WO2011142588A3 - 피부결함의 완화 또는 치료를 위한 자가피부세포치료제의 제조방법 - Google Patents

피부결함의 완화 또는 치료를 위한 자가피부세포치료제의 제조방법 Download PDF

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Publication number
WO2011142588A3
WO2011142588A3 PCT/KR2011/003474 KR2011003474W WO2011142588A3 WO 2011142588 A3 WO2011142588 A3 WO 2011142588A3 KR 2011003474 W KR2011003474 W KR 2011003474W WO 2011142588 A3 WO2011142588 A3 WO 2011142588A3
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Prior art keywords
skin
alleviating
treating
preparing
present
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PCT/KR2011/003474
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English (en)
French (fr)
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WO2011142588A2 (ko
WO2011142588A9 (ko
Inventor
이정숙
정효선
이정희
윤천재
손태식
김경식
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(주)메디컬그룹베스티안
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Priority to CN2011800228845A priority Critical patent/CN103037871A/zh
Publication of WO2011142588A2 publication Critical patent/WO2011142588A2/ko
Publication of WO2011142588A3 publication Critical patent/WO2011142588A3/ko
Publication of WO2011142588A9 publication Critical patent/WO2011142588A9/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

본 발명은 피부 결함의 완화 또는 치료를 위한 자가피부세포치료제의 제조방법에 관한 것이다. 본 발명에 따른 자가피부세포를 이용한, 피부 결함의 완화 또는 치료하기 위한 세포치료제의 제조방법은 주체로부터 정상 피부 조직을 획득하는 단계와; 상기 획득한 조직을 세포단위로 분쇄하는 단계와; 상기 분쇄 후 조직 파쇄물로부터 각질형성세포, 멜라닌색소세포 및 섬유세포를 포함하는 피부세포군을 획득하는 단계를 포함하는 것을 특징으로 하는 세포치료제의 제조방법을 제공한다. 이에 의하여, 기존 세포치료제 제조방법과는 달리, 효소처리 및/또는 배양 단계가 배제되어 상당히 간편하고 빠른 시간 내에 제조하여 바로 환부에 적용할 수 있는 효과를 갖는다.
PCT/KR2011/003474 2010-05-11 2011-05-11 피부결함의 완화 또는 치료를 위한 자가피부세포치료제의 제조방법 WO2011142588A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011800228845A CN103037871A (zh) 2010-05-11 2011-05-11 用于缓解或治疗皮肤缺损的自体皮肤细胞治疗剂的制备方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2010-0044179 2010-05-11
KR20100044179 2010-05-11

Publications (3)

Publication Number Publication Date
WO2011142588A2 WO2011142588A2 (ko) 2011-11-17
WO2011142588A3 true WO2011142588A3 (ko) 2012-04-19
WO2011142588A9 WO2011142588A9 (ko) 2012-06-07

Family

ID=44914822

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/003474 WO2011142588A2 (ko) 2010-05-11 2011-05-11 피부결함의 완화 또는 치료를 위한 자가피부세포치료제의 제조방법

Country Status (3)

Country Link
KR (1) KR101328561B1 (ko)
CN (1) CN103037871A (ko)
WO (1) WO2011142588A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104611289A (zh) * 2015-01-13 2015-05-13 广州赛奕德生物技术有限公司 自体表皮细胞和成纤维细胞同时制备方法及其生物美容产品
CN107961061A (zh) * 2017-12-19 2018-04-27 济南磐升生物技术有限公司 一种自体皮肤创伤治疗仪
KR102427018B1 (ko) * 2019-06-11 2022-07-29 재단법인 베스티안재단 피부치료제의 제조방법 및 이로부터 얻어지는 피부치료제

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7641898B2 (en) * 2003-03-21 2010-01-05 Materials Evolution And Development Usa, Inc. Keratinocyte-fibrocyte concomitant grafting for wound healing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8394371B2 (en) 2002-02-11 2013-03-12 Neocutis Sa Compositions for the treatment of skin conditions, disorders or diseases and methods of making and using the same
KR100806695B1 (ko) * 2005-11-25 2008-02-27 주식회사 엠씨티티 색소화 질환 치료용 세포치료 약제학적 조성물

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7641898B2 (en) * 2003-03-21 2010-01-05 Materials Evolution And Development Usa, Inc. Keratinocyte-fibrocyte concomitant grafting for wound healing

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CURRIE,L.J.: "A comparison of keratinocyte cell sprays with and without fibrin glue.", BURNS., vol. 29, 2003, pages 677 - 685, XP055098899, DOI: doi:10.1016/S0305-4179(03)00155-4 *
GRANT,I. ET AL.: "The co-application of sprayed cultured autologous keratinocytes and autologous fibrin sealant in a porcine wound model.", BRITISH JOURNAL OF PLASTIC SURGERY., vol. 55, 2002, pages 219 - 227, XP005316172, DOI: doi:10.1054/bjps.2002.3810 *
SON, YEON SUK ET AL.: "Autologous cell therapy spry and Artificial skin for Bioscreeing.", NEWS AND INFORMATION FOR CHEMICAL ENGINEERS, vol. 26, no. 2, 2008, pages 139 - 145 *
WOOD,F.M. ET AL.: "The use of a non-cultured autologous cell suspension and Integra dermal regeneration template to repair full-thickness skin wounds in a porcine model: A one-step process", BUMS., vol. 33, 2007, pages 693 - 700, XP022202567, DOI: doi:10.1016/j.burns.2006.10.388 *
ZWEIFEL,C.J. ET AL.: "Initial experiences using non-cultured autologous keratinocytes suspension for burn wound closure.", JOURNAL OF PLASTIC, RECONSTRUCTIVE & AESTHETIC SURGERY., vol. 61, 2008, pages E1 - E4 *

Also Published As

Publication number Publication date
KR20110124722A (ko) 2011-11-17
WO2011142588A2 (ko) 2011-11-17
KR101328561B1 (ko) 2013-11-13
WO2011142588A9 (ko) 2012-06-07
CN103037871A (zh) 2013-04-10

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