WO2010047516A3 - Ｎ-아세틸 글루코사민 생산능을 가지는 코리네박테리움 속 미생물과 이를 이용한 ｎ-아세틸 글루코사민 또는 글루코사민 생산 방법 - Google Patents

Ｎ-아세틸 글루코사민 생산능을 가지는 코리네박테리움 속 미생물과 이를 이용한 ｎ-아세틸 글루코사민 또는 글루코사민 생산 방법 Download PDF

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Publication number
WO2010047516A3
WO2010047516A3 PCT/KR2009/006063 KR2009006063W WO2010047516A3 WO 2010047516 A3 WO2010047516 A3 WO 2010047516A3 KR 2009006063 W KR2009006063 W KR 2009006063W WO 2010047516 A3 WO2010047516 A3 WO 2010047516A3
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WO
WIPO (PCT)
Prior art keywords
glucosamine
acetyl glucosamine
producing
acetyl
same
Prior art date
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PCT/KR2009/006063
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English (en)
French (fr)
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WO2010047516A2 (ko
Inventor
홍국기
정진수
신수안
박혜란
조재현
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씨제이제일제당 (주)
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Priority to JP2011533101A priority Critical patent/JP5677963B2/ja
Priority to CN200980145486.5A priority patent/CN103429731B/zh
Priority to EP09822192.2A priority patent/EP2348101B1/en
Priority to US13/125,181 priority patent/US9005957B2/en
Priority to ES09822192.2T priority patent/ES2584531T3/es
Publication of WO2010047516A2 publication Critical patent/WO2010047516A2/ko
Publication of WO2010047516A3 publication Critical patent/WO2010047516A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

본 발명은 글루코사민 6 포스페이트 아세틸트랜스퍼라제 활성을 보유하는 N-아세틸 글루코사민을 생산하는 변이 코리네박테리움 속 미생물과 이를 이용한 N-아세틸 글루코사민 또는 글루코사민을 생산하는 방법에 관한 것이다.
PCT/KR2009/006063 2008-10-20 2009-10-20 Ｎ-아세틸 글루코사민 생산능을 가지는 코리네박테리움 속 미생물과 이를 이용한 ｎ-아세틸 글루코사민 또는 글루코사민 생산 방법 WO2010047516A2 (ko)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2011533101A JP5677963B2 (ja) 2008-10-20 2009-10-20 Ｎ−アセチルグルコサミン生産能を有するコリネバクテリウム属微生物とそれを用いたｎ−アセチルグルコサミンまたはグルコサミン生産方法
CN200980145486.5A CN103429731B (zh) 2008-10-20 2009-10-20 具有生产n‑乙酰葡糖胺能力的棒状杆菌属微生物及用其生产n‑乙酰葡糖胺或葡糖胺的方法
EP09822192.2A EP2348101B1 (en) 2008-10-20 2009-10-20 Corynebacterium genus microorganism having ability to produce n-acetyl glucosamine and method for producing n-acetyl glucosamine or glucosamine using same
US13/125,181 US9005957B2 (en) 2008-10-20 2009-10-20 Corynebacterium genus microorganism having ability to produce N-acetyl glucosamine and method for producing N-acetyl glucosamine or glucosamine using the same
ES09822192.2T ES2584531T3 (es) 2008-10-20 2009-10-20 Microorganismo del género Corynebacterium que tiene capacidad para producir N-acetilglucosamina y método para producir N-acetilglucosamina o glucosamina usando el mismo

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20080102633 2008-10-20
KR10-2008-0102633 2008-10-20

Publications (2)

Publication Number Publication Date
WO2010047516A2 WO2010047516A2 (ko) 2010-04-29
WO2010047516A3 true WO2010047516A3 (ko) 2010-09-10

Family

ID=42119826

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/006063 WO2010047516A2 (ko) 2008-10-20 2009-10-20 Ｎ-아세틸 글루코사민 생산능을 가지는 코리네박테리움 속 미생물과 이를 이용한 ｎ-아세틸 글루코사민 또는 글루코사민 생산 방법

Country Status (7)

