WO2012176562A1 - Sonde - Google Patents

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Publication number
WO2012176562A1
WO2012176562A1 PCT/JP2012/062495 JP2012062495W WO2012176562A1 WO 2012176562 A1 WO2012176562 A1 WO 2012176562A1 JP 2012062495 W JP2012062495 W JP 2012062495W WO 2012176562 A1 WO2012176562 A1 WO 2012176562A1
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WO
WIPO (PCT)
Prior art keywords
probe
optical fiber
light
tip
illumination
Prior art date
Application number
PCT/JP2012/062495
Other languages
English (en)
Japanese (ja)
Inventor
藤原　勝巳
桂田　弘之
岩坂　喜久男
夏野　靖幸
新　勇一
大澤　聡
純一 城野
Original Assignee
コニカミノルタアドバンストレイヤー株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by コニカミノルタアドバンストレイヤー株式会社 filed Critical コニカミノルタアドバンストレイヤー株式会社
Priority to JP2013521502A priority Critical patent/JP5928461B2/ja
Publication of WO2012176562A1 publication Critical patent/WO2012176562A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/07—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064—Constructional details of the endoscope body
    • A61B1/00071—Insertion part of the endoscope body
    • A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00096—Optical elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0615—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements for radial illumination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0623—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements for off-axis illumination

Definitions

  • the present invention relates to a probe including an optical system that irradiates a measurement target region of a living tissue with irradiation light and receives radiation emitted from the measurement target region due to the irradiation light.
  • the forceps channel is a tunnel-like path formed inside the endoscope from the proximal end to the distal end of the endoscope through which a treatment instrument such as a forceps or a capture net is passed. It is also called a work channel, an insertion channel, etc. (a channel may be described as a channel).
  • a tunnel-like path formed in the endoscope from the proximal end to the distal end of the endoscope is referred to as an endoscope channel.
  • Oral type endoscopes have an outer diameter of about 10 mm, and are often provided with an endoscope channel of less than 3 mm.
  • a conventional endoscope can be used and a relatively gentle curve is drawn to reach the body lumen.
  • flexibility like a mirror is not required, it is necessary to have a very small outer diameter that passes through the endoscope channel, so that depending on the configuration mounted on the probe, the structure tends to be very precise.
  • the number of parts increases, There is a strong demand for avoiding complicated and large probe structures.
  • an endoscope is a direct-viewing type that images its traveling direction. For example, when the probe is a side-view type that observes the side perpendicular to the direction of travel of the endoscope, the measurement target part of the probe deviates from the endoscope's field of view.
  • the operation of the endoscope main body and the special diagnostic apparatus may be complicated, and as a result, the examination time may be lengthened and the burden on the patient's body may be increased.
  • Patent Document 1 discloses a third optical fiber that guides light for visual recognition around a first optical fiber for irradiating excitation light and a second optical fiber for receiving light from a tissue. And a ring-shaped member provided on the distal end side of the third optical fiber around the first and second optical fibers, and a light-reflecting film attached to the ring-shaped member by the light guided by the third optical fiber.
  • a probe is described that attempts to improve visibility by reflecting and radiating to the outer periphery.
  • the probe tip and the measurement target part of the biological tissue are kept at a preferable constant distance during measurement, and the measurement target part has a load that affects the measurement. It is also desirable not to add.
  • the probe described in Patent Document 1 is supposed to have a substantially flat probe tip in close contact with a measurement site during measurement, and such non-contact measurement is difficult.
  • FIG. 9 of Patent Document 2 is an optical diagnostic apparatus for observing a tissue by scanning a laser beam guided by an optical fiber, and an annular cap arranged at the tip of a probe is an object to be observed. An optical diagnostic device is described which is pressed against a tissue for observation.
  • Patent Document 2 does not describe performing illumination before observation, and does not describe inserting or removing the probe into the endoscope channel.
