WO2010113564A1 - Dispositif de mesure d'un composant - Google Patents

Dispositif de mesure d'un composant Download PDF

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Publication number
WO2010113564A1
WO2010113564A1 PCT/JP2010/052642 JP2010052642W WO2010113564A1 WO 2010113564 A1 WO2010113564 A1 WO 2010113564A1 JP 2010052642 W JP2010052642 W JP 2010052642W WO 2010113564 A1 WO2010113564 A1 WO 2010113564A1
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WO
WIPO (PCT)
Prior art keywords
sampling tool
housing
case
component measuring
cylindrical
Prior art date
Application number
PCT/JP2010/052642
Other languages
English (en)
Japanese (ja)
Inventor
隆行 杉山
大祐 西内
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Publication of WO2010113564A1 publication Critical patent/WO2010113564A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/04—Constructional details of apparatus
    • A61B2560/0462—Apparatus with built-in sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/24—Hygienic packaging for medical sensors; Maintaining apparatus for sensor hygiene

Definitions

  • the present invention relates to a component measuring device that measures the amount and property of a predetermined component in a body fluid such as blood glucose level in blood, and in particular, removes a collection tool after collecting a body fluid and measuring the component. It is related with the collection tool discharge
  • Various body fluid component measuring devices are used to detect a predetermined component in body fluid and measure the amount and property of the predetermined component.
  • a blood glucose meter that measures glucose concentration in blood is used.
  • a collection tool disposal mechanism that can discard a used collection tool (chip) after measuring a blood glucose level without touching the collection tool.
  • a shape and structure that can easily clean dirt such as blood adhering to the apparatus main body.
  • Patent Document 1 As a device for solving such a problem, for example, there is an apparatus described in Patent Document 1.
  • the component measuring apparatus according to Patent Document 1 includes a case, a collection tool mounting unit, a detection unit, a control unit, a display unit, a battery installation unit, and first and second sealing means.
  • the storage space defined by the case main body, the lid, and the detection unit, and storing the control unit, the display unit, and the battery installation unit is sealed by the first and second sealing means. It is said.
  • the component measuring apparatus according to Patent Document 1 (hereinafter referred to as “first conventional example”) is expected to have the effect that it can be cleaned, disinfected, etc., and can be used safely and repeatedly.
  • Patent Document 2 describes a measurement apparatus that collects and measures a sample such as a body fluid.
  • the measuring apparatus according to Patent Document 2 is for electrochemically analyzing an analysis sample collected by a sensor having an electrode terminal formed at one end, and includes a sensor holding portion, a connection terminal, a discharge mechanism, and a brake means. It is characterized by providing.
  • second conventional example when the sensor is discharged, the sensor is discharged at a stable speed while controlling the amount of the sensor protruding from the measurement apparatus. did. Therefore, it is possible to prevent the sensor from being discharged at an unnecessarily high speed, and the patient and other operators can safely dispose of the sensor without directly touching the sensor on which a sample such as body fluid is spotted. The effect of being able to be expected is expected.
  • the eject member is held at the lower end of the case body so as to be able to advance and retract, and these are covered by the tip cover member.
  • a holder is fixed to the tip of the case body, and a chip mounting portion provided at the tip of the holder protrudes from the tip opening of the tip cover member and is exposed to the outside. While the chip is detachably mounted on the chip mounting portion, three pins are provided on the eject member in order to release the mounted chip. The three pins are formed so that the tips thereof face the tip openings, and in order to avoid contact with these pins, a pin opening is provided at the periphery of the tip openings.
  • the eject member is moved manually, and the tip is pushed out from the tip mounting portion by pressing the base end surface of the cylindrical portion of the tip with the three pins provided on the eject member.
  • the three pins are arranged in the portion corresponding to the cylindrical portion of the chip, and it is necessary to provide an opening at the periphery of the tip opening of the tip cover member in order to avoid interference with the pin. .
  • the tip of the pin is exposed to the outside. In this way, the tip cover member is provided with many gaps and depressions, and the tip of the pin is exposed to the outside.As a result, dirt attached to the tip cover member etc. enters the gap and the depression and is difficult to remove. There has been a problem that dirt may enter the inside of the apparatus.
  • the senor that is detachably attached to the connector is made of a thin flat plate member, and the push member is moved by operating the discharge lever at the rear end of the sensor. It was configured to discharge. Therefore, since the object to be discharged is different from the chip made of the cylindrical member of the present invention, the discharge mechanism cannot be used as the sampling tool discharge mechanism of the present invention.
