WO2012068813A1 - Procédé de commande d'émission pour un biomicroscope ultrasonore à balayage linéaire fondé sur une fonction sinus - Google Patents

Procédé de commande d'émission pour un biomicroscope ultrasonore à balayage linéaire fondé sur une fonction sinus Download PDF

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Publication number
WO2012068813A1
WO2012068813A1 PCT/CN2011/072278 CN2011072278W WO2012068813A1 WO 2012068813 A1 WO2012068813 A1 WO 2012068813A1 CN 2011072278 W CN2011072278 W CN 2011072278W WO 2012068813 A1 WO2012068813 A1 WO 2012068813A1
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WIPO (PCT)
Prior art keywords
avg
speed
time
emission
fpga
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PCT/CN2011/072278
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English (en)
Chinese (zh)
Inventor
徐亮禹
陈浩
朱明善
Original Assignee
温州医学院眼视光学院
温州医学院眼视光研究院
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Application filed by 温州医学院眼视光学院, 温州医学院眼视光研究院 filed Critical 温州医学院眼视光学院
Publication of WO2012068813A1 publication Critical patent/WO2012068813A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52046—Techniques for image enhancement involving transmitter or receiver
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00—Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88—Sonar systems specially adapted for specific applications
    • G01S15/89—Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8934—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a dynamic transducer configuration
    • G01S15/8945—Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a dynamic transducer configuration using transducers mounted for linear mechanical movement

