WO2010123495A1 - Mécanisme de sécurité pour dispositif d'injection - Google Patents

Mécanisme de sécurité pour dispositif d'injection Download PDF

Info

Publication number
WO2010123495A1
WO2010123495A1 PCT/US2009/041224 US2009041224W WO2010123495A1 WO 2010123495 A1 WO2010123495 A1 WO 2010123495A1 US 2009041224 W US2009041224 W US 2009041224W WO 2010123495 A1 WO2010123495 A1 WO 2010123495A1
Authority
WO
WIPO (PCT)
Prior art keywords
injection device
injection
tissue interface
chamber
tissue
Prior art date
Application number
PCT/US2009/041224
Other languages
English (en)
Inventor
Michael H. Dutcher
Mikhail A. Zolotukhin
Anatoly Y. Loskutov
Original Assignee
Dutcher Michael H
Zolotukhin Mikhail A
Loskutov Anatoly Y
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dutcher Michael H, Zolotukhin Mikhail A, Loskutov Anatoly Y filed Critical Dutcher Michael H
Priority to PCT/US2009/041224 priority Critical patent/WO2010123495A1/fr
Publication of WO2010123495A1 publication Critical patent/WO2010123495A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • A61M2005/208—Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin

Definitions

  • This disclosure relates to a needle-free injector with safety mechanisms to prevent accidental discharge of medications that the needle-free injector will administer to a subject.
  • syringes and needles For many years, vaccination and administration of medicine has been accomplished by using syringes and needles. However, use of traditional syringes and needles increases the risk of accidental needle-sticks and disease transmission among injection recipients. In addition, if not administered with caution, syringes and needles may cause tissue damage at the site of injection, thereby creating lesions and scar tissue. Particularly with the use of needle injection of animals, the risk of accidental needlesticks and inadvertent self-injection increases. Also, injection site lesions may result in losses of tens of millions of dollars each year to meat producers from reduced grade and carcass trim. Further, during injection, needle tips may break causing residual needle fragments to remain in the subject.
  • a further drawback to traditional syringes and needles are the high costs when the units are provided for worldwide use. Many subjects, whether human or animal, have a strong aversion to needle injection. Other drawbacks are associated the traditional methods of delivering medications using needles and syringes. [0004] Alternative methods of delivering medication have been developed. Syringes and needles have been equipped with certain safety features to reduce the risk of needlesticks or accidental injection. Another method is to deliver medication using a needle-free injector.
  • a needle-free injector delivers medication by providing a strong, high pressure blast of the medication through a small orifice, which causes a minute stream of the medication to exit the orifice at a high rate of speed, thereby allowing the medication to penetrate into the skin and subcutaneous tissues.
  • one drawback of existing needle-free injectors is that they do not assist the user in making sure that proper contact with the subject to be injected is maintained during the injection process.
  • a needle-free injector having a contact mechanism that will come into contact with the subject, which restricts the needle-free injector from giving the injection to the subject until all of the conditions required by the contact mechanism are met.
  • FIG. 1 is a perspective view of an injection system in accordance with an embodiment of the present invention
  • FIG. 2 A is a cross-sectional view of the injection device of an embodiment of the present invention.
  • FIG. 2B is a cross-sectional view of the actuated injection device of an embodiment of the present invention.
  • FIG. 2C is a cross-sectional view of the non-actuated injection device of an embodiment of the present invention.
  • FIG. 3 is a cross-sectional view of an electronically operated injection device of an embodiment of the present invention.
  • FIG. 4 is a cross-sectional view of an pneumatically operated injection device of an embodiment of the present invention.
  • FIG. 1 depicts an injection system 10 for injecting a substance into a subject.
  • the injection system 10 includes a body 11, medicine supply tube 12, distal end 13, and proximal end 18.
  • the distal end 13 of the injection device has a tissue interface 14 through which the substance is expelled into a subject, and safety interfaces 15.
  • the safety interfaces 15 have to be collectively depressed into a distal end 13 of the injection device 10 to initiate the injection process or to transition the injection device 10 to a state where the injection device's injection process may be enabled and/or initiated.
  • the distal end 13 and/ or the proximal end 18 of the injection device 10 has pneumatic, mechanical or electrical actuators 16, which are connected with safety interfaces 15 by mechanical, electrical, pneumatic or other means, [0016]
  • Fig. 2A-B depicts a cross-sectional view of the injection system 10 for injecting a substance into a subject.
  • the injection system 10 includes a body 11, medicine supply tube (NOT SHOWN), distal end 17, and proximal end 15.
  • the body 11 of the injection system 10 has an internal cavity 16 through which the substance is delivered into a subject.
  • the proximal end 15 of the injection device 10 has a lever 12 that can be rotated on an axis 13.
  • the lever 12 has contact with safety interfaces 18 and transfer the axial movement of the safety interfaces 18 to injection actuator 14.
  • Fig. 2A an injection device 10 is ready for injection.
  • the injection device 10 is pressed against the subject 20 into which the substance is delivered. Tissue interface 19 comes in flush contact with the subject 20 and safety interfaces 18 are simultaneously depressed into a distal end 17 of the injection device 10.
  • the safety interface mechanism can incorporate an electronic dispatching mechanism that dispatches an electronic signal (as it is presented on Fig.
  • the injection device 10 has safety interfaces 18 that, when depressed, actuate independent sequentially placed electronic switches 21. Both switches have to be engaged simultaneously for the injection to occur.
  • the injection device 10 has safety interfaces 18 that, when depressed, actuate independent sequentially placed pneumatic valves 22. Both valves have to be actuated simultaneously for the injection process to be enabled and/or initiated.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention porte sur un dispositif d'injection équipé d'un mécanisme de sécurité qui, lorsqu'il est enclenché, initie le processus d'injection ou permet la transition du dispositif d'injection dans un état dans lequel le processus d'injection du dispositif d'injection peut être initié par d'autres moyens.
PCT/US2009/041224 2009-04-21 2009-04-21 Mécanisme de sécurité pour dispositif d'injection WO2010123495A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2009/041224 WO2010123495A1 (fr) 2009-04-21 2009-04-21 Mécanisme de sécurité pour dispositif d'injection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2009/041224 WO2010123495A1 (fr) 2009-04-21 2009-04-21 Mécanisme de sécurité pour dispositif d'injection

