WO2013166338A3 - Système de capture cellulaire et son utilisation - Google Patents
Système de capture cellulaire et son utilisation Download PDFInfo
- Publication number
- WO2013166338A3 WO2013166338A3 PCT/US2013/039350 US2013039350W WO2013166338A3 WO 2013166338 A3 WO2013166338 A3 WO 2013166338A3 US 2013039350 W US2013039350 W US 2013039350W WO 2013166338 A3 WO2013166338 A3 WO 2013166338A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- capture system
- cell capture
- cells
- cell
- determining
- Prior art date
Links
- 239000007788 liquid Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/069—Absorbents; Gels to retain a fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
- G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Clinical Laboratory Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Optics & Photonics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dispersion Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015510466A JP6240162B2 (ja) | 2012-05-02 | 2013-05-02 | 細胞収集システムおよびその使用 |
CN201380035711.6A CN104685346B (zh) | 2012-05-02 | 2013-05-02 | 细胞捕获系统及其使用 |
EP13730385.5A EP2769204B1 (fr) | 2012-05-02 | 2013-05-02 | Système de capture cellulaire et son utilisation |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261641812P | 2012-05-02 | 2012-05-02 | |
US61/641,812 | 2012-05-02 | ||
US201361784807P | 2013-03-14 | 2013-03-14 | |
US61/784,807 | 2013-03-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2013166338A2 WO2013166338A2 (fr) | 2013-11-07 |
WO2013166338A3 true WO2013166338A3 (fr) | 2014-01-09 |
Family
ID=48670054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2013/039350 WO2013166338A2 (fr) | 2012-05-02 | 2013-05-02 | Système de capture cellulaire et son utilisation |
Country Status (5)
Country | Link |
---|---|
US (2) | US10324036B2 (fr) |
EP (1) | EP2769204B1 (fr) |
JP (1) | JP6240162B2 (fr) |
CN (1) | CN104685346B (fr) |
WO (1) | WO2013166338A2 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104662425B (zh) | 2012-05-02 | 2017-10-10 | 查尔斯河实验室公司 | 活性染色方法 |
EP2769204B1 (fr) | 2012-05-02 | 2016-02-17 | Charles River Laboratories, Inc. | Système de capture cellulaire et son utilisation |
US9709500B2 (en) | 2012-05-02 | 2017-07-18 | Charles River Laboratories, Inc. | Optical method for detecting viable microorganisms in a cell sample |
WO2015066727A1 (fr) * | 2013-11-04 | 2015-05-07 | Charles River Laboratories, Inc. | Procédé de détection de cellules viables dans un échantillon de cellules |
JP6556155B2 (ja) | 2013-11-04 | 2019-08-07 | チャールズ リバー ラボラトリーズ, インコーポレイテッド | ろ過システム及びその用途 |
US9436866B2 (en) | 2014-08-01 | 2016-09-06 | General Electric Company | High sensitivity flat panel microbiology detection and enumeration system |
EP3427024A4 (fr) * | 2016-02-18 | 2019-11-06 | Optofluidics, Inc. | Système et procédé de caractérisation de particules dans un échantillon de fluide |
US11035795B2 (en) | 2016-02-18 | 2021-06-15 | Optofluidics, Inc. | Methods for identification of particles in a fluid sample |
GB201716883D0 (en) * | 2017-10-13 | 2017-11-29 | Q-Linea Ab | Method for determining the concentration of intact microorganisms in a sample |
