WO2010043369A1 - Appareil et procédé de conditionnement d’une poudre - Google Patents

Appareil et procédé de conditionnement d’une poudre Download PDF

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Publication number
WO2010043369A1
WO2010043369A1 PCT/EP2009/007338 EP2009007338W WO2010043369A1 WO 2010043369 A1 WO2010043369 A1 WO 2010043369A1 EP 2009007338 W EP2009007338 W EP 2009007338W WO 2010043369 A1 WO2010043369 A1 WO 2010043369A1
Authority
WO
WIPO (PCT)
Prior art keywords
bag
continuous liner
dcs
glove box
accordance
Prior art date
Application number
PCT/EP2009/007338
Other languages
English (en)
Inventor
Frédéric Jun. DIETRICH
Original Assignee
Fydec Holding Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fydec Holding Sa filed Critical Fydec Holding Sa
Priority to US13/124,264 priority Critical patent/US20110258967A1/en
Priority to EP09744947A priority patent/EP2212205B1/fr
Priority to DE602009000989T priority patent/DE602009000989D1/de
Priority to CN200980140686.1A priority patent/CN102186727B/zh
Priority to AT09744947T priority patent/ATE503688T1/de
Publication of WO2010043369A1 publication Critical patent/WO2010043369A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B69/00—Unpacking of articles or materials, not otherwise provided for
    • B65B69/0075—Emptying systems for flexible intermediate bulk containers [FIBC]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B31/00—Packaging articles or materials under special atmospheric or gaseous conditions; Adding propellants to aerosol containers
    • B65B31/02—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas
    • B65B31/024—Filling, closing, or filling and closing, containers or wrappers in chambers maintained under vacuum or superatmospheric pressure or containing a special atmosphere, e.g. of inert gas specially adapted for wrappers or bags
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B39/00—Nozzles, funnels or guides for introducing articles or materials into containers or wrappers
    • B65B39/06—Nozzles, funnels or guides for introducing articles or materials into containers or wrappers adapted to support containers or wrappers
    • B65B39/08—Nozzles, funnels or guides for introducing articles or materials into containers or wrappers adapted to support containers or wrappers by means of clamps

