WO2011129567A4 - Récipient pour le stockage de gaz, procédé de charge d'hydrogène, et appareil de charge d'hydrogène - Google Patents

Récipient pour le stockage de gaz, procédé de charge d'hydrogène, et appareil de charge d'hydrogène Download PDF

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Publication number
WO2011129567A4
WO2011129567A4 PCT/KR2011/002536 KR2011002536W WO2011129567A4 WO 2011129567 A4 WO2011129567 A4 WO 2011129567A4 KR 2011002536 W KR2011002536 W KR 2011002536W WO 2011129567 A4 WO2011129567 A4 WO 2011129567A4
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WIPO (PCT)
Prior art keywords
hydrogen
container
gas
candy
oil
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PCT/KR2011/002536
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English (en)
Korean (ko)
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WO2011129567A2 (fr
WO2011129567A3 (fr
Inventor
조건환
Original Assignee
Cho Keon-Hwan
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Priority claimed from KR20100034945A external-priority patent/KR101237957B1/ko
Priority claimed from KR20100127087A external-priority patent/KR101311697B1/ko
Application filed by Cho Keon-Hwan filed Critical Cho Keon-Hwan
Publication of WO2011129567A2 publication Critical patent/WO2011129567A2/fr
Publication of WO2011129567A3 publication Critical patent/WO2011129567A3/fr
Publication of WO2011129567A4 publication Critical patent/WO2011129567A4/fr

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
    • A23G3/56—Products with edible or inedible supports, e.g. lollipops
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Definitions

  • the present invention relates to a gas storage container, a hydrogen sealing method, and a hydrogen filling apparatus. More particularly, the present invention relates to a technique for directly supplying hydrogen into a container filled with hydrogen, candy generating hydrogen, or the like.
  • Capsules are widely used for the storage and packaging of health foods or medicines taken orally, and they can be called hard capsules and soft capsules depending on the capsule material, and are used for storing powder or liquid. Capsule containers are often not strictly confidential, depending on what is stored.
  • Hard candy may be used as a packaging container for oral health food, medicines or preference foods.
  • a saccharide system in which hydrogen is added is used as a composition (syrup) of a carbohydrate as a method for assisting micro-crystallization (crystallization of crystalline polyols) It is introduced in publication No. 0163252.
  • the soft capsule preparation is prepared by mixing a main ingredient and an excipient or by solubilizing with a surfactant to prepare a chargeable content liquid.
  • the thickness of the film is generally adjusted to 0.60 to 0.80 mm when the contents are filled, And a drug delivery system that is put into the oral cavity and absorbed from the stomach or intestines is generally used.
  • the soft capsules are mainly made of gelatin. After the melted gelatin is put in a spreader box, the melted gelatin is spread on the rotary drum roller to a desired thickness in a spreader box in the form of a sheet, To form capsules.
  • the patent publication No. 10-0647034 published on Nov. 23, 2006 discloses " soft capsules and a manufacturing method thereof ", and discloses a device for manufacturing a soft capsule recently disclosed, 20-0445951 There is design.
  • the device of this invention comprises a sheet forming unit having a spreader box and a cooling drum, a capsule forming unit having a die roller and a stock solution discharge nozzle, and a capsule recovering unit for recovering the molded capsule, wherein the gelatin soft capsule
  • the melted gelatin is put into a spreader box, and melted gelatin is spread on the rotary drum roller in a desired thickness.
  • the melted gelatin is spread in the form of a sheet.
  • the gelatin sheet is cut and bonded while passing through a pair of die rollers, To prepare a capsule.
  • These conventional soft capsules have mainly been used as containers for packaging solid or liquid contents and have also been used to facilitate oral ingestion by packaging such solid powders or liquids (e.g., omega-3).
  • a hydrogen-rich water supply cold water purifier for generating hydrogen by attaching a bubble generator and a ceramic rod to a conventional water purifier is disclosed in Korean Patent Publication No. 10-0552003.
  • Hydrogen reduction and bubble generator using electrolysis can not be used in a place where no water purifier is installed and power supply is required. Therefore, there is a difficulty in being restricted in terms of range of use and availability, and calcium in the ceramic rod is generated by reaction with water Hydrogen-rich water generators that produce hydrogen-rich water by reacting magnesium particles to beverage water are limited in their ability to dissolve metal hydroxides, which require periodic application of Zirconium (hydrogen stick) with magnesium particles in specially prepared PET bottles There is a difficulty in sanitary management of PET bottles and Zaruche, and there are difficulties in the place and time constrained to drink hydrogen-rich water.
  • the present invention is directed to a method for packaging a gas, a gas storage container, and a technique for transporting the gas into the human body or generating gas in the human body.
  • the present invention seeks to provide a gas storage container, a method of manufacturing the same, and a method of packaging the contents in a capsule.
  • the present invention provides a container for gas storage, which is a container for gas storage, in which a container of capsules is melted by water to gradually degrade the airtightness so that the gas in the container gradually leaks out.
  • the present invention relates to a capsule for storing a hydrogen gas, a method for producing the capsule, and a method for packing hydrogen into a capsule in order to release hydrogen gas from the container after the hydrogen gas is packed in a sealed container and orally administered after a certain period of time Method.
  • the present invention seeks to provide a method for producing a hydrogen hard candy in the form of a capsule as a container for storing hydrogen.
  • the present invention relates to a method of manufacturing a gas storage container capable of reducing the amount of heat consumed as compared with a consumed hydrogen gas by using a material having a smaller calorific value as a material of the capsule and using a soft coating material to increase storage capacity per container, To provide a method of filling and sealing hydrogen in a gas storage container.
  • the present invention aims to provide a means and a method for directly packing hydrogen and transporting it to the intestines by using the hydrogen generating material and the material of the hydrogen generating material which cause the hydrogen gas to be generated directly in the body using the characteristics of the small saccharides or polysaccharides.
  • the present invention relates to a method for selecting a substance extracted from a small amount of sugars, polysaccharides and edible spices present in edible crops and adding them appropriately to a candy material in order to produce beneficial hydrogen gas by fermentation by germs in a large intestine by human ingestion, I would like to offer a candy material.
  • the present invention relates to a candy container material for storing hydrogen gas, which is prepared by appropriately adding substances selected from small sugars, polysaccharides and edible spices, which have been taken by humans and fermented by bacteria in the large intestine to generate hydrogen gas,
  • the present invention provides a container-type hydrogen storage container and a method of manufacturing the same, in which the hydrogen gas stored in the container and the hydrogen gas generated in the candy container material are combined to produce more hydrogen generating effect.
