WO2010058984A2 - Antioxidant composition containing extract of processed chrysanthemum indicum or citrus unshiu peel - Google Patents
Antioxidant composition containing extract of processed chrysanthemum indicum or citrus unshiu peel Download PDFInfo
- Publication number
- WO2010058984A2 WO2010058984A2 PCT/KR2009/006837 KR2009006837W WO2010058984A2 WO 2010058984 A2 WO2010058984 A2 WO 2010058984A2 KR 2009006837 W KR2009006837 W KR 2009006837W WO 2010058984 A2 WO2010058984 A2 WO 2010058984A2
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- WO
- WIPO (PCT)
- Prior art keywords
- extract
- chrysanthemum indicum
- citrus unshiu
- unshiu peel
- unprocessed
- Prior art date
Links
- 239000000284 extract Substances 0.000 title claims abstract description 115
- 239000000203 mixture Substances 0.000 title claims abstract description 95
- 241000555678 Citrus unshiu Species 0.000 title claims abstract description 79
- 240000005250 Chrysanthemum indicum Species 0.000 title claims abstract description 76
- 235000018959 Chrysanthemum indicum Nutrition 0.000 title claims abstract description 76
- 230000003078 antioxidant effect Effects 0.000 title claims abstract description 37
- 239000003963 antioxidant agent Substances 0.000 title claims abstract description 23
- 239000002537 cosmetic Substances 0.000 claims abstract description 31
- 238000000034 method Methods 0.000 claims abstract description 8
- 239000004480 active ingredient Substances 0.000 claims abstract description 7
- 241000196324 Embryophyta Species 0.000 claims description 33
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
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- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 6
- 239000002904 solvent Substances 0.000 claims description 6
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 4
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- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 description 18
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 12
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- 230000000052 comparative effect Effects 0.000 description 11
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- 229920001214 Polysorbate 60 Polymers 0.000 description 4
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 4
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- CUNWUEBNSZSNRX-RKGWDQTMSA-N (2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol;(z)-octadec-9-enoic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O CUNWUEBNSZSNRX-RKGWDQTMSA-N 0.000 description 3
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- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
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- 230000003647 oxidation Effects 0.000 description 3
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- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 description 3
- 229920002125 Sokalan® Polymers 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 235000013871 bee wax Nutrition 0.000 description 2
- 229940092738 beeswax Drugs 0.000 description 2
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- 230000002401 inhibitory effect Effects 0.000 description 2
- GSGDTSDELPUTKU-UHFFFAOYSA-N nonoxybenzene Chemical compound CCCCCCCCCOC1=CC=CC=C1 GSGDTSDELPUTKU-UHFFFAOYSA-N 0.000 description 2
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- 210000000952 spleen Anatomy 0.000 description 2
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- 238000003860 storage Methods 0.000 description 2
- 239000001100 (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one Substances 0.000 description 1
- HIXDQWDOVZUNNA-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxychromen-4-one Chemical compound C=1C(OC)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(OC)C(OC)=C1 HIXDQWDOVZUNNA-UHFFFAOYSA-N 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
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- 208000007882 Gastritis Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- QUQPHWDTPGMPEX-UHFFFAOYSA-N Hesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(COC4C(C(O)C(O)C(C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-UHFFFAOYSA-N 0.000 description 1
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- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
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- QUQPHWDTPGMPEX-UTWYECKDSA-N aurantiamarin Natural products COc1ccc(cc1O)[C@H]1CC(=O)c2c(O)cc(O[C@@H]3O[C@H](CO[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)cc2O1 QUQPHWDTPGMPEX-UTWYECKDSA-N 0.000 description 1
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- 229940021231 clearskin Drugs 0.000 description 1
- APSNPMVGBGZYAJ-GLOOOPAXSA-N clematine Natural products COc1cc(ccc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 APSNPMVGBGZYAJ-GLOOOPAXSA-N 0.000 description 1
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- 201000006549 dyspepsia Diseases 0.000 description 1
