WO2012088675A1 - Solution de pulvérisation pour cigarette électronique - Google Patents

Solution de pulvérisation pour cigarette électronique Download PDF

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Publication number
WO2012088675A1
WO2012088675A1 PCT/CN2010/080444 CN2010080444W WO2012088675A1 WO 2012088675 A1 WO2012088675 A1 WO 2012088675A1 CN 2010080444 W CN2010080444 W CN 2010080444W WO 2012088675 A1 WO2012088675 A1 WO 2012088675A1
Authority
WO
WIPO (PCT)
Prior art keywords
vitamin
content
vitamins
electronic
electronic cigarette
Prior art date
Application number
PCT/CN2010/080444
Other languages
English (en)
Chinese (zh)
Inventor
徐爽
Original Assignee
深圳市奉天元电子有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳市奉天元电子有限公司 filed Critical 深圳市奉天元电子有限公司
Priority to PCT/CN2010/080444 priority Critical patent/WO2012088675A1/fr
Publication of WO2012088675A1 publication Critical patent/WO2012088675A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/308—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances vitamins
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Definitions

  • This invention relates to electronic aerosolization fluids and, more particularly, to a therapeutically effective electronic aerosolization fluid.
  • the technical problem to be solved by the present invention is to provide an electronic aerosolizing liquid which is beneficial to human health of smoking and surrounding second-hand smokers in view of the defects of the prior art electronic aerosolizing liquid which is not beneficial to human health.
  • the electronic aerosolization liquid includes the following materials: tobacco leaf extract, nicotine, a stabilizer, a thickener, propylene glycol, pure water, and a vitamin group.
  • the tobacco leaf extract has a content of 3-5% w/v; and the nicotine content is 0-3% w/v.
  • the stabilizer content is 0-1% w/v; the thickener is 1-8% w/v; the propylene glycol content is 50-70% w/v; and the pure water content is 3-5% w/v.
  • the vitamin group is contained in an amount of 0.01 to 2% w/v, and the vitamin group includes at least vitamins. C, vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B12, vitamin A, vitamin D, vitamin E, vitamin K One of folic acid.
  • the vitamin C content is 0.01-0.5% w/v.
  • the vitamin B1 content is 0.01-0.5% w/v
  • the vitamin B2 The content is 0.01-0.5% w/v
  • the content of vitamin B3 is 0.01-0.5% w/v
  • the content of vitamin B5 is 0.01-0.5% w/v
  • vitamin The content of B6 is 0.01-0.5% w/v
  • the content of vitamin B12 is 0.01-0.5% w/v.
  • the vitamin A content is 0.01-0.5% w/v.
  • the vitamin D is contained in an amount of 0.01 to 0.5% w/v.
  • the vitamin E content is 0.01-0.5% w/v.
  • the vitamin K is contained in an amount of 0.01 to 0.5% w/v.
  • the content of the folic acid is 0.01 - 0.5% w/v.
  • the implementation of the electronic aerosolization liquid of the present invention has the following beneficial effects: since the vitamins are added to the electronic aerosolization liquid of the present invention, It can enter the bloodstream through the capillaries in the mouth and circulate to our main organs, usually for 2-3 minutes. Increased absorption efficiency compared to syrup, tablets or capsules 10 Times. By adding vitamins to the electronic aerosolization solution, the smoker himself and the second-hand smoker colleague can achieve vitamin supplementation by inhaling the oral and nasal mucosa by inhaling the electronic cigarette smoke with vitamins.
  • the electronic cigarette atomization liquid of the invention adopts high-quality pure natural tobacco, and adopts modern extraction technology to separate the plant tobacco leaf essence which is harmless to the human body, and then is prepared by adding tobacco flavor and food additive. It includes the following substances: tobacco leaf extract, nicotine, stabilizer, thickener, propylene glycol, pure water, and also includes vitamin groups.
  • the content of tobacco leaf extract is 3-5% w/v; the content of nicotine is 0-3% w/v; the content of stabilizer is 0-1%. w/v; thickener 1-8% w/v; propylene glycol content 50-70% w/v; pure water content 3-5% w/v.
  • the vitamin group content is 0.01-2% w/v .
  • vitamins at least vitamin C, vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamins One of B6, vitamin B12, vitamin A, vitamin D, vitamin E, vitamin K, and folic acid.