US11609224B2 (en) | 2017-10-26 | 2023-03-21 | Essenlix Corporation | Devices and methods for white blood cell analyses |
EP3784368A4 (fr) * | 2018-04-25 | 2022-01-26 | Optofluidics, Inc. | Collecteur à vide pour microscopie à filtration |
CN113260860A (zh) | 2018-08-16 | 2021-08-13 | Essenlix 公司 | 体液,特别是血液中的细胞分析 |
EP3884329A4 (fr) | 2018-11-21 | 2022-11-09 | Cornell University | Solutions d'extinction de clarification optique et d'extinction d'auto-fluorescence et procédé d'utilisation pour l'imagerie de microscopie améliorée de tissus biologiques |
CN111007238A (zh) * | 2019-11-27 | 2020-04-14 | 爱威科技股份有限公司 | 一种富集器、富集系统、样本制造系统和样本检测系统 |
US11000780B1 (en) * | 2019-12-06 | 2021-05-11 | AnuCell Biosystems Limited | Torus reactor for a combined cell isolator and bioreactor |
WO2022011169A1 (fr) * | 2020-07-08 | 2022-01-13 | Rapid Micro Biosystems, Inc. | Ensembles filtration, cassettes, systèmes et procédés de filtration et de croissance cellulaire |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0713087A1 (fr) * | 1994-11-17 | 1996-05-22 | Chemunex | Appareil et procédé de détection et de numération rapides et ultrasensibles de micro-organismes par fluorescence |
WO2003022999A2 (fr) * | 2001-09-06 | 2003-03-20 | Genomic Profiling Systems, Inc. | Detection rapide de cellules de replication |
US20060129327A1 (en) * | 2004-07-29 | 2006-06-15 | Kim Myung L | Ultrasensitive sensor and rapid detection of analytes |
US20080305514A1 (en) * | 2007-06-06 | 2008-12-11 | Alcon Research, Ltd. | Method for detecting microbes |
WO2010006615A2 (fr) * | 2008-07-14 | 2010-01-21 | Chemometec A/S | Procédé et trousse permettant d'évaluer la viabilité cellulaire |
Family Cites Families (104)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1256360A (fr) | 1984-02-10 | 1989-06-27 | John W. Bornhoeft | Dispositif et methode pour determiner l'efficacite de la sterilisation |
WO1986005206A1 (fr) | 1985-02-27 | 1986-09-12 | University Of Cincinnati | Detection de microorganismes viables par induction de fluorescence |
US4739416A (en) | 1986-09-15 | 1988-04-19 | Matrix Instruments Inc. | Digital image reproduction |
US4725891A (en) | 1986-09-15 | 1988-02-16 | Matrix Instruments Inc. | Film image digitizer |
US4783401A (en) | 1986-10-31 | 1988-11-08 | Smithkline Beckman Corporation | Viable cell labelling |
US4930893A (en) | 1988-03-25 | 1990-06-05 | Molecular Dynamics | Electrophoresis imaging system |
US4838632A (en) | 1988-05-06 | 1989-06-13 | Lumisys Inc. | Two-dimensional beam scanner |
US5073488A (en) | 1988-11-29 | 1991-12-17 | Minnesota Mining And Manufacturing Company | Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator |
WO1992002632A1 (fr) | 1990-07-30 | 1992-02-20 | Sierra Cytometry | Colorants fluorescents d'identification et d'enumeration de cellules viables dans le lait |
US5185450A (en) | 1991-02-19 | 1993-02-09 | University Of South Florida | Tetrazolium compounds for cell viability assays |
US5172419A (en) | 1991-03-05 | 1992-12-15 | Lumisys, Inc. | Medical image processing system |
US5296341A (en) | 1991-03-05 | 1994-03-22 | Lumisys, Inc. | Green light laser imaging method |
US5314805A (en) | 1991-10-28 | 1994-05-24 | Molecular Probes, Inc. | Dual-fluorescence cell viability assay using ethidium homodimer and calcein AM |
