WO2011120506A8 - Implantat mit einer sandwich-struktur, implantatsystem und aufnahmeträger - Google Patents

Implantat mit einer sandwich-struktur, implantatsystem und aufnahmeträger Download PDF

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Publication number
WO2011120506A8
WO2011120506A8 PCT/DE2011/000342 DE2011000342W WO2011120506A8 WO 2011120506 A8 WO2011120506 A8 WO 2011120506A8 DE 2011000342 W DE2011000342 W DE 2011000342W WO 2011120506 A8 WO2011120506 A8 WO 2011120506A8
Authority
WO
WIPO (PCT)
Prior art keywords
implant
sandwich structure
annulus
woven
intervertebral disc
Prior art date
Application number
PCT/DE2011/000342
Other languages
English (en)
French (fr)
Other versions
WO2011120506A3 (de
WO2011120506A2 (de
Inventor
Uwe Merklein
Thomas Gries
Thorsten Deichmann
Annahit Arshi
Original Assignee
3T Textiltechnologietransfer Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3T Textiltechnologietransfer Gmbh filed Critical 3T Textiltechnologietransfer Gmbh
Priority to JP2013501629A priority Critical patent/JP2013523225A/ja
Priority to US13/638,134 priority patent/US20130110245A1/en
Priority to EP11721991A priority patent/EP2552502A2/de
Publication of WO2011120506A2 publication Critical patent/WO2011120506A2/de
Publication of WO2011120506A8 publication Critical patent/WO2011120506A8/de
Publication of WO2011120506A3 publication Critical patent/WO2011120506A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A61L27/3856—Intervertebral discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

In der Therapie schmerzhafter Bandscheibenerkrankungen wird versucht, einer Degeneration entgegen zu wirken. Zum einen werden künstliche Nucleus Pulposus-Prothesen entwickelt und zum anderen regenerative Therapieverfahren mit dem Einsatz von Biomaterialen in der Bandscheibe verfolgt. In beiden Fällen kann es zu massiven Herniationen der genannten Materialien durch bestehende oder zugangsbedingt vergrößerte Anulus-Defekte kommen. Aus dieser Sicht ist der sichere Verschluss und die Regeneration des Anulus Fibrosus eine wichtige Voraussetzung und Weiterentwicklung zur Therapie von Bandscheibenvorfällen und degenerativen Bandscheibenvorfällen. Hierzu schlägt die Erfindung als Verbesserung vor, ein Implantat zu verwenden, welches eine Sandwich-Struktur umfasst, wobei zwischen einem zweilagigen Vlies eine Verstärkungsstruktur angeordnet ist und das Vlies insbesondere ein biokompatibles Material umfasst.
PCT/DE2011/000342 2010-03-30 2011-03-29 Implantat mit einer sandwich-struktur, implantatsystem und aufnahmeträger WO2011120506A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2013501629A JP2013523225A (ja) 2010-03-30 2011-03-29 サンドイッチ構造、インプラントシステム及び支持担体を備えるインプラント
US13/638,134 US20130110245A1 (en) 2010-03-30 2011-03-29 Implant having a sandwich structure, implant system and implant support
EP11721991A EP2552502A2 (de) 2010-03-30 2011-03-29 Implantat mit einer sandwich-struktur, implantatsystem und aufnahmeträger

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102010013485.6 2010-03-30
DE102010013485 2010-03-30
DE102010048710.4 2010-10-19
DE102010048710A DE102010048710B4 (de) 2010-03-30 2010-10-19 Implantat mit einer Sandwich-Struktur

Publications (3)

Publication Number Publication Date
WO2011120506A2 WO2011120506A2 (de) 2011-10-06
WO2011120506A8 true WO2011120506A8 (de) 2011-12-15
WO2011120506A3 WO2011120506A3 (de) 2012-02-23

Family

ID=44116184

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2011/000342 WO2011120506A2 (de) 2010-03-30 2011-03-29 Implantat mit einer sandwich-struktur, implantatsystem und aufnahmeträger

Country Status (5)

Country Link
US (1) US20130110245A1 (de)
EP (1) EP2552502A2 (de)
JP (1) JP2013523225A (de)
DE (1) DE102010048710B4 (de)
WO (1) WO2011120506A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10588732B2 (en) 2014-03-07 2020-03-17 IconLab USA, Inc. Multipurpose implant with modeled surface structure for soft tissue reconstruction
RU2699811C1 (ru) 2014-03-07 2019-09-11 Айконлаб Инк. Многоцелевой имплантат с заданной структурой поверхности для реконструкции мягких тканей
US10765780B2 (en) * 2014-12-05 2020-09-08 Gunze, Limited Method of producing tissue regeneration substrate
CN108714248A (zh) * 2017-06-16 2018-10-30 无锡市锡山人民医院 一种三明治式复合膜支架的制作方法
CN110882093A (zh) * 2019-12-18 2020-03-17 上海畅迪医疗科技有限公司 一种人工椎间盘
WO2023249065A1 (ja) * 2022-06-22 2023-12-28 学校法人藤田学園 組織再生促進シート
JP7502751B2 (ja) 2022-06-22 2024-06-19 金井重要工業株式会社 組織再生促進シート

Family Cites Families (21)

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CA992255A (en) * 1971-01-25 1976-07-06 Cutter Laboratories Prosthesis for spinal repair
US5192326A (en) * 1990-12-21 1993-03-09 Pfizer Hospital Products Group, Inc. Hydrogel bead intervertebral disc nucleus
GB2268064B (en) * 1992-05-29 1996-05-22 Roozbeh Shirandami Discontinuous fibre composite implant prosthesis
CA2114282A1 (en) * 1993-01-28 1994-07-29 Lothar Schilder Multi-layered implant
GB9704749D0 (en) * 1997-03-07 1997-04-23 Univ London Tissue Implant
JP2003505205A (ja) * 1999-07-28 2003-02-12 リジェネレーション テクノロジーズ インク． 核酸送達ビヒクルとしての軟骨マトリクス又は骨マトリクス
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DE19942611C1 (de) * 1999-08-31 2001-07-05 Ethicon Gmbh Verstärktes flächiges Implantat
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DE19959088A1 (de) * 1999-12-08 2001-06-13 Inst Textil & Faserforschung Medizintechnisches Produkt, Verfahren zu seiner Herstellung und Verwendung
DE10121193A1 (de) * 2001-04-30 2002-11-28 Ethicon Gmbh Flächiges Implantat
FR2846548B1 (fr) * 2002-11-04 2005-01-28 Sofradim Production Piece composite intermediaire pour faconnage de protheses de renfort
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Also Published As

Publication number Publication date
DE102010048710A1 (de) 2011-10-06
JP2013523225A (ja) 2013-06-17
WO2011120506A3 (de) 2012-02-23
WO2011120506A2 (de) 2011-10-06
US20130110245A1 (en) 2013-05-02
DE102010048710B4 (de) 2013-05-23
EP2552502A2 (de) 2013-02-06

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