WO2012060400A1 - Dispositif de mesure de constituants de fluides corporels - Google Patents

Dispositif de mesure de constituants de fluides corporels Download PDF

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Publication number
WO2012060400A1
WO2012060400A1 PCT/JP2011/075266 JP2011075266W WO2012060400A1 WO 2012060400 A1 WO2012060400 A1 WO 2012060400A1 JP 2011075266 W JP2011075266 W JP 2011075266W WO 2012060400 A1 WO2012060400 A1 WO 2012060400A1
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WO
WIPO (PCT)
Prior art keywords
test tool
test
fluid component
housing
body fluid
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Application number
PCT/JP2011/075266
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English (en)
Japanese (ja)
Inventor
隆行 杉山
Original Assignee
テルモ株式会社
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Filing date
Publication date
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Publication of WO2012060400A1 publication Critical patent/WO2012060400A1/fr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band

Definitions

  • the present invention relates to a bodily fluid component measuring device that measures the amount and property of a predetermined component in a body fluid such as blood sugar level in blood, and in particular, a part of a housing is made flexible so that the flexibility It is related with the humor component measuring apparatus comprised so that it could discharge
  • the tester himself / herself directly grips the used test piece (test device) by hand, and the test piece is pulled out from the test piece mounting portion where the test piece is mounted and discarded. Therefore, the hand touches the blood adhering to the used test piece, which is not preferable from the viewpoint of hygiene.
  • a measuring device having a discharging mechanism that discharges a test piece without touching it is also provided.
  • the discharging mechanism used in this measuring device uses components such as a spring, a pushing member, and a knob. For this reason, there are problems such as an increase in the number of parts, which is uneconomical.
  • a measuring device for measuring a sample such as a body fluid as described in Patent Document 1, for example.
  • This measuring apparatus is a measuring apparatus that is equipped with a sensor on which a sample is spotted and measures the sample, and is characterized by including a discharge mechanism that discharges the sensor from the measuring apparatus.
  • the purpose of the present invention is to reduce the number of parts such as eject levers and coil springs constituting the mechanism for discharging the test device in the conventional body fluid component measuring apparatus as described above, thereby reducing the manufacturing cost.
  • the purpose is to reduce this.
  • the present invention relates to a body fluid component measuring apparatus including a test device mounting portion on which a test device for measuring a body fluid component is mounted.
  • a test device mounting portion on which a test device for measuring a body fluid component is mounted.
  • a test equipment mounting part which can hold the test tool
  • a part of the housing facing the grip piece and a part of the housing facing the grip piece.
  • a fulcrum portion that contacts the gripping piece.
  • the gripping piece is provided with a flexible input part provided on the base end side from the fulcrum part. By pressing the input part, the gripping piece is rotated around the fulcrum part to release the grip of the test device. It is characterized by doing so.
  • a part of a housing is made flexible so that the test device can be discharged by bending and deforming the housing portion having flexibility. Configured. Thereby, the used test tool can be discharged hygienically and processed without increasing the number of parts.
  • FIG. 2 is a perspective view in which a central portion of the body fluid component measuring device shown in FIG. 1 is longitudinally cut along a longitudinal direction. It is explanatory drawing which expanded the cross section of the principal part of the bodily fluid component measuring apparatus shown in FIG. It is a perspective view which shows the 2nd Example of the bodily fluid component measuring apparatus of this invention.
  • FIG. 5 is a perspective view in which a central portion of the body fluid component measuring device shown in FIG. 4 is longitudinally cut along the longitudinal direction. It is explanatory drawing which expanded the cross section of the principal part of the bodily fluid component measuring apparatus shown in FIG.
  • 1 to 3 are diagrams showing a blood glucose meter 1 according to a first embodiment of a body fluid component measuring apparatus of the present invention.
  • 4 to 8 are views showing a blood glucose meter 100 according to a second embodiment of the body fluid component measuring apparatus of the present invention.
  • 9 to 12 are views showing a blood glucose meter 200 according to a third embodiment of the body fluid component measuring apparatus of the present invention.
  • the present invention is not limited to the blood glucose meter 1, 100, 200 shown in the first to third embodiments.
  • the blood glucose meter 1 shown in FIGS. 1 to 3 is a hospital-use product suitable for use by medical personnel such as doctors and nurses mainly for patients admitted to medical facilities.
  • the blood glucose meter 1 may be used by a patient at home or the like.
  • the blood glucose meter 1 can be used by a doctor, a nurse or the like by holding it like a mobile phone or by placing it on a desk or a medical table.