Country Link
US (1) US9005957B2 (ko)
EP (1) EP2348101B1 (ko)
JP (1) JP5677963B2 (ko)
KR (1) KR101102720B1 (ko)
CN (1) CN103429731B (ko)
ES (1) ES2584531T3 (ko)
WO (1) WO2010047516A2 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8734814B2 (en) * 2012-03-02 2014-05-27 Asis Datta Recombinant microorganisms and uses thereof
CN105695350B (zh) * 2016-03-23 2020-02-07 西藏天虹科技股份有限责任公司 酿酒酵母及酿酒酵母生产氨基葡萄糖的方法
US10724015B2 (en) 2016-05-18 2020-07-28 Korea University Research And Business Foundation Microorganism having improved ability to produce N-acetylglucosamine as a result of modulating glycolytic flux
KR101912359B1 (ko) * 2016-05-18 2018-10-26 고려대학교 산학협력단 해당과정 플럭스 조절에 의해 n-아세틸글루코사민 생성능이 향상된 변이 미생물
KR102254635B1 (ko) * 2021-01-27 2021-05-21 씨제이제일제당 주식회사 신규한 글루코사민-6-포스페이트 디아미나제 변이체 및 이를 이용한 l-글루탐산 생산 방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050003478A1 (en) * 2001-10-26 2005-01-06 Tetsuo Endo Process for producing beta-1, 3-n-acetylglucosamine transferase and n-acetylglucosamine- containing composite saccharide
KR20050053534A (ko) * 2002-07-01 2005-06-08 아르키온 라이프 사이언씨즈 엘엘씨 글루코사민 및 ｎ-아세틸글루코사민의 제조를 위한 물질및 공정
US20060094085A1 (en) * 1997-01-14 2006-05-04 Arkion Life Sciences Llc D/B/A Bio-Technical Resources Process and materials for production of glucosamine
KR20080025355A (ko) * 2006-09-15 2008-03-20 씨제이제일제당 (주) Ｌ－라이신 생산능이 향상된 코리네박테리아 및 그를이용한 ｌ－라이신 생산 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920007401B1 (ko) 1990-06-21 1992-08-31 제일제당 주식회사 다발성 절단부위를 지닌 대장균과 코리네형 세균에서 발현 가능한 신규 셔틀벡터
WO1998030713A1 (en) 1997-01-14 1998-07-16 Bio-Technical Resources Process for production of n-glucosamine
US20020115639A1 (en) 2001-02-16 2002-08-22 Weiyu Fan Glucosamine and method of making glucosamine from microbial blomass
WO2004092391A2 (en) 2003-04-11 2004-10-28 Arkion Life Sciences Llc Metabolic engineering for enhanced production of chitin and chitosan in microorganisms
DE10359594A1 (de) * 2003-12-18 2005-07-28 Basf Ag PEF-TU-Expressionseinheiten
US20070269872A1 (en) * 2006-05-19 2007-11-22 Agribioindustry Inc. Recombinant coryneform bacterium and method for producing diodegradable polyester
JP2008245633A (ja) * 2006-05-19 2008-10-16 Agri Bioindustry:Kk 組換えコリネ型細菌および生分解性ポリエステルの製造方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060094085A1 (en) * 1997-01-14 2006-05-04 Arkion Life Sciences Llc D/B/A Bio-Technical Resources Process and materials for production of glucosamine
US20050003478A1 (en) * 2001-10-26 2005-01-06 Tetsuo Endo Process for producing beta-1, 3-n-acetylglucosamine transferase and n-acetylglucosamine- containing composite saccharide
KR20050053534A (ko) * 2002-07-01 2005-06-08 아르키온 라이프 사이언씨즈 엘엘씨 글루코사민 및 ｎ-아세틸글루코사민의 제조를 위한 물질및 공정
US7332304B2 (en) * 2002-07-01 2008-02-19 Arkion Life Sciences Llc Process and materials for production of glucosamine and N-acetylglucosamine
KR20080025355A (ko) * 2006-09-15 2008-03-20 씨제이제일제당 (주) Ｌ－라이신 생산능이 향상된 코리네박테리아 및 그를이용한 ｌ－라이신 생산 방법

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KAZUHIKO TABATA ET AL.: "Production of UDP-N-acetylglucosamine by coupling metabolically engineered bacteria", BIOTECHNOLOGY LETTERS, vol. 22, 2000, pages 479 - 483, XP008145965 *
See also references of EP2348101A4 *

Also Published As

Publication number Publication date
WO2010047516A2 (ko) 2010-04-29
ES2584531T3 (es) 2016-09-28
US9005957B2 (en) 2015-04-14
CN103429731A (zh) 2013-12-04
CN103429731B (zh) 2017-12-26
KR101102720B1 (ko) 2012-01-05
JP5677963B2 (ja) 2015-02-25
KR20100044129A (ko) 2010-04-29
JP2012505667A (ja) 2012-03-08
EP2348101B1 (en) 2016-05-04
US20110250647A1 (en) 2011-10-13
EP2348101A4 (en) 2013-01-02
EP2348101A2 (en) 2011-07-27

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