WO2012104051A1 - Trifunctional crosslinking reagents - Google Patents

Trifunctional crosslinking reagents Download PDF

Info

Publication number
WO2012104051A1
WO2012104051A1 PCT/EP2012/000392 EP2012000392W WO2012104051A1 WO 2012104051 A1 WO2012104051 A1 WO 2012104051A1 EP 2012000392 W EP2012000392 W EP 2012000392W WO 2012104051 A1 WO2012104051 A1 WO 2012104051A1
Authority
WO
WIPO (PCT)
Prior art keywords
crosslinking reagents
ligand
methods
glycopeptides
trifunctional crosslinking
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2012/000392
Other languages
English (en)
French (fr)
Inventor
Andreas Frei
Bernd Wollscheid
Ock-Youm Jeon
Erick Carreira
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eidgenoessische Technische Hochschule Zurich ETHZ
Original Assignee
Eidgenoessische Technische Hochschule Zurich ETHZ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eidgenoessische Technische Hochschule Zurich ETHZ filed Critical Eidgenoessische Technische Hochschule Zurich ETHZ
Priority to JP2013552130A priority Critical patent/JP5886324B2/ja
Priority to CA2825066A priority patent/CA2825066C/en
Priority to US13/982,596 priority patent/US9766235B2/en
Priority to AU2012213753A priority patent/AU2012213753B2/en
Priority to KR1020137022905A priority patent/KR101845581B1/ko
Priority to EP12702963.5A priority patent/EP2670755B1/en
Priority to CN2012800108848A priority patent/CN103403011A/zh
Publication of WO2012104051A1 publication Critical patent/WO2012104051A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PCT/EP2012/000392 2011-01-31 2012-01-30 Trifunctional crosslinking reagents Ceased WO2012104051A1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2013552130A JP5886324B2 (ja) 2011-01-31 2012-01-30 三官能性架橋剤
CA2825066A CA2825066C (en) 2011-01-31 2012-01-30 Trifunctional crosslinking reagents comprising a succinimide, a hydrazone and an affinity group
US13/982,596 US9766235B2 (en) 2011-01-31 2012-01-30 Trifunctional crosslinking reagents
AU2012213753A AU2012213753B2 (en) 2011-01-31 2012-01-30 Trifunctional crosslinking reagents
KR1020137022905A KR101845581B1 (ko) 2011-01-31 2012-01-30 3관능성 가교 시약
EP12702963.5A EP2670755B1 (en) 2011-01-31 2012-01-30 Trifunctional crosslinking reagents
CN2012800108848A CN103403011A (zh) 2011-01-31 2012-01-30 三官能交联试剂

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11000731 2011-01-31
EP11000731.7 2011-01-31

Publications (1)

Publication Number Publication Date
WO2012104051A1 true WO2012104051A1 (en) 2012-08-09

Family

ID=45569544

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2012/000392 Ceased WO2012104051A1 (en) 2011-01-31 2012-01-30 Trifunctional crosslinking reagents

Country Status (8)

Country Link
US (1) US9766235B2 (https=)
EP (2) EP2942351B1 (https=)
JP (1) JP5886324B2 (https=)
KR (1) KR101845581B1 (https=)
CN (1) CN103403011A (https=)
AU (1) AU2012213753B2 (https=)
CA (1) CA2825066C (https=)
WO (1) WO2012104051A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017081069A1 (en) * 2015-11-10 2017-05-18 Eth Zurich Tri-functional crosslinking reagents
US11378574B2 (en) 2014-02-27 2022-07-05 Sysmex Corporation Reagent for detecting target substance containing sugar chain, detection method, carrier used in detection of target substance containing sugar chain, and method for manufacturing said carrier