  • the main function of the blood glucose meter 1 is to measure the blood glucose level in the blood and manage the measurement data.
  • the blood glucose meter 1 has functions such as confirmation of the patient's name and medicine to be administered, and accuracy management of the device. It may be added.
  • the blood glucose meter 1 displays a housing 2 formed of a hollow container, a measurement unit 3 built in the housing 2, input items, confirmation items, measurement results, and the like.
  • the display unit 4 includes a control unit 5 that controls the operation of the measurement unit 3 and the display unit 4, a power supply unit that supplies power to the display unit 4, the control unit 5, and the like.
  • the housing 2 is formed as a rectangular parallelepiped container having an elongated trunk so that a person can hold it with one hand and easily press the operation button of the operation unit.
  • the housing 2 includes a container body 7 having an opening at the back, which is one end face in the longitudinal direction of the rectangular parallelepiped, and a lid 8 that closes the back opening of the container body 7.
  • the lid body 8 is fixed to the container body 7.
  • a material of the housing 2 for example, ABS resin (acrylonitrile / butadiene / styrene resin) or polycarbonate (PC) can be used.
  • PC polycarbonate
  • the present invention is not limited to this, and various engineering plastics having a certain degree of strength and capable of exhibiting appropriate flexibility (bending deformation) can be used.
  • a display unit 4 that displays the blood sugar level calculated by the control unit 5 based on the information measured by the measurement unit 3 is provided.
  • the display unit 4 has an opening window 11 having a rectangular shape penetrating the upper surface of the container body 7 and extending in the longitudinal direction.
  • the opening window 11 has a transparent panel cover having a shape corresponding to the opening window 11. 12 is mounted.
  • a display panel 13 capable of displaying characters, graphics and the like is disposed on the inner surface of the panel cover 12.
  • the display panel 13 is configured by, for example, a liquid crystal display or an organic EL display.
  • the control unit 5 includes a storage device such as a microcomputer, ROM, and RAM, and a wiring board 15 on which a predetermined wiring pattern is formed. And the control part 5 is comprised by mounting a microcomputer and other electronic components in the predetermined position of the wiring board 15. FIG. The control unit 5 executes predetermined arithmetic processing based on a measurement signal supplied from the measurement unit 3 described later and outputs a control signal.
  • the power supply unit includes a battery as a portable power supply, and the operation of the measurement unit 3, the control unit 5 and the like is executed by the power of the battery, and the display of the display unit 4 is controlled. Yes.
  • An operation unit includes a power switch for turning on / off the power, an operation button for inputting an information signal, a command signal, and the like.
  • a barcode reader unit may be provided in the housing 2 so that patient ID information and the like can be read.
  • a test tool mounting portion 17 for mounting a test tool 30 for collecting blood is provided at the front end of the casing 2 in the longitudinal direction.
  • the test tool mounting portion 17 includes a ring-shaped cylindrical portion 18 having a circular cross-section projecting forward from the front surface of the housing 2, and the test tool 30 is detachably mounted to the cylindrical portion 18. Is done.
  • the cylindrical portion 18 is divided into two in the diameter direction by a cutting portion 21 extending in the axial direction.
  • the cutting portion 21 extends from the base end of the cylindrical portion 18 in the longitudinal direction of the container main body 7, and is a slit that is notched linearly to the middle portion of the container main body 7.
  • a grip piece 22 is formed on a part of the container body 7.
  • a portion of the grip piece 22 close to the base end portion of the cutting portion 21 serves as an input unit 23 that is pressed and elastically deformed to displace the grip piece 22.
  • the input unit 23 constitutes a part of the housing 2 and is formed so as to be thin and flexible compared to the portion of the housing 2 other than the input unit 23.
  • the input portion 23 may be formed so as to slightly bulge to the outer surface side, and may be provided so as to be deformed to the inner surface side by being pressed and buckled or reversed.
  • the input unit 23 may be formed of a flexible material different from other parts of the housing 2, for example, polyethylene (PE), polypropylene (PP), ethylene-vinyl acetate copolymer (EVA). ), A styrene-based or olefin-based thermoplastic elastomer, or a composite material thereof.
  • the input unit 23 and the other part of the housing 2 can be integrally formed by two-color molding.
  • a claw portion 24 for gripping the test device 30 is provided, and the claw portion 24 is formed as a semi-cylindrical portion forming the upper half of the cylindrical portion 18.