  • the present invention has been made in view of the above-described problems in the prior art, and avoids complication and enlargement of the structure of the probe while avoiding as much as possible the load on the measurement target site of the living tissue. It is an object of the present invention to provide a probe that can smoothly perform accurate measurement.
  • the invention according to claim 1 for solving the above-described problems is directed to the proximal end side by receiving irradiation light for measurement from the distal end portion toward the measurement target portion and receiving the emitted light emitted from the measurement target portion.
  • An optical fiber for illumination that guides illumination light; and
  • the probe includes a positioning unit that contacts the living tissue around the measurement target part without contacting the measurement target part and positions a probe tip with respect to the measurement target part.
  • the tip member is formed with a hole opening in the tip surface within a range including the irradiation range of the irradiation light in a plane including the tip surface of the tip member. It is a probe as described in.
  • the invention according to claim 3 is the probe according to claim 2, wherein a distal end surface of a portion formed around the hole of the distal end member abuts on the living tissue.
  • the invention according to claim 4 is the probe according to claim 3, wherein the tip member is formed in a cylindrical shape forming a peripheral wall around the hole.
  • the invention according to claim 5 is the probe according to claim 4, wherein the peripheral wall is formed with the same thickness in the probe axial direction.
  • the invention according to claim 6 is the probe according to claim 4, wherein the peripheral wall is formed in an inner taper shape so as to increase the diameter of the hole portion toward the tip in the probe axial direction.
  • the invention according to claim 7 is the probe according to any one of claims 1 to 6, wherein an edge portion of a distal end surface of the distal end member contacting the living tissue is rounded.
  • a measurement optical system for guiding the irradiation light and the radiated light behind the distal end surface of the distal end member in contact with the living tissue in the probe axial direction. It is a probe as described in any one of Claim 7.
  • the emission end of the illumination optical fiber contacts the inner peripheral surface of the tip member toward the outer side in the probe radial direction, so that the position of the emission end in the probe radial direction is changed.
  • the position of the emission end in the probe axis direction is fixed by the emission end of the illumination optical fiber contacting the rearward surface of the tip member toward the probe axis direction tip.
  • a holding groove extending in the probe axis direction is formed on the inner peripheral surface of the rear end portion of the tip member, and the emission end portion of the illumination optical fiber is fitted into the holding groove.
  • the invention according to claim 12 is the probe according to claim 11, wherein the rear end of the holding groove in the probe axial direction is opened in a state before the illumination optical fiber is arranged.
  • the invention described in claim 13 is provided with a holder connected to the rear end of the tip member and holding the irradiation optical fiber, the light receiving optical fiber, and the illumination optical fiber. It is a probe as described in.
  • the invention according to claim 14 is the probe according to claim 13, wherein the tip member and the holder are positioned in the probe axial direction by bringing the rear end of the tip member into contact with the holder.
  • the invention according to claim 15 is the probe according to any one of claims 1 to 14, wherein the tip member diffuses the irradiation light.
  • the invention according to claim 16 is the probe according to any one of claims 1 to 15, wherein a tip of the illumination optical fiber is disposed closer to a probe tip than a rear end of the tip member. .
  • the length of the positioning portion in the optical axis direction is set so that the focal point of the optical system is formed in a predetermined region including the surface with which the positioning portion abuts.
  • the position of the probe can be accurately grasped by illuminating the living tissue with the illumination light guided by the illumination optical fiber and radiated through the tip member.
  • the tip member can contact the living tissue around the measurement target part without contacting the measurement target part and the probe tip can be positioned with respect to the measurement target part, the measurement target is in a state where the illumination is turned on. It is possible to accurately observe the part as it is. Furthermore, it is easy to maintain the positioned state even when the illumination is turned off, and accurate measurement can be smoothly performed in a state where the load on the measurement target portion of the living tissue is avoided as much as possible.
