WO2013145893A1 - Fil-guide médical - Google Patents

Fil-guide médical Download PDF

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Publication number
WO2013145893A1
WO2013145893A1 PCT/JP2013/053077 JP2013053077W WO2013145893A1 WO 2013145893 A1 WO2013145893 A1 WO 2013145893A1 JP 2013053077 W JP2013053077 W JP 2013053077W WO 2013145893 A1 WO2013145893 A1 WO 2013145893A1
Authority
WO
WIPO (PCT)
Prior art keywords
end side
resin
coil spring
guide wire
rear end
Prior art date
Application number
PCT/JP2013/053077
Other languages
English (en)
Japanese (ja)
Inventor
亮一 奥村
浩範 河崎
Original Assignee
日本ライフライン株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日本ライフライン株式会社 filed Critical 日本ライフライン株式会社
Priority to CN201380004444.6A priority Critical patent/CN104023783B/zh
Priority to KR1020147026779A priority patent/KR101844630B1/ko
Publication of WO2013145893A1 publication Critical patent/WO2013145893A1/fr
Priority to HK15101141.9A priority patent/HK1200746A1/xx

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09058—Basic structures of guide wires
    • A61M2025/09083—Basic structures of guide wires having a coil around a core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09166—Guide wires having radio-opaque features