  • the vitamin C content is 0.01-0.5% w/v.
  • the vitamin B1 content is 0.01-0.5% w/v
  • the vitamin B2 content is 0.01-0.5%
  • the content of w/v and vitamin B3 is 0.01-0.5% w/v
  • the content of vitamin B5 is 0.01-0.5% w/v
  • the content of vitamin B6 is The content of 0.01-0.5% w/v and vitamin B12 is 0.01-0.5% w/v.
  • the vitamin A content is 0.01-0.5% w/v.
  • the vitamin D content is 0.01-0.5% w/v.
  • the vitamin E content is 0.01-0.5% w/v.
  • the vitamin K content is 0.01-0.5% w/v.
  • the content of folic acid is 0.01-0.5% w/v.
  • the electronic aerosolization liquid of the present invention is used by adding an electronic aerosolization liquid to the smoke bomb of the electronic cigarette, opening the switch, and the electronic aerosolizer starts working and heating the atomization liquid to more than 100 °, the vitamins listed in the present invention are all soluble in water and can volatilize with water vapor when heated.
  • Vitamins include: Vitamin C 0.01-0.5% w/v , Vitamin B1 0.01-0.5% w/v, Vitamin B2 0.01-0.5% w/v, Vitamin B3 0.01-0.5% w/v, Vitamin B5 0.01-0.5% w/v, Vitamin B6 0.01-0.5% w/v, vitamin B12 0.01-0.5% w/v , vitamin A 0.01-0.5% w/v , vitamin D 0.01-0.5% w/v, vitamin E 0.01-0.5% w/v, vitamin K 0.01-0.5% w/v, folic acid 0.01-0.5% w/v.
  • the results of detecting the vitamin content in the electronic aerosolized liquid of the present embodiment are as follows: Test items Test results unit Detection method Vitamin C 54.6 Mg/100g Handbook of Food Composition Analysis, China Light Industry Press, 1998, first edition, Chapter 5, Section 1 Vitamin E 39.4 Mg/100g GB/T 5009.8-2003 Determination of vitamin A and vitamin E in foods Vitamin B1 40.3 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B2 41.4 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B3 50 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B5 55.7 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B6 44.2 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B12 45.6 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin A 43.9 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin D 30.2 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin K 36.7
  • the vitamin group includes: Vitamin C0.01-0.5% w/v.
  • the results of detecting the vitamin content in the electronic aerosolized liquid of the present embodiment are as follows: Test items Test results unit Detection method Vitamin C 57.8 Mg/100g Handbook of Food Composition Analysis, China Light Industry Press, 1998, first edition, Chapter 5, Section 1
  • Vitamins include: Vitamin C0.01-0.5% w/v , Vitamin B1 0.01-0.5% w/v .
  • the results of detecting the vitamin content in the electronic aerosolized liquid of the present embodiment are as follows: Test items Test results unit Detection method Vitamin C 45.6 Mg/100g Handbook of Food Composition Analysis, China Light Industry Press, 1998, first edition, Chapter 5, Section 1 Vitamin B1 35.8 Mg/100g Handbook of Food Composition Analysis, China Light Industry Press, 1998, first edition, Chapter 5, Section 1
  • Vitamins include: Vitamin C 0.01-0.5% w/v , Vitamin B1 0.01-0.5% w/v, Vitamin B2 0.01-0.5% w/v, Vitamin B3 0.01-0.5% w/v, Vitamin B5 0.01-0.5% w/v, Vitamin B6 0.01-0.5% w/v, vitamin B12 0.01-0.5% w/v , vitamin A 0.01-0.5% w/v , vitamin D 0.01-0.5% w/v , vitamin E 0.01-0.5% w/v.
  • the results of detecting the vitamin content in the electronic aerosolized liquid of the present embodiment are as follows: Test items Test results unit Detection method Vitamin C 55.6 Mg/100g Handbook of Food Composition Analysis, China Light Industry Press, 1998, first edition, Chapter 5, Section 1 Vitamin E 45.4 Mg/100g GB/T 5009.8-2003 Determination of vitamin A and vitamin E in foods Vitamin B1 44.5 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B2 43.7 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B3 51.2 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B5 49.2 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B6 44.2 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B12 44.4 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin A 42.1 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin D 31.2 Mg/100g Related Test Methods for Food Composition Analysis Manual
  • Vitamins include: Vitamin C 0.01-0.5% w/v , Vitamin B1 0.01-0.5% w/v, Vitamin B2 0.01-0.5% w/v, Vitamin B3 0.01-0.5% w/v, Vitamin B5 0.01-0.5% w/v, Vitamin B6 0.01-0.5% w/v, vitamin B12 0.01-0.5% w/v, vitamin E 0.01-0.5% w/v.
