WO2012004782A2 - Oral remedial mineral replenishment (omr) preparation - Google Patents

Oral remedial mineral replenishment (omr) preparation Download PDF

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Publication number
WO2012004782A2
WO2012004782A2 PCT/IL2011/000419 IL2011000419W WO2012004782A2 WO 2012004782 A2 WO2012004782 A2 WO 2012004782A2 IL 2011000419 W IL2011000419 W IL 2011000419W WO 2012004782 A2 WO2012004782 A2 WO 2012004782A2
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WO
WIPO (PCT)
Prior art keywords
preparation
oral
omr
remedial
mineral
Prior art date
Application number
PCT/IL2011/000419
Other languages
French (fr)
Other versions
WO2012004782A3 (en
Inventor
Sophia Braun
Original Assignee
Sophia Braun
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sophia Braun filed Critical Sophia Braun
Publication of WO2012004782A2 publication Critical patent/WO2012004782A2/en
Publication of WO2012004782A3 publication Critical patent/WO2012004782A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/08—Mineral waters; Sea water
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/358—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/965—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration

Definitions

  • the present invention relates to an oral remedial mineral replenishment (OMR) preparation
  • composition comprising mineral salts in cosmetics, tissue cleansing and for treating psoriasis.
  • the inventor also claims a composition comprising a mineral salt emulsified and dispersed in water, a mineral salt, preferably being a composition of Dead Sea salt, having as active ingredients Magnesium Chloride, Potassium Chloride, Sodium Chloride and water of crystallization and a lipid soluble compound and oils, composition having components present in sufficient quantities to effectively protect the skin tissue within the mouth against an adverse condition and a suitable carrier for permitting formulation as a product for use in the mouth, preferably a toothpaste, cream or mouthwash.
  • the inventor does not claim nor describes any possible of applying the composition of his patent application for replenishment of minerals or for any other purpose but only to protect the skin tissue within the mouth same as it protect the skin tissue of the body to protect it against adverse conditions.
  • the present invention relates to oral remedial mineral replenishment (OMR) preparation, without or along with sundry, inert or active ingredients for oral employment
  • OMR oral remedial mineral replenishment
  • the present patent application is to utilize oral remedial mineral replenishment (OMR) Minerals are important to stay healthy.
  • the body uses minerals for many different applications, including building bones, making hormones and regulating heartbeat.
  • Macro-minerals are minerals the body needs in larger amounts. They include calcium, phosphorus, magnesium, sodium, potassium, chloride and sulfur.
  • the body needs likewise also small amounts of trace minerals. These include iron, manganese, copper, iodine, zinc, cobalt, fluoride, selenium and more minute trace elements. While the best way to get the minerals the body needs is by eating a wide variety of foods, or mineral supplements.
  • the novel Dead Sea preparations I formulated contain only natural Dead Sea substances, that encompass the Dead Sea mineral complex that include trace elements such as Cadmium, Selenium, Molybdenum, Iron, Strontium, Vanadium and Fluorine in such a unique constitution that can consequently be considered as an enriched composite source of mineral components for oral remedial mineral replenishment (OMR) wherein the special and unique Dead Sea minerals can be specially considered as "the building blocks of each human cell" Being important constituents of saliva, gums and teeth (See: Berenholc C, Charles J, Rougereau, Mineral composition of saliva and teeth. Human study, Chir Dent Fr. 1971 6;41(49):23-6.),
  • OMR oral remedial mineral replenishment
  • the unique Dead Sea Mineral composition can act for the replenishment of de- mineralized tissues of the body such as gums, and tooth and can thus strengthen the tissues, which regain their normal activity by the replenished minerals.
  • the Dead Sea minerals replenishment of the tissue encourages the development of invigorated and strengthened tissues, which regain their normal activity.
  • the present invention is based also on my discovery that pure Dead Sea minerals complex composition can be transformed into a wide range of preparations and utilized in preparations such as gels, gums, candies, sprays, and in tablet or an encapsulated forms to be served as food additives, et cetera, and also can be formed into nano particles preparations for better penetration and absorption into the body of the minerals.
  • the oral remedial mineral replenishment (OMR) using the Dead Sea minerals complex has added beneficial effects above and in excess of the mineral replenishment such as prevention of unpleasant mouth smell and antimicrobial inhibitory action more specifically against Gram negative bacteria.
  • OMR oral remedial mineral replenishment
  • the Dead Sea minerals can be utilized for the purpose of this patent on wet as is basis or dried into relatively dried powder
  • Dead Sea Minerals composition About ⁇ 0.2% to >1% of Dead Sea Minerals composition [on dry weight basis] were added to commercial toothpaste, mouth Gel and mouth wash preparations. The preparations were given to be tried by a large number of volunteers over a 2 years period for acceptability tests and general observations. The products were well accepted, compared favourably with the commercial preparations, without added Dead Sea Minerals composition. No ill effects were observed by any of the users.
  • Dead Sea Minerals composition About ⁇ 0.05% to >0.2% of Dead Sea Minerals composition [on dry weight basis] were added to commercial small hand pump spray preparation intended to be used for reduction and prevention of unpleasant mouth smell. The preparations were given to be tried by five volunteers over a month period for acceptability tests and general observations. The product was well accepted, compared favourably with the commercial preparations without added. Dead Sea Minerals composition. No ill effects were observed by any of the users. One of the volunteers that had abrasion wounds in his mouth claimed a quick healing of his cuts after using of the spray that included the Dead Sea Mineral Composition.
  • Dead Sea Minerals composition 0.05% of Dead Sea Minerals composition [on dry weight basis] was incorporated into a "salted" type licorice candy.
  • the candies were given to be tasted by five volunteers for acceptability and comparison to commercial original salted licorice candy without Dead Sea minerals composition.
  • the product was well accepted, compared favourably with the commercial preparations without added Dead Sea Minerals composition. No ill effects were observed by any of the users

