WO2013041696A1 - Spray nasal et gouttes nasales ayant un effet stimulant et tonifiant - Google Patents

Spray nasal et gouttes nasales ayant un effet stimulant et tonifiant Download PDF

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Publication number
WO2013041696A1
WO2013041696A1 PCT/EP2012/068688 EP2012068688W WO2013041696A1 WO 2013041696 A1 WO2013041696 A1 WO 2013041696A1 EP 2012068688 W EP2012068688 W EP 2012068688W WO 2013041696 A1 WO2013041696 A1 WO 2013041696A1
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WO
WIPO (PCT)
Prior art keywords
oil
composition
use according
nasal
extracts
Prior art date
Application number
PCT/EP2012/068688
Other languages
German (de)
English (en)
Inventor
Hyeck-Hee Lee
Ute Steinfeld
Frank Holzer
Original Assignee
F. Holzer Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Holzer Gmbh filed Critical F. Holzer Gmbh
Publication of WO2013041696A1 publication Critical patent/WO2013041696A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne l'utilisation d'une composition qui contient au moins une huile essentielle ainsi qu'au moins une substance à effet stimulant et qui est destinée à une application nasale. A cet effet, ladite composition est introduite dans le nez et elle est plus particulièrement formulée sous forme de spray nasal ou de gouttes nasales mais convient également pour l'inhalation.
PCT/EP2012/068688 2011-09-21 2012-09-21 Spray nasal et gouttes nasales ayant un effet stimulant et tonifiant WO2013041696A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102011114094.1 2011-09-21
DE102011114094A DE102011114094A1 (de) 2011-09-21 2011-09-21 Stimulierendes und belebendes Nasenspray und Nasentropfen

Publications (1)

Publication Number Publication Date
WO2013041696A1 true WO2013041696A1 (fr) 2013-03-28

Family

ID=46924430

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2012/068688 WO2013041696A1 (fr) 2011-09-21 2012-09-21 Spray nasal et gouttes nasales ayant un effet stimulant et tonifiant

Country Status (2)

Country Link
DE (1) DE102011114094A1 (fr)
WO (1) WO2013041696A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014176449A1 (fr) * 2013-04-25 2014-10-30 Rinsenergy LLC Composition de rinçage buccal et procédé d'administration de compléments énergétiques

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020141184A1 (fr) * 2018-12-31 2020-07-09 Philip Morris Products S.A. Formulation de nicotine liquide à faible viscosité
EP3991573A1 (fr) * 2020-11-03 2022-05-04 Patrick Faber Compositions a administrer par le nez

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0640906A (ja) 1992-07-22 1994-02-15 Suntory Ltd 眠気抑制剤
WO1996000071A1 (fr) * 1994-06-23 1996-01-04 The Procter & Gamble Company Traitement du besoin de nicotine et/ou des symptomes de manque du fumeur au moyen d'une composition liquide contenant de la nicotine et de la cafeine ou de la xanthine, pour administration par voie nasale
US6350458B1 (en) * 1998-02-10 2002-02-26 Generex Pharmaceuticals Incorporated Mixed micellar drug deliver system and method of preparation
EP1199073A1 (fr) * 1999-07-02 2002-04-24 Nippon Chemical Works Co., Ltd Preparation contenant un acide aminoethane sulfonique
EP1346726A1 (fr) 2000-12-25 2003-09-24 Shiseido Company, Ltd. Composition de parfum stimulant le systeme sympathique
WO2006060505A2 (fr) * 2004-12-01 2006-06-08 Dacanay Rhodel G Complement nutritionnel a base de capsaicine
WO2006066500A1 (fr) * 2004-12-20 2006-06-29 Peixue Ling Procédé de synthèse de dérivés de quinazoline et application à la fabrication d'un médicament pour le traitement d'une maladie de type tumoral
EP1808159A1 (fr) * 2005-12-23 2007-07-18 Les Laboratoires Servier Nouvelle composition pharmaceutique à base d'huile essentielle pour pulverisation nasale et/ou buccale
WO2009001085A2 (fr) * 2007-06-25 2008-12-31 Kind Consumer Limited Composition inhalable
DE202008016517U1 (de) * 2008-12-12 2009-03-05 Ratiopharm Gmbh Wässrige Zusammensetzung enthaltend Dexpanthenol und Natriumchlorid
US20090069433A1 (en) * 2007-09-10 2009-03-12 Wayne Jeffrey Perry Nasal rinse additive
US20110053988A1 (en) * 2009-08-29 2011-03-03 Jorge Alberto Cassara Low-dose, non-irritating nicotine nasal composition to reduce the desire to smoke