Definitions

  • the present invention relates to a medical guide wire having a coil spring attached to the outer periphery of a small-diameter portion on the distal end side of a core wire.
  • a guide wire for guiding a medical device such as a catheter to a predetermined position in a body cavity such as a blood vessel requires flexibility and flexibility at the distal end. For this reason, the outer diameter of the distal end portion of the core wire is made smaller than the outer diameter of the proximal end portion, and a coil spring is attached to the outer periphery of the distal end portion (distal end side small diameter portion) of the core wire.
  • a guide wire intended to improve the flexibility of the distal end is known (see Patent Document 1).
  • the inside of the coil spring attached to the distal end portion of the core wire is filled with resin, and a resin layer made of the resin is formed on the outer periphery of the coil spring, and a hydrophilic resin layer is formed on the surface of the resin layer.
  • a laminated guide wire is introduced (see Patent Document 2). By forming the hydrophilic resin layer on the outer periphery of the coil spring, lubricity is imparted to the distal end portion of the guide wire, and the insertion property of the guide wire can be improved.
  • the operator can change the resistance (change) of the blood vessel site with which the distal end of the guide wire is in contact. Is grasped by feeling at hand.
  • the present invention has been made based on the above situation.
  • the object of the present invention is to have a good lubricity at the distal end and a good guide wire insertion property, but it is possible to sufficiently grasp information in the blood vessel as resistance (change) on the hand side.
  • An object of the present invention is to provide a medical guide wire that can be reliably pushed toward a target site.
  • Another object of the present invention is to provide a medical guide wire that can easily perform a shaping operation.
  • the medical guidewire of the present invention includes a core wire having a distal end side small diameter portion and a proximal end side large diameter portion having a larger outer diameter than the distal end side small diameter portion;
  • a medical guide wire having a coil spring attached to the outer periphery of the small-diameter portion on the distal end side of the core wire along the axial direction, and having a coil spring fixed to the core wire at least at the front end portion and the rear end portion;
  • the coil spring includes a close winding portion on the front end side having a coil pitch of 1.0 to 1.8 times the coil wire diameter, and a sparse winding on the rear end side having a coil pitch of 1.8 to 2.5 times the coil wire diameter.
  • the inside of the rear end side loosely wound portion is filled with resin, a resin layer made of the resin is formed on the outer periphery of the rear end side loosely wound portion, and a hydrophilic resin coating layer is laminated on the surface of the resin layer Formed, The outer periphery of the tip side densely wound portion is not covered with resin, and the constituent material (metal) of the coil spring is exposed.
  • the medical guide wire having such a configuration, the outer periphery of the distal-side densely wound portion is not covered with the resin, and the constituent material of the coil spring is exposed, so that the blood vessel into which the guide wire is inserted
  • the information inside can be fully grasped as resistance (change) on the hand side (excellent in information transmission).
  • the wire can be pushed forward reliably (excellent guide wire direction selectivity).
  • the core wire and the coil spring (rear end side loosely wound portion) can be integrated, and the torque transmission and operability of the guide wire can be integrated. Can be improved (excellent torque transmission).
  • a resin layer is formed on the outer periphery of the rear end side loosely wound portion, and a hydrophilic resin coating layer is laminated on the surface of the resin layer, thereby filling the inside of the rear end side loosely wound portion. Since the hydrophilic resin coating layer is laminated on the outer periphery of the rear end side loosely wound portion through the resin layer made of the same resin as the one, the hydrophilic resin coating layer is securely fixed, and the hydrophilic resin is preferably used. Lubricity can be stably expressed (excellent adhesion of the hydrophilic resin coating layer to the outer periphery of the rear end side loosely wound portion).
  • the distal end side closely wound portion is not filled with resin. According to such a configuration, it is possible to sufficiently ensure flexibility and flexibility in the front end side closely wound portion, and it is possible to easily perform a shaping operation in the coil spring (front end side closely wound portion).
  • an outer diameter (D 1 ) of the proximal end side large diameter portion of the core wire and a coil outer diameter (D 2 ) of the coil spring are 0.012 inches or less
  • the coil spring length (L 2 ) is 51 to 800 mm
  • the length (L 21 ) of the tip side densely wound portion is 1 to 50 mm
  • It is preferable that the length (L 22 ) of the rear end side loosely wound portion is 50 to 750 mm.
  • an intermediate portion including the front end side closely wound portion and the rear end side loosely wound portion of the coil spring is fixed to the core wire by solder.
  • a tip portion and an intermediate portion of the coil spring are fixed to the core wire with gold-containing solder.
  • the core wire is made of stainless steel.
  • the medical guidewire of the present invention has good lubricity at the distal end, and has good insertability, while sufficiently grasping information in the blood vessel as resistance (change) on the hand side. Can be pushed forward toward the target site. Further, since the resin is filled in the rear end side loosely wound portion, the torque transmission is excellent. In addition, according to the medical guide wire of the present invention including the distal end side tightly wound portion that is not filled with resin, the shaping operation can be further easily performed.
  • a guide wire 1 shown in FIGS. 1 and 2 includes a core wire 10 having a distal end side small diameter portion 11 and a proximal end side large diameter portion 14 having a larger outer diameter than the distal end side small diameter portion 11, and the core wire 10.
  • a medical guide wire having a coil spring 20 attached to the outer periphery of the distal end side small-diameter portion 11 along the axial direction and fixed to the core wire 10 at the front end portion, the intermediate portion, and the rear end portion,