Definitions

  • the present invention concerns a process as well an apparatus/system for enabling the packaging of a powder, in particular an API, in a contained and GMP manner, without the requirement of a clean room around the filling area. Furthermore, the present invention concerns the use of an apparatus, and process, for pharmaceutical powders and/or for specific pharmaceutical packaging processes.
  • the aim of the invention is to set out a process and an apparatus, with which powder, preferably pharmaceutical powder, can be packaged in at least approximately clean room conditions, without the need to set up the proposed apparatus in a clean room.
  • the invention is based on the concept of using a DCS (drum containment system) glove box, also claimed as an apparatus, for filling a powder with a mean particle diameter in a range between around 10 ⁇ m and around 1000 ⁇ m.
  • DCS drum containment system
  • This is taken to mean an apparatus which has a lower section for holding a drum comprising a first bag, and an upper section, which can be reached into manually with the aid of at least one, preferably with the aid of four, more particularly detachable sealed gloves in order, as will be explained later, to close a second bag and the first bag surrounding the second bag.
  • the powder to be filled is exclusively in contact with the second bag and the first bag forms a second protective covering, where by the first bag and the second bag are surrounded by the apparatus, which than forms an overall protective covering and/or barrier, preferably exposed to an under pressure (negative pressure) and/or an over pressure (positive pressure) .
  • the process and device are particularly suitable for filling powder, more particularly API powder, with a particle size of between 1 and 1000 ⁇ m.
  • the density of the poured powder is between 0.1 and 1 kg/dm 3 .
  • a dosing device forms part of the apparatus, as described, for example in WO 2007/088022 Al by the applicant.
  • the dosing device is preferably arranged in such a way that from it, emerging more particularly as a result of vibration, powder within the DCS glove box can flow into the second bag formed by the hose-like continuous liner.
  • the content of the disclosure of WO 2007/088022 Al should, with regard to possible advantageous embodiments of the dosing device, apply as disclosed as part of the subject matter of the present application.
  • the dosing device operates on a low pressure basis in order to attract powder by way of suction.
  • the unloading of the powder/filling of the second bag preferably takes place by way of vibration, which allows precise dosing of the powder.
  • a dryer is arranged upstream of the dosing device, from which the powder is transferred into a mill, more particularly an online conical mill, which is preferably arranged above the PTS feeder. From the mill the powder is then sucked in by the dosing device.
  • the core of the process is that the powder is filled into a continuous liner, from which the second bag, surrounded by the first bag, is formed by the closing and separation of the remaining continuous liner.
  • the device comprises at least one inlet and/or at least one outlet volatile particle filter, more especially an HEPA particle filter, in order to avoid contamination of the surrounding area and/or the interior of the apparatus .
  • the process in accordance with the invention comprises the following steps:
  • a first bag of flexible packaging material is provided, preferably within a drum, more particularly through insertion of the drum into the lower section of the DCS glove box. It is particularly expedient if doors corresponding to this are provided and the lower section of the DCS glove box is closed on all four sides after closing the doors. Alternatively the lower section is realized without doors, preferably with the front side open.
  • the first bag is attached on a lower outlet, which projects into the lower section of the DCS glove box starting from the upper section. For this the operating gloves of the upper section of the apparatus are used.
  • the continuous liner closed at its lower end, is passed from the upper section of the DCS glove box through the lower outlet thereof into the first bag so that a second bag is provided within the first bag preferably located within the drum.
  • the second bag is then filled with the powder, very particularly preferably via an upper outlet in the upper section of the DCS glove box.
  • Placing the second bag into the first bag preferably takes place manually by way of the gloves, but alternatively can take place automatically through starting the filling procedure.
  • a dosing device as described in said PCT application, is used for filling/dosing.
  • the second bag is closed and separated from the remaining continuous liner, which preferably has already been closed again at its lower end.
  • the first bag which fully surrounds the second bag, is then closed, and preferably closing of the optionally provided drum in the lower section of the DCS glove box takes place before the first bag and the second bag, preferably together with the drum, are removed from the lower section of the DCS glove box, preferably through a, preferably lateral, outlet door which differs from the inlet door.
  • a roller mechanism is provided for facilitated removal of the drum.
  • the invention also relates to an apparatus, i.e. a DCS (drum containment system) glove box, for implementing the process described above.
  • the apparatus is characterised by an upper section, comprising at least one pair of gloves, in which by way of the at least one pair of gloves, which is preferably permanently, but in a replaceably connected in a sealing manner with a housing, intervention can take place, and a lower section, in which a first bag, preferably arranged within a drum, can be accommodated. It is particularly expedient if the apparatus comprises a dosing device as described in the previously cited PCT application.
  • the lower connection to which the first bag can be attached, is the only connection between the upper section and the lower section, with the continuous liner being passable from the upper section through the lower connection into the lower section.
  • the, more particularly, tubular lower connection is within a partition wall which isolates the upper section from the lower section.
  • the DCS glove box prevents contamination of the product and allows the continuous liner to be replaced.
  • the proposed apparatus more particularly at least the upper section, preferably exclusively the upper section of the DCS glove box is, in a further development of the invention, connected to an air circulating system, which is designed so as to guarantee a high rate of air exchange.
  • the air flows through volatile particle filters, more particularly HEPA filters, and particularly preferably at a volumetric flow of 100 NmVhour, which preferably corresponds to a gas exchange rate of 5 to 10 times per minute (depending on the volume of the upper section) .