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2507445B2 (ja) 1987-06-23 1996-06-12 住友電気工業株式会社 光コネクタコ−ドの製造方法
JP2003128583A (ja) * 2001-08-15 2003-05-08 Rohto Pharmaceut Co Ltd 清涼化組成物
US20060120967A1 (en) * 2004-12-07 2006-06-08 Qpharma, Llc Solution forms of cyclodextrins for nasal or throat delivery of essential oils
DE202007007584U1 (de) * 2007-05-29 2007-08-02 Day-Med-Concept Gmbh Flüssigformulierung enthaltend fettlösliche Verbindungen als Solubilisat
DE202010012255U1 (de) * 2010-09-07 2010-11-18 Krewel Meuselbach Gmbh Nasenspray

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0640906A (ja) 1992-07-22 1994-02-15 Suntory Ltd 眠気抑制剤
WO1996000071A1 (fr) * 1994-06-23 1996-01-04 The Procter & Gamble Company Traitement du besoin de nicotine et/ou des symptomes de manque du fumeur au moyen d'une composition liquide contenant de la nicotine et de la cafeine ou de la xanthine, pour administration par voie nasale
US6350458B1 (en) * 1998-02-10 2002-02-26 Generex Pharmaceuticals Incorporated Mixed micellar drug deliver system and method of preparation
EP1199073A1 (fr) * 1999-07-02 2002-04-24 Nippon Chemical Works Co., Ltd Preparation contenant un acide aminoethane sulfonique
EP1346726A1 (fr) 2000-12-25 2003-09-24 Shiseido Company, Ltd. Composition de parfum stimulant le systeme sympathique
WO2006060505A2 (fr) * 2004-12-01 2006-06-08 Dacanay Rhodel G Complement nutritionnel a base de capsaicine
WO2006066500A1 (fr) * 2004-12-20 2006-06-29 Peixue Ling Procédé de synthèse de dérivés de quinazoline et application à la fabrication d'un médicament pour le traitement d'une maladie de type tumoral
EP1808159A1 (fr) * 2005-12-23 2007-07-18 Les Laboratoires Servier Nouvelle composition pharmaceutique à base d'huile essentielle pour pulverisation nasale et/ou buccale
WO2009001085A2 (fr) * 2007-06-25 2008-12-31 Kind Consumer Limited Composition inhalable
US20090069433A1 (en) * 2007-09-10 2009-03-12 Wayne Jeffrey Perry Nasal rinse additive
DE202008016517U1 (de) * 2008-12-12 2009-03-05 Ratiopharm Gmbh Wässrige Zusammensetzung enthaltend Dexpanthenol und Natriumchlorid
US20110053988A1 (en) * 2009-08-29 2011-03-03 Jorge Alberto Cassara Low-dose, non-irritating nicotine nasal composition to reduce the desire to smoke

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014176449A1 (fr) * 2013-04-25 2014-10-30 Rinsenergy LLC Composition de rinçage buccal et procédé d'administration de compléments énergétiques

Also Published As

Publication number Publication date
DE102011114094A8 (de) 2013-06-06
DE102011114094A1 (de) 2013-03-21

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