  • the problem to be solved is that in the conventional component measuring apparatus as described above, the tip cover member has many gaps and depressions, and dirt attached to the tip cover member etc. enters and is difficult to remove. It is a point that dirt may enter the inside of the device. In addition, there is no small-sized and simple sampling tool discharge mechanism that matches the shape of the sampling tool (chip) used.
  • the present invention is a component measuring apparatus for measuring components in body fluids.
  • a housing having a torso that can be grasped by a person and provided with an opening at one end of the torso, and a collecting tool mounting part that is provided in the opening and is detachably mounted with a collecting tool that contains body fluid;
  • An eject member is provided that is slidably attached to the housing and that allows the sampling tool mounted on the sampling tool mounting portion to be slid to be detached from the sampling tool mounting portion.
  • the sampling tool has a cylindrical part inserted into the sampling tool mounting part, and the eject member has the main feature that it has a frame body part that is in surface contact or line contact with the end surface of the cylindrical part.
  • the present invention is characterized in that the frame body portion of the eject member is disposed inside the collection tool holding section that holds the collection tool, and slides between the collection tool holding section and the collection tool positioning section. Further, the present invention is characterized in that the cylindrical portion of the sampling tool is composed of a plurality of elastic pieces arranged in a cylindrical shape. The present invention is characterized in that the opening is opened on the distal end side of the bending portion provided on one side of the housing, and the operation portion of the eject member is arranged on the convex side of the intermediate portion of the bending portion.
  • the present invention is characterized in that an inner casing housed in the casing is provided, and a contact portion between the inner casing and the casing is liquid-tightly sealed with a first sealing member. Furthermore, the present invention is characterized in that the inner housing is provided with a battery housing portion in which a portable power source is housed, and the periphery of the battery housing portion is liquid-tightly sealed with a second sealing member. .
  • the present invention it is possible to minimize gaps and dents in the collection tool mounting portion of the housing, and it is easy to remove dirt attached to the housing, preventing the dirt from entering the inside of the apparatus, or effects. Can be suppressed. Further, it is possible to configure a small-sized and simple collecting tool discharge mechanism that matches the shape of the collecting tool (chip) used.
  • FIG. 6 is a cross-sectional view taken along line YY shown in FIG. 5 in a state in which a sampling tool (chip) is attached to the component measuring apparatus of the present invention.
  • FIG. 5 is an enlarged cross-sectional view taken along the line XX shown in FIG.
  • FIG. 6 is a cross-sectional view taken along the line YY shown in FIG.
  • FIG. 5 is an enlarged cross-sectional view taken along line XX shown in FIG. It is explanatory drawing of the detachment
  • FIG. 12A is a perspective view
  • FIG. 12B is a left side view
  • FIG. 12C is a front view
  • FIG. 12D is a bottom view, showing a first example of an eject member according to the component measuring apparatus of the present invention.
  • FIG. 12A is a perspective view
  • FIG. 12B is a left side view
  • FIG. 12C is a front view
  • FIG. 12D is a bottom view, showing a first example of an eject member according to the component measuring apparatus of the present invention.
  • FIG. 13A is a perspective view
  • FIG. 13B is a rear view
  • FIG. 13C is a side view
  • FIG. 13D is Z in FIG. 13C, showing a first embodiment of a sampling tool (chip) according to the component measuring apparatus of the present invention.
  • FIG. It is a disassembled perspective view which shows the example of 2nd Embodiment of the component measuring apparatus of this invention. It is explanatory drawing which expressed the sealing state by the sealing member by cross-sectioning the housing
  • 1 to 13 are views showing a blood glucose meter 1 according to a first embodiment of a component measuring apparatus of the present invention.
  • 14 and 15 are views showing a blood glucose meter 100 according to a second embodiment of the component measuring apparatus of the present invention.
  • the present invention is not limited to the blood glucose meter 1,100 shown in the first and second embodiments.
  • the blood glucose meter 1 shown in FIGS. 1 to 5 is operated by a doctor, a nurse, or a diabetic patient in a hand like a mobile phone, and its main function is to measure a blood glucose level in blood.
  • the device is capable of managing the measurement data of the blood sugar level.
  • This blood glucose meter 1 includes a housing 2 formed of a hollow container, a power supply unit 3 built in the housing 2, a measuring unit 4 for measuring a blood sugar level, input items, confirmation items, measurement results, and the like.
  • the display unit 5 is configured to include a display unit 5 and a control unit 6 that controls operation, display, and the like of the measurement unit 4 and the display unit 5.