  • the tip member for positioning constitutes a part of the illumination means, the number of parts does not increase, and illumination is performed through the tip member, which may increase the complexity and size of the probe. It can be avoided.
  • the probe 1 of the present embodiment is used by being inserted into an endoscope channel 101 formed in the endoscope 100.
  • An imaging window 102 and an illumination window 103 are provided on the distal end surface of the endoscope 100. That is, the endoscope 100 includes an endoscope camera for photographing the inside of the living body from the photographing window 102 and an illumination device for illuminating the photographing target from the illumination window 103.
  • the probe 1 is inserted into the endoscope channel 101 and guided into the body, and optical measurement is performed by the probe 1.
  • the illumination device of the endoscope 100 is turned off and emitted from the probe 1 at least before the endoscope is inserted into the living body and the tip of the endoscope reaches the vicinity of the measurement target site Illuminate the body with illumination light i. Then, the probe 1 is accurately positioned at the measurement target site by photographing with the endoscope using the illumination light from the probe 1. As shown in FIG. 1B, the base end of the probe 1 is connected to the base unit 2 of the probe system.
  • the probe 1 is configured by connecting the tip member 10, the holder 20, and the outer tube 30 shown in FIG. 2 in this order.
  • FIG. 3 shows details of the tip member 10
  • FIG. 4 shows details of the holder 20. Details of these members will be described later.
  • the probe 1 is caused by the irradiation light L1 from the irradiation optical fiber 41 for guiding the irradiation light for measurement and the measurement target portion 3a of the living tissue 3 irradiated with the irradiation light L1.
  • a light receiving optical fiber 42 that receives the emitted radiated light L2 and guides it to the proximal end side of the probe 1, an illumination optical fiber 43 that guides illumination light, a lens 44, and a ferrule 45. ing.
  • the irradiation optical fiber 41 and the light receiving optical fiber 42 are fixed to the ferrule 45, and the ferrule 45 is inserted into the rear end portion of the holder 20 and fixed to the holder 20.
  • the lens 44 is fixed inside the front end member 10, and the front end portion of the holder 20 is inserted and fixed to the rear end portion of the front end member 10.
  • the center axis of the emission end of the irradiation optical fiber 41 and the center axis of the light receiving end of the light receiving optical fiber 42 with respect to the optical axis of the lens 44 are positioned.
  • the base unit 2 includes a light source device 2a for irradiation light incident on the irradiation optical fiber 41, a light detector 2b for detecting light guided by the light receiving optical fiber 42, a light source device 2c for illumination light, and a control for controlling them.
  • a device 2d and the like are provided.
  • the control device 2d includes an operation unit for receiving a measurement execution instruction from the user, and controls each unit based on the instruction.
  • Irradiation light emitted from the light source device 2a and guided by the irradiation optical fiber 41 is irradiated to the measurement target portion 3a of the living tissue 3 through the lens 44, and is emitted from the measurement target portion 3a due to the irradiation light.
  • the condensed light is collected by the lens 44 and is incident on the light receiving optical fiber 42.
  • the light is guided to the proximal end side of the probe 1 by the light receiving optical fiber 42 and introduced into the photodetector 2 b of the base unit 2.
  • the control device 2d of the base unit 2 controls the illumination light source device 2c to turn off the illumination, and the measurement illumination light source device 2a. Then, the photodetector 2b is controlled to receive the radiated light from the living tissue 3 as described above and cause the photodetector 2b to output the detection result. At the end of the detection, the control device 2d controls the illumination light source device 2c to turn on the illumination again.
  • the photodetector detects the light intensity, spectral characteristics, polarization characteristics, and the like of the light input through the light receiving optical fiber 42, and outputs the detection result to the measurement calculation unit of the control device 2d.
  • the measurement calculation unit of the control device 2d analyzes the detection result and specifies information useful for diagnosing the lesion state of the living tissue 3.
  • excitation light is generated by the light source device 2a for measurement irradiation light.