  • the present invention is made of polyethylene water jackets containing water or refractory antifreeze for packaging or safely transporting or storing hydrogen storage containers or hydrogen-producing candy containers, and when melted at temperatures above 120 degrees Celsius, they are melted to release water or refractory antifreeze To provide a packaging material.
  • the present invention is a small container made of a material that does not pass through a storing gas but dissolves in contact with water and has a sealed void space therein for storing the gas. Gradually destroyed, causing the gas inside to leak out.
  • the gas storage container is capable of withstanding atmospheric pressure changes in consideration of the pressure applied to the inside and outside of the cylinder and has an outer diameter of 5 to 10 mm, preferably 8 mm, an outer cylinder length of 8 to 20 mm, preferably 14 mm,
  • the total length of the containers 2 including the end plates 10 at both ends is 10 to 25 mm, preferably 22 mm.
  • the container of the present invention can be produced by mixing a mixture of carbohydrate syrup such as starch, maltitol, mannitol, sorbitol, isomalt, xylitol and the like, sugar such as soft candy, amorphous hard candy, ) mixture, one or will the composition in the above mixture, if necessary, gelatin, glycerin, iron (ferrous fumarate), vitamin C, vitamin E, polyphenols (polyphenol), carotene (carotene), a calcium, a selected, etc., etc. of Add the above additives.
  • the gas to be stored in the container is hydrogen gas, and its purity is 99.999% or more, preferably 99.99999% or more.
  • the present invention relates to a method of filling hydrogen into an ultra-small container and sealing the container by using a container material that dissolves heat, a hydrogen-filled nozzle having a volume as large as a space to be filled with hydrogen, A thermocompression band is attached to a portion excluding a length corresponding to a predetermined hydrogen filling space, air in a space inside the temporary container is drawn out through a hydrogen filling nozzle, Sealing the temporary container inlet by tightening the band and applying heat to the thermocompression band and retracting the hydrogen fill nozzle to the end of the thermocompression band, And a step of finishing the processed portion.
  • At least one of the saccharides such as sugar, maltose, and sweet potato, a mixture of carbohydrate syrup mixture of starch, maltitol, mannitol, sorbitol, isomalt, xylitol, etc. and polyols is selected as the container material
  • one or more additives selected from gelatin, glycerin, ferrous fumarate, vitamin C, vitamin E, polyphenol, carotene, calcium, calcium hydride and the like are optionally added to make a mass, It is good to put it in a mold.
  • the chamber material in a well the confidentiality of at least air, low in calories and well thermal deformation at the time to be squeezed by applying heat, and a glass transition temperature of the mixture or selection of 38 o C or higher sugar with a water content of at least 3% ,
  • the purity of the hydrogen gas filled in the container is preferably 99.999% or more.
  • the apparatus of the present invention comprises n hydrogen filling nozzles and auxiliary devices to be inserted into a temporary container formed in a mold and includes a hydrogen filling nozzle portion for pumping the inside of the temporary container during the hydrogen filling period into vacuum, A hydrogen purging type pipe connected to the hydrogen filling nozzle portion and connected to the hydrogen gas filled passage and the hydrogen gas passage, a vacuum pumping portion connected to the hydrogen filled mesh type pipe for pumping the inside of the temporary container into a vacuum state, A hydrogen gas supply unit connected to the pipe, for supplying hydrogen gas, controlling the flow rate and pressure, and a nitrogen gas supply unit connected to the hydrogen-filled silencer pipe for purge and safety of the hydrogen gas filling system.
  • the present invention also relates to a gas storage container having an inner space larger than the volume of the gas storage container outside the gas storage container and further containing a hard capsule for receiving and sealing the gas storage container therein,
  • the stored hydrogen gas is firstly kept at an airtightness of the hydrogen gas by the atmospheric pressure of the outside, the airtightness of the hydrogen gas is compensated for by the hard capsule by the hard capsule, and the pressure change is buffered by the space between the gas storage container and the hard capsule .
  • the hydrogen gas is stored in a microcontainer so that it can be put into the oral cavity, thereby providing a hydrogen capsule which can be inserted deeply into the digestive life of living organisms.
  • the flexible film storage container is gas sealed in a container made of a soft film which is soluble in water but not soluble in organic solvent.
  • the gas is hydrogen
  • the container is formed in consideration of a pressure change of atmospheric pressure, and the thickness of the cooled and dried coating is 0.7 to 1.0 mm, the thickness of the joint is 0.6 to 0.95 mm, and the thickness of the restored nozzle insertion port is 0.7 to 1.0 mm .
  • the material forming the soft coating may be selected from the group consisting of sorbitol, sorbitan, or sorbitol series, polyglycitol syrup, sucrose, mannitol, xylitol, maltose, reduced maltose syrup , Maltitol, and polyethylene glycol, and one or more selected from the group consisting of purified water, black iron oxide, and red iron oxide is used as a base of the coating film.
  • the gas storage container contains hydrogen gas in an amount of 70 to 97% by volume, and the content of hydrogen gas is in the range of 70 to 97% by volume, and is selected from soybean oil, safflower oil, refined fish oil, refined oil, sesame oil, Make the selected one or more components 3 to 30% by volume.
  • the method of the present invention is a method of filling and sealing hydrogen gas in a gas storage container made of a soft film, comprising the steps of: preparing a temporary container of a soft coating film in which a lubricant is enclosed and sealed; And injecting hydrogen gas; withdrawing the hydrogen filling nozzle out of the container; and sealing the nozzle insertion port opened in the temporary container by the hydrogen filling nozzle with the grouting material.
  • the hydrogen-containing nozzle has a sharp tip like a needle, and leaves 3 ⁇ 30% of the oil when the oil in the temporary container is drawn out.
  • the present invention is a hydrogen-producing candy produced by mixing a substance that produces hydrogen gas in the large intestine by a colon bacteria flora with candy at a ratio of 30% to 70% to candy.
  • the candy of the present invention is at least one selected from lactose, lactoose, raffinose, stachyose, bavascoose, curcumin, capsaicin, inulin, gingerol, alicin, .