  • a test device 30 that is detachably attached to the cylindrical portion 18 including the claw portion 24 has a configuration as shown in FIGS. That is, the test tool 30 includes a base portion 31 formed in a disk shape, a nozzle portion 32 formed on one surface of the base portion 31, and a cylindrical shaft portion formed on the other surface of the base portion 31. 33.
  • the outer diameter of the base portion 31 is formed to be approximately the same as the outer diameter of the cylindrical portion 18.
  • the nozzle portion 32 is erected at the center of the base portion 31, and a sampling hole 34 that penetrates in the axial direction and opens on the surface on the cylinder shaft portion 33 side is provided at the center portion.
  • the tip of the nozzle portion 32 is formed in a tapered shape, and a concave groove is provided at the tip for facilitating aspiration of blood, which is a specific example of the body fluid that is a specimen.
  • the cylindrical shaft portion 33 of the test device 30 is formed in a size that fits into the hole of the cylindrical portion 18 and is configured so that the cylindrical portion 18 is closed by the base portion 31. Furthermore, a plurality of engaging claws (four in this embodiment) 35 made of an elastic piece are provided at the tip of the cylindrical shaft portion 33 by providing a notch. By fitting the tube shaft part 33 into the hole of the cylindrical part 18, the test tool 30 is elastically held by the test tool mounting part 17 by the engaging claws 35.
  • the engaging claw 35 is formed as an arc-shaped convex portion that is continuous in the circumferential direction, and a convex portion having a mountain shape for increasing frictional resistance is provided on the outer peripheral surface thereof.
  • the test device 30 is a disposable product and is packaged in a package not shown.
  • the sampling hole 34 of the test device 30 is formed to have a sufficiently small diameter so that blood can be sucked up by capillary action so that the blood in contact with the tip of the nozzle portion 32 can move to the opening on the tube shaft portion 33 side. It has become.
  • a test paper 36 into which blood that has moved through the collection hole 34 is stored is stored in a test paper storage portion formed inside the tube shaft portion 33 of the test tool 30. By irradiating the test paper 36 with predetermined light emitted from the optical measurement unit 40, components in the blood can be measured.
  • test paper 36 examples include polyethersulfone.
  • examples of the reagent pre-impregnated in the test paper 36 include glucose oxidase (GOD), peroxidase (POD), 4-aminoantipyrine, N-ethyl N- (2-hydroxy-3-sulfopropyl) and the like. Mention may be made of color formers.
  • the reagent may contain a predetermined buffer.
  • the optical measuring unit 40 (measuring unit) is a device that irradiates the test paper 36 soaked with blood and receives the reflected light.
  • the optical measuring unit 40 includes a holder 41 attached to the bottom side of the housing 2, and a light emitting element and a light receiving element held by the holder 41.
  • the light emitting element is made of, for example, a light emitting diode
  • the light receiving element is made of, for example, a photodiode.
  • the light emitting element and the light receiving element of the optical measuring unit 40 are held inside a holder 41 having a passage extending to the end face on the test paper 36 side.
  • the light emitted from the light emitting element is applied to the test paper 36 through the passage, and the light reflected by the test paper 36 is guided to the light receiving element, and is photoelectrically converted by the light receiving element. Then, an analog signal corresponding to the amount of received light is output from the light receiving element to the control unit 5.
  • the holder 41 has a block-like base portion 41a and a cylindrical shaft portion 41b formed continuously on the front side of the base portion 41a. An irradiation port 37 for irradiating one test paper 36 with light of two types of wavelengths is opened in the shaft portion 41b.
  • the optical measurement unit 40 is disposed inside the cylindrical portion 18 and the gripping piece 22.
  • a ring-shaped space portion is formed between the shaft portion 41 b of the holder 41 and the cylindrical portion 18.
  • a cylindrical shaft portion 33 of the test device 30 is detachably inserted into a ring-shaped space formed in the cylindrical portion 18.
  • the space portion constitutes a test tool mounting portion 17 that can removably support the test tool (chip) 30.
  • the control unit 5 is provided on the wiring board 15 on the base end side of the holder 41 that holds the optical measurement unit 40.
  • the control unit 5 is electrically connected to the optical measurement unit 40 via a wiring pattern provided on the wiring board 15, and causes the light emitting element of the optical measurement unit 40 to emit light at an appropriate timing and is supplied from the light receiving element.
  • the analog signal is converted into a digital signal by an A / D converter (not shown). Further, the control unit 5 performs a predetermined calculation process based on the digital signal of the amount of received light, and calculates the blood sugar level in the blood. Then, the calculated blood glucose level is displayed on the display panel 13 to inform the measurer.
