WO2011140006A1 - Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen - Google Patents

Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen Download PDF

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Publication number
WO2011140006A1
WO2011140006A1 PCT/US2011/034882 US2011034882W WO2011140006A1 WO 2011140006 A1 WO2011140006 A1 WO 2011140006A1 US 2011034882 W US2011034882 W US 2011034882W WO 2011140006 A1 WO2011140006 A1 WO 2011140006A1
Authority
WO
WIPO (PCT)
Prior art keywords
therapeutic agent
lumen
tubular prosthesis
cylindrical
balloon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/034882
Other languages
English (en)
French (fr)
Inventor
Matthew David Cambronne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiovascular Systems Inc
Original Assignee
Cardiovascular Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiovascular Systems Inc filed Critical Cardiovascular Systems Inc
Priority to AU2011248375A priority Critical patent/AU2011248375B2/en
Priority to JP2013509159A priority patent/JP5866344B2/ja
Priority to HK13104402.9A priority patent/HK1176895B/xx
Priority to CA2796187A priority patent/CA2796187A1/en
Priority to EP11778130A priority patent/EP2566415A1/en
Priority to CN201180021265.4A priority patent/CN102858399B/zh
Publication of WO2011140006A1 publication Critical patent/WO2011140006A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/06—Body-piercing guide needles or the like
    • A61M25/0662—Guide tubes
    • A61M2025/0681—Systems with catheter and outer tubing, e.g. sheath, sleeve or guide tube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes

Definitions

  • Atherosclerosis is characterized by the buildup of fatty deposits (atheromas) in the intimal layer (under the endothelium) of a patient's blood vessels. Very often over time, what initially is deposited as relatively soft, cholesterol-rich atheromatous material hardens into a calcified atherosclerotic plaque. Such atheromas restrict the flow of blood, and therefore often are referred to as stenotic lesions or stenoses, the blocking material being referred to as stenotic material. If left untreated, such stenoses can cause angina, hypertension, myocardial infarction, strokes, leg pain and the like.
  • U.S. Pat. No. 5,314,438 discloses another atherectomy device having a drive shaft with a section of the drive shaft having an enlarged diameter, at least a segment of this enlarged surface being covered with an abrasive material to define an abrasive segment of the drive shaft.
  • the abrasive segment When rotated at high speeds, the abrasive segment is capable of removing stenotic tissue from an artery.
  • this atherectomy device possesses certain advantages over the Auth device due to its flexibility, it also is capable only of opening an artery to a diameter about equal to the diameter of the enlarged abrading surface of the drive shaft since the device is not eccentric in nature.
  • the formulation can contain less than 1 % of the drug.
  • the material may, in addition to being biodegradable, also be bioabsorbable as is known in the art.
  • preferred time ranges for the degradation of the tubular prosthesis 10 when inserted in the biological lumen include a preferred range of about 1 week to about 6 months, a more preferred range of about 2 weeks to about 6 months, a most preferred range of about 2 weeks to about 4 months.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PCT/US2011/034882 2010-05-03 2011-05-03 Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen Ceased WO2011140006A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU2011248375A AU2011248375B2 (en) 2010-05-03 2011-05-03 Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen
JP2013509159A JP5866344B2 (ja) 2010-05-03 2011-05-03 生物学的管腔に治療物質を局所適用するための治療剤送達システムおよび方法
HK13104402.9A HK1176895B (en) 2010-05-03 2011-05-03 Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen
CA2796187A CA2796187A1 (en) 2010-05-03 2011-05-03 Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen
EP11778130A EP2566415A1 (en) 2010-05-03 2011-05-03 Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen
CN201180021265.4A CN102858399B (zh) 2010-05-03 2011-05-03 治疗药物输送系统及向生物管腔局部施用治疗药物的方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33061710P 2010-05-03 2010-05-03
US61/330,617 2010-05-03
US13/098,695 2011-05-02
US13/098,695 US9114235B2 (en) 2010-05-03 2011-05-02 Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen

Publications (1)

Publication Number Publication Date
WO2011140006A1 true WO2011140006A1 (en) 2011-11-10

Family

ID=44904015

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/034882 Ceased WO2011140006A1 (en) 2010-05-03 2011-05-03 Therapeutic agent delivery system and method for localized application of therapeutic substances to a biological lumen