  • the coil spring 20 includes a front end side closely wound portion 21 having a coil pitch of 1.0 to 1.8 times the coil wire diameter, and a rear end side having a coil pitch of 1.8 to 2.5 times the coil wire diameter.
  • the rear end side loosely wound portion 22 is filled with the cured resin 40, and a resin layer 40A made of the cured resin is formed on the outer periphery of the rear end side loosely wound portion 22 to form the resin.
  • Hydrophilic resin coating layer 50 on the surface of layer 40A On the other hand, the outer periphery of the tip side densely wound portion 21 is not covered with resin, and the constituent material of the coil spring 20 is exposed, and the inside of the tip side closely wound portion 21 is also filled with resin. Not a guide wire.
  • the guide wire 1 of the present embodiment has a core wire 10 and a coil spring 20.
  • the core wire 10 includes a distal end side small diameter portion 11 that is tapered so as to expand in the proximal direction, a tapered portion 13 that expands in the proximal direction, and a proximal end large diameter portion 14.
  • the distal end side small diameter portion 11, the taper portion 13, and the proximal end side large diameter portion 14 are integrally configured by the same wire (for example, a round bar member).
  • the cross section of the taper part 13 and the proximal end side large diameter part 14 is substantially circular.
  • the cross section on the proximal end side of the distal end side small diameter portion 11 is substantially circular, but the distal end side of the distal end side small diameter portion 11 may be formed into a plate shape by compressing the wire. In that case, the cross section is substantially rectangular.
  • the material of the core wire 10 is not particularly limited, and examples thereof include metals such as stainless steel (for example, SUS316, SUS304), gold, platinum, aluminum, tungsten, tantalum, and alloys thereof. Then, it is made of stainless steel.
  • a water repellent resin layer (not shown) is formed on the outer peripheral surface of the core wire 10.
  • the resin constituting the water-repellent resin layer any resin that is used for medical purposes and has water repellency can be used, and suitable resins include fluorine-based resins such as PTFE.
  • the total length (L 1 ) of the guide wire 1 shown in FIG. 2 is, for example, 1500 to 3000 mm, and is 1780 mm if a suitable example is shown.
  • the outer diameter (D 1 ) of the proximal end side large-diameter portion 14 is usually 0.012 inches (0.305 mm) or less, preferably 0.010 inches (0.254 mm) or less, more preferably 0. 0.006 to 0.010 inch, and a preferred example is 0.010 inch.
  • the medical instrument such as a catheter used with the guide wire of the present invention can be reduced in size and further reduced in invasiveness. Can contribute.
  • the maximum outer diameter of the distal end side small-diameter portion 11, is not particularly limited smaller than the inner diameter of the coil spring 20, the outer diameter of the proximal end side large-diameter portion 14 (D 1) 1/5 About 3/5.
  • the coil spring 20 constituting the guide wire 1 of the present embodiment is mounted on the outer periphery of the distal end side small diameter portion 11 of the core wire 10 along the axial direction.
  • the coil spring 20 is formed of a single wire, and has a closely wound end 21 with a coil pitch of 1.0 to 1.8 times the coil wire diameter, and a coil pitch of 1.8 to 2 of the coil wire diameter.
  • the rear end side sparsely wound portion 22 which is .5 times larger, and the tip side densely wound portion 21 and a tip which will be described later constitute an X-ray opaque region.
  • the coil pitch in the front end side densely wound portion 21 is 1.0 to 1.8 times the coil wire diameter, and is 1.0 times as a suitable example.
  • the coil pitch in the rear end side loosely wound portion 22 is 1.8 to 2.5 times the coil wire diameter, and is 2.0 times if a suitable example is shown.
  • good contrast visibility
  • the pitch is the same throughout the coil spring 20, the X-ray non-transparent region becomes long, and the visibility is lowered.
  • the coil outer diameter (D 2 ) of the coil spring 20 is usually 0.012 inch (0.305 mm) or less, preferably 0.010 inch (0.254 mm) or less, more preferably 0.006 to 0.010. Inches are 0.010 inches.
  • the outer diameter (D 1 ) of the proximal end side large diameter portion 14 of the core wire 10 is 0.012 inch or less and the coil outer diameter (D 2 ) of the coil spring 20 is also 0.012 inch or less,
  • the operability when accessing the microchannel is excellent.
  • the outer diameter of the wire constituting the coil spring 20 is not particularly limited, but is preferably 30 to 90 ⁇ m, and 60 ⁇ m is a preferable example.
  • the front end portion, the rear end portion, and the intermediate portion of the coil spring 20 are soldered 31 and 32, respectively. 33 is fixed to the outer periphery of the distal end side small diameter portion 11 of the core wire 10.
  • the tip of the coil spring 20 is fixed to the core wire 10 with solder 31. That is, the solder 31 penetrates into the coil spring 20, and the solder 31 comes into contact with the outer periphery of the core wire 10 (distal end side small diameter portion 11), whereby the tip of the coil spring 20 is fixed to the core wire 10. Yes.
  • a substantially hemispherical tip is formed by solder 31 that has not penetrated into the coil spring 20 at the tip of the coil spring 20.
  • the distal end portion of the guide wire is provided with a rigid end portion by the solder 31 (the distal end portion of the coil spring 20 that can no longer be freely bent by the solder 31 that has penetrated into the coil, and the distal end formed by the solder 31. A rigid part) is formed.
  • an intermediate portion including a boundary region between the front end side densely wound portion 21 and the rear end side loosely wound portion 22 of the coil spring 20 is fixed to the core wire 10 by the solder 32. That is, the solder 32 penetrates into the coil spring 20, and the solder 32 comes into contact with the outer periphery of the core wire 10 (distal end side small diameter portion 11), whereby the intermediate portion of the coil spring 20 is fixed to the core wire 10. Yes.
  • the rear end portion of the coil spring 20 is fixed to the core wire 10 with solder 33. That is, the solder 33 penetrates into the coil spring 20, and the solder 33 comes into contact with the outer periphery of the core wire 10 (distal end side small diameter portion 11), whereby the rear end portion of the coil spring 20 is fixed to the core wire 10. ing.
  • gold-containing solder As the solders 31 and 32 for fixing the tip part and the intermediate part of the coil spring 20 to the core wire 10 respectively.
  • gold-containing solder includes Au alloy solder such as Au—Sn solder, Au—Ge solder, Au—Si solder, Au—In solder, Au—Sb solder, and Au solder. It is.