  • the present invention relates to a candy container comprising a material for producing hydrogen gas in the large intestine by a group of intestinal bacteria and candy, the candy container being made by mixing the substance to 30% or more with respect to candy, It is a hydrogen-producing candy container.
  • the present invention relates to a process for producing hydrogen-producing candy, which comprises boiling a mixture of at least one of polyols such as millitol, mannitol, sorbitol, isomalt and xylitol at 150 to 200 ° C under atmospheric pressure to evaporate most of the water
  • polyols such as millitol, mannitol, sorbitol, isomalt and xylitol
  • the present invention also provides a method for producing a hydrogen-producing candy container, comprising the steps of boiling a mixture to evaporate most of the water to form massecuites in which the water of candy is removed; Adding at least one selected from lactose, lactolose, raffinose, stachyose, bavascoose, curcumin, capsaicin, inulin, gingerol, alicin, asparagine, glutenin and the like to the meat sacget; Molding the candy container by molding or injection molding the saclet, and filling and sealing the formed candy container with hydrogen gas.
  • the present invention consists of a thin cushioned polyethylene water jacket containing water or a refractory antifreeze for packaging and safely transporting or storing a hydrogen-producing candy can container, which melts to release water or refractory antifreeze when it is above 120 degrees Celsius will be.
  • the gas can be filled, stored and transported in an ultra-small container having a sealed hollow space inside and hermetically broken by water contact.
  • the hydrogen storage container of the present invention When the hydrogen storage container of the present invention is orally administered together with general drinking water or dissolved in drinking water, it is possible to supply hydrogen gas to the inside of the living body.
  • the present invention is free from the constraints of time and place where active hydrogen can be ingested.
  • the use of the hydrogen storage container manufacturing method and apparatus of the present invention enables gas other than hydrogen to be packaged in a very small size.
  • the hydrogen storage container is manufactured by the apparatus and the method of the present invention, it is possible to easily control the intake amount of hydrogen gas, appropriately adjust the supply of active hydrogen to the generated active oxygen amount, can do.
  • the container for storing a soft film of the present invention When the container for storing a soft film of the present invention is used as a hydrogen storage container, hydrogen gas storage capacity per container is remarkably improved, stretchability corresponding to an external temperature is improved, and caloric intake is reduced.
  • the present invention can expand the amount of hydrogen which is harmless to the human body to be supplied to the body without using the conventional method of consuming the fired metal or the gold water-soluble material to generate metal hydroxide in the body.
  • the present invention is superior in terms of human safety to ingesting calcium hydrogen carbonate calcined calcium carbonate.
  • the present invention can solve time and space constraints and concentration deterioration that can not be solved by electrolytic reduced water, poured hydrogen water, and hydrogen-rich water produced by sticks.
  • the present invention can increase the efficiency of consuming human hydrogen by making the hydrogen supply capacity larger than that of a micro container using candy having a function of storing hydrogen or a micro container using a soft film.
  • the capsule can be used in capsule unit when administered to the inside of a human body.
  • the packing material of the hydrogen-producing candy container of the present invention has an effect of preventing the hydrogen storage containers from being exposed to fire or from being accidentally exploded even when the stored hydrogen is leaked.
  • FIG. 1A and 1B are cross-sectional views of a hydrogen storage container accommodated in a gas storage container / hard capsule according to an embodiment of the present invention.
  • Figures 2a), b), c), d), and e) illustrate a process for forming a gas container and filling the hydrogen gas according to an embodiment of the present invention.
  • FIGS 3a), b) are schematic diagrams of a hydrogen gas filling system of the present invention.
  • FIG. 4 is a cross-sectional view and a front view of the soft capsule (soft coated film storage container) of the present invention.
  • 5 and 6 are process explanatory diagrams for explaining the hydrogen injection and sealing method of the present invention.
  • FIG. 7 is a structural view of a solid-state adhesive rod and a grouting nozzle for sealing after gas injection in a storage container of the present invention.
  • FIG. 8 is a plan view and a side view showing a water jacket constituting the hydrogen generating candy storage container of the present invention.
  • FIG. 1 illustrates an embodiment of the present invention.
  • the hydrogen filling the hydrogen storage container for allowing hydrogen to be absorbed by the human body has a purity of 99.999% or more in quality capable of being absorbed or metabolized in the human body and the impurity of the hydrogen gas is lower than the concentration shown in Table 1 below .
  • the contained dust be no more than one per cubic foot (ft 3 ) of particles less than 0.1 micrometer (um).
  • Hydrogen gas is a combustible material that has a flash point of 550 ° C and is a colorless, odorless, tasteless, nontoxic, suffocating gas that explodes within the limits of 4% to 74% of the volume limit in air and a volume ratio of 18% to 59% Hydrogen atoms are the smallest and lightest in diameter among the elements and can easily be separated from water molecules and rapidly diffuse in the air to disappear into the air and pass through the human skin cells .
  • Hydrocracking enzymes in soil microorganisms have been shown to play an important role in anaerobic metabolism as an enzyme that catalyzes the reversible oxidation of hydrogen molecules, And decomposes hydrogen molecules into hydrogen ions and electrons.
  • a mechanism for using iron as a catalyst has recently been discovered.
  • Enzymes involved in this electron transport are known to be essential for anaerobic metabolism to maintain a low oxidation-reduction potential (ORP).
  • the hydrogen gas in the hydrogen storage container such as drinking water or dissolved in drinking water, is a hydrogen molecule that is decomposed by the hydrogenase (hydrogenase) present in the microorganisms present in the body during metabolism in the body, It is known to be separated into.
  • the separated hydrogen ions act as active hydrogen, which is a hydrogen atom, and serves to erase active oxygen.
  • the hydrogen storage container of the present invention set the ratio of active hydrogen to active hydrogen much higher than that of hydrogen rich part. Thereby supplying hydrogen gas.
  • a container of candy in the form of a capsule is the first choice for this purpose.
  • the airtightness of the candy is excellent in the airtightness of the conventional soft candy, the amorphous hard candy and the unsweetened hard candy, and the airtightness to the hydrogen gas is good and the calorie is 10Kcal Or less, the tensile strength is high, the thermal deformation is good during the process of producing the container for storing hydrogen, the glass transition temperature is in the range of 3% or more to 38 ° C or more, It is desirable to make similar mixtures.