Publications (1)

Publication Number Publication Date
WO2010123495A1 true WO2010123495A1 (fr) 2010-10-28

Family

ID=43011370

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/041224 WO2010123495A1 (fr) 2009-04-21 2009-04-21 Mécanisme de sécurité pour dispositif d'injection

Country Status (1)

Country Link
WO (1) WO2010123495A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015150401A (ja) * 2014-02-19 2015-08-24 株式会社ダイセル 無針注射器

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6210359B1 (en) * 2000-01-21 2001-04-03 Jet Medica, L.L.C. Needleless syringe
US20020151839A1 (en) * 1998-10-14 2002-10-17 Sergio Landau Needle-less injection system
US20030187386A1 (en) * 2000-04-07 2003-10-02 Parsons J. Stuart Low cost disposable needleless injector system for variable and fixed dose applications
US20040106894A1 (en) * 2002-09-06 2004-06-03 Massachusetts Institute Of Technology Needleless drug injection device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020151839A1 (en) * 1998-10-14 2002-10-17 Sergio Landau Needle-less injection system
US6210359B1 (en) * 2000-01-21 2001-04-03 Jet Medica, L.L.C. Needleless syringe
US20030187386A1 (en) * 2000-04-07 2003-10-02 Parsons J. Stuart Low cost disposable needleless injector system for variable and fixed dose applications
US20040106894A1 (en) * 2002-09-06 2004-06-03 Massachusetts Institute Of Technology Needleless drug injection device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015150401A (ja) * 2014-02-19 2015-08-24 株式会社ダイセル 無針注射器

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