  • examples of the solder 33 for fixing the rear end portion of the coil spring 20 to the core wire 10 include silver-based solder such as Ag—Sn.
  • the inside of the rear end side loosely wound portion 22 of the coil spring 20 is filled with the cured resin 40 and the outer periphery of the rear end side loosely wound portion 22. Further, a resin layer 40A (cured resin layer covering the coil wire) is formed by the cured resin 40, and a hydrophilic resin coating layer 50 is laminated on the surface of the resin layer 40A.
  • the core wire 10 and the coil spring 20 are integrated, and the torque transmission performance of the guide wire is greatly improved.
  • the rotational torque transmitted from the 10 proximal end large diameter portions 14 is reliably transmitted to the distal end of the coil spring 20 integrated with the distal end small diameter portion 11.
  • a resin layer 40A is formed on the outer periphery of the rear end side loosely wound portion 22 of the coil spring 20, and a hydrophilic resin coating layer 50 is laminated on the surface of the resin layer 40A (rear end side loosely wound portion). 2 2), the hydrophilic resin coating layer 50 is formed on the outer periphery of the coil spring 20 via the resin layer 40A. Therefore, the hydrophilic resin coating layer 50 is firmly fixed to the coil spring 20, thereby The suitable lubricity due to can be expressed stably.
  • the inside of the rear end side sparsely wound portion 22 is filled, and the cured resin 40 constituting the resin layer 40A has a good adhesiveness to both the coil spring 20 and the hydrophilic resin.
  • a photo-curing resin such as urethane acrylate resin, polyurethane resin, silicone resin, epoxy resin, acrylic resin, and nylon resin, or a cured product of thermosetting resin.
  • the film thickness of the resin layer 40A covering the outer periphery of the rear end side loosely wound portion 22 is, for example, 1 to 100 ⁇ m, preferably 3 to 10 ⁇ m.
  • hydrophilic resin that constitutes the hydrophilic resin coating layer 50 that is laminated on the surface of the resin layer 40A
  • all conventionally known hydrophilic polymers that are used for hydrophilic treatment of medical devices can be used.
  • polysaccharides such as polyethylene glycol, polyethylene oxide, polyol, polyacrylamide, polyvinyl pyrrolidone, polyvinyl alcohol, polyether, polyurethane, polycarboxylic acid and derivatives thereof, cellulose, protein, hyaluronic acid can be exemplified.
  • these hydrophilic polymers may have a crosslinked structure.
  • the thickness of the hydrophilic resin layer 50 is, for example, 1 to 30 ⁇ m, preferably 3 to 19 ⁇ m.
  • the method of filling the cured resin 40 and forming the resin layer 40A and the method of forming the laminated layer of the hydrophilic resin 50 are not particularly limited.
  • the rear end side loosely wound portion attached to the core wire 10 is used. 22 is immersed in a curable resin to fill the inside of the rear end side loosely wound portion 22 with a curable resin, and a resin layer is formed on the surface of the rear end side loosely wound portion 22, which is thermoset.
  • a method may be mentioned in which a cured resin 40 (resin layer 40A) is obtained by photocuring, and then a hydrophilic resin is applied to the surface of the resin layer 40A by an appropriate means.
  • the outer periphery of the tip side densely wound part 21 is masked, etc. It is preferable to prevent inflow and adhesion of the curable resin to the inside or the outer periphery.
  • the outer periphery of the tip side densely wound portion 21 of the coil spring 20 is not covered with resin, and the constituent material of the coil spring 20 (X-ray opaque substance) Etc.) are exposed.
  • information in the blood vessel into which the guide wire 1 of the present embodiment is inserted for example, the state of a lesion site such as a stenosis part or an obstruction part
  • resistance (change) on the hand side for example, the state of a lesion site such as a stenosis part or an obstruction part
  • the guide wire 1 of the present embodiment can be reliably pushed toward the site.
  • the inside of the front end side tightly wound portion 21 is not filled with resin.
  • the flexibility and softness in the front end side densely wound portion 21 can be sufficiently secured, and the shaping operation can be easily performed in the front end side closely wound portion 21.
  • the torque transmission property of the guide wire 1 is improved by filling the inside of the rear end side loosely wound portion 22 with the cured resin 40. Sufficiently secured.
  • the length (L 2 ) of the coil spring 20 shown in FIG. 2 is preferably 51 to 800 mm, more preferably 85 to 310 mm, and 115 mm if a suitable example is shown.
  • the length (L 21 ) of the tip side densely wound portion 21 is preferably 1 to 50 mm, more preferably 20 to 40 mm, and 30 mm if a suitable example is shown.
  • the length (L 22 ) of the rear end side loosely wound portion 22 is preferably 50 to 750 mm, more preferably 65 to 270 mm, and 85 mm if a suitable example is shown.
  • the length (L 21 ) of the distal end side tightly wound portion 21 that is not coated with resin is too small, information in the blood vessel into which the guide wire is inserted cannot be sufficiently grasped, and the guide The distal end of the wire becomes slippery and it is difficult to push such a guidewire toward the target site.
  • the length (L 21 ) of the distal end side tightly wound portion 21 is excessive, the lubricity at the distal end portion of the guide wire is insufficient and, for example, it is difficult to pass through the stenosis site. For example, the insertion property of the guide wire is impaired.
  • the guide wire is Information in the inserted blood vessel cannot be fully grasped, and it is difficult to push the guide wire toward the target site.
  • the length (L 3 ) of the substantially hemispherical tip formed by the solder 31 is, for example, 0.1 to 5.0 mm, and 0.3 mm is a preferable example.
  • the distal end portion to which the coil spring 20 (rear end side loosely wound portion 22) is attached has good lubricity and enters the blood vessel. While the insertability of the coil spring 20 is good, the outer periphery of the distal end side densely wound portion 21 is not covered with resin, and the constituent material (metal) of the coil spring 20 is exposed, so that the information in the blood vessel is resisted (changed). ) Can be grasped sufficiently on the hand side, and can be reliably pushed toward the target site. Further, since the cured resin 40 is filled in the rear end side loosely wound portion 22, the torque transmission is excellent. In addition, since the inside of the distal end side tightly wound portion 21 is not filled with resin, the shaping operation can be easily performed.