  • Examples of conventional candy materials that can be applied to the mixture include sugars such as sugars, maltose and sweet potato and mixtures of carbohydrate syrup mixtures such as starch, maltitol, mannitol, sorbitol, isomalt and xylitol and polyols, Gelatin, glycerin or the like, which is used as a raw material of the capsule, may be used as an additive.
  • sugars such as sugars, maltose and sweet potato
  • mixtures of carbohydrate syrup mixtures such as starch, maltitol, mannitol, sorbitol, isomalt and xylitol and polyols, Gelatin, glycerin or the like, which is used as a raw material of the capsule, may be used as an additive.
  • a cylindrical thin space is opened with one side opened inside the candy
  • the space is first evacuated, then the hydrogen gas below the atmospheric pressure is filled, and the open space is sealed and sealed to become the hydrogen storage container of the hydrogen gas.
  • the composition and structure of candy are similar to glass, the outside air can not penetrate into the inside, but some of the hydrogen molecules inside can leak out of the candy, but the principle is that leakage does not occur under the internal pressure below atmospheric pressure.
  • the gas storage container In order to store the hydrogen gas safely, the gas storage container is accommodated in a regular hard capsule having high airtightness so that the airtightness is improved secondarily, and the upper and lower portions are put in a pocket type packaging structure made of an aluminum layer, In addition, the hydrogen storage container is manufactured.
  • Hard candy is also commonly referred to as hard sweets or hard boiled candies. These are basically amorphous and hard sugars which are obtained by strongly dehydrating carbohydrate syrups. Essentially amorphous hard candies containing so-called sugar-free or polyols can also be obtained using hydrogenated carbohydrate syrups or slightly digested carbohydrate syrups. Sugar-free hard candy is becoming increasingly popular because it inhibits the formation of tooth corrosion while exhibiting similar sensory properties, and less calories than conventional sugar hard candy. Generally, sugar-free hard candies are prepared by boiling a mixture of water-soluble polyols.
  • the mixtures of these polyols are boiled under atmospheric pressure to 150 < 0 > C to 200 < 0 > C to evaporate most of the water.
  • a boiling process is usually carried out in a vacuum, where the normal moisture content is lowered to 2.5% or less, or to a lower value of 1.5% or less.
  • various substances such as antioxidants, pigments, strong sweeteners, acids, plant extracts, vitamins and active inhibitors, it is cooled again and placed in a mold, To make a shape. This technique for hard candy is well described in Korean Patent Registration No. 0163252.
  • the gas storage container of the present invention is a gas cell made of candy in the form of a capsule to store hydrogen gas.
  • the gas storage container (2) is made of a hard capsule (16) having a clearance space therein.
  • the gas storage container 2 is placed inside and the upper part 4 of the hard capsule and the lower part 3 of the hard capsule are adhered under a nitrogen gas atmosphere.
  • the hydrogen storage container 1 in which the bonding portion 5 is formed is made in the hard capsule.
  • the gas storage container 2 includes a container cylinder 6, a cylinder outer 8 of the container, a cylindrical inner 9 of the candy, And hydrogen gas 7 of atmospheric pressure or less is stored in the inside of the cylinder 9.
  • the hydrogen gas 7 is produced in such a size that it can be orally put into the cylinder.
  • the outer diameter D and the outer diameter D of the outer cylinder are 8 mm and the length L2 of the outer cylinder is 14 mm, And the end plates 10 at both ends, does not exceed 22 mm.
  • the change in the pressure of the hydrogen gas stored in the hydrogen storage vessel (1) according to the external temperature change is an ideal gas, as shown in the following Table 2, assuming an ideal gas, hydrogen gas the space of the container and the capsule between the response to the gas storage vessel (2) and a rigid capsule (16) to the temperature change as a 0.87 kg / cm 2 at minus 30 °C and indicating at 30 °C 1.09 kg / cm 2
  • the space is spaced by 1% or more of the outer diameter 14 of the container cylinder and when the pressure of the inside of the container 9 is higher than the pressure of the outside of the container 8, When a part of the gas 7 permeates to the outside 8 of the cylinder, the inside of the space 17 of the vessel and the capsule is trapped with nitrogen.
  • the gas storage container 2 is made of a conventional candy, amorphous hard candy, hard sugar candy, sugar-free hard candy, and the like, according to the conventional candy manufacturing method, the airtightness to the air or the nitrogen gas is complete and the airtightness to the hydrogen gas is good,
  • the glass transition temperature is in the range of 3% or more to 38 ° C or more at the glass transition temperature, and the glass transition temperature It is desirable to make a mixture similar in structure and structure.
  • Conventional candy materials that can be applied to the mixture include sugars such as sugars, maltose and sweet potato and mixtures of carbohydrate syrup mixtures such as starch, maltitol, mannitol, sorbitol, isomalt and xylitol and polyols, And gelatin or glycerin used as a raw material of the capsule may be used as an additive.
  • the purity of the hydrogen gas filled in the gas storage container (2) is 99.999% or more, and the amount of dust contained in the hydrogen gas is 1 or less per 1 ft 3 of the inlet of 0.1 ⁇ m or less.
  • the hydrogen gas 7 charged below the atmospheric pressure is shut off from the outside of the gas storage container 2 while the hydrogen gas in the gas storage container 2 is atmospheric pressure or higher, The leakage of hydrogen gas does not occur when the pressure of the hydrogen gas in the gas container is equal to or lower than the atmospheric pressure.
  • the necessary additives are put in each of the predetermined moisture-free massecaps made of a mixture of saccharides, carbohydrate syrups and polyols as raw materials, To make a shape.
  • the additives the iron (Ferrous fumarate) promoter for decomposing hydrogen molecules into hydrogen atoms (active hydrogen), vitamin C, vitamin E to assist the antioxidant role, polyphenols (Polyphenol), carotene (Carotene), calcium, etc. . It is preferred that iron does not exceed 4 mg per capsule.
  • the flask of the container is the same as the method of molding the conventional candy, and the flask has a shape and structure such that the temporary container 21 of FIG. 2 a can be molded, And the upper protruding portion 24 of the container can be pressed by the compression band 26.
  • the lower portion of the hydrogen filling nozzle 25 made of metal is inserted in the middle of the temporary container 21, .
  • the length of the temporary container 21 is equal to the total length L1 of the container plus the height of the container upper closure portion 28 and the width of the circular thermocompression band 26 is equal to the thickness of the end plate 10 of the container.