  • fluorescence is generated by the excitation light at the measurement target site 3a irradiated with the excitation light.
  • the emitted light from the measurement target portion 3a including the fluorescence and the reflected light enters the light receiving optical fiber 42 and is input to the photodetector 2b.
  • Fluorescence is broadly defined as an object irradiated with X-rays, ultraviolet rays, or visible light absorbs its energy, excites electrons, and releases excess energy as electromagnetic waves when it returns to the ground state. To do.
  • the photodetector 2b disperses the return light, and the measurement calculation unit analyzes the spectral distribution to identify and detect the amount of fluorescence. Detect the lesion status of the subject.
  • the distal end portion of the probe 1 with respect to the measurement target portion 3a will be described.
  • This positioning is performed by bringing the distal end surface of the distal end member 10 into contact with the living tissue 3.
  • the distal end surface of the distal end member 10 contacts the living tissue 3 around the measurement target portion 3a without contacting the measurement target portion 3a.
  • the tip member 10 is formed with a hole 12 that opens to the tip surface 11 in a range including the irradiation range of the irradiation light L1 on a plane including the tip surface 11 of the tip member 10.
  • the cylindrical part of the tip member 10 surrounding the hole 12 and the tip surface 11 constitute a positioning part.
  • the contact with the living tissue is preferably performed entirely around the hole 12 so as not to damage the living tissue.
  • the tip member 10 is an optical member that emits illumination light, and is an antifouling member that protects the optical component (the lens 44 in this embodiment) that first appears in the hole 12 when viewed from the tip side from dirt. Function. Therefore, the tip member 10 is formed in a cylindrical shape that constitutes the peripheral wall 13 around the hole 12.
  • the front end surface 11 of the member (circumferential wall 13) comprised in the circumference
  • An optical system (in this embodiment, an irradiation optical fiber 41, a light receiving optical fiber 42, and a lens 44) is disposed. Accordingly, a cavity is secured from the opening at the tip of the hole 12 to the predetermined position, and the probe 1 is not configured with a portion that contacts the measurement target portion 3a.
  • the distance from the front surface position of the lens 44 to the surface including the distal end surface 11 of the distal end member 10, that is, the length of the peripheral wall 13 in the probe axial direction is the surface where the focal point of the lens includes the distal end surface 11 or the probe on this surface. It is set so as to be connected to a neighboring position in the axial direction. Therefore, by bringing the distal end surface 11 into contact with the living tissue, the lens is positioned in the optical axis direction, and the lens is focused on a predetermined region in the optical axis direction including the surface with which the distal end surface 11 abuts. . Thereby, the front-end
  • the peripheral wall 13 is formed with the same thickness in the probe axial direction. With the same thickness, the pressure at the time of contact with the living tissue 3 can be relieved without narrowing the distal end surface 11.
  • the peripheral wall 13a may be formed in an inner tapered shape so that the diameter of the hole 12a increases toward the tip in the probe axial direction. With this configuration, the peripheral wall 13a is moved away from the optical paths of the irradiation light L1 and the radiated light L2, and stray light due to interference with the peripheral wall 13a can be prevented, thereby ensuring measurement accuracy. It is also effective to make the irradiation range of the irradiation light L1 larger than the outer diameter of the probe.
  • the corner of the edge portion (particularly the outer edge portion) of the tip surface 11 that comes into contact with the living tissue 3 of the tip member 10 is rounded. It has been. If there is no roundness, when the corner of the tip member 10b comes into contact with the living tissue 3, the pressing force concentrates and the living tissue 3 may be damaged and damaged. Therefore, as shown in FIG. It is desirable to disperse the pressing force at the time of contact.
  • the illumination optical fiber 43 is provided in the probe 1.
  • An irradiation optical fiber 41 and a light receiving optical fiber 42 are arranged at the center of the probe, and a plurality of illumination optical fibers 43 are arranged around it.