Definitions

  • the invention relates to a linear scanning emission technology of an ultrasonic biological microscope, in particular to an ultrasonic biological microscope scanning control method for diagnosis of ophthalmic diseases with an ultrasonic frequency above 35 Mhz.
  • Ultrasound Biomicroscope is a new type of ophthalmic B-ultrasound imaging equipment developed in the early 1990s.
  • UBM uses programmable logic device to control electronic circuits to excite high-frequency ultrasonic sensors to emit high-frequency ultrasound as a signal source, receive ultrasonic echo signals and perform electronic signal processing to obtain digital images related to inspection organization, and provide computer image processing technology for people.
  • a two-dimensional image of the anterior segment of the eye resembling a low-power optical microscope effect and different cross sections.
  • UBM has high resolution, real-time, quantitative and unaffected by opacity cornea and lens, and is widely used in ophthalmology.
  • UBM is currently widely used in the clinic for fan scanning and linear scanning.
  • Straight line scanning has the advantages of small image geometric distortion and wide image clarity.
  • the linear scanning mechanism is much more complicated than the sector scanning mechanism.
  • the application is more complicated by the uniform circular motion of the motor to convert into a linear reciprocating motion.
  • the radians of the ⁇ value [ ⁇ /6, ⁇ 5/6] are the effective paths of the line scan, and the range of V is [ 0. 5V, VI.
  • the present invention provides an elimination of geometric distortion and improved scanning path utilization.
  • the technical solution adopted by the present invention to solve the technical problem is: a sinusoidal function-based ultrasonic biological microscope linear scanning emission control method, and the circumference of the uniform circular motion process corresponding to the linear scanning motion process of the ultrasonic biological microscope is 1024
  • the circumferential speed point, the velocity value V of each speed point is the product of the circumferential speed value V and the sine value of the arc corresponding to the speed point
  • the uniform circular motion process is divided into 1023 segments, taking two adjacent speed points of each segment.
  • the circumference of the uniform circular motion is in the range of ⁇ /6 ⁇ ⁇ 5/6, the circular motion radius is R, and the effective scanning path distance is S.
  • FPGA is used as the controller, and the FPGA generates a pulse counter to set 1023 time compression parameters, and stores the generated data in the address order by the control data bus and the address bus to the corresponding storage RAM generated in the FPGA. When the ultrasonic sensor reaches the transmitting position, the FPGA will receive a trigger signal to start the emission control program.
  • the first time compression parameter in the storage RAM is read, and the time compression parameter is used.
  • start the timing program ie corresponding v avg (l)...v avg (1023)
  • the second transmit pulse can be transmitted, and then the second time compression parameter in the storage RAM is read, so that it is read in a specific order.
  • 1023 time compression parameters complete control of 1024 pulse transmissions.
  • the technical idea of the present invention is as follows:
  • the sinusoidal function of the ultrasonic biological microscope linear scanning emission mode because the scanning process is not completely linearly moving, but is related to the sin function, the maximum speed is twice as high as the minimum speed.
  • the invention is to make up for the deficiencies of the above scanning methods, and the equal spacing of each emission during the linear motion process strictly controls the geometric distance precision, so that the image has no geometric distortion. Take 1024 values equidistant on the effective circumference and use the adjacent two linear speeds to find 1023 average speeds. Use the following matlab command:
  • the v matrix is the instantaneous velocity of 1024 linear motion points.
  • the matrix of V is as follows: [0.5000V, 0.5018V, 0.5035V, 0.5053V...0.5053V, 0.5035V, 0.5018V, 0.5000 V];
  • v avg is The average velocity of two points of adjacent V has 1023 average speeds, and the matrix is as follows: [0.5009V, 0.5027V, 0.5044V, 0.5062V...0.5062V, 0.5044V, 0.5027V, 0.5009V]. Since the sin function is an even function, the value of v avg is also center symmetric. Let the circular motion frequency be f.
  • the beneficial effects of the present invention are mainly manifested in: the geometric distortion is very small, and the scanning path utilization rate is high.
  • Figure 1 is a block diagram of the principle of linear scanning emission control for ultrasonic biomicroscopy based on sinusoidal function.
  • Figure 2 is a schematic illustration of a linear scan path.
  • a sinusoidal function-based ultrasonic biological microscope linear scanning emission control method which takes 1024 circumferential speed points for the uniform distance of the uniform circular motion process corresponding to the linear scanning motion process of the ultrasonic biological microscope, each speed point
  • the velocity value V is the product of the circumferential velocity value V and the sine value of the arc corresponding to the velocity point.
  • the uniform circular motion process is divided into 1023 segments, and the average value of the velocity values V of each of the two adjacent velocity points is taken as
  • the circumference of the uniform circular motion is in the range of ⁇ /6 ⁇ ⁇ 5/6, the circular motion radius is R, and the effective scanning path distance is S.
  • the FPGA uses FPGA as the controller, the FPGA generates a pulse counter to set 1023 time compression parameters, and stores the generated data in the address order by the control data bus and the address bus to the corresponding storage RAM generated in the FPGA, when the ultrasonic sensor reaches the emission.
  • the FPGA will receive a trigger signal to start the emission control program.
  • the first time compression parameter in the storage RAM is read, and the time compression parameter is started to start the timing program, that is, corresponding v Avg (l)...v avg (1023)
  • the second transmit pulse can be transmitted, and then the second time compression parameter in the storage RAM is read, so that 1023 is read in a specific order. Time compression parameters to complete the control of 1024 pulse transmissions.
  • the uniform circular motion of the motor is used to convert into a linear reciprocating motion.
  • an equally spaced ultrasonic pulse is transmitted in a linear motion with uneven velocity.
  • the overall idea is to dynamically compress the emission time during the linear motion of uneven velocity.
  • the specific control process is as follows: 1024 effective peripheral speed points are taken on the circumference of the uniform circular motion process, and the horizontal linear speeds corresponding to each point are different, because the scanning motion range is very small, in the clinical use process In the effective scanning range of 16mm, the panoramic scan of the anterior segment of the ultrasound biomicroscopy can be realized. Based on the integration principle, the small-range scan can be considered to have 1023 uniform scanning line segments with a velocity of v avg (i).
  • the invention uses an FPGA (Field Programmable Gate Array) as a controller.
  • the FPGA has sufficient 10 and internal resources and flexible control methods, and uses a PLL (Phase Locked Loop) inside the FPGA to output different clock pulses of different frequencies. Controlling the reading of the ultrasound transmitting circuitry and time compression parameters.
  • the FPGA When the system is reset, the FPGA will generate a pulse counter to set 1023 time compression parameters, and store the generated data in the address sequence to the corresponding FPGA internal RAM by controlling the data bus and the address bus, so that not only the read/write speed is fast. And does not increase peripheral devices.
  • the FPGA will receive a trigger signal to start the emission control program.
  • the first time compression parameter in the storage RAM is read, and the time compression parameter is used to start the timing.
  • the program ie, the time of v avg (l)...v avg (1023)
  • the second transmission pulse can be transmitted, and then the second time compression parameter in the storage RAM is read, so
  • the control of 1024 pulse transmissions can be completed.
  • the FPGA PLL output 60Mhz clock can be used for calculation, and each clock cycle is 16.7ns.
  • the maximum number of clocks is 8056 (134550/16.7).
  • each value of T needs to be counted in a clock cycle of 60 Mhz, and the count value of the integer is used instead of the compression parameter of time.
  • the FPGA automatically generates the clock count value after each T conversion, such as 8056 (decimal), and writes the generated clock count value to the internally generated RAM in order from the address bus to the internally generated RAM.
  • 512 X 16 RAM can be used to save Store data because the T value is symmetrical at both ends.
  • the data in the 000000000 (binary) address in the storage RAM is read immediately after the FPGA first enables the ultrasonic transmission pulse, and the timing program is started according to the read data.
  • the timing program decrements the data by the number of clocks. The corresponding timing is completed until the data is zero.
  • the second ultrasonic transmission pulse can be enabled, and then the data in the 000000001 (binary) address in the storage RAM is read, and the timing data is also started by the read data until the address of the RAM is 111111110 (binary ), that is, the central data of the T value, the 512th data.
  • the reading of the 513th to the 10thth data needs to be read by the address decrement, that is, the 513th data address is 111111101 (binary), and the 1023th data address is 000000000 (binary).
  • the address is first added and then decremented to take the value, and the corresponding timing program is started, so that the dynamic time compression function can be completed, and the ultrasonic isometric emission can be realized.