  • the holder 41 is provided with a fulcrum part 45 for rotating the grip piece 22 in accordance with the pressing operation of the input part 23.
  • the fulcrum part 45 is disposed on the upper surface of the holder 41 at an intermediate position between the claw part 24 of the gripping piece 22 and the input part 23.
  • the fulcrum portion 45 is preferably formed as a convex portion that contacts the inner surface of the gripping piece 22 in a state where the test piece 30 is gripped by the gripping piece 22, and the convex portion is a direction orthogonal to the direction in which the gripping piece 22 extends. It may be formed as a ridge extending in the right direction, or may be a plurality of protrusions formed with appropriate gaps in the orthogonal direction.
  • the fulcrum portion 45 is preferably a dome shape having a semicircular cross section with the upper surface curved in an arc shape in consideration of the rotation of the gripping piece 22 during elastic deformation. It is good also as a shape.
  • a packing is attached to the outer peripheral portion of the holder 41 in the housing 2 and the space between the holder 41 and the control unit 5 is sealed in a liquid-tight manner, so that the specimen, water, etc. Intrusion can be prevented.
  • the blood glucose meter 1 can be wiped clean or washed with water by interposing a packing at the fitting portion between the container body 7 and the lid body 8 and sealing it in a liquid-tight manner.
  • the blood glucose meter 1 having such a configuration can be assembled as follows, for example. Since one end of the container body 7 in the longitudinal direction is opened and the lid 8 is fitted to the opening, the optical measurement unit 40 and the control unit 5 are inserted through the opening. Thereafter, the lid 8 closes the opening and tightens it with a fixing screw, so that it can be easily assembled.
  • FIG. 1 shows a normal use state of the blood glucose meter 1, which is used by grasping the housing 2 so as to be grasped lightly with one hand.
  • the fingertip is punctured with a dedicated puncture device, and a small amount of blood (eg, about 0.3 to 1.5 ⁇ L) is allowed to flow out from the puncture portion onto the skin.
  • a small amount of blood eg, about 0.3 to 1.5 ⁇ L
  • the tip of the nozzle part 32 of the test device 30 attached to the tip of the blood glucose meter 1 is brought into contact with a small amount of blood on the fingertip.
  • blood enters the collection hole 34 of the nozzle portion 32, is sucked by capillary action, flows inward, and reaches the central portion of the test paper 36 accommodated in the tube shaft portion 33.
  • the blood that has reached the test paper 36 soaks into the test paper 36 from its surface and spreads radially outward.
  • the glucose in the blood and the reagent carried on the test paper 36 start to react and color according to the amount of glucose.
  • the blood glucose level can be determined by measuring the color of the colored test paper and measuring the color intensity.
  • the test tool 30 When the test tool 30 is ejected from the test tool mounting portion 17 after the measurement is completed, for example, the casing 2 is grasped with four fingers and palms except for the thumb, and the thumb is aligned with the input unit 23 and the input is performed. The part 23 is pressed.
  • the test instrument mounting part 17 has a gripping piece 22 which is made flexible by providing a cutting part 21 in the container body 7, and an input part 23 is provided at the root of the gripping piece 22. It is comprised so that a root part may be pressed. Further, since a fulcrum portion 45 is provided between the claw portion 24 at the tip and the input portion 23, when the input portion 23 is pressed with a predetermined external force F as shown in FIG. As a result, the gripping piece 22 is elastically deformed into a V shape.
  • the distal end side of the gripping piece 22 is rotated clockwise in FIG.
  • the claw portion 24 holding the upper half of the tube shaft portion 33 of the test device 30 mounted on the test device mounting portion 17 is separated from the tube shaft portion 33 and the test piece 30 is locked by the gripping piece 22. Canceled. Therefore, the test tool 30 is easily detached from the test tool mounting portion 17. Therefore, the test device 30 is easily detached from the test device mounting portion 17 by turning the blood glucose meter 1 downward with the test device 30 facing downward, or by lightly shaking the test device 30 by its own weight or vertically. Can be disposed of in a waste container.
  • the operator who operates the blood glucose meter 1 can separate the test device 30 from the blood glucose meter 1 and discard it by one-hand operation while holding the blood glucose meter 1 with one hand. Accordingly, the disposal of the test tool 30 can be performed hygienically and easily without touching the test tool 30.
  • FIGS. 4 to 8 are views showing a blood glucose meter 100 according to a second embodiment of the present invention.
  • This blood glucose meter 100 is provided with a test tool discharge mechanism 120 that automatically releases the test tool 130 at the same time as releasing the grip of the test tool (test piece) 130 by bending and deforming a part of the housing 102. It is.