  • the upper protruding portion 24 of the temporary container 21 is filled with a circular thermocompression band 26 and the inside of the hydrogen filling nozzle 25 is pumped to a degree of vacuum of about 10 -1 Torr by a vacuum pump
  • the hydrogen gas is supplied from the hydrogen gas supply unit to the atmospheric pressure or less.
  • the hydrogen filling nozzle 25 is heated by the built-in heater to a temperature higher than the glass transition temperature, and the length of the inside of the cylinder ) And the width of the circular thermocompression band 26 to the end of the container.
  • the cylindrical length of the temporary container 21 is the length of the inside of the cylinder of the container ( And the width of the circular thermocompression bonding band 26.
  • the height of the upper protruding portion 24 of the container is raised to a temperature (glass transition temperature) or higher by the heater provided in the circular thermocompression band 26,
  • the thermocompression band 26 is tightened by a length corresponding to the width of the circular thermocompression band 26 to be the same as the lower circumferential direction of the temporary container 21 until it is sealed.
  • the interior of the container 9 of the container is made in the interior of the temporary container 21, leaving only the upper end 28 of the container.
  • temperature and moisture are controlled to be balanced in the temporary container 21 by the control device.
  • FIG. 3 is a schematic view of a hydrogen gas filling system of the present invention. Referring to FIG. 3A, when a hydrogen filled net pipe connected to a hydrogen filling nozzle unit is used for both pumping and filling,
  • the hydrogen gas filling system includes a hydrogen filling nozzle unit 31 composed of n hydrogen filling nozzles 25 and auxiliary devices, a hydrogen filled net pipe connected to the hydrogen filling nozzle unit 31, A vacuum pumping unit including a vacuum pump 41 connected to the pipe 32 and a pumping gas control valve 42 and a hydrogen pumping unit connected to the hydrogen filled net pipe 32 and connected to the hydrogen gas supply source 33, , A hydrogen gas supply unit including a hydrogen gas control valve 35 and a hydrogen gas filter 36 and a hydrogen gas supply unit connected in parallel with the hydrogen gas supply unit to the hydrogen filled net pipe 32, A nitrogen gas supply unit including a pressure regulator 38, a nitrogen gas control valve 39 and a nitrogen gas filter 40; a pumping gas exhaust valve 44 for exhausting the pumping gas; And a valve (43).
  • FIG. 3 (b) shows a case where the hydrogen-filled mesh pipe connected to the hydrogen-filled nozzle unit and the pumping gas mesh pipe are used separately, and the hydrogen-filled nozzle unit 31 composed of the n hydrogen filling nozzles 25 and the auxiliary devices the hydrogen filled nozzle unit 31 and the hydrogen filled meshed pipe 32 are separated by the n pumping gas isolation valves 45 and connected to the pumping gas meshed pipe 46 connected to the hydrogen filled nozzle unit 31
  • a vacuum pumping unit having a vacuum pump 41 and a pumping gas control valve 42 and a hydrogen pumping gas separating valve 45 connected to the hydrogen filling nozzle unit 31 and the hydrogen-
  • the nitrogen gas supply unit connected to the hydrogen-filled meshed pipe 32, the nitrogen gas supply unit connected to the hydrogen-filled meshed pipe 32 in parallel with the hydrogen gas supply unit, and the pumping gas exhaust valve 44, a feed gas exhaust valve 43 for purging the feed gas, and a pumping gas Which is a hydrogen gas filling system.
  • a hydrogen gas control valve 35 a nitrogen gas control valve 39, a feed gas exhaust valve 43 and a pumping gas control valve 43
  • the pumping gas exhaust valve 44 is closed and the vacuum pump 41 is operated while the pumping gas exhaust valve 44 is opened.
  • the pumping gas control valve 42 is opened, The inside of the n hydrogen filling nozzles 25 of the filling net pipe 32 and the hydrogen filling nozzle unit 31 is pumped to increase the degree of vacuum to 10 -1 Torr.
  • the pumping gas control valve 42 When the n hydrogen filling nozzles 25 and its passage reach a predetermined degree of vacuum, the pumping gas control valve 42 is closed and the hydrogen gas control valve 35 of the hydrogen gas supply unit is opened to open the n hydrogen filling nozzles 25, The hydrogen gas is supplied from the hydrogen gas supply source 33 through the hydrogen gas pressure regulator 34 and the filter 36 until the hydrogen gas reaches the atmospheric pressure.
  • the hydrogen gas control valve 35 When the predetermined hydrogen gas filling is completed, the hydrogen gas control valve 35 is closed to stop the supply of the hydrogen gas and the supply of the hydrogen gas is stopped by the respective circular thermocompression bands 26 in accordance with the thermocompression procedure as described above 24) to seal the filled hydrogen gas.
  • the nitrogen gas in the nitrogen gas supply unit is used for purifying the interior of the charging system during maintenance or emergency.
  • the nitrogen gas control valve 39 is opened to supply the nitrogen gas pressure regulator 38 and the filter (40).
  • the nitrogen gas can also be used for nitrogen sealing inside the system when the equipment is shut down.
  • the supply gas exhaust valve 43 may open the valve as needed to exhaust the hydrogen gas or exhaust the nitrogen gas.
  • the n pumping gas isolation valves 45 are closed to separate the pumping gas control valve 42 from the hydrogen-filled meshed pipe 32
  • the pumping gas exhaust valve 44 is opened and the vacuum pump 41 is put into operation and the pumping gas exhaust valve 44 is closed and then the pumping gas control valve 42 is opened to open the pumping gas meshing pipe 46, And the hydrogen filling nozzles 25 of the hydrogen filling nozzle unit 31 to increase the degree of vacuum to 10 -1 Torr.
  • the pumping gas control valve 42 When the inside of the n hydrogen filling nozzles 25 and its passage reach a predetermined degree of vacuum, the pumping gas control valve 42 is closed and the n pumping gas isolation valves 45 are closed to pass through the hydrogen filled meshed pipe 32
  • the hydrogen gas control valve 35 of the hydrogen gas supply unit is opened and the hydrogen gas pressure regulator 34 and the filter 36 are supplied from the hydrogen gas supply source 33 until the n hydrogen filling nozzles 25 reach atmospheric pressure. And then the hydrogen gas is charged.
  • the hydrogen gas control valve 35 When the predetermined hydrogen gas filling is completed, the hydrogen gas control valve 35 is closed to stop the supply of the hydrogen gas, and by the respective circular thermocompression bands 26, The lower portion is compressed to seal the filled hydrogen gas.