  • the high rate of gas exchange also prevents powder remaining in and being contaminated in the upper section and thereby guarantees additional product protection.
  • the lower section of the DCS glove box is surrounded by three side walls, more particularly arranged perpendicularly to each other, whereby in at least one side wall, preferably in the front wall, doors are provided.
  • the front side is open permanently.
  • the rear side of a perforated plate, connected to a fan with volatile particle filters, more particularly HEPA filters, is sealed, whereby the fan is arranged and designed so that at least during removal of the drum lid and the connection of the first bag with a lower connection of the DCS glove box, an high pressure predominates.
  • An over pressure is also preferred when dividing/separating the first bag.
  • the air flows at a maximum rate of 0.5 m/sec.
  • the lower section can be realized without means for providing over pressure or under pressure.
  • the system is CIP-capable and can therefore be cleaned by means of a CIP.
  • FIG. 1 to Fig. 23 Process steps of a preferred form of embodiment of a process in accordance with the concept of the invention.
  • Fig. 43 A preferred method (process) for replacing and/or renewing a continuous liner
  • Fig. 44 A variant of embodiment of the apparatus in which both within the continuous liner as well as within the upper and lower section of the DCS glove box a high pressure is produced.
  • Fig. 45 An alternative embodiment variant in which there is a high pressure in the continuous liner and in the lower section of the DCS glove box, and a low pressure in the upper section outside the continuous liner
  • Fig. 46 A table setting out the advantages resulting for a combination of any two barrier features for the form of embodiment in accordance with fig. 44.
  • Fig. 47 A table analogue to fig. 46 for the form of embodiment in accordance with fig. 45.
  • Fig. 48a to 48c Various views and details of a partially incompletely illustrated DCS glove box.
  • Fig. 49 An overall system, comprising a DCS glove box for filling powder.
  • a DCS glove box for filling powder.
  • the same elements and elements with the same function are marked with the same reference symbol.
  • a DCS glove box (hereinafter apparatus 1) is shown. This comprises an upper section 2 and a lower section 3 adjoining it.
  • the lower section 3 is isolated/hermetically sealed off from the upper section 2 by means of an essentially horizontally orientated partition wall.
  • waste container 5 Within the upper section 2 there is a schematically shown waste container 5.
  • gloves 6 operating gloves
  • gloves project into openings provided in the housing and are detachably arranged on the housing 7.
  • a pair of such gloves which are made of flexible material.
  • a lower outlet 11 Passing through the partition wall 4 is a lower outlet 11 (connection) to the outer circumference of which the first bag 9 can be attached.
  • the lower outlet 11 is the only connection between the upper and the lower section 2, 3.
  • an upper outlet 12 which projects into the upper section 2.
  • the powder to be filled can be supplied, preferably by a dosing device, which is not shown, more particularly a PTS feeder.
  • the free end 13 of the upper outlet 12 is surrounded by a continuous liner 14 which is closed at the bottom.
  • a clip 15 or a cable binder is provided to close the continuous liner 14 .
  • a second bag 16 is formed from the continuous liner 14 in a lower section into which the upper outlet 12 projects.
  • the upper outlet 12 is surrounded by a tubular bearing structure 17 on the outer circumference of which the folded continuous liner, which preferably when unfolded is of a length of between 10 and 50 m, preferably around 30 m, is held by means of a, more particularly elastic, clamping ring.
  • the drum 8 is initially inserted from the front side into the lower section 3, which is delimited by three side walls, a base and the partition wall 4.
  • a lid 18 of the initially closed drum 8 is opened within the lower section 3, as indicated in fig. 1, and parked in a corresponding holder, which is not shown.
  • an opening 19 of the first bag 9 is attached to the lower outlet 11, namely in an upper position 20 (cf. fig. 3) by means of an O-ring 21, with which the first bag 9 is attached to an upper circumferential groove 22.
  • the upper position 20 is above the lower position 23 on the lower outlet 11, to which a remainder 24 of an already re-closed first bag is attached by means of an O-ring 25 in a lower circumferential groove 26.
  • the new first bag 9 therefore also surrounds the remainder 24 of the preceding first bag.
  • the drum 8 and with it the first bag 9 are moved by means of the lift mechanism 10 upwards in the plane of the drawing in the direction of the partition wall until an upper circumferential edge 27 of the drum 8 is in contact with the lower side of the partition wall 4.
  • the previously described process is shown in both figs. 5 and 6 jointly.
  • front doors are only closed now so that the lower section 3 is screened off from the outside environment.
  • the lower section is provided without front and/or side doors.
  • Joint consideration of figs. 7 and 8 shows that the remainder 24 of the preceding first bag 9 is removed with the aid of the gloves through the lower outlet 11 upwards into the upper section 2 and then transferred to the waste container 5, so that there is now a direct connection via the lower section 11 between the upper section 2 and the first bag 9.
  • the continuous liner 14 is pressed from outside against the bearing structure 17 by means of an inflatable gasket 28.
  • the upper end 29 of the folded continuous liner 14 is pressed against the bearing structure 17 by means of an 0-ring sealing.
  • gas more particularly air, is released from the inflatable gasket 28 so that the continuous liner 14 can, by means of the gloves within the upper section 2, as shown by the arrow 31, be pulled downwards and inserted into the first bag 9 through the lower outlet 11, which is in axial alignment with the upper connection 12.
  • a second bag 16 is therefore provided within the first bag 9, as can be seen directly in fig. 12.
  • the inflatable gasket is inflated again whereby the inflatable gasket 28 again presses from outside on the continuous liner 14 forcing it against the bearing structure 17, as a result of which contamination of an area above the inflatable gasket 28 can be reliably prevented.
  • the first bag 9 is filled with powder 32.
  • the scales 33 which are connected with a control unit of the dosing device 34 in such a way that the dosing unit 34 feeds powder through the upper connection 12 until the required target weight is achieved.