  • the blood glucose meter 100 shown in this embodiment is different from the blood glucose meter 1 shown in the first embodiment, and measures the blood glucose level by electrochemical means. That is, the blood glucose meter 100 is equipped with an electrochemical sensor for measuring components in the blood, and can measure the blood glucose level based on the current value obtained from the reaction between the collected blood component and the reagent. It is a component measuring device.
  • the blood glucose meter 100 includes a casing 102 having a lower case 107 and an upper case 108.
  • the lower case 107 is a shallow container having a substantially rectangular shape opened on the upper surface, and a hook-like portion 109 protruding in the longitudinal direction is provided at the center of the front surface, which is one surface of the lower case 107 in the longitudinal direction. It has been.
  • An upper case 108 having a flat plate shape is superimposed on the lower case 107.
  • the upper case 108 is fixed to the lower case 107 by a fixing screw (not shown).
  • the hook-shaped portion 109 of the lower case 107 is a convex portion having a U-shaped cross-section and opened upward, and the upper surface opening portion projects into a tongue-like shape provided in the upper case 108 and has flexibility. It is closed by the gripping piece 122.
  • the gripping piece 122 is given flexibility by making a part of the base part thinner than the other part to weaken the strength.
  • a claw portion 124 that presses and fixes a portion close to the base end of the test tool (test piece) 130 is provided at the tip of the grip piece 122.
  • a thin portion provided at the base portion of the grip piece 122 serves as an input unit 123 for bending and deforming the grip piece 122. Note that the input unit 123 may be formed by integral molding using a member having flexibility different from that of other parts of the gripping piece 122.
  • fulcrum portions 145 and 145 including two protrusions are provided on the inner surface of the hook-shaped portion 109.
  • the two fulcrum portions 145 and 145 are arranged at a substantially intermediate portion in the longitudinal direction of the bowl-shaped portion 109 with a predetermined gap in the width direction intersecting with the longitudinal direction.
  • the upper end part of each fulcrum part 145 is formed as a circular-arc-shaped curved-surface part in order to make the bending deformation of the holding piece 122 easy.
  • a front end portion 109a having a rectangular entrance / exit 146 through which the test tool 130 is detachably inserted is provided at the central portion at the distal end portion in the longitudinal direction of the bowl-shaped portion 109.
  • the height of the front surface portion 109 a of the bowl-shaped portion 109 is set to the same height as the height of the fulcrum portion 145.
  • the lower surface of the gripping piece 122 abuts only the upper end surfaces on both sides of the front surface portion 109a and the two fulcrum portions 145 and 145, thereby opening the upper surface of the hook-shaped portion 109. It is comprised so that a part may be closed.
  • the claw portion 124 provided at the tip of the grip piece 122 is engaged with the entrance / exit 146 provided in the front surface portion 109 a of the hook-shaped portion 109, and the claw portion 124 causes the test tool 130 to be placed on the bottom surface of the hook-shaped portion 109. Grab as if pressing.
  • a guide groove 147 for guiding the test tool 130 is provided on the bottom surface of the bowl-shaped portion 109 continuously from the entrance / exit 146.
  • the guide groove 147 has the same width as the width of the test tool 130.
  • the measuring portion 103 is disposed inside the guide groove 147 inside the hook-shaped portion 109.
  • the measurement unit 103 includes a terminal block 150 having a plurality of conductive terminals 151 at the tip.
  • the terminal block 150 has a T-shaped planar shape, and is fixed to the hook-shaped portion 109 in a state where the protruding portion from which the conductive terminal 151 protrudes extends in the longitudinal direction of the hook-shaped portion 109. .
  • Two fulcrum portions 145 and 145 are arranged on both sides of the tip of the terminal block 150 with a predetermined gap.
  • the tips of the plurality of conductive terminals 151 are formed to be bent 180 degrees downward, and are configured so that the tips of the test tool 130 inserted from the entrance / exit 146 can be easily inserted.
  • the plurality of conductive terminals 151 can be elastically contacted with the base end portion of the test tool 130, and the distal end portion of the test tool 130 is inserted under the plurality of conductive terminals 151, whereby the electrode terminals of the test tool 130 are provided.
  • each conductive terminal 151 is electrically connected.
  • One end of the cable line 152 is connected to the terminal block 150, and the other end of the cable line 152 is connected to the connector 154 of the control unit 105.
  • Each conductive terminal 151 is biased toward the hook-shaped portion 109 and has a function of sandwiching and gripping the test tool 130 with the hook-shaped portion 109.