Abstract

L'invention concerne un fil-guide médical qui a : un fil de noyau (10) ayant une section de petit diamètre d'extrémité distale (11) et une section de grand diamètre d'extrémité proximale (14); et un ressort enroulé (20) monté sur la périphérie externe de la section de petit diamètre d'extrémité distale (11). Le ressort enroulé (20) comprend : une section étroitement enroulée d'extrémité avant (21) ayant un pas qui est 1,0 à 1,8 fois le diamètre du fil de bobine; et une section lâchement enroulée d'extrémité arrière (22) ayant un pas qui est 1,8 à 2,5 fois le diamètre du fil de bobine. L'intérieur de la section lâchement enroulée d'extrémité arrière (22) est rempli d'une résine (40), et une couche de résine (40A) composée de la résine est formée sur la périphérie externe de la section lâchement enroulée d'extrémité arrière (22). Une couche de revêtement de résine hydrophile (50) est laminée et formée sur la surface de la couche de résine (40A). La périphérie externe de la section étroitement enroulée d'extrémité avant (21) n'est pas revêtue d'une résine, et un matériau qui forme le ressort enroulé (20) est exposé à la périphérie externe. Le fil-guide a des propriétés lubrifiantes satisfaisantes à son extrémité distale, peut être introduit de façon satisfaisante, permet à des informations à l'intérieur d'un vaisseau sanguin d'être suffisamment détectées comme résistance (changement) par une main de l'opérateur, et peut être avancé de façon fiable vers un site de destination.
PCT/JP2013/053077 2012-03-29 2013-02-08 Fil-guide médical WO2013145893A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201380004444.6A CN104023783B (zh) 2012-03-29 2013-02-08 医疗用导线
KR1020147026779A KR101844630B1 (ko) 2012-03-29 2013-02-08 의료용 가이드 와이어
HK15101141.9A HK1200746A1 (en) 2012-03-29 2015-02-03 Medical guide wire