  • the emission end of the illumination optical fiber 43 is disposed closer to the distal end side of the probe 1 than the rear end of the distal end member 10.
  • the exit end of the illumination optical fiber 43 is inserted from the rear end of the holder 20 and protrudes obliquely outward from the front end of the holder 20 toward the front end in the probe axial direction.
  • FIG. 4 shows details of the guide section.
  • a guide unit is provided for each of the illumination optical fibers 43.
  • One guide portion includes a fiber insertion hole 21 and a tapered groove 22.
  • the holder 20 in the present embodiment has a configuration in which seven illumination optical fibers 43 are arranged around the holder 20.
  • the tapered groove 22 is continuous to the tip end in the probe axial direction with respect to the fiber insertion hole 21, and the inner surface of the tapered groove 22 is tapered so as to move outward in the probe radial direction toward the tip end in the probe axial direction. Is formed. Therefore, the exit end portion of the illumination optical fiber 43 that extends through the fiber insertion hole 21 to the tip end in the probe axis direction is guided so as to protrude obliquely outward toward the tip end in the probe axis direction.
  • a holding groove 17 extending in the probe axis direction is formed on the inner peripheral surface of the rear end portion of the tip member 10.
  • a lens arrangement hole 15 and a holder insertion hole 16 are formed in the distal end member 10 continuously from the above-described hole portion 12.
  • the holding groove 17 is formed on the inner peripheral surface of the holder insertion hole 16.
  • the holding grooves 17 are formed at the number and position facing the tapered grooves 22 on a one-to-one basis.
  • the rear end of the holding groove 17 in the probe axis direction is opened before the illumination optical fiber is attached, and the exit end of the illumination optical fiber 43 extending from the holder 20 can be easily inserted from the rear.
  • the tip member 10 when the tip member 10 is molded, a molding die for molding the holder insertion hole 16 and the holding groove 17 can be pulled out rearward, which is convenient for molding.
  • the front end of the holding groove 17 in the probe axial direction is constituted by a front end side wall surface 17a (see FIG. 3), and the direction thereof is toward the rear end of the probe 1.
  • the exit end of the illumination optical fiber 43 must be accurately positioned with respect to the distal end member 10 that is the final light emitting portion of the illumination light i.
  • the probe radius of the emission end is firstly brought into contact with the inner peripheral surface of the tip member 10 with the emission end of the illumination optical fiber 43 protruding from the holder 20 facing outward in the probe radius direction. The position in the direction is fixed.
  • the inner peripheral surface corresponds to the substantially semi-cylindrical inner bottom surface of the holding groove 17.
  • the exit end of the illumination optical fiber 43 abuts on the rear surface of the tip member 10 toward the tip in the probe axis direction, so that the position of the exit end in the probe axis direction is fixed.
  • This rearward surface corresponds to the tip side wall surface 17a of the holding groove 17 in this embodiment.
  • this back surface may be diagonal.
  • the exit end of the illumination optical fiber 43 is fitted into the holding groove 17 so that the position of the exit end in the probe circumferential direction is fixed.
  • the positions of the emission end of the illumination optical fiber 43 in all directions relative to the tip member 10 are fixed at desired positions, and the plurality of illumination optical fibers 43 are arranged around the probe axis. It can be fixed in a desired arrangement, such as evenly distributed arrangement. Thus, the illuminance distribution of the illumination light i radiated from the probe 1 is made uniform.
  • a typical measurement procedure in this embodiment will be described. First, the endoscope is inserted into the human body with the illumination of the probe 1 inserted into the endoscope channel turned on. Then, the endoscope is moved closer to the measurement target part while viewing the image photographed by the photographing device of the endoscope 100.
  • the probe 1 When approaching the measurement target region, the probe 1 is protruded from the endoscope 100 to approach the measurement target region, and the distal end surface 11 of the probe 1 is pressed around the measurement target region.
  • the user operates the base unit 2 to instruct the start of measurement.