US5137609A (en) | 1992-01-31 | 1992-08-11 | Biometric Imaging Inc. | Differential separation assay |
US5221454A (en) | 1992-01-31 | 1993-06-22 | Biometric Imaging Inc. | Differential separation assay |
US5843680A (en) | 1992-01-31 | 1998-12-01 | Biometric Imaging, Inc. | Differential separation assay methods and test kits |
DE69311944T2 (de) | 1992-04-01 | 1997-11-20 | Nihon Millipore Kogyo K K | Verfahren zur Bestimmung der Anzahl lebender Mikroorganismen |
JP3228812B2 (ja) | 1993-02-10 | 2001-11-12 | 日本マイクロリス株式会社 | 生菌数を測定する方法 |
US5547849A (en) | 1993-02-17 | 1996-08-20 | Biometric Imaging, Inc. | Apparatus and method for volumetric capillary cytometry |
US5585246A (en) | 1993-02-17 | 1996-12-17 | Biometric Imaging, Inc. | Method for preparing a sample in a scan capillary for immunofluorescent interrogation |
US5545535A (en) | 1993-04-13 | 1996-08-13 | Molecular Probes, Inc. | Fluorescent assay for bacterial gram reaction |
US5445946A (en) | 1993-04-13 | 1995-08-29 | Molecular Probes, Inc. | Intravacuolar stains for yeast and other fungi |
US5534416A (en) | 1993-04-13 | 1996-07-09 | Molecular Probes, Inc. | Fluorescent viability assay using cyclic-substituted unsymmetrical cyanine dyes |
US5658751A (en) | 1993-04-13 | 1997-08-19 | Molecular Probes, Inc. | Substituted unsymmetrical cyanine dyes with selected permeability |
US5436134A (en) | 1993-04-13 | 1995-07-25 | Molecular Probes, Inc. | Cyclic-substituted unsymmetrical cyanine dyes |
US5437980A (en) | 1993-05-17 | 1995-08-01 | Molecular Probes, Inc. | Phenanthridium dye staining of nucleic acids in living cells |
FR2707665A1 (fr) | 1993-06-28 | 1995-01-20 | Chemunex | Procédé de mesure et d'évaluation de la vitalité des microorganismes et ses applications. |
JP3011036B2 (ja) | 1993-12-20 | 2000-02-21 | 三菱化学株式会社 | 光ディスク基板の複屈折の測定法 |
IES940182A2 (en) | 1994-03-01 | 1995-11-29 | Teagasc Agric Food Dev Authori | "Rapid detection of bacteria in liquid cultures" |
JP3137160B2 (ja) | 1994-04-01 | 2001-02-19 | 日立電子エンジニアリング株式会社 | ウエハの位置ズレ補正方法 |
US5550032A (en) | 1994-05-27 | 1996-08-27 | George Mason University | Biological assay for microbial contamination |
JP3593161B2 (ja) | 1994-11-15 | 2004-11-24 | 株式会社トプコン | 回転体上異物位置測定装置 |
US5603900A (en) * | 1995-05-19 | 1997-02-18 | Millipore Investment Holdings Limited | Vacuum filter device |
US5565678A (en) | 1995-06-06 | 1996-10-15 | Lumisys, Inc. | Radiographic image quality assessment utilizing a stepped calibration target |
WO1997012226A1 (fr) | 1995-09-25 | 1997-04-03 | Tencor Instruments | Systeme ameliore d'examen de surface |
WO1997017463A1 (fr) | 1995-11-08 | 1997-05-15 | Pioneer Hi-Bred International, Inc. | Procedes de determination de la viabilite de cultures microbiennes |
WO1997024616A1 (fr) | 1995-12-29 | 1997-07-10 | Ishihara Sangyo Kaisha, Ltd. | Procede de determination du taux de viabilite de cellules |
US6459805B1 (en) | 1996-03-26 | 2002-10-01 | Childrens Hospital Los Angeles | Fluorescence digital imaging microscopy system |
DE19621312A1 (de) | 1996-05-28 | 1997-12-04 | Bayer Ag | Maskierung der Hintergrundfluoreszenz und Signalverstärkung bei der optischen Analyse biologisch medizinischer Assays |