  • the results of detecting the vitamin content in the electronic aerosolized liquid of the present embodiment are as follows: Test items Test results unit Detection method Vitamin C 51.1 Mg/100g Handbook of Food Composition Analysis, China Light Industry Press, 1998, first edition, Chapter 5, Section 1 Vitamin E 41.4 Mg/100g GB/T 5009.8-2003 Determination of vitamin A and vitamin E in foods Vitamin B1 44.3 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B2 41.2 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B3 49.2 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B5 48.2 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B6 42.1 Mg/100g Related Test Methods for Food Composition Analysis Manual Vitamin B12 43.1 Mg/100g Related Test Methods for Food Composition Analysis Manual
  • the vitamin group includes: Vitamin E 0.01-0.5% w/v.
  • the results of detecting the vitamin content in the electronic aerosolized liquid of the present embodiment are as follows: Test items Test results unit Detection method Vitamin E 39.4 Mg/100g GB/T 5009.8-2003 Determination of vitamin A and vitamin E in foods
  • Vitamins include: Vitamin B1 0.01-0.5% w/v, Vitamin B2 0.01-0.5% w/v, Vitamin B3 0.01-0.5% w/v, Vitamin B5 0.01-0.5% w/v, Vitamin B6 0.01-0.5% w/v, Vitamin B12 0.01-0.5% w/v.
  • the electronic aerosolizing liquid of this embodiment is entrusted to Shenzhen Tianjian Testing Technology Service Co., Ltd., and the test report number is: SBW20100690.
  • the results of vitamin content testing are as follows: Test items Test results unit Detection method Vitamin C 54.6 Mg/100g Handbook of Food Composition Analysis, China Light Industry Press, 1998, first edition, Chapter 5, Section 1 Vitamin E 39.4 Mg/100g GB/T 5009.8-2003 Determination of vitamin A and vitamin E in foods
  • the capillaries and skin in the oral cavity are very close, and it is easy to absorb the nutrients in the oral cavity into the blood.
  • the electronic aerosolized liquid of the present invention uses the principle to add the vitamin added in the atomized solution from the oral cavity. Capillaries in the nasal cavity inhale blood, so a process only needs It can be reached in 30 seconds, so the nutrients can be recycled to the main organs, but the process is not too 2-3 It can be reached in minutes. This process can be compared with syrups, pills or capsules. The syrup, medicine or capsule needs to be absorbed through the gastrointestinal tract, which is wasted time and reduces the efficacy.
  • the oral and nasal absorption of the present invention can be carried out in a few seconds.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention se rapporte à une solution de pulvérisation pour cigarette électronique. Ladite solution de pulvérisation comprend un extrait de feuille de tabac, de la nicotine, un agent stabilisant, un agent épaississant, du glycol de propylène et de l'eau déminéralisée, et comprend en outre un groupe de vitamines. Puisque des vitamines sont ajoutées dans la solution de pulvérisation pour cigarette électronique, les vitamines peuvent arriver dans le sang et circuler dans les organes principaux par l'intermédiaire d'un vaisseau capillaire de la cavité buccal. Ce processus dure en général entre 2 et 3 minutes et augmente l'efficacité d'absorption de 10 fois par rapport à celle d'une décoction, d'un comprimé ou d'une capsule. Les fumeurs et également les fumeurs passifs inhalent en même temps l'aérosol contenant les vitamines de la cigarette électronique au moyen de vitamines supplémentaires se trouvant dans la solution de pulvérisation pour cigarette électronique. L'aérosol contenant les vitamines de la cigarette électronique transmet les vitamines au corps humain par l'intermédiaire de l'absorption de la membrane muqueuse de la bouche et du nez.
PCT/CN2010/080444 2010-12-29 2010-12-29 Solution de pulvérisation pour cigarette électronique WO2012088675A1 (fr)

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