  • the connector 154 is mounted on a control unit wiring board (hereinafter referred to as a “wiring board”) 155 housed in the housing 102, and is provided on the wiring board 155.
  • the wiring pattern is electrically connected.
  • a display panel 113 forming a display unit is disposed above the wiring substrate 155.
  • the display panel 113 is integrally formed by being joined to the inner surface of the panel cover 112 attached to the opening window 111 provided in the upper case 108.
  • the control unit 105 includes a storage device such as a microcomputer, a ROM, and a RAM, and a predetermined wiring pattern, and is provided on the wiring board 155.
  • the control unit 105 is configured by mounting a microcomputer and other electronic components at predetermined positions on the wiring board 155.
  • the control unit 105 and the measurement unit 103 are electrically connected, and based on the measurement signal supplied from the measurement unit 103, the control unit 105 executes a predetermined calculation process and outputs a predetermined control signal.
  • the upper case 108 is provided with a power switch 114a and an operation button 114b of the operation unit 114.
  • a leaf spring 160 showing a specific example of a test tool push-out mechanism that pushes the test tool 130 outward from the entrance / exit 146 is provided inside the bowl-shaped portion 109.
  • the plate spring 160 is formed as a rectangular frame-shaped plate material.
  • a pressing portion 160a that abuts the test tool 130 and presses the test tool 130 is provided.
  • the pressing portion 160 a is provided with a notch portion 161 for avoiding contact with the conductive terminal 151. This notch portion 161 prevents the pressing portion 160 a from coming into contact with the plurality of conductive terminals 151 even when the test tool 130 is pushed out by the leaf spring 160.
  • the leaf spring 160 is formed in a crank shape as a whole by providing a mountain fold 160b and a valley fold 160c by bending two longitudinal portions in the plate thickness direction.
  • the leaf spring 160 has a mountain fold 160b provided on the side opposite to the pressing portion 160a and a valley fold 160c provided on the pressing portion 160a side.
  • the leaf spring 160 is attached to the terminal block 150 so that the end on the valley fold 160 c side faces the guide groove 147 and the end on the mountain fold 160 b is placed on the upper surface of the terminal block 150.
  • the convex portion side of the terminal block 150 is fitted into a central square hole provided in the leaf spring 160, thereby restricting the movement of the leaf spring 160 in the width direction and allowing forward and backward movement only in the longitudinal direction. I have to.
  • the blood glucose meter 100 having such a configuration can be assembled as follows, for example. First, the control unit 105 is assembled by attaching the wiring board 155 and the like to the lower case 107. Next, the terminal block 150 is attached to a predetermined position of the hook-shaped portion 109, and then the leaf spring 160 is attached to the terminal block 150. Then, the wiring board 155 and the terminal block 150 are electrically connected by the cable line 152.
  • the blood glucose meter 100 having such a configuration can be used as follows, for example. First, the test device 130 is attached to the test device mounting portion 117 of the blood glucose meter 100. That is, one end of the test device 130 is inserted into the entrance / exit 146 of the blood glucose meter 100, and the base end portion of the test device 130 is inserted under the conductive terminal 151 as shown in FIGS. Thereby, the blood glucose level can be measured.
  • blood to be measured is supplied to the blood collection unit 131 provided at the tip of the test device 130.
  • the blood travels through the capillary passage of the test device 130 and moves to the reagent installing portion where the reagent is provided, and a signal corresponding to the amount of glucose is output by the enzyme reaction, and the control unit 105 calculates the blood glucose level based on the signal.
  • the blood glucose level is displayed on the display panel 113.
  • the casing 102 is gripped by four fingers and the palm excluding the thumb, and the thumb is aligned with the input unit 123 and the input is performed.
  • the part 23 is pressed.
  • the grip piece 122 of the housing 102 changes from the state shown in FIG. 7 to the state shown in FIG. 8, so that the test tool 130 can be automatically discharged from the test tool mounting portion 117 to the outside.
  • the claw portion 124 provided at the tip of the grip piece 122 is rotated outward so as to open the entrance / exit 146, and the force pressing the test tool 130 against the guide groove 147 is released.
  • the leaf spring 160 is elastically deformed so that the mountain fold 160b is straight.
  • the pressing portion 160a slides toward the entrance / exit 146 as much as the leaf spring 160 becomes longer in the longitudinal direction, and pushes out the test tool 130.
  • the base end portion of the test device 130 is detached from the conductive terminal 151 and the holding force by the conductive terminal 151 is also released.