  • the dosing device 34 is connected to a low pressure line 35 for attracting powder through suction. Via a filter element 36 contamination of the low pressure line 35 is prevented. Preferably the filter element 36 can be cleaned by means of surge pressure.
  • the dosing device 34 comprises a pump chamber 37 which emerges into an oblique pipe 28 on which a vibrator 39 is arranged in order to be able to dose the powder 32 accurately.
  • the dosing device 34 also comprises a closing mechanism 40, preferably designed as a slide, to regulate the filling quantity and/or to stop the filling process, preferably depending on the filling weight measured by the scales.
  • the continuous liner 14 Preferably during the filling procedure there is an over pressure in the lower section of the drum 8, related to atmospheric pressure, and within the upper section 2 outside the continuous liner 14 alternatively a low pressure or high pressure related to atmospheric pressure. Preferably, within the continuous liner 14 there is a certain high pressure, also related to atmospheric pressure, during the filling procedure.
  • a roller mechanism 41 can be seen, which is arranged within and to the side of the lower section 3, the rollers of which may be driven by an electric motor.
  • the roller mechanism 41 is for unloading the first bag 9/the drum 8 from the lower section 3.
  • Fig. 13 also shows that the apparatus 1 has two operating positions 42, 43 on opposite sides. Providing two operating positions 42, 43 facilitates the renewal of the continuous liner 14, which will be explained later. Preferably there is a sliding door 44 before the roller mechanism 41.
  • the continuous liner 14 is closed with a clip 15 at each of two points 45, 46 at distance from each other, as can be seen in figs. 14 and 15, and then cut through in an area between points 45, 46. This therefore results in a closed second bag 16 within the first bag 9, which in turn is arranged in the drum 8.
  • the drum 8 is returned back down into its original position by means of the lift mechanism as shown in fig. 16.
  • the first bag 9 it then closed at two points at a distance from each other, preferably with one clip at each point and then cut through between the two points. This results in a closed second bag 16 within the closed first bag 9.
  • Figs. 18 and 19 show that by cutting through the first bag 9 the remaining section 24 is moved from the upper position 20 to the lower position 23 at the lower connection 11 in order to make space for the next first bag of the next filling procedure.
  • the first bag 9 is closed and the contents are sterile.
  • the first bag 9 is fixed in the upper position 20 by means of an O-ring 21 after the remainder 24 of the preceding first bag has been moved to the lower position 23.
  • the above operating steps are carried out by two persons, located on opposite sides of the apparatus 1, each using a pair of gloves, and preferably also the following step in which the inflatable gasket with its carrier structure 48 is moved upwards and the carrier structure 48 is attached in the lower section of the tubular bearing structure 17.
  • the new continuous liner 14 is closed by means of a clip 15 so that consequently the remainder 49 is within the new continuous liner forming the new, second bag.
  • the remainder 49 of the previous continuous liner together with its CD- ring is removed from the bearing structure 17 and transferred in full into the second bag 16 formed by the continuous liner 14, whereupon the continuous liner is, as shown in figs. 40 and 41, is closed with a clip 15 at two points at a distance from each other and the second bag 16 is separated from the continuous liner 14 in an area between the two points.
  • the second bag 16, incorporating the remainder 49 can now fall into the first bag 9, whereupon, as shown in fig. 42, the first bag 9 is closed, whereby previously the contents of the waste container 5 , i.e. the remainders 24 of the preceding first bags are transferred from the waste container 5 into the first bag.
  • Fig. 44 shows a perspective view of a device 1 with a dosing unit 34.
  • a positive air pressure can be seen within the continuous liner 14 during the filling procedure, a positive air pressure within the upper section 2 and a positive air pressure within the lower section 3.
  • This configuration provides optimum product protection.
  • the table in accordance with fig. 46 summarises the result of the interaction of the various barriers.
  • Fig. 45 shows the identical apparatus as in fig. 44, but the air circulation in the uppers section 2 is such that within the upper section 2 outside the continuous liner 14 a low pressure predominates. In the lower section 3 as well as within the continuous liner 14 there is a slight high pressure. The effects of the interaction of two different barriers are shown in the table in accordance with fig. 47.
  • FIG. 48a to 48c show a possible embodiment variant of an apparatus 1 with a dosing unit 34.
  • the outer walls have not been shown.
  • Lateral openings 51 in the housing of the upper section 2 can be seen, which can be used to operate the apparatus 1 via integral system gloves, which are attached in a detachable sealed manner on the outside of the openings 51.
  • a drum 8 can be seen, which can be moved between a lower and an upper position within the upper section 3 by means of a lift mechanism 10.
  • the lift mechanism 10 stands on a separate weighing mechanism 52 which is connected in a signal-conducting manner to the control system of the dosing unit 34.
  • Fig. 48b shows a section of the dosing unit 34 with a powder supply line 53, pump chamber 37, low pressure connection 35, filter element 36, oblique pipe 38, vibrator 39 and closing mechanism 40 and/or valve.
  • Fig 48c shows the arrangement of a preferably provided roller mechanism 41 for facilitated removal of a drum 8.
  • Fig. 48c shows the position of two volatile particle filters, namely an inlet air volatile particle filter 54 and an outlet air volatile particle filter 55, preferably both HEPA filters, by means of which air circulation in the upper section 2 of the apparatus 1 is brought about.
  • Fig. 49 shows an apparatus 1 (DCS glove box) with an upper section 2 and a lower section 3 in an overall system. It shows the dosing device 35, to which powder is supplied from a mill 56, which is turn is supplied by a dryer 57. To the side there is a sample removing device 58 from which or with which or automatically, product samples can be taken during filling.
  • DCS glove box DCS glove box
  • a sample removing device 58 To the side there is a sample removing device 58 from which or with which or automatically, product samples can be taken during filling.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Basic Packing Technique (AREA)
  • Manipulator (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Supplying Of Containers To The Packaging Station (AREA)