  • the housing 2 is a three-dimensional body having a body 11 that is slightly elongated and easy to hold for a person so that a person can hold it with one hand and easily press the operation button of the operation section. It is made into a shape.
  • the housing 2 has an upper case 7 and a lower case 8 that are vertically stacked, and can be assembled and disassembled by a plurality of fixing screws 13 (see FIG. 1) while being vertically stacked.
  • the display unit 5 and the control unit 6 are disposed in the hollow chamber 12 of the body portion 11 of the housing 2, and the distal end side that is one side in the longitudinal direction of the hollow chamber 12.
  • the measuring unit 4 is arranged in A display unit 5 is attached to the upper case 7, and a power supply unit 3 is provided to the lower case 8.
  • the lower case 8 is provided with a battery storage portion 14 that opens to the lower surface side.
  • a button battery 19 as a portable power source is detachably stored in the battery storage portion 14.
  • the battery housing portion 14 is covered with a battery lid 20 that is detachably attached to the lower case 8 so as to be opened and closed.
  • the operation of the measuring unit 4 and the control unit 6 or the display of the display unit 5 is controlled by the power of the button-type battery 19.
  • the battery used for the power supply unit 3 is not limited to the button type battery when classified from the aspect of form, and a round battery, a square battery, or other forms can be used.
  • lithium ion batteries as well as alkaline batteries, manganese batteries, and other materials can be used when classified in terms of battery materials.
  • an opening window 15 having a substantially rectangular shape penetrating the front and back surfaces is provided at a substantially central portion of the upper case 7.
  • a liquid crystal cover 16 having a shape corresponding to the opening window 15 is fitted.
  • the entire upper surface of the liquid crystal cover 16 is covered with a front panel 17 that is formed to be appropriately larger than this.
  • the front panel 17 is large enough to cover the two switch tops 18 disposed on the upper surface of the upper case 7.
  • the switch top 18 is a member that connects the input portion 17a of the front panel 17 and the input switch 21 so that power can be transmitted.
  • the two switch tops 18 are respectively inserted into insertion holes 22 provided on the upper surface of the upper case 7, and the two input switches 21 can be turned on and off via these switch tops 18.
  • a liquid crystal panel 23 of the display unit 5 and a main wiring board 24 of the control unit 6 are arranged.
  • the main wiring board 24 is mounted with a microcomputer for executing a predetermined function set in advance, a storage device such as a ROM and a RAM in which a predetermined program is stored, a capacitor, a resistor, and other electronic components. ing.
  • a liquid crystal panel 23 is attached to the upper surface of the main wiring board 24 via two spacers 25.
  • the main wiring board 24 is fixed to the four support pillars 7a provided on the upper case 7 by fixing screws 44 at a plurality of positions.
  • the liquid crystal panel 23 is opposed to the lower surface of the liquid crystal cover 16 fixed to the upper case 7.
  • the two input switches 21 made of tact switches are mounted on the surface of the main wiring board 24 on the upper case 7 side, and the switches held in the upper case 7 at the input portions of the input switches 21.
  • the lower end of the top 18 faces.
  • input switches (not shown) (for time setting and post-meal mark) are disposed on the base end side of the input switch 21.
  • a notch 27 is provided on the back surface of the lower case 8 so that the input switch (not shown) faces the outside. The notch 27 is closed by a cover member (not shown).
  • the bending portion 28 is composed of a combination of an upper bending portion 28a formed of an inwardly U-shaped portion provided in the upper case 7 and a lower bending portion 28b formed of an outward U-shaped portion provided in the lower case 8.
  • the curved portion 28 that is curved toward the lower case 8 as a whole is formed by overlapping the upper curved portion 28a and the lower curved portion 28b. Accordingly, the opening 29 set at the distal end of the bending portion 28 is opened obliquely downward at a position slightly inclined toward the lower case 8 side with respect to the portion passing through the center of the housing 2.
  • the measuring unit 4 is disposed in the opening 29 of the housing 2.
  • a ring casing 31 is fixed to the opening 29 of the casing 2.
  • the ring housing 31 includes a fixing portion 31a for fixing to the housing 2 and a cylindrical shaft portion 31b formed integrally with the fixing portion 31a.
  • the fixed portion 31a has an end surface portion 31c that is developed inward so as to close the opening 29, and a cylindrical tube shaft portion 31b having a slightly smaller diameter is provided on the outer side at a substantially central portion of the end surface portion 31c. It is formed so as to protrude.
  • the fixing portion 31a is provided with a plurality of engaging claws (in the present embodiment, two locations on the upper and lower sides) 45 for fixing the ring casing 31 to the casing 2.
