WO2013051889A3 - 한 번의 시료 주입으로 순차적인 반응 조건의 변화가 가능한 멤브레인 센서 - Google Patents

한 번의 시료 주입으로 순차적인 반응 조건의 변화가 가능한 멤브레인 센서 Download PDF

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Publication number
WO2013051889A3
WO2013051889A3 PCT/KR2012/008085 KR2012008085W WO2013051889A3 WO 2013051889 A3 WO2013051889 A3 WO 2013051889A3 KR 2012008085 W KR2012008085 W KR 2012008085W WO 2013051889 A3 WO2013051889 A3 WO 2013051889A3
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WIPO (PCT)
Prior art keywords
reaction
sample injection
single sample
membrane sensor
reaction condition
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Application number
PCT/KR2012/008085
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English (en)
French (fr)
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WO2013051889A2 (ko
Inventor
김민곤
정효암
안준형
Original Assignee
광주과학기술원
한국생명공학연구원
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Application filed by 광주과학기술원, 한국생명공학연구원 filed Critical 광주과학기술원
Priority to CN201280049502.2A priority Critical patent/CN103874924B/zh
Priority to US14/349,932 priority patent/US9857363B2/en
Priority to EP12837916.1A priority patent/EP2765422B1/en
Publication of WO2013051889A2 publication Critical patent/WO2013051889A2/ko
Publication of WO2013051889A3 publication Critical patent/WO2013051889A3/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

본 발명은 한번의 시료주입으로 반응 조건의 변화가 가능한 멤브레인 센서 및 이를 이용한 반응의 측정 방법에 관한 것으로, 보다 상세하게는, 반응물질 저장부와 반응 멤브레인 사이에 비대칭막을 형성시켜 두 가지 이상의 반응 조건을 갖는 생체 반응을 한 번의 시료 주입으로 순차적으로 일어나도록 설계한 멤브레인 센서에 관한 것이다.
PCT/KR2012/008085 2011-10-06 2012-10-05 한 번의 시료 주입으로 순차적인 반응 조건의 변화가 가능한 멤브레인 센서 WO2013051889A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN201280049502.2A CN103874924B (zh) 2011-10-06 2012-10-05 通过一次的试样注入就能够依次改变反应条件的膜传感器
US14/349,932 US9857363B2 (en) 2011-10-06 2012-10-05 Membrane sensor capable of sequentially changing reaction condition by single sample injection
EP12837916.1A EP2765422B1 (en) 2011-10-06 2012-10-05 Membrane sensor enabled with sequential change of reaction condition with single sample injection

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2011-0101670 2011-10-06
KR20110101670 2011-10-06
KR1020120110523A KR101394221B1 (ko) 2011-10-06 2012-10-05 한 번의 시료 주입으로 순차적인 반응 조건의 변화가 가능한 멤브레인 센서
KR10-2012-0110523 2012-10-05

Publications (2)

Publication Number Publication Date
WO2013051889A2 WO2013051889A2 (ko) 2013-04-11
WO2013051889A3 true WO2013051889A3 (ko) 2013-07-04

Family

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Application Number Title Priority Date Filing Date
PCT/KR2012/008085 WO2013051889A2 (ko) 2011-10-06 2012-10-05 한 번의 시료 주입으로 순차적인 반응 조건의 변화가 가능한 멤브레인 센서

Country Status (5)

Country Link
US (1) US9857363B2 (ko)
EP (1) EP2765422B1 (ko)
KR (1) KR101394221B1 (ko)
CN (1) CN103874924B (ko)
WO (1) WO2013051889A2 (ko)

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CN106796220A (zh) * 2015-03-11 2017-05-31 株式会社认知生物 膜传感器的制造方法
WO2017040820A1 (en) * 2015-09-01 2017-03-09 Polymer Technology Systems, Inc. Systems and methods for reagentless test strips
KR101788221B1 (ko) * 2015-12-29 2017-10-19 광주과학기술원 팽창재를 이용한 멤브레인 스트립 센서
PT3417075T (pt) * 2016-02-15 2021-01-28 Empe Diagnostics Ab Dispositivo de diagnóstico e método relacionado
KR101854240B1 (ko) * 2016-05-18 2018-06-14 광주과학기술원 후크 효과가 없는 면역크로마토그래피 스트립 센서
KR102015360B1 (ko) * 2017-01-10 2019-08-28 광주과학기술원 측방 유동 분석에서의 신호 증폭 키트 및 그의 제작 방법
KR101985415B1 (ko) * 2017-04-06 2019-06-03 광주과학기술원 팽창형 구조체 및 이를 이용한 스트립 센서
KR101998948B1 (ko) * 2017-05-29 2019-07-11 주식회사 포스코 수용성 코팅층을 이용한 측방유동 분석에서의 신호 증폭 방법 및 이를 이용한 측방유동 분석 장치
KR101854600B1 (ko) 2017-09-19 2018-05-04 (주)텔트론 다채널 독소 측정 스트립 및 이를 포함하는 다채널 독소 측정 장치
KR102153736B1 (ko) * 2018-09-12 2020-09-08 울산과학기술원 수직 유체 흐름을 갖는 바이오 센서 및 이를 이용한 분석 방법
WO2020084620A1 (en) * 2018-10-25 2020-04-30 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Means and method for point-of-care analysis of liquid samples
KR102261186B1 (ko) * 2019-06-28 2021-06-07 주식회사 지엠디바이오텍 자동신호증폭이 가능한 측방유동면역센서

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Also Published As

Publication number Publication date
CN103874924B (zh) 2016-01-06
US9857363B2 (en) 2018-01-02
EP2765422B1 (en) 2017-07-26
EP2765422A4 (en) 2015-06-17
US20140255958A1 (en) 2014-09-11
WO2013051889A2 (ko) 2013-04-11
KR101394221B1 (ko) 2014-05-14
KR20130037647A (ko) 2013-04-16
EP2765422A2 (en) 2014-08-13
CN103874924A (zh) 2014-06-18

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