  • the control device 2d automatically executes turning off the illumination provided to the probe 1, measurement by the probe 1, and turning on the illumination. Repeat the probe illumination off / measurement / illumination measurement to measure the required location. In addition, you may make it use the illumination of the endoscope 100 until the stage before the process of pressing the probe 1 against a measurement object site
  • the position of the probe can be accurately grasped by illuminating the living tissue with the illumination light guided by the illumination optical fiber and emitted through the tip member 10. Further, the tip member 10 can contact the living tissue around the measurement target part without contacting the measurement target part, and can position the tip part of the probe 1 with respect to the measurement target part. Thus, it is possible to accurately observe the measurement target portion as it is. Furthermore, it is easy to maintain the positioned state even when the illumination is turned off, and accurate measurement can be smoothly performed in a state where the load on the measurement target portion of the living tissue is avoided as much as possible.
  • the tip member for positioning constitutes a part of the illumination means, the number of parts does not increase, and illumination is performed through the tip member, which may increase the complexity and size of the probe. It can be avoided. Furthermore, since illumination is provided on the probe, it is only necessary to control the illumination of the probe and irradiation light at the time of measurement by the probe, and it is not necessary to operate the illumination of an endoscope separate from the probe. By providing the function of automatically turning off the illumination of the probe in conjunction with the measurement of the probe, the complexity of the illumination operation can be further reduced.
  • a solid-state light emitting element such as an LED or an organic EL element
  • the present embodiment is advantageous also in the assembly stage for obtaining the fixed state as described above.
  • the tip member 10 and the holder 20 are connected and fixed, the emission end portions of all the illumination optical fibers 43 are moved from the holder 20 beyond the position regulated by the holding groove 17 of the emission end portion of the illumination optical fiber 43.
  • the position can be reliably regulated by the holding groove 17 so that the emission end portion is reversed.
  • it is possible to efficiently prevent assembly defects such as a gap between the front end side wall surface 17a of the holding groove 17 and the illumination optical fiber 43.
  • the tip member 10 and the holder 20 are connected and fixed by fitting the convex portion 23 shown in FIG. 4 to the rear end portion of the holding groove 17.
  • the convex portions 23 are respectively disposed rearward in the tapered groove 22, have a cylindrical surface corresponding to the inner bottom surface of the holding groove 17, and are formed up to the rear flange 24. Accordingly, when each convex portion 23 is fitted in each holding groove 17 and the rear end of the tip member 10 abuts against the flange 24, at least the positions of the tip member 10 and the holder 20 in the probe axial direction are determined with high accuracy. .
  • connection angle between them that is, the angle formed between the axial direction of the tip member 10 and the axial direction of the holder 20 is also determined with high accuracy, and in the present embodiment, they are substantially matched. Thereby, the axial distance and other positional relationships between the irradiation optical fiber 41 and the light receiving optical fiber 42 and the lens 44 are also determined with high accuracy.
  • An adhesive is applied between the tip member 10 and the holder 20 and fixed. By forming the convex part 23, the contact area of the tip member 10 and the holder 20 increases, and the joining strength by adhesion
  • the holder 20 and the outer tube 30 are fixed by press-fitting the tube connecting portion 25 behind the flange 24 into the outer tube 30.
  • An adhesive may be applied to this fixing.
  • the exit end of the illumination optical fiber 43 is disposed behind the peripheral wall 13 with its axial direction slightly diagonally outward toward the probe axial end.
  • the illumination light i emitted from the emission end of the illumination optical fiber 43 enters the tip member 10 and exits from the tip member 10.
  • the tip member 10 transmits the illumination light i and radiates it to a predetermined range including the tip in the probe axial direction.
  • the illumination light i is diffused by the tip member 10 so that the radiation range of the illumination light i, that is, the imaging range of the endoscope camera is sufficiently covered by the illumination range.