Abstract

L'invention porte sur un procédé qui permet le conditionnement d'une poudre (32), en particulier une poudre de produit pharmaceutique, et qui  consiste : a) à utiliser un premier sac (9) fait d’un matériau d'emballage souple, b) à fixer l'ouverture (19) du premier sac (9) à un orifice de sortie inférieur (11) d'une boîte de protection à gants à DCS (système de confinement à tambour) (1), c) à l'intérieur de la boîte de protection à gants à DSC (1), à tirer un revêtement continu (14) à une extrémité fermée du revêtement (14) et à insérer le revêtement (14) dans le premier sac (9), de façon à fournir ainsi un second sac (16) à l'intérieur du premier sac (9), d) à remplir le second sac (16) avec la poudre (32), en particulier à travers une ouverture supérieure de la boîte de protection à gants à DCS (1), e) à fermer le second sac (16) par le détachement du revêtement continu (14), f), à fermer le premier sac (9) et à retirer les premier et second sacs (9, 16) de la boîte de protection à gants à DSC. L'invention porte en outre sur un appareil de mise en œuvre du procédé.
PCT/EP2009/007338 2008-10-14 2009-10-13 Appareil et procédé de conditionnement d’une poudre WO2010043369A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US13/124,264 US20110258967A1 (en) 2008-10-14 2009-10-13 Product and process for packaging a powder
EP09744947A EP2212205B1 (fr) 2008-10-14 2009-10-13 Appareil et procédé de conditionnement d'une poudre
DE602009000989T DE602009000989D1 (de) 2008-10-14 2009-10-13 Vorrichtung und verfahren zum verpacken eines pulvers
CN200980140686.1A CN102186727B (zh) 2008-10-14 2009-10-13 包装粉末的设备和工艺
AT09744947T ATE503688T1 (de) 2008-10-14 2009-10-13 Vorrichtung und verfahren zum verpacken eines pulvers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08017932 2008-10-14
EP08017932.8 2008-10-14

Publications (1)

Publication Number Publication Date
WO2010043369A1 true WO2010043369A1 (fr) 2010-04-22

Family

ID=41478764

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/007338 WO2010043369A1 (fr) 2008-10-14 2009-10-13 Appareil et procédé de conditionnement d’une poudre

Country Status (6)

Country Link
US (1) US20110258967A1 (fr)
EP (1) EP2212205B1 (fr)
CN (1) CN102186727B (fr)
AT (1) ATE503688T1 (fr)
DE (1) DE602009000989D1 (fr)
WO (1) WO2010043369A1 (fr)