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- 229930003944 flavone Natural products 0.000 description 1
- -1 flavone glycoside Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 229940025878 hesperidin Drugs 0.000 description 1
- VUYDGVRIQRPHFX-UHFFFAOYSA-N hesperidin Natural products COc1cc(ccc1O)C2CC(=O)c3c(O)cc(OC4OC(COC5OC(O)C(O)C(O)C5O)C(O)C(O)C4O)cc3O2 VUYDGVRIQRPHFX-UHFFFAOYSA-N 0.000 description 1
- QUQPHWDTPGMPEX-QJBIFVCTSA-N hesperidin Chemical compound C1=C(O)C(OC)=CC=C1[C@H]1OC2=CC(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO[C@H]4[C@@H]([C@H](O)[C@@H](O)[C@H](C)O4)O)O3)O)=CC(O)=C2C(=O)C1 QUQPHWDTPGMPEX-QJBIFVCTSA-N 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- ARGKVCXINMKCAZ-UHFFFAOYSA-N neohesperidine Natural products C1=C(O)C(OC)=CC=C1C1OC2=CC(OC3C(C(O)C(O)C(CO)O3)OC3C(C(O)C(O)C(C)O3)O)=CC(O)=C2C(=O)C1 ARGKVCXINMKCAZ-UHFFFAOYSA-N 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 239000003642 reactive oxygen metabolite Substances 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
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- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
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- 230000002087 whitening effect Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Definitions
- the present invention relates to an antioxidant cosmetic composition, and more particularly to an antioxidant cosmetic composition containing, as an active ingredient, either an extract of at least one of Chrysanthemum indicum and Citrus unshiu peel, processed using a medicinal herb processing technique, or a mixture of said extract and an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel.
- a medicinal herb processing technique that is a traditional Chinese medicine manufacturing technique is called “Po-je”, “Hap-hwa”, “Hap-yak”, “Su-chi”, “Po-ja”, “Bub- je” and “Su-sa” in Korean.
- This technique can be defined as a medicine manufacturing technique of changing the inherent properties of medicinal herbs by processing the medicinal herbs on the basis of the Chinese medicine theory.
- the objects of processing medicinal herbs are to clarify medicines, facilitate the storage of medicines, reduce or remove the toxicity or side effects of medicines, change the properties of medicines to make the medicines more effective, enhance the therapeutic effects of medicines, and the offensive odor and taste of medicines to facilitate the intake of the medicines.
- the present inventors have conducted studies on natural materials having excellent antioxidant effects and, as a result, have found that, when a cosmetic composition is prepared using an extract of processed Chrysanthemum indicum or Citrus unshiu peel alone or in a mixture with an extract of unprocessed Chrysanthemum indicum or Citrus unshiu peel, the prepared composition shows a very excellent antioxidant effect, thereby completing the present invention.
- the present invention provides an antioxidant cosmetic composition containing, as an active ingredient, an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel.
- the present invention provides an antioxidant cosmetic composition containing a mixture of an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel and an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel.
- the cosmetic composition according to the present invention contains an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel alone or in a mixture with an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel, and thus has an excellent antioxidant effect of inhibiting DPPH oxidation.
- the present invention relates to an antioxidant cosmetic composition containing, as an active ingredient, an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel.
- the present invention also relates to an antioxidant cosmetic composition containing a mixture of an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel and an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel.
- the extract of the unprocessed plant which is mixed with the extract of the processed plant, is prepared from a plant different from a plant used to prepare the extract of the processed plant.
- a cosmetic composition according to a preferred embodiment of the present invention may contain, as active ingredients, an extract of unprocessed Chrysanthemum indicum and an extract of processed Citrus unshiu peel.
- extract of the unprocessed plant refers to an extract obtained by extracting Chrysanthemum indicum or Citrus unshiu peel with water or an organic solvent, which are conventionally used, without processing the plant.
- Chrysanthemum indicum which is used in the present invention is called "Hwang- kook” or "Gam-kook” in Korean.
- This plant grows mainly in the mountains and has short hairs throughout thereof. The stem reaches a height of 60-90 cm and is black, slender and long. Umbel flower heads open on the upper portion of the stem in September to October.