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012-077045 2012-03-29
JP2012077045A JP5404840B2 (ja) 2012-03-29 2012-03-29 医療用ガイドワイヤ

Publications (1)

Publication Number Publication Date
WO2013145893A1 true WO2013145893A1 (fr) 2013-10-03

Family

ID=49259177

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2013/053077 WO2013145893A1 (fr) 2012-03-29 2013-02-08 Fil-guide médical

Country Status (6)

Country Link
JP (1) JP5404840B2 (fr)
KR (1) KR101844630B1 (fr)
CN (1) CN104023783B (fr)
HK (1) HK1200746A1 (fr)
TW (1) TWI517869B (fr)
WO (1) WO2013145893A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6793303B2 (ja) * 2015-11-17 2020-12-02 グンゼ株式会社 医療用ガイドワイヤ
DE102016009871A1 (de) * 2016-08-12 2018-02-15 Häberle Laser- und Feinwerktechnik GmbH & Co. KG Führungsdraht zum Einsatz in schlauchförmigen medizinischen Sonden, insbesondere zur Ernährungstherapie
KR102131490B1 (ko) * 2016-09-05 2020-07-07 아사히 인텍크 가부시키가이샤 가이드 와이어
EP3646808A4 (fr) * 2017-06-29 2021-01-13 Asahi Intecc Co., Ltd. Fil-guide à plasma
EP3747498A4 (fr) * 2018-02-01 2021-10-13 Asahi Intecc Co., Ltd. Fil-guide
KR20230144761A (ko) 2022-04-08 2023-10-17 성원메디칼 주식회사 의료용 마이크로 가이드 와이어

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5409470A (en) * 1993-05-07 1995-04-25 C. R. Bard, Inc. Dilatation catheter and guidewire with threaded tip connection
WO2009119386A1 (fr) * 2008-03-27 2009-10-01 テルモ株式会社 Fil-guide
EP2402051A1 (fr) * 2010-06-30 2012-01-04 PatentStra Co. Ltd. Fil-guide médical
WO2012009518A1 (fr) * 2010-07-16 2012-01-19 Neurointerventional Therapeutics, Inc. Système de fil-guide et cathéter et procédé de traitement d'un caillot de sang

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8777873B2 (en) 2008-06-13 2014-07-15 Cook Medical Technologies Llc Wire guide having a rib for coil attachment
KR101512541B1 (ko) * 2009-05-20 2015-04-15 니혼라이프라인 가부시키가이샤 의료용 가이드 와이어
JP5004256B2 (ja) * 2009-12-25 2012-08-22 朝日インテック株式会社 医療用ガイドワイヤ

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5409470A (en) * 1993-05-07 1995-04-25 C. R. Bard, Inc. Dilatation catheter and guidewire with threaded tip connection
WO2009119386A1 (fr) * 2008-03-27 2009-10-01 テルモ株式会社 Fil-guide
EP2402051A1 (fr) * 2010-06-30 2012-01-04 PatentStra Co. Ltd. Fil-guide médical
WO2012009518A1 (fr) * 2010-07-16 2012-01-19 Neurointerventional Therapeutics, Inc. Système de fil-guide et cathéter et procédé de traitement d'un caillot de sang

Also Published As

Publication number Publication date
TW201350154A (zh) 2013-12-16
HK1200746A1 (en) 2015-08-14
JP5404840B2 (ja) 2014-02-05
KR101844630B1 (ko) 2018-04-02
KR20140141605A (ko) 2014-12-10
CN104023783B (zh) 2016-01-20
CN104023783A (zh) 2014-09-03
TWI517869B (zh) 2016-01-21
JP2013202308A (ja) 2013-10-07

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