WO2010079910A3 - 기능성 성분을 함유하는 당뇨 또는 당뇨 합병증의 예방 또는 치료 효능을 가지는 시력보호용 조성물 - Google Patents

기능성 성분을 함유하는 당뇨 또는 당뇨 합병증의 예방 또는 치료 효능을 가지는 시력보호용 조성물 Download PDF

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WO2010079910A3
WO2010079910A3 PCT/KR2009/007732 KR2009007732W WO2010079910A3 WO 2010079910 A3 WO2010079910 A3 WO 2010079910A3 KR 2009007732 W KR2009007732 W KR 2009007732W WO 2010079910 A3 WO2010079910 A3 WO 2010079910A3
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diabetes
eyesight
extract
functional components
complications
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PCT/KR2009/007732
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French (fr)
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WO2010079910A2 (ko
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임병우
어광
전윤희
정용준
최세영
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건국대학교 산학협력단
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Priority to US13/143,466 priority Critical patent/US8455018B2/en
Publication of WO2010079910A2 publication Critical patent/WO2010079910A2/ko
Publication of WO2010079910A3 publication Critical patent/WO2010079910A3/ko

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
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    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482—Cassia, e.g. golden shower tree
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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Abstract

본 발명은 당뇨 또는 당뇨 합병증의 예방 또는 치료 효능을 가지는 시력보호용 조성물에 관한 것으로서, 더욱 상세하게는 칼슘, 비타민 A, 비타민 C 및 비타민 D의 기능성 성분을 필수적으로 포함하며, 이에 더하여 구기자 추출물, 황기 추출물, 결명자 추출물, 둥글레 추출물 및 복분자 추출물로 이루어진 식물 유래 추출물을 1종 이상 추가로 함유하는 것을 특징으로 하는 당뇨 또는 당뇨 합병증의 예방 또는 치료 효능을 가지는 시력보호용 조성물에 관한 것이다. 본 발명의 기능성 성분을 함유하는 조성물은 염증인자 발현을 유의적으로 억제하며, JAK-STAT를 경유한 Th1/Th2 세포의 사이토카인의 발현을 억제 및 조절할 뿐만 아니라, 당뇨 합병증인 당뇨 망막병증에서의 STAT3의 발현을 유의적으로 억제함으로써, 당뇨 또는 당뇨 합병증의 예방 또는 치료 효능을 가지는 시력보호용 조성물로 유용하게 이용될 수 있다.
PCT/KR2009/007732 2009-01-08 2009-12-23 기능성 성분을 함유하는 당뇨 또는 당뇨 합병증의 예방 또는 치료 효능을 가지는 시력보호용 조성물 WO2010079910A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US13/143,466 US8455018B2 (en) 2009-01-08 2009-12-23 Vision-protecting composition with prophylactic and therapeutic activity against diabetes or diabetic complications

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090001356A KR101091596B1 (ko) 2009-01-08 2009-01-08 기능성 성분을 함유하는 당뇨 또는 당뇨 합병증의 예방 또는 치료 효능을 가지는 시력보호용 조성물
KR10-2009-0001356 2009-01-08

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WO2010079910A2 WO2010079910A2 (ko) 2010-07-15
WO2010079910A3 true WO2010079910A3 (ko) 2010-10-07

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PCT/KR2009/007732 WO2010079910A2 (ko) 2009-01-08 2009-12-23 기능성 성분을 함유하는 당뇨 또는 당뇨 합병증의 예방 또는 치료 효능을 가지는 시력보호용 조성물

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US (1) US8455018B2 (ko)
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CN104367833A (zh) * 2014-11-08 2015-02-25 欧阳永辉 一种治疗糖尿病的中药
CN104491179A (zh) * 2014-12-10 2015-04-08 常州诺瑞格纳米科技有限公司 一种护眼保健品
CN105105272A (zh) * 2015-09-14 2015-12-02 李加义 一种中年女性用减肥饮料
KR102121915B1 (ko) 2018-09-03 2020-06-11 한국과학기술연구원 결명 새싹 유래 나프토파이론 유도체를 포함하는 신경세포 보호용 조성물
KR102169240B1 (ko) 2020-02-28 2020-10-23 한국과학기술연구원 결명 새싹 유래 나프토파이론 유도체를 포함하는 신경세포 보호용 조성물

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Publication number Publication date
WO2010079910A2 (ko) 2010-07-15
KR20100082054A (ko) 2010-07-16
KR101091596B1 (ko) 2011-12-13
US8455018B2 (en) 2013-06-04
US20110268827A1 (en) 2011-11-03

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