WO2012111965A3 - 경구투여용 탐술로신 또는 이의 약제학적으로 허용되는 염을 포함하는 서방성 삼중정제 - Google Patents

경구투여용 탐술로신 또는 이의 약제학적으로 허용되는 염을 포함하는 서방성 삼중정제 Download PDF

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Publication number
WO2012111965A3
WO2012111965A3 PCT/KR2012/001116 KR2012001116W WO2012111965A3 WO 2012111965 A3 WO2012111965 A3 WO 2012111965A3 KR 2012001116 W KR2012001116 W KR 2012001116W WO 2012111965 A3 WO2012111965 A3 WO 2012111965A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutically acceptable
acceptable salt
orally administered
layer
pill containing
Prior art date
Application number
PCT/KR2012/001116
Other languages
English (en)
French (fr)
Other versions
WO2012111965A2 (ko
Inventor
박정수
심지연
박준상
Original Assignee
지엘팜텍주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 지엘팜텍주식회사 filed Critical 지엘팜텍주식회사
Priority to ES12747874.1T priority Critical patent/ES2628902T3/es
Priority to PL12747874T priority patent/PL2676661T3/pl
Priority to EP12747874.1A priority patent/EP2676661B1/en
Publication of WO2012111965A2 publication Critical patent/WO2012111965A2/ko
Publication of WO2012111965A3 publication Critical patent/WO2012111965A3/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 탐술로신 또는 이의 약제학적으로 허용되는 염을 포함하는 경구투여용 서방성 삼중정제에 관한 것으로, 보다 상세하게는 구조적으로 분리된 삼중정제에서 탐술로신의 활성 소실없이, 중간층에 위치한 수용성 부형제에 의해 신속하고 지속적으로 많은 양의 수분을 흡수하여 결장을 포함한 하부 소화관 내에서도 약물을 방출 및 흡수시킬 수 있는 제제에 관한 것이다.
PCT/KR2012/001116 2011-02-15 2012-02-14 경구투여용 탐술로신 또는 이의 약제학적으로 허용되는 염을 포함하는 서방성 삼중정제 WO2012111965A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES12747874.1T ES2628902T3 (es) 2011-02-15 2012-02-14 Píldora de triple capa de liberación sostenida administrada por vía oral que contiene tamsulosina o sal farmacéuticamente aceptable de la misma
PL12747874T PL2676661T3 (pl) 2011-02-15 2012-02-14 Podawana doustnie trójwarstwowa pigułka o przedłużonym uwalnianiu zawierająca tamsulosynę lub jej farmaceutycznie dopuszczalną sól
EP12747874.1A EP2676661B1 (en) 2011-02-15 2012-02-14 Orally administered sustained-release triple-layer pill containing tamsulosin or pharmaceutically acceptable salt thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020110013099A KR102027912B1 (ko) 2011-02-15 2011-02-15 경구투여용 탐술로신 또는 이의 약제학적으로 허용되는 염을 포함하는 서방성 삼중정제
KR10-2011-0013099 2011-02-15

Publications (2)

Publication Number Publication Date
WO2012111965A2 WO2012111965A2 (ko) 2012-08-23
WO2012111965A3 true WO2012111965A3 (ko) 2012-11-01

Family

ID=46673040

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/001116 WO2012111965A2 (ko) 2011-02-15 2012-02-14 경구투여용 탐술로신 또는 이의 약제학적으로 허용되는 염을 포함하는 서방성 삼중정제

Country Status (5)

Country Link
EP (1) EP2676661B1 (ko)
KR (1) KR102027912B1 (ko)
ES (1) ES2628902T3 (ko)
PL (1) PL2676661T3 (ko)
WO (1) WO2012111965A2 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150092385A (ko) 2014-02-03 2015-08-13 씨제이헬스케어 주식회사 솔리페나신을 포함하는 안정한 제제 및 이의 제조방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001030322A1 (en) * 1999-10-29 2001-05-03 Universiteit Leiden Swellable delivery system
KR20040045148A (ko) * 2002-11-22 2004-06-01 센츄론(주) 탐술로신 또는 약제학적으로 허용되는 이의 염을활성성분으로 하는 서방성 배뇨장애 치료제
US6861070B1 (en) * 1998-06-26 2005-03-01 Yamanouchi Pharmaceutical Co., Ltd. Medicinal compositions for treating evacuatory insufficiency
US20070270459A1 (en) * 2002-06-07 2007-11-22 Astellas Pharma Inc. Overactive bladder treating drug
KR20080073989A (ko) * 2007-02-07 2008-08-12 지엘팜텍 주식회사 경구투여용 서방성 삼중정제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0661045T3 (da) 1992-09-18 2002-10-28 Yamanouchi Pharma Co Ltd Hydrogelpræparat med forsinket frigivelse
CA2387705C (en) 1999-08-04 2009-06-30 Yamanouchi Pharmaceutical Co., Ltd. Stable pharmaceutical composition for oral use
US7442387B2 (en) 2003-03-06 2008-10-28 Astellas Pharma Inc. Pharmaceutical composition for controlled release of active substances and manufacturing method thereof
KR100582350B1 (ko) 2004-02-17 2006-05-22 한미약품 주식회사 탐수로신 염산염의 경구투여용 조성물 및 이의 서방성과립 제제

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861070B1 (en) * 1998-06-26 2005-03-01 Yamanouchi Pharmaceutical Co., Ltd. Medicinal compositions for treating evacuatory insufficiency
WO2001030322A1 (en) * 1999-10-29 2001-05-03 Universiteit Leiden Swellable delivery system
US20070270459A1 (en) * 2002-06-07 2007-11-22 Astellas Pharma Inc. Overactive bladder treating drug
KR20040045148A (ko) * 2002-11-22 2004-06-01 센츄론(주) 탐술로신 또는 약제학적으로 허용되는 이의 염을활성성분으로 하는 서방성 배뇨장애 치료제
KR20080073989A (ko) * 2007-02-07 2008-08-12 지엘팜텍 주식회사 경구투여용 서방성 삼중정제

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2676661A4 *

Also Published As

Publication number Publication date
WO2012111965A2 (ko) 2012-08-23
KR20120093500A (ko) 2012-08-23
EP2676661A2 (en) 2013-12-25
KR102027912B1 (ko) 2019-10-02
EP2676661B1 (en) 2017-03-22
ES2628902T3 (es) 2017-08-04
PL2676661T3 (pl) 2017-10-31
EP2676661A4 (en) 2015-06-10

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