  • the function of the nitrogen gas supply portion is as described above.
  • Massecuites from which the water was removed from the raw material of the candy were prepared, the necessary additives were added, and after cooling, the flask of the candy was prepared, and the hydrogen filling nozzle was set at the center portion in the correct position, Mold the temporary container by inserting the massager with the filling nozzle inserted.
  • thermocompression band is filled in the upper protruding portion of the temporary container, the inside of the hydrogen filling nozzle is vacuum pumped, hydrogen gas is filled in the hydrogen filling nozzle, and the temperature of the hydrogen gas filling nozzle is raised to the end of the upper protrusion. Is formed.
  • the upper protruding portion is compressed by the circular thermocompression band until it is sealed, and the upper portion becomes a sealed container when tightened.
  • the production of the hydrogen storage container of the present invention is completed.
  • the completed hydrogen storage container is packed in a pocket-type pharmaceutical structure with an aluminum layer on the top and bottom.
  • Described is a method for manufacturing a gas storage container that is soft and not hard by further improving the container for gas storage.
  • the material used for the production of the temporary gas storage container of the soft film is ordinary gelatin extracted from natural collagen, succinic acid gelatin in which the amino group is substituted with a carboxyl group to enhance stability of disintegration,
  • One or more compounds selected from the group consisting of sorbitol sorbitol or sorbitol series such as glycerin, concentrated glycerin, starch, plasticizer or softening agent, polyglycitol syrup, sucrose, mannitol, xylitol, maltose, reduced maltose syrup, maltitol, polyethylene glycol,
  • sorbitol sorbitol or sorbitol series such as glycerin, concentrated glycerin, starch, plasticizer or softening agent, polyglycitol syrup, sucrose, mannitol, xylitol, maltose, reduced maltose syrup, maltitol, polyethylene glycol
  • the base oil is one or more selected from soybean oil, safflower oil, refined fish oil, refined oil, sesame oil, red pepper seed oil, wheat germ oil, grape seed oil, olive oil, seed oil, evening primrose oil,
  • a temporary soft container is prepared by inserting contents into the center of two film bases and bonding the two films in an elliptical shape to encapsulate the contents.
  • a film having a uniform film thickness is formed and cooled by a cold air having a relative humidity of about 12 to 20 ° C and a relative humidity of about 20 to 30%, gelled, and then transferred to a molding machine.
  • the contents are charged through the charger by a predetermined amount.
  • the flexible film gas storage container has an outer shape such as a rugby ball in which a longitudinal section view becomes an elliptical shape and a transverse sectional view becomes a circular shape.
  • the gas storage container is a soft coated gas storage container 51 containing a soft coating film in the form of a capsule and containing a hydrogen gas 7 at a predetermined pressure as a base of the content and storing a small amount of the remaining amount 58.
  • This may be a structure that can be accommodated with a predetermined space inside the hard capsule to be protected by the hard capsule on the outside thereof.
  • the flexible film gas storage container 51 is formed with the outer portion 52 of the container, the inner portion 53 of the container, the joint portion 54 of the container, and the nozzle insertion port 57,
  • the inside of the vessel 53 has a structure in which hydrogen gas 7 not exceeding twice the atmospheric pressure and 3 to 30% of the remaining amount of the fuel 58 are stored.
  • the outer diameter of the vessel (56: D) was manufactured to a standard size for oral ingestion. .
  • the dissolution time of the soft-coated gas container should be within 12 minutes if it is reinforced with a hard capsule, and within 30 minutes if it is to be taken by soft capsule alone.
  • the standard is to take into account the pressure applied inside and outside the container
  • the thickness of the flexible film temporary container 61 during molding is set to 0.8 to 1.1 mm in order to allow the tension or the elasticity to withstand 1.1 times the predetermined pressure, To be 0.7 to 1.0 mm.
  • the thickness of the joint portion 54 of the container is 0.6 to 0.95 mm as a standard after cooling and drying, and the thickness of the restored nozzle insertion port 57 is 0.7 to 1.0 mm on the basis of the cooling dryness.
  • the manufacturing method of the soft film gas storage container comprises a molding process of the soft film storage container and filling and sealing of the hydrogen gas.
  • the method first comprises filling the microcrystalline soft-film temporary container 61 with hydrogen gas and sealing the same to produce the soft-film-containing gas storage container 51, A predetermined thickness is imparted to the components of the used soft film to reinforce the tensile force and the elasticity so as to make the flexible film temporary container 61 having the joint portion 54 of the sealed container filled with the retained contents 62 .
  • the hydrogen filling nozzle insertion port 63 is defined in the joint portion 54 of the container in the lower end plate portion of the container in a state where the temporary container 61 is vertically positioned, Shaped hydrogen-filled nozzle 64 is inserted into the temporary vessel 61 from the lower side to the upper side with a length corresponding to the central portion of the holding depth.
  • the hydrogen-filled nozzle 64 is moved to a length corresponding to the depth of the remaining amount of the interior of the hydrogen-
  • the holding contents 62 are pumped out through a hydrogen filling nozzle and discharged.
  • the remaining amount of the residues 58 in the remaining temporary container becomes 3 to 30% so as to be laid on the bottom of the container.
  • the gas 7 is charged to a predetermined pressure. At this time, the filling pressure shall not exceed twice the atmospheric pressure.
  • the hydrogen-filled nozzle 64 is completely retracted through the filling nozzle inserting port 63 of the temporary container 61 and the airtightness maintaining film formed by itself by the remaining fuel amount 58 So that the nozzle inserting opening 65 damaged by the elasticity of the coating itself is provisionally kept airtight.
  • the material of the soft coating is injected into the damaged nozzle inserting opening 65 by the grouting nozzle 66 while the temporary container 61 is temporarily kept air-tight, It is grouting by electric temperature (200 o C or less) to make it to be bonded.
  • the grouting nozzle 66 used in the grouting process is a molten adhesive for injecting the molten adhesive of the solid phase into the damaged nozzle inserting port 65 in contact with the damaged nozzle inserting port 65,
  • a solid-state bonding rod heating part 72 having an injection part 71 of a rod, an electric heater and a heat conductor capable of heating up to 200 o C, and a solid-phase bonding rod heating part 72 which pushes the solid-state bonding rod through a cylindrical passage and a passage And a solid-state adhesive tape 74 inserted into the solid-state adhesive-stick supporting portion.