US5956146A (en) | 1997-01-29 | 1999-09-21 | Victor Company Of Japan, Ltd. | Birefringence measuring apparatus for optical disc substrate |
US6221621B1 (en) | 1997-03-06 | 2001-04-24 | Bard Diagnostic Sciences, Inc. | Methods of screening for colorectal cancers in which a complement Factor I or related protein is associated |
FR2764305B1 (fr) | 1997-06-04 | 2000-10-06 | Chemunex | Procede de detection et de numeration de cellules viables dans un echantillon biologique et kit pour sa mise en oeuvre |
US6221612B1 (en) | 1997-08-01 | 2001-04-24 | Aurora Biosciences Corporation | Photon reducing agents for use in fluorescence assays |
US6200762B1 (en) | 1997-08-01 | 2001-03-13 | Aurora Biosciences Corporation | Photon reducing agents and compositions for fluorescence assays |
US6214563B1 (en) | 1997-08-01 | 2001-04-10 | Aurora Biosciences Corporation | Photon reducing agents for reducing undesired light emission in assays |
US6043506A (en) | 1997-08-13 | 2000-03-28 | Bio-Rad Laboratories, Inc. | Multi parameter scanner |
US5922617A (en) | 1997-11-12 | 1999-07-13 | Functional Genetics, Inc. | Rapid screening assay methods and devices |
BR9814726A (pt) | 1997-12-30 | 2000-10-17 | Jose Remacle | Método compreendendo molécula de captura fixada em superficìe de disco |
US6080868A (en) | 1998-01-23 | 2000-06-27 | The Perkin-Elmer Corporation | Nitro-substituted non-fluorescent asymmetric cyanine dye compounds |
WO2000007007A1 (fr) | 1998-07-28 | 2000-02-10 | Biometric Imaging, Inc. | Dispositif et methode d'analyse de motilite cellulaire |
US6130745A (en) | 1999-01-07 | 2000-10-10 | Biometric Imaging, Inc. | Optical autofocus for use with microtiter plates |
CA2362117C (fr) | 1999-02-26 | 2004-11-30 | Cellomics, Inc. | Systeme de criblage cellulaire |
JP2000304688A (ja) | 1999-04-16 | 2000-11-02 | Canon Inc | 基板測定方法および装置 |
US6181413B1 (en) | 1999-09-03 | 2001-01-30 | Biometric Imaging, Inc. | Displacing volume in field of view |
CA2427106C (fr) | 1999-10-25 | 2014-09-16 | Genprime, Inc. | Methode et appareil de quantification de cellules procaryotes et eucaryotes |
JP2001228088A (ja) | 2000-02-18 | 2001-08-24 | Nippon Laser & Electronics Lab | 生体試料光学的走査装置 |
JP2001242082A (ja) | 2000-02-29 | 2001-09-07 | Nippon Laser & Electronics Lab | 生体試料光学的走査装置 |
GB0008787D0 (en) | 2000-04-10 | 2000-05-31 | Norsk Naeringsmiddelforskning | A method of cell detection |
US6323337B1 (en) | 2000-05-12 | 2001-11-27 | Molecular Probes, Inc. | Quenching oligonucleotides |
US7118878B1 (en) | 2000-06-09 | 2006-10-10 | Promega Corporation | Method for increasing luminescence assay sensitivity |
IL139593A (en) | 2000-11-09 | 2010-12-30 | Biogem Optical Ltd | Method for the detection of viable microorganisms |
US6633368B2 (en) | 2001-01-02 | 2003-10-14 | Becton, Dickinson And Company | Method for determining the volume of single red blood cells |
US6714287B2 (en) | 2001-01-02 | 2004-03-30 | Becton, Dickinson And Company | Apparatus for determining the volume of single red blood cells |
US20020098531A1 (en) | 2001-01-25 | 2002-07-25 | Thacker James D. | Rapid methods for microbial typing and enumeration |