  • claw receiving portions 29 a are provided at two locations above and below the opening 29 of the housing 2.
  • the measuring unit 4 for measuring a blood component indicating a specific example of the specimen is disposed.
  • the measuring unit 4 includes a photometric block 33, an eject member 35, an eject operator 36, an inner ring 37, and the like.
  • the photometry block 33 is a device that optically measures a blood glucose level from the collected blood.
  • the photometric block 33 measures the color concentration of the blood sample and the red concentration of red blood cells, and quantifies the glucose concentration while correcting the glucose value obtained from the color concentration using the hematocrit value obtained from the red concentration.
  • the blood sugar level can be measured.
  • the photometric block 33 is supported and fixed to the housing 2.
  • the photometry block 33 has a flat base portion 33a and circular shaft portions 33b and 33c formed in a two-stage structure on the front side of the base portion 33a. .
  • a first shaft portion 33b having a large diameter is provided continuously with the base portion 33a, and a second shaft portion 33c having a small diameter is provided continuously with the first shaft portion 33b.
  • An irradiation port 38 for irradiating one test paper with light of two types of wavelengths is opened in the second shaft portion 33c of the photometry block 33.
  • the photometric block 33 is inserted inside the ring housing 31, and two shaft portions 33b and 33c are concentrically disposed inside the cylindrical shaft portion 31b.
  • an inner ring 37 is disposed inside the cylindrical shaft portion 31b, and a second shaft portion 33c is disposed opposite to the back side of the inner ring 37.
  • the inner ring 37 has a cylindrical portion 37a in which the through hole 41 is provided in the center, and a flange portion 37b provided so as to continuously extend radially outward on one end face side of the cylindrical portion 37a. ing.
  • the flange portion 37 b is fitted inside the cylindrical shaft portion 31 b of the ring housing 31, and the inner ring 37 is fixed to the ring housing 31 via the flange portion 37 b.
  • the cylindrical portion 37 a is disposed on the same axial center line inside the cylindrical shaft portion 31 b of the ring housing 31.
  • a space portion having a ring shape is formed between the fixed portion 31 a of the ring casing 31 and the cylindrical portion 37 a of the inner ring 37.
  • a frame body portion 61 of an eject member 35 described later slides in the longitudinal direction in the space portion having the ring shape.
  • the ring housing 31 and the inner ring 37 constitute a collection tool mounting portion 43 that can removably support the collection tool (chip) 50.
  • the cylindrical shaft portion 31b of the ring housing 31 functions as a sampling tool holding portion for fitting and fixing the sampling tool 50, and the inner ring 37 is brought into contact with the test paper 57 and the measurement block by the contact of the sampling tool 50.
  • the sampling tool positioning part for making the distance with 33 constant is comprised.
  • the collection tool 50 has a configuration as shown in FIGS. 13A to 13D. That is, the sampling tool 50 includes a base portion 51 formed in a disk shape, a nozzle portion 52 formed on one surface of the base portion 51, and a cylindrical portion 53 formed on the other surface of the base portion 51. It is made up of.
  • the outer diameter of the base portion 51 is formed to be approximately the same as the outer diameter of the cylindrical shaft portion 31b.
  • the nozzle portion 52 is erected at the center of the base portion 51, and a sampling hole 54 penetrating in the axial direction is provided at the center portion.
  • the tip of the nozzle portion 52 is tapered, and a concave groove 52a for facilitating the suction of the specimen is provided on the tip surface.
  • the cylindrical portion 53 of the sampling tool 50 is formed in a size that matches the space of the sampling tool mounting portion 43, and its outer diameter is a size that can fit into the hole of the cylindrical shaft portion 31b.
  • the inner diameter is large enough to cover the cylindrical portion 37a.
  • a plurality of engaging claws (four in this embodiment) 55 made of elastic pieces are provided at the tip of the cylindrical portion 53, and a protrusion 32 is provided on the inner peripheral surface of the cylindrical shaft portion 31b. Yes.
  • the engaging claw 55 of the present embodiment is formed as an arc-shaped convex portion that is continuous in the circumferential direction, and a chevron-shaped convex portion 55a for increasing frictional resistance is provided on the outer peripheral surface thereof.
  • a test paper storage portion 56 communicated with the collection hole 54 is provided.
  • the test paper storage unit 56 stores a test paper 57 that collects blood and holds a predetermined amount of blood. By irradiating the blood held on the test paper with the predetermined light emitted from the photometric block 33, the components in the blood can be measured.