- Chinese medicine the plant is used to treat a fever, pneumonia, bronchitis, headache, gastritis, enteritis, a swell and the like.
- folk remedies the plant is attached to the affected area of the body in a pulverized state, or the affected area is washed with a liquid obtained by boiling the plant in water.
- the flower of Chrysanthemum indicum is used in a dried form, but the scope of the present invention is not limited thereto.
- Citrus unshiu peel which is used in the present invention refers to the peel of Citrus unshiuMarkovich and is generally obtained by harvesting and drying Citrus unshiu Markovich in October to November. It contains volatile essential oil, hesperidin (flavone glycoside), citric acid, vitamin B 1 and the like. Citrus unshiu peel is described in the literature as follows. Citrus unshiu peel is warm in nature, nontoxic, and hot and bitter in taste. It acts mainly in the spleen meridian and also acts in the lung meridian and the stomach meridian.
- the cosmetic composition according to the present invention is characterized in that it contains extracts prepared by processing each of Chrysanthemum indicum and Citrus unshiu peel and extracting each of the processed plants with an organic solvent.
- Extracts of Chrysanthemum indicum and Citrus unshiu peel can be prepared through a method comprising the steps of:
- step a) adding honey to Chrysanthemum indicum or Citrus unshiu peel and allowing the added honey to be absorbed into the plant for 30 minutes to 1 hour; [25] b) roasting the plant of step a) at 100-180 0 C for 10 minutes to 1 hour; and
- the honey in step a) is added in an amount of 20-30 wt% based on the weight of
- the extraction in step c) can be carried out according to any conventional method known in the art.
- an extract of each of the Chrysanthemum indicum and Citrus unshiu peel can be obtained by adding water or an organic solvent to each of Chrysanthemum indicum and Citrus unshiu peel, extracting the plant under reflux in the solvent, dipping the extract in the solvent, filtering the extract through filter cloth, centrifuging the filtered extract to separate it into the residue and the filtrate, and concentrating the separated filtrate under reduced pressure.
- the organic solvent which is used in the present invention can be selected from the group consisting of ethanol, methanol, butanol, ether, ethyl acetate, chloroform, and mixtures of these solvents with water.
- the extraction temperature is preferably 10-80 0 C, and the extraction time is preferably 6-24 hours. If the extraction temperature and time are out of the above- specified ranges, the extraction efficiency can be reduced or the changes in the components of the extract can occur.
- the extract may be macerated at room temperature according to a conventional method known in the art, and the macerated extract may be heated and filtered, thus obtaining a liquid- phase material.
- the extract may additionally be evaporated to remove the solvent or be spray-dried or freeze-dried.
- the cosmetic composition according to the present invention contains one or a mixture of the extracts of processed Chrysanthemum indicum and Citrus unshiu peel in an amount of 0.0001-30 wt% based on the total weight of the composition. If the content of the extract in the cosmetic composition is less than 0.0001 wt%, the antioxidant effect of the extract cannot be obtained, and if the content exceeds 30 wt%, the increase in the content will not lead to a significant increase in the effect of the extract and it will be difficult to maintain stability or prepare a formulation.
- the mixture of the extracts of processed Chrysanthemum indicum and Citrus unshiu peel is used, the mixture is preferably contained in an amount of 0.0001-30 wt% based on the total weight of the composition, and each of the components of the mixture may be used in an amount suitably selected from the range of 0.0001 to 30 wt% based on total weight of the composition.
- the extracts of processed Chrysanthemum indicum and Citrus unshiu peel are used at a weight ratio of 1 : 1.
- the cosmetic composition according to the present invention may contain, in addition to the extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel, an extract of at least one of unprocessed Chrysanthemum indicum and Citrus unshiu peel.
- the extract of unprocessed Chrysanthemum indicum or Citrus unshiu peel is prepared by extracting Chrysanthemum indicum or Citrus unshiu peel with water or an organic solvent without processing the plant, and the preparation process thereof is the same as the above-described extraction process of step c).
