the corresponding values which result on the opposite thermosensor plate, an estimate of the 3D position of the lesion is possible if the distances of the thermosensor plates are known.
  • thermo-arrangement 1 shows a schematic representation of a thermo-arrangement 1, the side of which facing the breast 20 is provided with a clamping frame 70 and a tightly stretched, transparent tensioning frame film 71.
  • a protective film 72 located on the breast side is removed from the tenter foil 71. Thereafter, the self-adhesive coating of the clamping frame film 71 is free and pressed together with clamping frame 70 on the chest.
  • the protective film which is on the side facing away from the chest
  • clamping frame 70 together with clamping frame film 71 is fixed to the holding frame. Then the usual examination is carried out. After removal of the thermal arrangement 1, the evaluation of the recorded takes place
  • ROI relevant regions of interest
  • the clamping frame 70 with the tenter foil 71 for fixing the breast 20 to the affected breast 20 and the respective quadrant of the patient can be placed.
  • the thermo-arrangement 1 is accurately inserted into the clamping frame 70 and with its thermo-optical film 15 with the clamping frame film 71 in contact brought.
  • a thermo-optical native image builds up.
  • the images stored in HD format are examined for the lesion and marked.
  • the striking position of the ROI can then be projected onto the tenter foil by marking on a display.

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Abstract

L'invention concerne un dispositif pour l'examen thermique du sein féminin (20), comprenant une première et une seconde plaque de détection thermique (15a, 15b) pour la mesure de la température du sein (20), un dispositif de refroidissement (12a, 12b) pour refroidir le sein (20) et une unité d'évaluation (8) pour évaluer les températures mesurées, les plaques de détection thermique (15a, 15b) pouvant être orientées l'une relativement à l'autre de telle manière que le sein (20) est serré entre les deux plaques de détection thermique.
PCT/EP2013/060026 2012-05-22 2013-05-15 Dispositif et procédé d'examen thermique du sein féminin WO2013174691A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102012104419A DE102012104419B3 (de) 2012-05-22 2012-05-22 Vorrichtung und Verfahren zur thermischen Untersuchung der weiblichen Brust
DE102012104419.8 2012-05-22

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WO2013174691A1 true WO2013174691A1 (fr) 2013-11-28

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WO (1) WO2013174691A1 (fr)

Cited By (1)

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US4005166A (en) 1975-05-27 1977-01-25 International Paper Company Process of molding a catheter
WO1979000594A1 (fr) 1978-02-06 1979-08-23 K Schlager Appareil thermographique pour l'examen de patients
DE8326341U1 (de) 1984-01-19 Röhm Pharma GmbH, 6108 Weiterstadt Kompaktvorrichtung zur photographischen Dokumentation der Platten-Thermographie
WO1985000508A1 (fr) 1983-07-20 1985-02-14 American Thermometer Co., Inc. Dispositif de detection, de mesure et d'enregistrement du pouvoir d'emission thermique d'un corps
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WO2000064332A1 (fr) 1999-04-22 2000-11-02 Heinrich Wehberg Dispositif pour effectuer des prises de vue thermo-optiques du sein
DE20019614U1 (de) * 2000-11-19 2001-01-18 Wehberg Heinrich Kühlvorrichtung für thermooptische Platte
DE20102858U1 (de) 2001-02-19 2001-06-07 Wehberg Heinrich Vorrichtung für thermooptische Bilder mit Kühlung durch Peltier Elemente und wegklappbarem Kühlschild

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DE8326341U1 (de) 1984-01-19 Röhm Pharma GmbH, 6108 Weiterstadt Kompaktvorrichtung zur photographischen Dokumentation der Platten-Thermographie
US3970074A (en) 1974-08-22 1976-07-20 Spitalul Clinic Filantropia Bucuresti Method of and apparatus for making medical thermographs
US4005166A (en) 1975-05-27 1977-01-25 International Paper Company Process of molding a catheter
WO1979000594A1 (fr) 1978-02-06 1979-08-23 K Schlager Appareil thermographique pour l'examen de patients
WO1985000508A1 (fr) 1983-07-20 1985-02-14 American Thermometer Co., Inc. Dispositif de detection, de mesure et d'enregistrement du pouvoir d'emission thermique d'un corps
WO1986003017A1 (fr) * 1984-11-15 1986-05-22 I.P.S., International Products & Services S.R.L. Procede et appareil de prise de vues photographiques de plaques de detection thermographique
US4774961A (en) * 1985-11-07 1988-10-04 M/A Com, Inc. Multiple antennae breast screening system
WO2000064332A1 (fr) 1999-04-22 2000-11-02 Heinrich Wehberg Dispositif pour effectuer des prises de vue thermo-optiques du sein
DE20019614U1 (de) * 2000-11-19 2001-01-18 Wehberg Heinrich Kühlvorrichtung für thermooptische Platte
DE20102858U1 (de) 2001-02-19 2001-06-07 Wehberg Heinrich Vorrichtung für thermooptische Bilder mit Kühlung durch Peltier Elemente und wegklappbarem Kühlschild

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021052717A1 (fr) * 2019-09-19 2021-03-25 Medizintechnik Wehberg GmbH Appareil et procédé de thermographie

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