  • the inner surface of the cylindrical portion 53 of the sampling tool 50 has a step, and the end of the inner ring 37 abuts on this step, whereby the sampling tool 50 is accurately positioned on the photometric block 33. That is, the inner ring 37 functions as a sampling tool positioning unit.
  • An eject member 35 is provided to detach the sampling tool 50 mounted on the sampling tool mounting portion 43.
  • the eject member 35 has a configuration as shown in FIGS. 12A to 12D.
  • the eject member 35 includes a frame body portion 61 that is pushed out by directly contacting the collection tool 50, and a sliding plate 62 that is fixed to the frame body portion 61 and is slid by a predetermined distance.
  • the frame portion 61 is configured by opposing two arc pieces 61a, 61a curved in an arc shape in the left-right direction.
  • the frame portion 61 is movably attached to the first circular shaft portion 33b of the photometry block 33, and is moved forward and backward by a predetermined distance in the axial direction outside the circular shaft portion 33b.
  • the sliding plate 62 of the eject member 35 is shaped such that a midway portion in the longitudinal direction is bent at 90 degrees, and a fixed portion 62a is provided on one side of the bent portion, and on the other side of the bent portion.
  • a connecting portion 62b is provided.
  • the fixing portion 62a is formed as a U-shaped member having a size corresponding to the pair of arcuate plates 61a and 61a constituting the frame body portion 61. Then, a pair of arc plates 61a and 61a are erected so as to protrude to the opposite side of the connecting portion 62b on one surface of the fixed portion 62a.
  • An insertion hole 63 for connecting to the eject manipulator 36 is provided at a substantially central portion of the connecting portion 62b.
  • the eject operator 36 is fixed to the eject member 35 in a state as shown in FIG.
  • the eject operator 36 is provided so as to be exposed to the outside on the convex side of the curved portion 28 of the upper case 7. Therefore, as shown in FIG. 1, the upper case 7 is provided with a long hole 65 for allowing the eject operator 36 to move.
  • the elongated hole 65 is linearly extended by a predetermined length in the front-rear direction of the housing 2, and the leg portion 36a of the eject operator 36 is slidably engaged.
  • a screw hole is provided on the back surface of the eject operation element 36, and is fixed to the eject member 35 by being tightened by a fixing screw 66 inserted into the insertion hole 63 of the sliding plate 62. .
  • a ring-shaped spacer 67 is attached to the fixing screw 66, and a compression coil spring 68 is interposed between the spacer 67 and the sliding plate 62.
  • the eject member 35 is always urged rearward away from the inner ring 37 by being pulled by a tension coil spring 69 shown in FIG.
  • One end of the tension coil spring 69 is latched in a spring receiving hole 63 b provided in the sliding plate 62, and the other end is latched on a spring receiving portion of the housing 2.
  • the collection tool case 70 is used when the collection tool 50 is attached to or removed from the collection tool attachment portion 43.
  • the collection tool case 70 is provided with a collection tool storage portion that can store the collection tool 50.
  • the collection tool 50 is attached to the collection tool case 70 in advance, and the collection tool case 70 is put on the collection tool mounting portion 43 so that the collection tool 50 is automatically attached to the collection tool mounting portion 43 due to the difference in fitting force. Can be installed.
  • the sampling tool case 70 in which the sampling tool 50 is stored in the sampling tool storage part is put on the sampling tool mounting part 43, and the sampling tool case 70 is pushed to a predetermined depth.
  • the cylindrical portion 53 of the sampling tool 50 is inserted into the cylindrical shaft portion 31 b that is opened in a ring shape, and the four engaging claws 55 provided at the tip of the cylindrical portion 53 are connected to the cylindrical shaft portion 31 b of the ring housing 31.
  • the collection tool 50 is held and fixed by the collection tool mounting portion 43 by the holding force generated between the cylindrical shaft portion 31 b and the cylindrical portion 53.
  • the attachment force (fitting force) of the collection tool 50 to the collection tool case 70 is weak, when the collection tool case 70 is pulled, the collection tool case 70 is held by the collection tool mounting portion 43 while the collection tool case 70 is held. 50. Thereby, the attaching operation of the collection tool 50 is completed, and in this state, it is possible to measure a blood sugar level or the like in the blood as the sample.
  • the blood glucose meter 1 having such a sampling tool discharge mechanism can be used as follows, for example.
  • the fingertip is punctured with a dedicated puncture device, and a small amount (eg, about 0.3 to 1.5 ⁇ L) of blood is allowed to flow out from the puncture portion onto the skin.