  • the test tool 130 becomes free and is automatically ejected by being pushed out by the leaf spring 160.
  • the external force applied to the input unit 123 is released, so that the housing 102 is returned to the original state by the restoring force of the gripping piece 122 and the spring force of the leaf spring 160.
  • the test tool 130 is pushed out using the leaf spring 160.
  • the leaf spring 160 is not provided, if the pressing force of the conductive terminal 151 to the test tool 130 is set to be sufficiently weak, when the holding of the gripping piece 122 by the claw portion 124 is released, the holding weight 122 is turned downward to reduce its own weight. Thus, the test tool 130 can be detached.
  • FIGS. 9 to 12 are diagrams showing a blood glucose meter 200 according to a third embodiment of the present invention.
  • the partial structure of the blood glucose meter 100 according to the second embodiment is changed, and the conductive terminal 251 is elastically deformed by the gripping piece 122 to hold the test device 130. In this configuration, the holding force of the terminal 251 is released.
  • the blood glucose meter 200 according to the third embodiment is different from the blood glucose meter 100 in that the leaf spring 160 is not used and the tip end side of the conductive terminal 251 is locked to the claw portion 124. Therefore, in the blood glucose meter 200, the same parts as those in the second embodiment are denoted by the same reference numerals, and the duplicate description is omitted.
  • the conductive terminal 251 includes a contact part 251 a that is in contact with the test tool 130, a fixed part 251 b that is continuous on one side of the contact part 251 a, and the other side of the contact part 251 a. And a continuous locking portion 251c.
  • the contact portion 251a is formed in a U-shape that protrudes downward.
  • the fixing portion 251b extends in the horizontal direction and is fixed to the terminal block 150.
  • the locking portion 251c is formed in an L shape, is fixed to the back side of the claw portion 124 with a vertical portion raised upward, and follows the rotation of the claw portion 124.
  • Other configurations are the same as those in the above-described embodiment.
  • the casing 102 When the test tool 130 is ejected from the test tool mounting portion 117 after the measurement is completed, for example, the casing 102 is gripped by four fingers and the palm excluding the thumb, and the thumb is aligned with the input unit 123 and the input is performed. The part 23 is pressed. Thereby, since the grip piece 122 of the housing
  • FIG. 11 shows a state in which the test tool 130 is inserted from the entrance / exit 146 and is mounted on the test tool mounting portion 117. At this time, when the test tool 130 is inserted to a predetermined position in the guide groove 147, the contact portions 251 a of the plurality of conductive terminals 251 are pressed against the upper surface of the base end portion of the test tool 130. At this time, the test device 130 is pressed by the claw portion 124 of the grip piece 122.
  • the claw portion 124 provided at the tip of the grip piece 122 is rotated outward so as to open the entrance / exit 146, and the force pressing the test tool 130 against the guide groove 147 is released.
  • the engaging portion 251c of the conductive terminal 251 fixed to the back surface of the claw portion 124 is pulled upward.
  • the entire conductive terminal 251 is lifted, and the contact portion 251 a is pulled away from the test tool 130.
  • the holding force for holding the test tool 130 is released, the test tool 130 becomes free. Therefore, by changing the posture of the blood glucose meter 100 so that the entrance / exit 146 faces downward, the test device 130 can be dropped and discharged by its own weight.
  • the external force applied to the input unit 123 is released, so that the casing 102 returns to the original state by the restoring force of the gripping piece 122 and the spring force of the conductive terminal 251.
  • the test tool can be discharged by giving flexibility to a part of the housing and bending and deforming the flexible part. Therefore, in the conventional apparatus, the number of parts of the discharging member such as a knob is large, but the number of parts can be reduced, and the test tool after measurement can be discharged hygienically.
  • the body fluid component measuring device of the present invention is not limited to the above-described embodiment, and various modifications and changes can be made in the configuration, shape, material, and the like without departing from the configuration of the present invention. It goes without saying that it is possible.
  • blood has been described as a body fluid.
  • the present invention is not limited to this, and may be lymph fluid, spinal fluid, saliva, or the like.
  • glucose blood glucose level
  • glucose blood glucose level
  • examples thereof include cholesterol, uric acid, creatinine, lactic acid, hemoglobin (occult blood).
  • cholesterol may be various alcohols, various sugars, various proteins, various vitamins, various inorganic ions such as sodium, and environmental hormones such as PCB and dioxin.
  • the description has been made on the assumption that the amount of the predetermined component is measured.