US7016087B2 (en) | 2001-08-08 | 2006-03-21 | Becton Dickinson And Company | Photon efficient scanner |
US6750457B2 (en) | 2001-08-29 | 2004-06-15 | Becton Dickinson And Company | System for high throughput analysis |
US7205100B2 (en) | 2002-10-10 | 2007-04-17 | Advanced Analytical Technologies, Inc. | Methods for reducing background fluorescence |
ES2239886B1 (es) | 2003-11-05 | 2006-12-16 | Universidad De Barcelona | Metodo y aparato para la determinacion de la viabilidad celular. |
EP1699351B1 (fr) | 2003-12-22 | 2011-05-04 | Lightouch Medical, Inc. | Procede permettant de determiner la viabilite des cellules |
EP1728069A4 (fr) | 2004-03-17 | 2009-08-19 | Ca Nat Research Council | Procede et dispositif servant a detecter des micro-organismes |
CN101432739A (zh) * | 2004-07-29 | 2009-05-13 | 金实验室公司 | 超灵敏传感器和分析物的快速检测 |
DE602005010515D1 (de) | 2004-08-06 | 2008-12-04 | Fuji Electric Holdings | Nachweisverfahren für lebenfähige Zellen |
JP4779433B2 (ja) * | 2004-08-26 | 2011-09-28 | パナソニック株式会社 | ろ過フィルタデバイス |
US7018804B1 (en) | 2004-12-03 | 2006-03-28 | Orion Biosolutions, Inc. | Determination of cell viability and phenotype |
US20060121443A1 (en) | 2004-12-03 | 2006-06-08 | Orion Biosolutions, Inc. | Determination of cell viability |
WO2006091630A2 (fr) | 2005-02-22 | 2006-08-31 | University Of Cincinnati | Utilisation de billes paramagnetiques enduites pour evaluer des micro-organismes viables |
US8268567B2 (en) | 2005-09-16 | 2012-09-18 | The Charles Stark Draper Laboratory | Reaction sensing in living cells |
JP5268175B2 (ja) | 2006-01-12 | 2013-08-21 | バイオセンス テクノロジーズ インク. | 迅速に細胞の生存テストを実行するための方法及び構成物 |
DE102006022877B4 (de) | 2006-05-15 | 2009-01-29 | Sartorius Stedim Biotech Gmbh | Verfahren zur Bestimmung der Viabilität von Zellen in Zellkulturen |
GB0615302D0 (en) | 2006-08-01 | 2006-09-13 | Biotrace Internat Plc | Assay Method For The Detection Of Viable Microbial Cells In A Sample |
US20080153125A1 (en) | 2006-11-10 | 2008-06-26 | Advanced Analytical Technologies, Inc. | Rapid detection of microorganisms in fluids |
AU2008239654A1 (en) | 2007-04-13 | 2008-10-23 | Promega Corporation | Luminescent live and dead cell assay |
WO2009029039A1 (fr) | 2007-08-28 | 2009-03-05 | Ridgeview Instruments Ab | Procédé de mesure de la viabilité d'une cellule |
JP2011503579A (ja) | 2007-11-09 | 2011-01-27 | ジェンザイム・コーポレーション | 対照細胞を使用しない細胞生存率の測定方法 |
EP2232243B1 (fr) | 2007-12-20 | 2015-12-16 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | Procédé en temps réel pour la détection de micro-organismes viables |
JP2011519959A (ja) | 2008-05-13 | 2011-07-14 | ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ | 破壊された細胞膜を有する細胞、病原体に感染した細胞、死にかけている細胞または死細胞を検出する方法 |
ES2540544T3 (es) | 2009-05-04 | 2015-07-10 | Novartis Ag | Microensayo rápido de esterilidad |
FR2945457B1 (fr) * | 2009-05-12 | 2011-07-15 | Aes Chemunex | Ensemble forme d'une membrane de filtration et d'une plaque de support, ainsi que dispositif de test microbiologique en faisant usage. |
US8148515B1 (en) | 2009-06-02 | 2012-04-03 | Biotium, Inc. | Detection using a dye and a dye modifier |