  • the tip of the nozzle portion 52 of the sampling tool 50 attached to the tip of the blood glucose meter 1 is brought into contact with the small amount of blood that has risen at the fingertip.
  • the blood at the fingertip enters the collection hole 54 via the concave groove 52 a, is sucked by capillary action, flows inward, and reaches the center of the test paper 57 accommodated in the cylindrical portion 53.
  • the blood that reaches the test paper 57 soaks into the inside from the surface and spreads radially outward.
  • the glucose in the blood and the reagent carried on the test paper 57 start to react and color according to the amount of glucose.
  • the blood glucose level can be determined by measuring (coloring) the color of the colored test paper 57 and measuring the intensity (shading) of the coloration.
  • the sampling tool 50 When the sampling tool 50 is ejected from the sampling tool mounting portion 43 after the measurement is completed, for example, the user grips the trunk 11 and aligns the thumb with the depression of the eject operating element 36 and presses the eject operating element 36 forward. It is only necessary to slide the eject member 35 forward. At this time, when the eject operator 36 is pressed forward from the state shown in FIGS. 6 and 7, the slide member 35 integrated therewith is moved by the same distance. As a result, as shown in FIGS. 8 and 9, the ends of the pair of frame portions 61 provided at the ends of the eject member 35 press the ends of the engaging claws 55 of the sampling tool 50 forward, and the sampling tool 50. Is removed from the collection tool mounting portion 43. Thereby, the collection tool 50 can be discarded in a predetermined disposal container.
  • the casing 2 is provided with a bending portion 28, an eject operator 36 is disposed on the convex side of the bending portion 28, and a sampling tool mounting portion 43 is disposed at the tip of the bending portion 28, so that the ejection operation is performed.
  • the sampling tool 50 is released in the direction in which the child 36 moves. Therefore, the aim of the discharge direction can be set in a desired space portion, and the sampling tool 50 can be easily and reliably discharged into the space portion. Therefore, the disposal of the collection tool 50 can be performed easily and quickly while maintaining safety without touching the collection tool 50.
  • the collection tool 50 can be discarded using the collection tool case 70.
  • the collection tool case 70 in which the collection tool storage section is empty is put on the collection tool 50 mounted on the collection tool mounting section 43.
  • the eject manipulator 36 is pressed to slide the eject member 35 forward.
  • the collection tool 50 is pushed forward as described above, and is removed from the collection tool mounting portion 43 while being stored in the collection tool case 70. Accordingly, the disposal of the sampling tool 50 can be performed safely, easily and quickly without the operator touching the sampling tool 50.
  • FIG. 14 and 15 show a second example of the blood glucose meter according to the component measuring apparatus of the present invention.
  • This blood glucose meter 100 is configured such that the middle case 9 is provided in the blood glucose meter 1 described in the above embodiment, and the sealing performance of the middle case 9 is improved.
  • the second embodiment is different from the first embodiment mainly in that an inner case 9 and a barcode unit 110 are provided. Therefore, here, the middle case 9 and the barcode unit 110 will be mainly described, and the same parts are denoted by the same reference numerals, and redundant description will be omitted.
  • the blood glucose meter 100 shown in FIG. 14 is operated by a doctor, nurse or the like in a hand like a mobile phone, and its main function is to measure blood glucose level in the blood, This is a device that can confirm the name of the patient related to the measurement, the drug to be administered, and the management of the measurement data.
  • the blood glucose meter 100 includes a housing 2A made of a hollow container, a power supply unit 3A built in the housing 2A, a measuring unit 4 for measuring a blood glucose level, input items, confirmation items, measurement results, and the like.
  • the display unit 5 is configured to include a display unit 5 and a control unit 6 that controls operation, display, and the like of the measurement unit 4 and the display unit 5.
  • the housing 2 ⁇ / b> A includes an upper case 7 ⁇ / b> A, a lower case 8 ⁇ / b> A, and a middle case 9, and the middle case 9 is accommodated in the recess of the lower case 8 ⁇ / b> A so
  • the upper case 7A is superposed on the lower case 8A.
  • the upper case 7A is provided with a large number of insertion holes (six in this embodiment) 22, and six input switches 101 are fitted in the respective insertion holes 22.
  • the six input switches 101 are mounted on the switch wiring board 102.
  • a barcode unit 110 is disposed below the switch wiring board 102.
  • the barcode unit 110 is a device that scans the barcode of an identification tag such as a patient or a nurse and reads patient or user information.
  • the barcode unit 110 is attached to the housing 2 with the light emitting / receiving portion facing the notch 27 provided on the back surface of the housing.