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3430769A4 (en) * 2016-03-18 2019-11-20 Coco Communications Corp. SYSTEMS AND METHODS FOR THE COMMON USE OF NETWORK INFORMATION
JP7325243B2 (ja) * 2018-06-27 2023-08-14 東ソー株式会社 アルデヒド捕捉剤
CN110873772B (zh) * 2018-08-30 2023-05-23 南方科技大学 一种探针及其合成方法和应用
CN111220679B (zh) * 2018-11-23 2022-08-02 中国科学院大连化学物理研究所 基于化学交联质谱解析的质膜蛋白质相互作用的鉴定方法
CN110252079B (zh) * 2019-05-08 2022-03-15 天津大学 一种气味远程传输的方法
US11470038B1 (en) 2020-05-19 2022-10-11 Marvell Asia Pte Ltd. Line side multiplexers with protection switching

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1203164A (en) * 1982-03-09 1986-04-15 Thomas J. Mckearn Antibody conjugates
GB9223168D0 (en) * 1992-11-05 1992-12-16 Johnson Matthey Plc Improvements in molecule labelling
WO1999051628A1 (en) * 1998-04-03 1999-10-14 Du Pont Pharmaceuticals Company Radiopharmaceuticals for imaging infection and inflammation and for imaging and treatment of cancer
AU8366398A (en) * 1998-07-07 2000-01-24 Department Of Radiation Oncology University Of Washington Trifunctional reagent for conjugation to a biomolecule
US7879799B2 (en) * 2006-08-10 2011-02-01 Institute For Systems Biology Methods for characterizing glycoproteins and generating antibodies for same
US8546531B2 (en) * 2008-07-16 2013-10-01 The General Hospital Corporation Methods and reagents for preparing multifunctional probes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
STEPHANIE PFANDER ET AL.: "Reversible site-specific tagging of enzymatically synthesized RNAs using aldehyde-hydrazine chemistry and protease-cleavable linkers", NUCLEIC ACIDS RESEARCH, vol. 35, no. 4, E25, 26 January 2007 (2007-01-26), pages 1 - 8, XP002672246 *
STEPHANIE PFANDER ET AL: "Supplementary data: Reversible site-specific tagging of enzymatically synthesized RNAs using aldehyde-hydrazine chemistry and protease-cleavable linkers", NUCLEIC ACIDS RESEARCH, 2007, pages S1 - S8, XP002673401 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11378574B2 (en) 2014-02-27 2022-07-05 Sysmex Corporation Reagent for detecting target substance containing sugar chain, detection method, carrier used in detection of target substance containing sugar chain, and method for manufacturing said carrier
WO2017081069A1 (en) * 2015-11-10 2017-05-18 Eth Zurich Tri-functional crosslinking reagents
KR20180102548A (ko) * 2015-11-10 2018-09-17 에테하 쭈리히 삼작용성 가교결합 시약
JP2018535214A (ja) * 2015-11-10 2018-11-29 イーティーエイチ・チューリッヒ 三官能性架橋試薬
AU2016353466B2 (en) * 2015-11-10 2020-10-01 Eth Zurich Tri-functional crosslinking reagents
US11385225B2 (en) 2015-11-10 2022-07-12 Eth Zurich Tri-functional crosslinking reagents
KR102656471B1 (ko) 2015-11-10 2024-04-11 에테하 쭈리히 삼작용성 가교결합 시약
US12306180B2 (en) 2015-11-10 2025-05-20 Eth Zurich Tri-functional crosslinking reagents

Also Published As

Publication number Publication date
EP2670755A1 (en) 2013-12-11
JP5886324B2 (ja) 2016-03-16
KR101845581B1 (ko) 2018-04-05
JP2014506879A (ja) 2014-03-20
CA2825066C (en) 2019-09-03
EP2942351A1 (en) 2015-11-11
CA2825066A1 (en) 2012-08-09
CN103403011A (zh) 2013-11-20
EP2942351B1 (en) 2016-10-12
KR20140020893A (ko) 2014-02-19
EP2670755B1 (en) 2016-10-12
US20140011212A1 (en) 2014-01-09
AU2012213753B2 (en) 2016-09-01
US9766235B2 (en) 2017-09-19

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