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The present invention relates to oral remedial mineral replenishment (OMR) preparation, without or along with sundry, inert or active ingredients for oral employment.

Description

ORAL REMEDIAL MINERAL REPLENISHMENT (OMR) PREPARATION
FIELD OF THE INVENTION
The present invention relates to an oral remedial mineral replenishment (OMR) preparation
BACKGROUND OF THE INVENTION
The topical action of the Dead Sea sourced mineral is well documented in the scientific literature (e.g., Boaz M, Shtendik L, Oron M, Portugal-Cohen M, Kohen R, Biro A, Cernes R, Barnea Z, Maor Z, Katzir Z., A randomized controlled clinical trial comparing the efficacy of dead sea mineral-enriched body lotion versus two types of placebo in the treatment of cutaneous dryness, itching, peeling and tightness in hemodialysis patients (EDIT)., Nephron Clin Pract. 2009, 113(3):cl69-76; Portugal- Cohen M, Soroka Y, Ma'or Z, Oron M, Zioni T, Bregegere FM, Neuman R, Kohen R, Milner Y.. Protective effects of a cream containing Dead Sea minerals against UVB- induced stress in human skin, Exp Dermatol. 2009 Sep;18(9):781-8. as well as in the patent literature (E.g., Israel Patent Application IL122297; US Patent US7687065;).
In US Patent Application US20020012697A to Schwartz, the inventor describes a composition comprising mineral salts in cosmetics, tissue cleansing and for treating psoriasis. The inventor also claims a composition comprising a mineral salt emulsified and dispersed in water, a mineral salt, preferably being a composition of Dead Sea salt, having as active ingredients Magnesium Chloride, Potassium Chloride, Sodium Chloride and water of crystallization and a lipid soluble compound and oils, composition having components present in sufficient quantities to effectively protect the skin tissue within the mouth against an adverse condition and a suitable carrier for permitting formulation as a product for use in the mouth, preferably a toothpaste, cream or mouthwash. The inventor does not claim nor describes any possible of applying the composition of his patent application for replenishment of minerals or for any other purpose but only to protect the skin tissue within the mouth same as it protect the skin tissue of the body to protect it against adverse conditions.
SUMMARY OF THE INVENTION
The present invention relates to oral remedial mineral replenishment (OMR) preparation, without or along with sundry, inert or active ingredients for oral employment
DETAILED DESCRIPTION OF THE INVENTION
The present patent application is to utilize oral remedial mineral replenishment (OMR) Minerals are important to stay healthy. The body uses minerals for many different applications, including building bones, making hormones and regulating heartbeat. There are two kinds of minerals: macro-minerals and trace minerals. Macro-minerals are minerals the body needs in larger amounts. They include calcium, phosphorus, magnesium, sodium, potassium, chloride and sulfur. The body needs likewise also small amounts of trace minerals. These include iron, manganese, copper, iodine, zinc, cobalt, fluoride, selenium and more minute trace elements. While the best way to get the minerals the body needs is by eating a wide variety of foods, or mineral supplements. The novel Dead Sea preparations I formulated contain only natural Dead Sea substances, that encompass the Dead Sea mineral complex that include trace elements such as Cadmium, Selenium, Molybdenum, Iron, Strontium, Vanadium and Fluorine in such a unique constitution that can consequently be considered as an enriched composite source of mineral components for oral remedial mineral replenishment (OMR) wherein the special and unique Dead Sea minerals can be specially considered as "the building blocks of each human cell" Being important constituents of saliva, gums and teeth (See: Berenholc C, Charles J, Rougereau, Mineral composition of saliva and teeth. Human study, Chir Dent Fr. 1971 6;41(49):23-6.),