  • a liquid crystal cover 16 and a liquid crystal panel 23 are attached to the opening window 15 of the upper case 7A.
  • the lower case 8A is provided with a battery mounting portion 104 on which a rectangular secondary battery 103 constituting the power supply portion is mounted.
  • the battery mounting portion 104 is formed as a rectangular cradle corresponding to the shape of the battery used.
  • Other configurations of the lower case 8A are substantially the same as those of the lower case 8.
  • a middle case 9 showing a specific example of the inner housing having a shape corresponding to the shape of the concave portion on the bottom surface is accommodated in the concave portion of the lower case 8A.
  • the middle case 9 has a battery housing portion 105 having a shape corresponding to the battery placement portion 104 of the lower case 8 ⁇ / b> A and opened at the bottom surface.
  • the battery storage unit 105 stores the secondary battery 103 mounted on the battery mounting unit 104. That is, the battery mounting portion 104 plays a role like a lid that closes the opening of the battery storage portion 105, and between the middle case 9 and the lower case 8A in order to improve the liquid tightness of the opening.
  • the second sealing member 106 is interposed.
  • a notch 113 is provided corresponding to the notch 27 of the lower case 8A.
  • the second sealing member 106 for example, an O-ring can be applied, and the O-ring surrounds the battery mounting portion 103 endlessly.
  • the battery housing portion 105 is fixed to the second sealing member 106 by utilizing the sealing property when the periphery of the battery housing portion 105 of the middle case 9 is brought into contact with the entire surface and the O-ring is compressed. It is liquid-tight.
  • a first sealing member 107 for improving liquid tightness with the upper case 7 ⁇ / b> A is attached to the upper surface of the outer peripheral edge of the middle case 9.
  • an O-ring can be applied as the first sealing member 107.
  • a circular groove-shaped lower fitting groove 108 that is continuous in the circumferential direction is provided on the upper surface of the outer peripheral edge of the middle case 9. Yes.
  • a circular groove-like upper fitting groove 109 that is disposed at a position corresponding to the lower fitting groove 108 and is continuous in the circumferential direction is provided on the inner surface of the upper case 7A.
  • first sealing member 107 and the second sealing member 106 for example, nitrile rubber, silicon rubber, acrylic rubber, and other various sealing materials can be used.
  • a space 111 for accommodating the liquid crystal panel 23, the barcode unit 110, and the like is provided on the upper surface of the middle case 9.
  • a photometric case 34 configured in a cylindrical shape is provided around the photometric block 33, and the waterproofness is enhanced by covering the photometric block 33.
  • Numeral 112 shown in FIG. 14 is a scan button.
  • the scan button 112 is an on / off switch for scanning barcode information using the barcode unit 110.
  • the secondary battery 103 for example, a lithium ion battery or the like can be used.
  • ABS resin acrylonitrile butadiene styrene resin
  • the middle case 9 can be used as the material of the upper case 7, 7A, the lower case 8, 8A, the middle case 9, and the ring housing 31.
  • various engineering plastics having a certain degree of strength and durability can be used.
  • the rear end portion of the sampling tool is pressed by the pair of curved frame parts, so that the structure of the pressing portion is increased while increasing the strength.
  • the push-out member for detaching the collection tool from the collection tool mounting part and its through hole are exposed to the outside. Therefore, it is possible to prevent or suppress the entry of a specimen such as blood into the apparatus.
  • the sealing member it is possible to improve the sealing performance between the housings and effectively prevent the specimen from entering the part other than the measurement part.
  • the component measuring apparatus of the present invention is not limited to the above-described embodiment, and various modifications and changes can be made in the configuration, shape, material, and the like without departing from the configuration of the present invention. Needless to say.
  • blood has been described as a body fluid.
  • the present invention is not limited to this, and may be lymph fluid, spinal fluid, saliva, or the like.
  • glucose blood glucose level
  • glucose blood glucose level
  • examples thereof include cholesterol, uric acid, creatinine, lactic acid, hemoglobin (occult blood).
  • cholesterol may be various alcohols, various sugars, various proteins, various vitamins, various inorganic ions such as sodium, and environmental hormones such as PCB and dioxin.
  • the amount of the predetermined component has been described. However, the property of the predetermined component may be measured, and both the amount and the property of the predetermined component may be measured. There may be.