- the extract of the unprocessed plant, which is mixed with the extract of the processed plant is prepared from a plant different from a plant used to prepare the extract of the processed plant.
- the cosmetic composition according to the present invention contains an extract of at least one of processed Chrysanthemum indicum and Citrus unshiu peel and an extract of unprocessed Chrysanthemum indicum and Citrus unshiu peel in an amount of 0.0001-30 wt% based on the total weight of the composition. If the content of the extracts in the composition is less than 0.0001 wt%, the antioxidant effect of the extract cannot be obtained, and if the content exceeds 30 wt%, the increase in the content will not lead to a significant increase in the effects of the extracts and it will be difficult to maintain stability or prepare a formulation.
- the mixture of the extract of processed Chrysanthemum indicum or Citrus unshiu peel with the extract of unprocessed Chrysanthemum indicum or Citrus unshiu peel is used, the mixture is preferably contained in an amount of 0.0001-30 wt% based on the total weight of the composition, and each of the components of the mixture may be used in an amount suitably selected from the range of 0.0001 to 30 wt% based on the total weight of the composition.
- the extracts of the mixture are used in equal amounts.
- the cosmetic composition of the present invention can be formulated as a skin lotion, an astringent lotion, a milk lotion, a nourishing cream, a massage cream, an essence, a pack, a foundation, a lipstick or a powder foundation, but the scope of the present invention is not limited thereto.
- components other than the extract in the cosmetic composition can be suitably selected by a skilled in the art depending on the formulation or intended use of the cosmetic composition.
- Example 1 Preparation of extract of honev-roasted Citrus unshiu peel
- Example 4 Preparation of mixture of extracts of honey-roasted Citrus unshiu peel and unprocessed Chrysanthemum indicum
- Example 5 Preparation of mixture of extracts of honev-roasted Citrus unshiu peel and Chrysanthemum indicum
- IC 50 means the sample concentration at which the absorbance is reduced by 50%.
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Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011536264A JP5597642B2 (ja) | 2008-11-19 | 2009-11-19 | 炮製処理された甘菊及び陳皮の抽出物を含有する抗酸化用化粧料組成物 |
US13/128,700 US9700506B2 (en) | 2008-11-19 | 2009-11-19 | Antioxidant composition containing extract of processed Chrysanthemum indicum or Citrus unshiu peel |
CN2009801447024A CN102209525B (zh) | 2008-11-19 | 2009-11-19 | 含有经加工的野菊花或温州蜜柑皮的提取物的抗氧化剂组合物 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020080115369A KR101537293B1 (ko) | 2008-11-19 | 2008-11-19 | 포제 처리된 감국 또는 진피 추출물을 함유하는 항산화용 화장료 조성물 |
KR10-2008-0115369 | 2008-11-19 |
Publications (2)
Publication Number | Publication Date |
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WO2010058984A2 true WO2010058984A2 (en) | 2010-05-27 |
WO2010058984A3 WO2010058984A3 (en) | 2010-09-30 |
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Application Number | Title | Priority Date | Filing Date |
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PCT/KR2009/006837 WO2010058984A2 (en) | 2008-11-19 | 2009-11-19 | Antioxidant composition containing extract of processed chrysanthemum indicum or citrus unshiu peel |
Country Status (5)
Country | Link |
---|---|
US (1) | US9700506B2 (ko) |