  • a circumferential groove 18 a is formed on the outer peripheral surface of the tip member 10 from which the illumination light i is emitted, and diffuses the illumination light i when emitted from the tip member 10.
  • a recess 18 b is formed on the outer peripheral surface of the tip member 10 from which the illumination light i is emitted, and diffuses the illumination light i when emitted from the tip member 10.
  • a rough surface 18 c is formed on the outer peripheral surface of the tip member 10 from which the illumination light i is emitted, and diffuses the illumination light i when emitted from the tip member 10.
  • the rough surface 18c has a roughened surface so as to diffuse light.
  • the rough surface 18 c may also be formed on the tip surface 11.
  • a rough surface 18 d is formed on the inner surface of the tip member 10 on which the illumination light i is incident, and the illumination light i is diffused when entering the tip member 10.
  • the rough surface 18d has a roughened surface so as to diffuse light.
  • the irregular reflection member 18e is disposed in the portion of the tip member 10 where the illumination light i is incident. When the illumination light i passes through the irregular reflection member 18e, the illumination light i is transmitted by the irregular reflection member 18e. Spread.
  • the irregular reflection member 18e one or a plurality of small pieces such as a fibrous material and a granular material are applied. Examples of the material of the irregular reflection member 18e include metal, glass, and resin.
  • the circumferential groove 18a, the recess 18b, and the rough surfaces 18c and 18d can be formed simultaneously with the resin molding of the tip member 10.
  • the rough surfaces 18c and 18d are formed by transferring the surface of the molding die on which minute irregularities are formed. Productivity is improved by processing at the same time.
  • Enlarging the radiation range of the illumination light i can also be achieved by processing the exit end of the illumination optical fiber 43.
  • the exit end 19a of the illumination optical fiber 43 is expanded in diameter by heat melting or the like, and the exit range of the illumination light i is expanded from the exit end 19a.
  • the emission end face 19b of the illumination optical fiber 43 is recessed in a mortar shape, and the emission angle of the illumination light i is enlarged.
  • scratches that cause leakage of the illumination light i are processed in the outer peripheral coating 19 c at the exit end of the illumination optical fiber 43, and from the outer periphery of the exit end of the illumination optical fiber 43.
  • the illumination light i is emitted, and the emission range of the illumination light i is expanded.
  • the coating end 19d of the emission end portion 19d of the illumination optical fiber 43 is peeled off, and the illumination light i is emitted from the outer peripheral portion of the emission end portion 19d of the illumination optical fiber 43.
  • the emission range of the illumination light i is expanded.
  • the inner surface of the tip member 10 In order to increase the illuminance to the side of the tip member 10, it is effective to configure the inner surface of the tip member 10 to be reflective.
  • a reflection film 19 f made of an aluminum metal film or the like is provided on the inner peripheral surface of the hole portion 12 and the lens arrangement hole 15 of the tip member 10 to form a mirror surface.
  • the illumination light directed toward the hole 12 or the lens arrangement hole 15 is reflected outward.
  • the inner peripheral surfaces of the hole 12 and the lens arrangement hole 15 are configured to be reflective to light coming from the outside. However, the situation is different for light coming from the inside. A part of the irradiation light L 1 emitted from the irradiation optical fiber 41 is reflected by the surface of the lens 44.
  • the light reaching the inner peripheral surfaces of the hole 12 and the lens arrangement hole 15 is absorbed or diffused on this surface so that the rate of incidence on the light receiving optical fiber 42 is reduced. That is, it is preferable that the inner peripheral surfaces of the hole 12 and the lens arrangement hole 15 are configured to be light absorbing or diffusing with respect to the inner side. In the configuration shown in FIG. 19, a film 19 g having a low reflectance such as a black film is formed on the inner peripheral surfaces of the hole 12 and the lens arrangement hole 15, so that the light reaching the inner peripheral surface is formed.