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JP2011240946A (ja) * 2010-05-17 2011-12-01 Shin-Etsu Chemical Co Ltd ペリクルを収納した容器の収納密閉方法
US20140165502A1 (en) * 2011-07-01 2014-06-19 Leung Chi Wah Sealing Apparatus
WO2014009889A1 (fr) * 2012-07-13 2014-01-16 Moretto S.P.A. Dispositif de vidage pour des récipients de stockage de matériaux granulaires ou analogues
DE102012017827B4 (de) * 2012-09-10 2021-07-15 Multivac Sepp Haggenmüller Se & Co. Kg Verfahren zum Betrieb einer Kammermaschine
JP6086830B2 (ja) * 2013-06-28 2017-03-01 澁谷工業株式会社 封じ込めアイソレータを使用した容器開放方法および封じ込めアイソレータ
CN104260912B (zh) * 2014-09-01 2016-09-14 沈阳华盈环保材料有限公司 高效率干粉物料装袋装置
CN104260911A (zh) * 2014-09-01 2015-01-07 沈阳华盈环保材料有限公司 干粉物料装袋装置
CN107310770A (zh) * 2017-07-13 2017-11-03 安徽省华之慧生态农业发展有限公司 一种真空食品包装装置
CA3028781A1 (fr) * 2018-01-08 2019-07-08 Gumpro Drilling Fluids Pvt. Ltd. Appareil et procede d'emballage sous vide d'additifs de fluide de forage solides
EP3718911B1 (fr) * 2019-04-05 2021-10-13 Rubitec AG Dispositif de transvasement permettant de transférer de manière protégée contre la contamination d'un matériau de processus coulant entre un premier et un second récipients
FR3117911B1 (fr) * 2020-12-23 2023-06-30 Thales Sa Dispositif et procédé de manipulation de poudres volatiles
EP4046927A1 (fr) * 2021-02-18 2022-08-24 J. Engelsmann AG Dispositif pour vider un sac de conteneur

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US4308710A (en) 1979-06-06 1982-01-05 E. I. Du Pont De Nemours And Company Process and apparatus for packaging
EP0521252A1 (fr) * 1991-06-25 1993-01-07 Helpmann Holding B.V. Machine de remplissage pour des produits granuleux ou liquides de nature dangereuse
EP0616945A1 (fr) 1993-03-23 1994-09-28 Helpmann Holding B.V. Procédé et dispositif pour le remplissage de produits dangereux dans des récipients
US5810060A (en) 1994-06-02 1998-09-22 Helpman Verfahrenstechnik Gmbh Filling installation for hazardous pourable or fluid substances
EP1619124A1 (fr) 2004-06-01 2006-01-25 Yves Dietrich Dispositif et procédé de remplissage de produits pulvérulents
EP1708941A1 (fr) 2003-12-11 2006-10-11 Hecht Anlagenbau GmbH Procede pour vider et remplir sans contamination des contenants pour matieres en vrac

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Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4308710A (en) 1979-06-06 1982-01-05 E. I. Du Pont De Nemours And Company Process and apparatus for packaging
EP0521252A1 (fr) * 1991-06-25 1993-01-07 Helpmann Holding B.V. Machine de remplissage pour des produits granuleux ou liquides de nature dangereuse
EP0616945A1 (fr) 1993-03-23 1994-09-28 Helpmann Holding B.V. Procédé et dispositif pour le remplissage de produits dangereux dans des récipients
US5810060A (en) 1994-06-02 1998-09-22 Helpman Verfahrenstechnik Gmbh Filling installation for hazardous pourable or fluid substances
EP1708941A1 (fr) 2003-12-11 2006-10-11 Hecht Anlagenbau GmbH Procede pour vider et remplir sans contamination des contenants pour matieres en vrac
EP1619124A1 (fr) 2004-06-01 2006-01-25 Yves Dietrich Dispositif et procédé de remplissage de produits pulvérulents

Also Published As

Publication number Publication date
DE602009000989D1 (de) 2011-05-12
US20110258967A1 (en) 2011-10-27
EP2212205A1 (fr) 2010-08-04
ATE503688T1 (de) 2011-04-15
CN102186727A (zh) 2011-09-14
EP2212205B1 (fr) 2011-03-30
CN102186727B (zh) 2014-03-12

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