WO2010151131A2 (fr) | 2009-06-26 | 2010-12-29 | Nederlandse Organisatie Voor Toegepast- Natuurwetenschappelijk Onderzoek Tno | Appareil pour la detection de microorganismes ou spores viables dans un echantillon et son utilisation |
JP4825313B2 (ja) | 2009-07-24 | 2011-11-30 | 森永乳業株式会社 | 微生物検出法及び微生物検出キット |
US20120244571A1 (en) | 2010-03-26 | 2012-09-27 | Morinaga Milk Industry Co. Ltd | Measurement method for viable cell count, and culture medium |
GB201005939D0 (en) | 2010-04-09 | 2010-05-26 | Biostatus Ltd | Method of analysing a cell or other biological material containing nucleic acid |
US20110294206A1 (en) | 2010-05-28 | 2011-12-01 | California Institute Of Technology | Methods and design of membrane filters |
CN102971433A (zh) | 2010-06-03 | 2013-03-13 | 巴斯夫欧洲公司 | 微生物的检测和计数 |
WO2012051437A1 (fr) | 2010-10-13 | 2012-04-19 | Life Technologies Corporation | Compositions et essais pour déterminer une viabilité cellulaire |
WO2012059785A1 (fr) | 2010-11-03 | 2012-05-10 | Reametrix Inc. | Procédés pour étalonner un spectromètre raman, et spectromètre |
WO2012059784A1 (fr) | 2010-11-03 | 2012-05-10 | Reametrix Inc | Procédé et dispositif de mesure de fluorescence d'échantillons |
EP2635895A1 (fr) | 2010-11-03 | 2013-09-11 | Reametrix Inc. | Système de mesure pour la détection de fluorescence, et procédé associé |
EP2637787A1 (fr) | 2010-11-08 | 2013-09-18 | Reactrix Systems, Inc. | Ensemble échantillon pour un dispositif de mesure |
US9446411B2 (en) | 2011-02-24 | 2016-09-20 | Reametrix, Inc. | Sample assembly for a measurement device |
EP2769204B1 (fr) | 2012-05-02 | 2016-02-17 | Charles River Laboratories, Inc. | Système de capture cellulaire et son utilisation |
CN104662425B (zh) | 2012-05-02 | 2017-10-10 | 查尔斯河实验室公司 | 活性染色方法 |
US9709500B2 (en) | 2012-05-02 | 2017-07-18 | Charles River Laboratories, Inc. | Optical method for detecting viable microorganisms in a cell sample |
-
2013
- 2013-05-02 EP EP13730385.5A patent/EP2769204B1/fr active Active
- 2013-05-02 CN CN201380035711.6A patent/CN104685346B/zh not_active Expired - Fee Related
- 2013-05-02 US US13/875,969 patent/US10324036B2/en not_active Expired - Fee Related
- 2013-05-02 WO PCT/US2013/039350 patent/WO2013166338A2/fr active Application Filing
- 2013-05-02 JP JP2015510466A patent/JP6240162B2/ja not_active Expired - Fee Related
-
2019
- 2019-02-25 US US16/284,495 patent/US10976258B2/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0713087A1 (fr) * | 1994-11-17 | 1996-05-22 | Chemunex | Appareil et procédé de détection et de numération rapides et ultrasensibles de micro-organismes par fluorescence |
WO2003022999A2 (fr) * | 2001-09-06 | 2003-03-20 | Genomic Profiling Systems, Inc. | Detection rapide de cellules de replication |
US20060129327A1 (en) * | 2004-07-29 | 2006-06-15 | Kim Myung L | Ultrasensitive sensor and rapid detection of analytes |
US20080305514A1 (en) * | 2007-06-06 | 2008-12-11 | Alcon Research, Ltd. | Method for detecting microbes |
WO2010006615A2 (fr) * | 2008-07-14 | 2010-01-21 | Chemometec A/S | Procédé et trousse permettant d'évaluer la viabilité cellulaire |
Also Published As
Publication number | Publication date |
---|---|
JP6240162B2 (ja) | 2017-11-29 |
EP2769204A2 (fr) | 2014-08-27 |
WO2013166338A2 (fr) | 2013-11-07 |
US10324036B2 (en) | 2019-06-18 |