  • a rough surface 19h similar to the rough surfaces 18c and 18d described above is formed on the inner peripheral surfaces of the hole 12 and the lens arrangement hole 15, and the light reaching the rough surface 19h. And the rate of incidence on the light receiving optical fiber 42 is reduced.
  • the rough surface 19h can also be formed simultaneously with the molding of the tip member 10 by transferring the rough surface of the mold surface for molding the hole 12 and the lens arrangement hole 15.
  • a large number of streak grooves 19 i are formed on the inner peripheral surfaces of the hole 12 and the lens arrangement hole 15.
  • the rate at which the incident light is diffused in the direction away from the center of the probe and incident on the light receiving optical fiber 42 is reduced.
  • the lens 44 is fixed to the tip member 10 by locking the lens 44 at a step portion between the lens arrangement hole 15 in which the lens 44 is arranged and the hole portion 12 in front of the lens 44 and the tip member 10. It can be fixed by applying an adhesive to the contact portion. Further, as shown in FIG. 22, a lens portion 44c may be integrally formed as a part of the tip member 10c. In this case, it is not necessary to assemble and fix the lens and the tip member, and the positional accuracy of the lens portion 44c can be improved by eliminating the assembly error. In addition, small lenses are often hemispherical lenses due to processing convenience, but by forming the lens integrally with the tip member, it is possible to process double-sided aspherical lenses, etc. Will improve.
  • the optical fiber irradiates the measurement target site with the excitation light and receives the fluorescence generated due to the excitation light.
  • the present invention can be used for optical measurement of living tissue.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endoscopes (AREA)

Abstract

La sonde ci-décrite peut effectuer une mesure précise en douceur alors qu'une charge sur la zone de tissu corporel à mesurer est éliminée autant que possible. La sonde (1) selon l'invention destinée à être insérée dans un endoscope (100) comprend : une fibre optique d'irradiation (41), qui guide la lumière d'irradiation pour la mesure ; une fibre optique réceptrice de lumière (42), qui reçoit la lumière de radiation irradiée par la zone qui doit être mesurée (3a), et la guide côté extrémité de base de la sonde ; une fibre optique d'éclairage (43), qui guide la lumière d'éclairage ; et un élément d'extrémité avant (10), qui se trouve dans une partie extrémité avant de la sonde. L'élément d'extrémité avant traverse et diffuse la lumière d'éclairage qui a été guidée jusqu'à lui au moyen de la fibre optique d'éclairage, irradiant ainsi la lumière d'éclairage sur une plage prédéfinie, comprenant des zones dans le sens extrémité avant de la sonde. La sonde a une forme cylindrique ou autre qui, sans être en contact avec la zone à mesurer, vient buter sur le tissu corporel (3) dans une zone entourant la zone à mesurer, permettant ainsi que la partie extrémité avant de la sonde soit alignée avec la zone à mesurer.
PCT/JP2012/062495 2011-06-20 2012-05-16 Sonde WO2012176562A1 (fr)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015016021A (ja) * 2013-07-09 2015-01-29 オリンパス株式会社 照明装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07222712A (ja) * 1994-02-10 1995-08-22 Olympus Optical Co Ltd 蛍光内視鏡装置
JPH11244220A (ja) * 1998-03-03 1999-09-14 Fuji Photo Film Co Ltd 蛍光内視鏡
JP2003310543A (ja) * 2002-04-25 2003-11-05 Fuji Photo Film Co Ltd 蛍光内視鏡装置

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07222712A (ja) * 1994-02-10 1995-08-22 Olympus Optical Co Ltd 蛍光内視鏡装置
JPH11244220A (ja) * 1998-03-03 1999-09-14 Fuji Photo Film Co Ltd 蛍光内視鏡
JP2003310543A (ja) * 2002-04-25 2003-11-05 Fuji Photo Film Co Ltd 蛍光内視鏡装置

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015016021A (ja) * 2013-07-09 2015-01-29 オリンパス株式会社 照明装置

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