WO2009156226A3 - Membrane de soie pour matériau de greffe osseuse et procédé de fabrication de celle-ci - Google Patents

Membrane de soie pour matériau de greffe osseuse et procédé de fabrication de celle-ci Download PDF

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Publication number
WO2009156226A3
WO2009156226A3 PCT/EP2009/055866 EP2009055866W WO2009156226A3 WO 2009156226 A3 WO2009156226 A3 WO 2009156226A3 EP 2009055866 W EP2009055866 W EP 2009055866W WO 2009156226 A3 WO2009156226 A3 WO 2009156226A3
Authority
WO
WIPO (PCT)
Prior art keywords
graft material
bone graft
manufacture
silk membrane
silk
Prior art date
Application number
PCT/EP2009/055866
Other languages
English (en)
Other versions
WO2009156226A2 (fr
Inventor
Michael Rheinnecker
Rolf Zimmat
Original Assignee
Spintec Engineering Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spintec Engineering Gmbh filed Critical Spintec Engineering Gmbh
Publication of WO2009156226A2 publication Critical patent/WO2009156226A2/fr
Publication of WO2009156226A3 publication Critical patent/WO2009156226A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2/2846—Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Transplantation (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La présente invention concerne une membrane de soie (60, 90) ayant deux côtés et revêtue sélectivement sur un des deux côtés avec un matériau de greffe osseuse (10). Le matériau de greffe osseuse (10) est de préférence l’hydroxyapatite ou le phosphate β-tricalcique ou une combinaison de ceux-ci. La membrane de soie (60, 90) a des applications dans la régénération des os (400), en particulier dans la bouche.
PCT/EP2009/055866 2008-06-25 2009-05-14 Membrane de soie pour matériau de greffe osseuse et procédé de fabrication de celle-ci WO2009156226A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0811628.7 2008-06-25
GB0811628A GB2461125A (en) 2008-06-25 2008-06-25 A silk membrane for bone graft material

Publications (2)

Publication Number Publication Date
WO2009156226A2 WO2009156226A2 (fr) 2009-12-30
WO2009156226A3 true WO2009156226A3 (fr) 2010-09-16

Family

ID=39683123

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/055866 WO2009156226A2 (fr) 2008-06-25 2009-05-14 Membrane de soie pour matériau de greffe osseuse et procédé de fabrication de celle-ci

Country Status (2)

Country Link
GB (1) GB2461125A (fr)
WO (1) WO2009156226A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103536962A (zh) * 2012-09-17 2014-01-29 浙江星月生物科技股份有限公司 一种难溶于水的丝素蛋白膜及其制备与应用
CN103536963A (zh) * 2012-09-17 2014-01-29 浙江星月生物科技股份有限公司 一种难溶于水的支架型丝素蛋白膜及其制备与应用

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010522583A (ja) 2007-02-27 2010-07-08 トラスティーズ オブ タフツ カレッジ 組織工学的に作製された絹製臓器
EA019118B1 (ru) 2007-05-29 2014-01-30 Трастиз Оф Тафтс Колледж Способ желатинизации фиброина шелка и регулирования времени желатинизации, способ инкапсуляции по меньшей мере одного компонента в фиброин шелка (варианты)
CA2713251A1 (fr) 2008-02-07 2009-08-13 Trustees Of Tufts College Compositions d'hydroxyapatite et de soie en trois dimensions
US8501172B2 (en) 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
EP2483460B1 (fr) 2009-09-28 2015-09-02 Trustees Of Tufts College Procédé de préparation de fibres de soie électrogélifiées étirées
CA2774643A1 (fr) 2009-09-29 2011-04-07 Trustees Of Tufts College Nanospheres et microspheres de soie et leurs procedes de fabrication
WO2011109691A2 (fr) 2010-03-05 2011-09-09 Trustees Of Tufts College Compositions ionomères à base de soie
EP2611473A4 (fr) 2010-09-01 2014-08-13 Tufts College Biomatériaux à base de fibroïne de soie et de polyéthylène glycol
WO2012054582A2 (fr) 2010-10-19 2012-04-26 Trustees Of Tufts College Micro-aiguilles à base de fibroïne de soie et procédés pour les fabriquer
WO2012145652A1 (fr) 2011-04-20 2012-10-26 Trustees Of Tufts College Revêtements de soie dynamiques pour dispositifs implantables
GB201118000D0 (en) * 2011-10-19 2011-11-30 Orthox Ltd An implantable repair device
CN102512712B (zh) * 2011-12-22 2014-12-10 南京工业大学 具有梯度结构的丝素蛋白多层功能膜及其制备方法
CN103656756B (zh) * 2013-12-13 2014-12-31 苏州大学 一种纳米羟基磷灰石/丝素蛋白复合膜材料及其制备方法
CN103738932B (zh) * 2013-12-13 2016-04-20 苏州大学 一种纳米羟基磷灰石及其制备方法
KR101602797B1 (ko) * 2015-10-21 2016-03-11 대한민국 평면견을 이용한 인공 생체막 및 이의 제조방법
CN108969802A (zh) * 2018-07-19 2018-12-11 浙江大学 一种具有促成骨功能的双诱导羟基磷灰石丝素复合膜制备方法
CN111298198B (zh) * 2019-04-18 2022-03-01 上海交通大学医学院附属第九人民医院 一种双层可吸收仿生屏障膜及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007020449A2 (fr) * 2005-08-17 2007-02-22 Oxford Biomaterials Ltd. Dispositif de reparation de tissu cartilagineux implantable
EP1852470A1 (fr) * 2006-05-03 2007-11-07 Technische Universität München Feuilles multicouches en proteine de soie.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8728463B2 (en) * 2005-03-11 2014-05-20 Wake Forest University Health Science Production of tissue engineered digits and limbs
CA2685225A1 (fr) * 2007-04-25 2008-11-06 Musculoskeletal Transplant Foundation Treillis en materiau biologique renforce pour chirurgie de renforcement

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007020449A2 (fr) * 2005-08-17 2007-02-22 Oxford Biomaterials Ltd. Dispositif de reparation de tissu cartilagineux implantable
EP1852470A1 (fr) * 2006-05-03 2007-11-07 Technische Universität München Feuilles multicouches en proteine de soie.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KINO ET AL: "PREPARATION AND CHARACTERIZATION OF MULTILAYERED HYDROXYAPATITE/SILK FIBROIN FILM", JOURNAL OF BIOSCIENCE AND BIOENGINEERING, vol. 103, no. 6, 28 February 2007 (2007-02-28), pages 514 - 520, XP002589213 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103536962A (zh) * 2012-09-17 2014-01-29 浙江星月生物科技股份有限公司 一种难溶于水的丝素蛋白膜及其制备与应用
CN103536963A (zh) * 2012-09-17 2014-01-29 浙江星月生物科技股份有限公司 一种难溶于水的支架型丝素蛋白膜及其制备与应用
CN103536962B (zh) * 2012-09-17 2016-04-06 浙江星月生物科技股份有限公司 一种难溶于水的丝素蛋白膜及其制备与应用

Also Published As

Publication number Publication date
GB0811628D0 (en) 2008-07-30
WO2009156226A2 (fr) 2009-12-30
GB2461125A (en) 2009-12-30

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