  • forms two circular arc shape installed facing each other was demonstrated, it can comprise as a combination of three or more members. Further, instead of the arc shape, it can be configured as a U-shaped or L-shaped member.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne un dispositif de mesure d'un composant. Dans les dispositifs classiques de mesure d'un composant, de multiples espaces et creux sont prévus dans un élément de couvercle d'extrémité frontale, les saletés qui adhèrent à l'élément de couvercle frontal et analogues sont difficiles à éliminer et les saletés pénètrent parfois dans le dispositif. L'invention concerne un glucomètre (1) destiner à mesurer un composant dans le sang. Le glucomètre est muni d'un boîtier (2) qui comprend une partie de corps (11) qui peut être saisie par une personne et une ouverture (29) prévue à une extrémité de la partie de corps, une partie de montage d'un instrument de recueillement (43) sur laquelle un instrument de recueillement (embout) (50) qui est prévu dans l'ouverture et abrite un échantillon est monté amovible, et un élément d'éjection (35) qui est attaché coulissant avec le boîtier et détache l'instrument de recueillement de la partie de montage d'un instrument de recueillement en poussant l'instrument de recueillement monté sur la partie de montage d'un instrument de recueillement par un mouvement de coulissement. L'instrument de recueillement (50) comprend une partie cylindrique (53) insérée dans la partie de montage d'un instrument de recueillement (43) et l'élément d'éjection comprend une paire de parties de cadre (61, 61) qui est en contact linéaire avec la face frontale de la partie cylindrique.
PCT/JP2010/052642 2009-03-31 2010-02-22 Dispositif de mesure d'un composant WO2010113564A1 (fr)

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JP2009085578A JP5514464B2 (ja) 2009-03-31 2009-03-31 成分測定装置
JP2009-085578 2009-03-31

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014045347A1 (fr) * 2012-09-19 2014-03-27 テルモ株式会社 Dispositif de mesure de composant
JP2015508485A (ja) * 2011-09-20 2015-03-19 セラジェムメディシス インコーポレイテッドＣｅｒａｇｅｍ Ｍｅｄｉｓｙｓ Ｉｎｃ． モジュール型バイオセンサー
WO2015146238A1 (fr) * 2014-03-27 2015-10-01 テルモ株式会社 Appareil de mesure d'élément constitutif

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2631552B1 (fr) 2010-10-18 2021-03-31 Mitsubishi Electric Corporation Dispositif de commande de climatiseur, procédé de commande de climatiseur et programme
WO2013042536A1 (fr) * 2011-09-20 2013-03-28 テルモ株式会社 Dispositif de mesure de composants

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Publication number Priority date Publication date Assignee Title
JPH1019888A (ja) * 1996-07-02 1998-01-23 Terumo Corp 血液検査具及び血液検査測定器
JPH10148635A (ja) * 1996-08-09 1998-06-02 Lifescan Inc リモートドーズ式分析物濃度計器
WO2008087876A1 (fr) * 2007-01-19 2008-07-24 Terumo Kabushiki Kaisha Appareil de mesure de composant
JP2009025316A (ja) * 2008-09-30 2009-02-05 Terumo Corp 成分測定装置

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JP2004290477A (ja) * 2003-03-27 2004-10-21 Terumo Corp 成分測定装置および成分測定キット
JP3134339U (ja) * 2007-05-31 2007-08-09 テルモ株式会社 穿刺器具セット及び穿刺装置

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Publication number Priority date Publication date Assignee Title
JPH1019888A (ja) * 1996-07-02 1998-01-23 Terumo Corp 血液検査具及び血液検査測定器
JPH10148635A (ja) * 1996-08-09 1998-06-02 Lifescan Inc リモートドーズ式分析物濃度計器
WO2008087876A1 (fr) * 2007-01-19 2008-07-24 Terumo Kabushiki Kaisha Appareil de mesure de composant
JP2009025316A (ja) * 2008-09-30 2009-02-05 Terumo Corp 成分測定装置

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015508485A (ja) * 2011-09-20 2015-03-19 セラジェムメディシス インコーポレイテッドＣｅｒａｇｅｍ Ｍｅｄｉｓｙｓ Ｉｎｃ． モジュール型バイオセンサー
WO2014045347A1 (fr) * 2012-09-19 2014-03-27 テルモ株式会社 Dispositif de mesure de composant
WO2015146238A1 (fr) * 2014-03-27 2015-10-01 テルモ株式会社 Appareil de mesure d'élément constitutif
JPWO2015146238A1 (ja) * 2014-03-27 2017-04-13 テルモ株式会社 成分測定装置
US10451629B2 (en) 2014-03-27 2019-10-22 Terumo Kabushiki Kaisha Component measuring device

Also Published As

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JP5514464B2 (ja) 2014-06-04
JP2010233845A (ja) 2010-10-21

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