  • the material of the soft coating for grouting is a solid-state adhesive rod having gelatin as a main component and having high adhesive property among the soft coating materials of the main body, so that even at 200 o C or less, the melted material can penetrate to the damaged part.
  • a soft coated gas storage container 51 sealed with a hydrogen gas and a residual amount of the inside is prepared and is ready to be accommodated inside the protective hard capsule.
  • the hydrogen gas filling system shown in FIG. 3B is used as the hydrogen filling system.
  • the temporary filling container for filling the hydrogen gas and the temporary container sealed inside the filling container are loaded in the hydrogen filling nozzle part and the n filling holding and separating valves 45 are closed so that the hydrogen filling nozzle part is separated from the hydrogen filling filling pipe 32
  • the maintenance and discharge control valve 42 is closed, the maintenance discharge valve 44 is opened, the maintenance pump 41 is operated to discharge the maintenance of the maintenance pump inlet line, and then the maintenance pump is maintained
  • the discharge valve 44 is closed and the pumping maintenance control valve 42 is opened to connect the n hydrogen filling nozzles 64 of the pumped retention pipe 46 and the hydrogen filled nozzle unit 31 and the soft coated gas storage vessel 51, And pumped out the oil in the sump.
  • the pumping maintenance control valve 42 is closed and the n pumping maintenance release valves 45 are opened to allow the hydrogen filling nozzle section to communicate with the hydrogen filled net pipe (32).
  • the hydrogen gas control valve 35 of the hydrogen gas supply unit is opened to supply the hydrogen gas pressure regulator 34 and the filter 34 from the hydrogen gas supply source 33 until the n hydrogen-filled nozzles 25 reach a predetermined pressure.
  • the hydrogen gas control valve 35 is closed to stop the supply of the hydrogen gas, the hydrogen gas filling nozzle is retracted and taken out of the temporary container, and instead the grouting nozzle 66 is inserted into the nozzle insertion opening And the material of the soft coating film is grouted by being injected into the damaged nozzle insertion port 65 at a predetermined injection pressure and temperature (200 o C or less). In this way, the soft coated gas storage container 51 sealed with the hydrogen gas and the remaining amount of the inside is manufactured and ready to be accommodated inside the protective hard capsule.
  • the present invention relates to a hydrogen-producing candy obtained by mixing a substance producing hydrogen gas in the large intestine by intestinal bacterial group with candy such that it is 30% to 70% with respect to candy.
  • Flatulence is a mixed gas of byproducts in the digestive process of mammals, which is transported and released into the rectum by the peristallic action of the same digestive organs that causes the excreta to come down from the large intestine.
  • the ingredients are generally known as shown in Table 3 below.
  • Table 3 Item nitrogen Oxygen Hydrogen carbon dioxide methane main ingredient 20 to 90% 0 to 10% 0 to 30% 10 to 30% 0 to 10% Average 55% 5% 15% 20% 5% Generation circle When inhaled When inhaled Fermentation in large intestine Fermentation in large intestine Fermentation in the colon (30% of adults only)
  • malodorous farts are composed of meat proteins such as sucrose, indole and ammonia, and compounds containing methane sulfur such as methaneethiol, hydrogen sulfide, and diemthylsulfide. It corresponds to about 1% of the gas produced.
  • Humans emit 500 to 700 cm 3 of gas per day on an adult basis, about 15 times per day.
  • the hydrogen gas produced is 75 to 105 cm 3 per day.
  • the other part is higher than the partial pressure of the blood through a lumen, which is a passage through which nutrients in the intestines pass, into the bloodstream of the barrier by the process of diffusion.
  • Hydrogen gas transported along the blood stream may penetrate into the cell, some of which may come out of the blood and exhale when it passes through the lungs. At this time, most of the carbon dioxide and methane gas that are produced together are released through the anus, and some go into the bloodstream of the barrier and combine with other carbon dioxide in the varicose veins.
  • Test results of respiratory hydrogen are influenced by factors related to quantitative or qualitative aspects of intestinal bacterial populations.
  • the aim of the study was to see if the ability of the hydrogen gas to evolve after oral administration of lactolose in the presence of loss in the origin of the colon. -
  • the results of the test showed that in patients with fully intestinal obstruction, patients who had a well-controlled or partially resected colon carcinoma, hydrogen gas Of the total emissions.
  • Curcumin has been shown to protect against carcinogenesis of the skin, oral cavity, small intestine, and colon, and to inhibit the angiogenesis and metastasis of new blood vessels from existing blood vessels in many animal models of cancer.
  • - Cancer chemopreventive Curcumin inhibits the spread of cancer cells by capturing them at various stages of the cell cycle and inducing the death of the programmed cells.
  • curcumin inhibits the biologic activation of carcinogens by inhibiting cytochrome P450 isozyme, which detoxifies the drug by electron transfer chain, which is also deduced to be associated with curcumin intestinal hydrogen gas.
  • Materials promoting the production of odorless gas include;
  • lactose, fructose, and artificially synthesized lactulose which are contained in dairy products including milk, and which correspond to small sugars of carbohydrates.
  • the reason for this is the lack of enzymes, lactase, which can not be broken down in the small intestine.
  • the raffinose system which is contained in soybean plants, cabbage, broccoli, and asparagus, and which is a small saccharide of carbohydrates, contains three saccharides, raffinose, four sugars, stachyose, 5 Saccharides are typical examples of verbascose.
  • A-galactosidase a-GAL
  • an enzyme that hydrolyzes these substances is not digested and absorbed in the small intestine because it is not present in human digestive organs .
  • turmeric curcumin used as food spices
  • capsaicin belonging to the acid amides of pepper inulin which is a polysaccharide contained in porcine potatoes and burdock
  • gingerrol of ginger a polysaccharide contained in porcine potatoes and burdock
  • Allicin a sulfur compound contained in garlic
  • the gluten in the endosperm of wheat, rye, barley and oats is composed of proteins called gliadin and glutenin, and glutenin is involved in the mutual binding of the network.
  • the enzyme that hydrolyzes the ash is deficient in humans, so it can not be decomposed and absorbed in the small intestine.