I noted that as mineral composition of gums and tooth is changed or depleted with age and as a result of various external factors such as diet, diseases, total health conditions etc. The unique Dead Sea Mineral composition can act for the replenishment of de- mineralized tissues of the body such as gums, and tooth and can thus strengthen the tissues, which regain their normal activity by the replenished minerals. The Dead Sea minerals replenishment of the tissue, encourages the development of invigorated and strengthened tissues, which regain their normal activity.
The present invention is based also on my discovery that pure Dead Sea minerals complex composition can be transformed into a wide range of preparations and utilized in preparations such as gels, gums, candies, sprays, and in tablet or an encapsulated forms to be served as food additives, et cetera, and also can be formed into nano particles preparations for better penetration and absorption into the body of the minerals. Likewise I noted that the oral remedial mineral replenishment (OMR) using the Dead Sea minerals complex has added beneficial effects above and in excess of the mineral replenishment such as prevention of unpleasant mouth smell and antimicrobial inhibitory action more specifically against Gram negative bacteria. I also have also found out that the Dead Sea minerals can be utilized for the purpose of this patent on wet as is basis or dried into relatively dried powder
The present invention will be further illustrated and clarified by the following not limiting.
EXAMPLE I
About <0.2% to >1% of Dead Sea Minerals composition [on dry weight basis] were added to commercial toothpaste, mouth Gel and mouth wash preparations. The preparations were given to be tried by a large number of volunteers over a 2 years period for acceptability tests and general observations. The products were well accepted, compared favourably with the commercial preparations, without added Dead Sea Minerals composition. No ill effects were observed by any of the users.
EXAMPLE II
About <0.05% to >0.2% of Dead Sea Minerals composition [on dry weight basis] were added to commercial small hand pump spray preparation intended to be used for reduction and prevention of unpleasant mouth smell. The preparations were given to be tried by five volunteers over a month period for acceptability tests and general observations. The product was well accepted, compared favourably with the commercial preparations without added. Dead Sea Minerals composition. No ill effects were observed by any of the users. One of the volunteers that had abrasion wounds in his mouth claimed a quick healing of his cuts after using of the spray that included the Dead Sea Mineral Composition.
EXAMPLE III
0.05% of Dead Sea Minerals composition [on dry weight basis] was incorporated into a "salted" type licorice candy. The candies were given to be tasted by five volunteers for acceptability and comparison to commercial original salted licorice candy without Dead Sea minerals composition. The product was well accepted, compared favourably with the commercial preparations without added Dead Sea Minerals composition. No ill effects were observed by any of the users
There is an almost infinite number of variations and modes to provide for the Dead Sea oral remedial mineral replenishment preparation (OMR), in a different dry matter concentrations, or as compounded preparations to provide an accessible source of the oral remedial mineral replenishment preparation (OMR), This without departing from the spirit of the invention, on condition that the fundamental principle of the employment of Dead Sea Mineral composition as set forth above is followed.