Country Status (7)

Country Link
US (1) US9114235B2 (enExample)
EP (1) EP2566415A1 (enExample)
JP (1) JP5866344B2 (enExample)
CN (1) CN102858399B (enExample)
AU (1) AU2011248375B2 (enExample)
CA (1) CA2796187A1 (enExample)
WO (1) WO2011140006A1 (enExample)

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US10898700B2 (en) 2012-10-26 2021-01-26 Urotronic, Inc. Balloon catheters for body lumens
EP2911711A4 (en) 2012-10-26 2016-05-25 Urotronic Inc MEDICATION-COATED BALLOON CATHETERS FOR NON-VASCULAR STRUCTURES
US11938287B2 (en) 2012-10-26 2024-03-26 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US10881839B2 (en) 2012-10-26 2021-01-05 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US10850076B2 (en) 2012-10-26 2020-12-01 Urotronic, Inc. Balloon catheters for body lumens
US11504450B2 (en) 2012-10-26 2022-11-22 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US10806830B2 (en) 2012-10-26 2020-10-20 Urotronic, Inc. Drug-coated balloon catheters for body lumens
WO2015138247A1 (en) 2014-03-12 2015-09-17 Boston Scientific Limited Infusion lubricated atherectomy catheter
US10405878B2 (en) 2014-07-25 2019-09-10 Boston Scientific Scimed, Inc. Rotatable medical device
US10405879B2 (en) 2014-12-04 2019-09-10 Boston Scientific Scimed, Inc. Rotatable medical device
EP3285820A4 (en) 2015-04-24 2018-12-12 Urotronic, Inc. Drug coated balloon catheters for nonvascular strictures
US11904072B2 (en) 2015-04-24 2024-02-20 Urotronic, Inc. Drug coated balloon catheters for nonvascular strictures
CN107303406A (zh) * 2016-04-21 2017-10-31 青岛智辰生物科技有限公司 一种球囊扩张导管
WO2018204700A1 (en) 2017-05-03 2018-11-08 Medtronic Vascular, Inc. Tissue-removing catheter with guidewire isolation liner
US11690645B2 (en) 2017-05-03 2023-07-04 Medtronic Vascular, Inc. Tissue-removing catheter
EP4434477A3 (en) 2018-11-16 2024-11-27 Medtronic Vascular Inc. Tissue-removing catheter
EP3927410A1 (en) 2019-02-22 2021-12-29 Urotronic, Inc. Drug-coated balloon catheters for body lumens
US11819236B2 (en) 2019-05-17 2023-11-21 Medtronic Vascular, Inc. Tissue-removing catheter
JP2022551512A (ja) * 2019-10-10 2022-12-09 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 細胞カプセル化デバイス
CN112409922A (zh) * 2020-11-19 2021-02-26 广东电网有限责任公司电力科学研究院 一种类微脉管及其制备方法、缓释抗菌剂和抗菌涂料

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US20060287709A1 (en) * 2002-11-13 2006-12-21 Advanced Cardiovascular Systems, Inc. Drug-eluting stent and methods of making the same
US20100023108A1 (en) * 2004-03-19 2010-01-28 Toner John L Multiple Drug Delivery From A Balloon And A Prosthesis

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US20060271168A1 (en) * 2002-10-30 2006-11-30 Klaus Kleine Degradable medical device
US20060287709A1 (en) * 2002-11-13 2006-12-21 Advanced Cardiovascular Systems, Inc. Drug-eluting stent and methods of making the same
US20100023108A1 (en) * 2004-03-19 2010-01-28 Toner John L Multiple Drug Delivery From A Balloon And A Prosthesis

Also Published As

Publication number Publication date
JP2013525072A (ja) 2013-06-20
US20120109105A1 (en) 2012-05-03
EP2566415A1 (en) 2013-03-13
CN102858399A (zh) 2013-01-02
AU2011248375A1 (en) 2012-10-25
CN102858399B (zh) 2015-07-08
AU2011248375B2 (en) 2015-08-06
JP5866344B2 (ja) 2016-02-17
US9114235B2 (en) 2015-08-25
CA2796187A1 (en) 2011-11-10
HK1176895A1 (en) 2013-08-09

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