EP2769204B1 (fr) | 2016-02-17 |
US20190187056A1 (en) | 2019-06-20 |
CN104685346B (zh) | 2018-05-29 |
US10976258B2 (en) | 2021-04-13 |
US20130316363A1 (en) | 2013-11-28 |
JP2015521038A (ja) | 2015-07-27 |
CN104685346A (zh) | 2015-06-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2013166338A3 (fr) | Système de capture cellulaire et son utilisation | |
IL257714B (en) | Systems and methods for the analysis of multiple analytes | |
WO2014083435A3 (fr) | Manipulation d'échantillons de liquide | |
WO2014028378A3 (fr) | Procédés et systèmes de détection de composants biologiques | |
EP3105326A4 (fr) | Dispositif de préparation de banque d'acides nucléiques médiée par des cellules à liquides composites (clc), et ses procédés d'utilisation | |
WO2013159035A8 (fr) | Surveillance hautement sensible utilisant une détection d'adn acellulaire | |
WO2011094572A3 (fr) | Dispositifs, systèmes et/ou procédés pour cultures en gouttes suspendues | |
SG11201406039WA (en) | Systems and methods for containing biological samples | |
EP2927311A4 (fr) | Dispositif d'observation de cellule, méthode d'observation de cellule et programme correspondant | |
GB201218555D0 (en) | Immunoassay using electrochemical detection | |
EP2729784A4 (fr) | Cellule échantillon pour système d'analyse de fluide | |
EP3701045A4 (fr) | Améliorations de l'analyse cellulaire ou relatives à cette dernière | |
EP3087633A4 (fr) | Reequilibrage de concentration d'electrolyte dans une batterie redox au moyen de la difference de pression | |
EP3092476A4 (fr) | Structure et procédé pour indiquer des constituants indésirables dans un système de pile à combustible | |
AU2015297746B2 (en) | electrolyte for redox flow battery and redox flow battery system | |
AU2014317495A1 (en) | Liquid electrolyte for an electrochemical gas sensor | |
EP2902476A4 (fr) | Dispositif de préparation d'échantillons, dispositif d'analyse de cellules, et élément filtre | |
EP2855695A4 (fr) | Systèmes, procédés et composants permettant d'isoler les cellules d'un échantillon fluide | |
EP2859340A4 (fr) | Systèmes et procédés de détection électrochimique multiplexée | |
WO2011119986A3 (fr) | Procédés de culture et d'analyse de cellules | |
EP2534727A4 (fr) | Cellule de détection électrochimique pour un système de chromatographie en phase liquide | |
EP2912267A4 (fr) | Systèmes et procédés pour collecter une ou plusieurs mesures et/ou échantillons | |
EP3072953A4 (fr) | Récipient de culture de cellules et récipient dans lequel une culture de cellule a été logée | |
EP2879581A4 (fr) | Cuves de récupération de liquides biologiques, systèmes et procédés | |
EP2905330A4 (fr) | Élément de culture cellulaire, et procédé de culture cellulaire |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 13730385 Country of ref document: EP Kind code of ref document: A2 |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2013730385 Country of ref document: EP |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 13730385 Country of ref document: EP Kind code of ref document: A2 |
|
ENP | Entry into the national phase |
Ref document number: 2015510466 Country of ref document: JP Kind code of ref document: A |