Claims

1. Oral remedial mineral replenishment preparation (OMR) based on the Dead Sea minerals.
2. Oral remedial mineral replenishment preparation (OMR) as in claims 1 and 2 wherein the preparation is in a form of gels, gums, candies and sprays.
3. Oral remedial mineral replenishment preparation (OMR) as in claims 1 and 2 wherein the preparation is in an encapsulated form or tablet food supplements.
4. Oral remedial mineral replenishment preparation (OMR) as in claims 1, 2 and 3, wherein the preparation is formed into nano particles preparations.
5. Oral remedial mineral replenishment preparation (OMR) as in claims 1, 2, 3 4, and 5 wherein the preparation is used in addition for prevention of unpleasant mouth smell.
6. Oral remedial mineral replenishment preparation (OMR) as in claims 1, 2, 3 4, and 5 wherein the preparation is used in addition as an antimicrobial composition.
7. Oral remedial mineral replenishment preparation (OMR) prepared as in any of the preceding claims, wherein the Dead Sea mineral composition is used in a as is wet basis, or as a partially semi-dehydrated form or as a substantially dry powder.
8. Preparation of an Oral remedial mineral replenishment preparation (OMR) essentially prepared as any of the preceding claims.
PCT/IL2011/000419 2010-07-05 2011-05-31 Oral remedial mineral replenishment (omr) preparation WO2012004782A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL206804A IL206804A0 (en) 2010-07-05 2010-07-05 Oral remedial mineral replenishment (omr) preparation
IL206804 2010-07-05

Publications (2)

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WO2012004782A2 true WO2012004782A2 (en) 2012-01-12
WO2012004782A3 WO2012004782A3 (en) 2012-03-29

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180360735A1 (en) * 2016-12-21 2018-12-20 Mge Holdings Llc Oral Care Products and Methods
US10813877B2 (en) * 2016-12-21 2020-10-27 Oral Health Innovations, LLC Oral care products and methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020012697A1 (en) 1998-01-26 2002-01-31 Sam Schwartz Cosmetic and tissue cleansing and moisturizing composition
US7687065B1 (en) 1997-12-28 2010-03-30 Dead Sea Laboraories, Ltd. Gel composition for skin care and protection and a method for preparation thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3008171A1 (en) * 1980-03-04 1981-09-10 Biolabor Walter Brachmann, 2800 Bremen Nutritional table salt prepn. - by mixing carnallite-contg. dead sea water concentrate with rock salt or sodium chloride
DE19914646A1 (en) * 1999-03-31 2000-10-05 Kapitz Carl Heinz Combination of active agents for humans and animals, e.g. for medicinal, nutritional or cosmetic use, comprises a colostral milk product or extract, minerals and plant components or extracts
US20040258712A1 (en) * 2003-05-19 2004-12-23 Amazon Biotech Inc. Herbal composition containing sea salt

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7687065B1 (en) 1997-12-28 2010-03-30 Dead Sea Laboraories, Ltd. Gel composition for skin care and protection and a method for preparation thereof
US20020012697A1 (en) 1998-01-26 2002-01-31 Sam Schwartz Cosmetic and tissue cleansing and moisturizing composition

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BERENHOLC C, CHARLES J: "Rougereau, Mineral composition of saliva and teeth", HUMAN STUDY, CHIR DENT FR., vol. 41, no. 49, 1971, pages 23 - 6
BOAZ M, SHTENDIK L, ORON M, PORTUGAL-COHEN M, KOHEN R, BIRO A, CERNES R, BARNEA Z, MAOR Z, KATZIR Z.: "A randomized controlled clinical trial comparing the efficacy of dead sea mineral-enriched body lotion versus two types of placebo in the treatment of cutaneous dryness, itching, peeling and tightness in hemodialysis patients (EDIT", NEPHRON CLIN PRACT., vol. 113, no. 3, 2009, pages 169 - 76
PORTUGAL-COHEN M, SOROKA Y, MA'OR Z, ORON M, ZIONI T, BREGEGERE FM, NEUMAN R, KOHEN R, MILNER Y.: "Protective effects of a cream containing Dead Sea minerals against UVB- induced stress in human skin", EXP DERMATOL., vol. 18, no. 9, September 2009 (2009-09-01), pages 781 - 8

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180360735A1 (en) * 2016-12-21 2018-12-20 Mge Holdings Llc Oral Care Products and Methods
US10813877B2 (en) * 2016-12-21 2020-10-27 Oral Health Innovations, LLC Oral care products and methods

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Publication number Publication date
IL206804A0 (en) 2010-12-30
WO2012004782A3 (en) 2012-03-29

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