  • Example 2 a method of adding a compound inducing the production of beneficial hydrogen gas in the candy container or candy in the step of the predetermined moisture-free messit made using the mixture as a raw material in Example 2 a) (Lactose) extracted from dairy products containing milk and lactulose synthesized artificially with fructose and galactose, or by adding one or more compounds such as soybean plants, cruciferous vegetables such as cabbage, broccoli Raffinose, which is a three-saccharide of the raffinose system (RFO) extracted from asparagus, kale, radish, and Chinese cabbage, and one or two of staphylose and five saccharides, such as staphylose and verbascose, Adding more compounds, curcumin extracted from turmeric used as edible spices, capsaicin of pepper, One or more compounds may be added to the endosperm such as wheat, rye, barley, oats, and the like from inulin, gingerrol, allicin extracted from
  • the step of adding a compound which induces the production of beneficial hydrogen gas in the candy container or candy in the intestine is carried out by adding lactose, lactolose, raffinose, stachyose,
  • One or more compounds are added to the methacetate for molding or injection by adding one or more compounds from chose, curcumin, capsaicin, inuline, gingerol, alicin, asparagine, glutenin and the like to produce intestinal hydrogen-producing candy.
  • BHT breath hydrogen test
  • the container 4 In order to dissolve the gas storage container 2 together with the drinking water into the oral cavity and dissolve in the intestine within a predetermined period of time, the container 4 is placed in the lower portion 3 of the conventional hard capsule under a nitrogen gas atmosphere, The bonding portion 5 of the hard capsule which is the portion where the lower portion 3 and the upper portion 4 of the next hard capsule overlap each other is adhered to complete the production of the hydrogen storage container 1.
  • the hard capsule 16 is manufactured by a conventional manufacturing method, but the area of the adhesive portion where the upper and lower portions of the capsule are overlapped to increase the airtightness, moisture resistance and tensile strength, rather than the ordinary hard capsule for medicines containing the powder or granule, 1, and the position of the adhesive portion is the central portion of the hard capsule 16 in order to protect it from external impact as shown in Fig.
  • the hard capsules may be made of water-soluble cellulose derivatives, gelling agents, gelatin, polyethyleneglycol (PEG), glycerin or the like, or may be added with a nano silver coating. It is selected to be soluble in warmed purified water and dissolve within 15 minutes.
  • PEG polyethyleneglycol
  • the aluminum pack is a small-sized, compression-sealed aluminum pack which is heat-treated.
  • FIG. 8 is a view illustrating an example of a fire water jacket according to an embodiment of the present invention.
  • FIG. 8 is a plan view of a water jacket
  • FIG. 8 is a side view of a water jacket.
  • one or more compounds such as polypropylene, low-density polyethylene, and high-density polyethylene which can be melted in an environment of 120 ° C or higher as shown in FIG. 8
  • a cushion-shaped unit water jacket (1) as a basic unit.
  • Water or refractory antifreeze can be contained inside, and the convex part (2) and the concave part (3) of the water jacket are alternately arranged so as to be foldable according to the standard.
  • female hooks 4 made of plastic or metal and male hooks 5 at the other end are arranged so as to be connected to each other.
  • It is a cylindrical capsule type container made of a material which is dissolved in the gas when it is stored in contact with water, and then it is filled with carbon monoxide, nitrogen monoxide, xenon, helium etc. in addition to hydrogen. It can have a medical effect.
  • Hydrogen is the most widely used antioxidant that protects tissues by preventing and curing oxidative damage to cells in mammals, including humans, ( * OH) and peroxynitrite (ONOO - ) corresponding to strong active oxygen generated in various parts of the human body.
  • Carbon monoxide is a toxic gas that induces hypoxia in the cell tissue by decreasing the oxygen transport capacity of blood at a high concentration. However, it acts as an antioxidant at low concentration (ppm unit), and it causes hypoxia such as ischemia reperfusion injury (ischemia) (O 2 - ) produced in the mitochondria that synthesize energy in the body can be removed, and the effect of the combined treatment with the hydrogen gas is enhanced .
  • hypoxia such as ischemia reperfusion injury (ischemia) (O 2 - ) produced in the mitochondria that synthesize energy in the body can be removed, and the effect of the combined treatment with the hydrogen gas is enhanced .
  • Nitric oxide is a signaling molecule in the body at low concentrations, which increases blood supply to blood vessels and protects tissues from oxidative damage of cells. At high concentrations, however, peroxynitrite (Peroxynitrite), it is reported that attention should be paid to maintaining the balance.
  • Xenon and Helium are inert rare gases that have been shown to help protect myocardial ischemia reperfusion injury by helping to activate the signal at low concentrations in the body and protecting it from cell oxidation.
  • These molecular gases can be supplied to the human body by sealing them in gas storage containers.
  • the gas storage container, the filling method, and the container manufacturing method can be applied to the above-described techniques to seal the hydrogen gas.

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Abstract

La présente invention porte sur une technique permettant d'administrer des gaz dans l'organisme humain ou de produire des gaz à l'intérieur du corps humain, notamment sur un procédé pouvant encapsuler des gaz, ainsi que sur un récipient pour le stockage des gaz. La présente invention porte sur une capsule de stockage des gaz et sur un procédé de production de la capsule de stockage des gaz, la capsule étant dissoute dans de l'eau de telle sorte que son étanchéité à l'air soit progressivement dégradée, et que le gaz contenu dans la capsule puisse progressivement s'échapper vers l'extérieur de la capsule. La présente invention porte aussi sur un matériau générateur d'hydrogène qui va produire directement des gaz hydrogénés in vivo, ainsi que sur un bonbon générateur d'hydrogène pour encapsuler directement l'hydrogène par utilisation du matériau, et administration de l'hydrogène ainsi encapsulé dans les intestins, ainsi que sur un procédé de production du bonbon.
PCT/KR2011/002536 2010-04-15 2011-04-11 Récipient pour le stockage de gaz, procédé de charge d'hydrogène, et appareil de charge d'hydrogène WO2011129567A2 (fr)

Applications Claiming Priority (4)

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KR10-2010-0034945 2010-04-15
KR20100034945A KR101237957B1 (ko) 2010-04-15 2010-04-15 연질피막 수소보관용기 및 그 제조 방법
KR20100127087A KR101311697B1 (ko) 2010-12-13 2010-12-13 수소생성사탕용기
KR10-2010-0127087 2010-12-13

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US7396381B2 (en) * 2004-07-08 2008-07-08 Air Products And Chemicals, Inc. Storage and delivery systems for gases held in liquid medium
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