JP (1) | JP5597642B2 (ko) |
KR (1) | KR101537293B1 (ko) |
CN (1) | CN102209525B (ko) |
WO (1) | WO2010058984A2 (ko) |
Cited By (1)
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JP2014533722A (ja) * | 2011-11-23 | 2014-12-15 | 株式会社アモーレパシフィックAmorepacific Corporation | 白色シマカンギク抽出物を含有する皮膚外用剤組成物 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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KR101480696B1 (ko) * | 2008-11-19 | 2015-01-09 | (주)아모레퍼시픽 | 사삼, 고본 및 생약 추출물을 포함하는 것을 특징으로 하는화장료 조성물 |
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JPS63170323A (ja) * | 1986-12-29 | 1988-07-14 | Cosmo Kaihatsu Kk | 抗アレルギ−剤 |
CN1102787A (zh) * | 1993-12-22 | 1995-05-24 | 屈天时 | 一种营养口服液的制备方法 |
JP3343708B2 (ja) * | 1995-07-14 | 2002-11-11 | 森谷健康食品株式会社 | 安眠用健康食品 |
US6726940B2 (en) * | 1997-09-18 | 2004-04-27 | Societe L'oreal S.A. | Use of at least one extract of the genus chrysanthemum for assisting skin and/or hair pigmentation |
JPH11246336A (ja) * | 1998-02-27 | 1999-09-14 | Ichimaru Pharcos Co Ltd | 活性酸素消去剤及び美肌化粧料組成物 |
ATE361083T1 (de) * | 2000-06-28 | 2007-05-15 | Kikkoman Corp | Antiallergische verbindungen und diese enthaltende medikamente, nahrungsmittel, getränke oder kosmetika sowie verfahren zu deren herstellung |
US20040223942A1 (en) * | 2003-03-06 | 2004-11-11 | Kao Corporation | Skin aging-preventing or improving agent |
CN1586248B (zh) * | 2004-10-15 | 2011-10-12 | 高思 | 保健饮品 |
KR101189989B1 (ko) * | 2005-06-30 | 2012-10-12 | (주)아모레퍼시픽 | 문형 추출물을 유효성분으로 함유하는 화장료 조성물 |
KR101483440B1 (ko) * | 2008-05-02 | 2015-01-19 | (주)아모레퍼시픽 | 포제를 활용한 약용식물 추출물 및 이를 함유하는 피부외용제 조성물 |
-
2008
- 2008-11-19 KR KR1020080115369A patent/KR101537293B1/ko active IP Right Grant
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2009
- 2009-11-19 JP JP2011536264A patent/JP5597642B2/ja not_active Expired - Fee Related
- 2009-11-19 US US13/128,700 patent/US9700506B2/en not_active Expired - Fee Related
- 2009-11-19 WO PCT/KR2009/006837 patent/WO2010058984A2/en active Application Filing
- 2009-11-19 CN CN2009801447024A patent/CN102209525B/zh active Active
Non-Patent Citations (4)
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BAE CHEON CHA ET AL.: 'Antioxidative effect of domestic plants' KOR. J. PHARMACOGN. vol. 28, no. 1, 1997, pages 15 - 20 * |
JUNG SIK YOU ET AL.: 'Quality characteristics of Chrysathemum indicum L. Flower Tea in relation to the number of pan-firing' J. KOREAN SOC. FOOD. SCI. NUTR. vol. 37, no. 5, 31 May 2008, pages 647 - 652 * |
KYUNG MI YOO ET AL.: 'Antioxidant activity and physicochemical Characteristics of Tangerine peel tea prepared with Cirtrus unshiu cultivated in Cheju' KOREAN J. FOOD COOKERY SCI. vol. 21, no. 3, June 2005, pages 354 - 359 * |
SUNG JE JUNG ET AL.: 'Screening for antioxidant activity of plant medicinal extracts' J. KOREAN SOC. APPL. BIOL. CHEM. vol. 47, no. 1, 2004, pages 135 - 140 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014533722A (ja) * | 2011-11-23 | 2014-12-15 | 株式会社アモーレパシフィックAmorepacific Corporation | 白色シマカンギク抽出物を含有する皮膚外用剤組成物 |
Also Published As
Publication number | Publication date |
---|---|
KR20100056282A (ko) | 2010-05-27 |
KR101537293B1 (ko) | 2015-07-16 |
CN102209525B (zh) | 2013-04-24 |
WO2010058984A3 (en) | 2010-09-30 |
US9700506B2 (en) | 2017-07-11 |
JP5597642B2 (ja) | 2014-10-01 |
CN102209525A (zh) | 2011-10-05 |
US20110223265A1 (en) | 2011-09-15 |
JP2012512813A (ja) | 2012-06-07 |
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