  • the property of the predetermined component may be measured, and both the amount and the property of the predetermined component are measured. It may be.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Hematology (AREA)
  • Electrochemistry (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention a pour but de fournir un mécanisme de déchargement d'un outil de test nécessitant des parties telles qu'un levier d'éjection et un ressort à boudin et comprenant par conséquent un grand nombre de pièces et de processus d'assemblage, ce qui est peu économique. Un dispositif de mesure de constituant de fluide corporel (1) comporte un élément de maintien (22) qui est prévu en tant que partie d'un boîtier (2), faisant partie d'une partie de montage d'outil de test (17), et capable de maintenir un outil de test (30) et une partie formant point d'appui (45) qui est disposée sur une partie du boîtier (2) opposée à l'élément de maintien (22) et en contact avec l'élément de maintien (22). De plus, l'élément de maintien (22) est muni d'une partie d'entrée (23) présentant une certaine souplesse, qui est disposée du côté qui est le plus proche d'une extrémité de base que de la partie formant point d'appui (45), et par compression de la partie d'entrée (23), l'élément de maintien (22) est soumise à un pivotement par rapport à la partie formant point d'appui (45), pour ainsi cesser de maintenir l'outil de test (30).
PCT/JP2011/075266 2010-11-05 2011-11-02 Dispositif de mesure de constituants de fluides corporels WO2012060400A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010248389A JP2012095949A (ja) 2010-11-05 2010-11-05 体液成分測定装置
JP2010-248389 2010-11-05

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WO2012060400A1 true WO2012060400A1 (fr) 2012-05-10

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105954270A (zh) * 2016-04-27 2016-09-21 樊福好 一种通过唾液学方法评估葡萄糖代谢的溶液及评估方法
JP2017502281A (ja) * 2013-12-23 2017-01-19 シラグ・ゲーエムベーハー・インターナショナルＣｉｌａｇ ＧＭＢＨ Ｉｎｔｅｒｎａｔｉｏｎａｌ 検査ストリップコネクタの接触保護

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60163248U (ja) * 1984-04-06 1985-10-30 カネボウ株式会社 容器蓋
JP2000171427A (ja) * 1998-09-29 2000-06-23 Omron Corp 試料成分分析システム並びにこのシステムに使用されるセンサチップ及びセンサパック
JP2001233370A (ja) * 2000-02-22 2001-08-28 Tokan Kogyo Co Ltd ２ピース振出容器用キャップ
JP2003114213A (ja) * 2001-10-02 2003-04-18 Matsushita Electric Ind Co Ltd 測定装置
WO2007081001A1 (fr) * 2006-01-13 2007-07-19 Arkray, Inc. Analyseur a ecran
JP2009236790A (ja) * 2008-03-28 2009-10-15 Gunze Ltd センサ着脱構造及び計測表示器
JP2009250696A (ja) * 2008-04-03 2009-10-29 Gunze Ltd センサ着脱構造及び計測表示器
JP2010038661A (ja) * 2008-08-01 2010-02-18 Daisen Sangyo Kk 血糖測定器におけるセンサーチップ除去装置

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60163248U (ja) * 1984-04-06 1985-10-30 カネボウ株式会社 容器蓋
JP2000171427A (ja) * 1998-09-29 2000-06-23 Omron Corp 試料成分分析システム並びにこのシステムに使用されるセンサチップ及びセンサパック
JP2001233370A (ja) * 2000-02-22 2001-08-28 Tokan Kogyo Co Ltd ２ピース振出容器用キャップ
JP2003114213A (ja) * 2001-10-02 2003-04-18 Matsushita Electric Ind Co Ltd 測定装置
WO2007081001A1 (fr) * 2006-01-13 2007-07-19 Arkray, Inc. Analyseur a ecran
JP2009236790A (ja) * 2008-03-28 2009-10-15 Gunze Ltd センサ着脱構造及び計測表示器
JP2009250696A (ja) * 2008-04-03 2009-10-29 Gunze Ltd センサ着脱構造及び計測表示器
JP2010038661A (ja) * 2008-08-01 2010-02-18 Daisen Sangyo Kk 血糖測定器におけるセンサーチップ除去装置

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017502281A (ja) * 2013-12-23 2017-01-19 シラグ・ゲーエムベーハー・インターナショナルＣｉｌａｇ ＧＭＢＨ Ｉｎｔｅｒｎａｔｉｏｎａｌ 検査ストリップコネクタの接触保護
CN105954270A (zh) * 2016-04-27 2016-09-21 樊福好 一种通过唾液学方法评估葡萄糖代谢的溶液及评估方法

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