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Radar, Positioning & Navigation (AREA)
  • Remote Sensing (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • General Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

L'invention concerne un procédé de commande d'émission pour un biomicroscope ultrasonore à balayage linéaire fondé sur une fonction sinus, permettant de commander l'émission en fonction d'un temps d'émission de chaque section, comprenant les étapes suivantes : (1) 1024 points de vitesse circulaire sont acquis sur la circonférence lors du processus de mouvement circulaire uniforme avec équidistance, ce qui correspond au processus de mouvement de balayage linéaire du biomicroscope ultrasonore. La vitesse (v) de chaque point de vitesse est égale au produit du sinus de l'arc circulaire où se trouve le point de vitesse et la valeur de vitesse circulaire (V). (2) La vitesse moyenne de chaque section vavg(i),i=1,2...1023 est égale à la valeur moyenne de la vitesse (v) de deux points de vitesse adjacents. (3) La plage d'émission s de chaque section est calculée en fonction de la formule S=R/1023=0.001693R, dans laquelle R représente le rayon de mouvement circulaire, et l'étendue radiale de la circonférence est égale à π/6~π5/6. (4) Le temps d'émission de chaque section est calculée en fonction de T=S/vavg(i). L'invention permet d'éliminer les distorsions géométriques, d'améliorer le rapport d'utilisation de la trajectoire de balayage et de favoriser la qualité des images.
PCT/CN2011/072278 2010-11-26 2011-03-30 Procédé de commande d'émission pour un biomicroscope ultrasonore à balayage linéaire fondé sur une fonction sinus WO2012068813A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201010561828.6 2010-11-26
CN 201010561828 CN102068282B (zh) 2010-11-26 2010-11-26 基于正弦函数的超声生物显微镜直线扫描发射控制方法

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WO2012068813A1 true WO2012068813A1 (fr) 2012-05-31

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CN (1) CN102068282B (fr)
WO (1) WO2012068813A1 (fr)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997793A (en) * 1975-11-07 1976-12-14 University Of Michigan Apparatus and method for locating and quantifying or directing a source of ionizing radiation
CA1160727A (fr) * 1978-06-16 1984-01-17 Christoph B. Burckhardt Emetteur pour appareil de visualisation a ultrasons
JPH02241445A (ja) * 1989-03-15 1990-09-26 Fuji Electric Co Ltd 眼科用超音波プローブ
CN1909835A (zh) * 2004-10-20 2007-02-07 株式会社东芝 超声波诊断设备以及控制超声波诊断设备的方法
CN101288585A (zh) * 2007-04-17 2008-10-22 天津市索维电子技术有限公司 一种超声生物显微镜检查实现眼科前节的全景成像方法
CN201346214Y (zh) * 2008-12-22 2009-11-18 温州医学院眼视光器械有限公司 一种新型眼科超声生物显微镜的扫描机械装置
CN201510300U (zh) * 2009-09-29 2010-06-23 天津迈达医学科技有限公司 新型线性扫描超声探头

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100500101C (zh) * 2007-01-11 2009-06-17 北京航空航天大学 B型超声电磁式机械扇扫描装置
CN100500102C (zh) * 2007-06-12 2009-06-17 北京航空航天大学 B型超声位置反馈式机械扇扫探头装置

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997793A (en) * 1975-11-07 1976-12-14 University Of Michigan Apparatus and method for locating and quantifying or directing a source of ionizing radiation
CA1160727A (fr) * 1978-06-16 1984-01-17 Christoph B. Burckhardt Emetteur pour appareil de visualisation a ultrasons
JPH02241445A (ja) * 1989-03-15 1990-09-26 Fuji Electric Co Ltd 眼科用超音波プローブ
CN1909835A (zh) * 2004-10-20 2007-02-07 株式会社东芝 超声波诊断设备以及控制超声波诊断设备的方法
CN101288585A (zh) * 2007-04-17 2008-10-22 天津市索维电子技术有限公司 一种超声生物显微镜检查实现眼科前节的全景成像方法
CN201346214Y (zh) * 2008-12-22 2009-11-18 温州医学院眼视光器械有限公司 一种新型眼科超声生物显微镜的扫描机械装置
CN201510300U (zh) * 2009-09-29 2010-06-23 天津迈达医学科技有限公司 新型线性扫描超声探头

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CN102068282B (zh) 2012-07-18

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