WO2009031318A1 - 鎮痛・抗炎症剤含有外用剤 - Google Patents

鎮痛・抗炎症剤含有外用剤 Download PDF

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Publication number
WO2009031318A1
WO2009031318A1 PCT/JP2008/002456 JP2008002456W WO2009031318A1 WO 2009031318 A1 WO2009031318 A1 WO 2009031318A1 JP 2008002456 W JP2008002456 W JP 2008002456W WO 2009031318 A1 WO2009031318 A1 WO 2009031318A1
Authority
WO
WIPO (PCT)
Prior art keywords
inflammatory agent
preparation
external application
analgesic
steroidal analgesic
Prior art date
Application number
PCT/JP2008/002456
Other languages
English (en)
French (fr)
Inventor
Seiji Miura
Makoto Kanebako
Original Assignee
Kowa Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co., Ltd. filed Critical Kowa Co., Ltd.
Priority to JP2009531137A priority Critical patent/JPWO2009031318A1/ja
Publication of WO2009031318A1 publication Critical patent/WO2009031318A1/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

　次の成分(A)及び(B)を含有する外用剤。 　(A) 非ステロイド性鎮痛・抗炎症剤 　(B) ポリオキシアルキレンアルキルエーテル及び／又はポリオキシアルキレンアルケニルエーテル 　本発明の外用剤は、非ステロイド性鎮痛・抗炎症剤の皮膚透過性が改善され、これにより低濃度で効果を発現することができ、また美観にも優れるものである。
PCT/JP2008/002456 2007-09-05 2008-09-05 鎮痛・抗炎症剤含有外用剤 WO2009031318A1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009531137A JPWO2009031318A1 (ja) 2007-09-05 2008-09-05 鎮痛・抗炎症剤含有外用剤

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2007-230108 2007-09-05
JP2007230108 2007-09-05
JP2008-083107 2008-03-27
JP2008083108 2008-03-27
JP2008083107 2008-03-27
JP2008-083108 2008-03-27

Publications (1)

Publication Number Publication Date
WO2009031318A1 true WO2009031318A1 (ja) 2009-03-12

Family

ID=40428643

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/002456 WO2009031318A1 (ja) 2007-09-05 2008-09-05 鎮痛・抗炎症剤含有外用剤

Country Status (2)

Country Link
JP (1) JPWO2009031318A1 (ja)
WO (1) WO2009031318A1 (ja)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011074032A (ja) * 2009-09-30 2011-04-14 Kobayashi Pharmaceutical Co Ltd 外用医薬組成物
WO2012102242A1 (ja) * 2011-01-24 2012-08-02 ニプロパッチ株式会社 含水系貼付剤
WO2014159812A1 (en) * 2013-03-14 2014-10-02 Avery Dennison Corporation Stabilization of essential oils within a hydrocolloid adhesive
JP2014196372A (ja) * 2014-07-23 2014-10-16 小林製薬株式会社 外用医薬組成物
US9775908B2 (en) 2007-07-10 2017-10-03 Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag Pharmaceutical preparations containing highly volatile silicones
JP2018503689A (ja) * 2015-01-27 2018-02-08 フローレンゲイル・エル・エル・シー 治癒性局所用組成物
US10045935B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
JP2018184479A (ja) * 2012-06-22 2018-11-22 興和株式会社 ロキソプロフェンを含有する医薬組成物３
US11154535B2 (en) 2012-07-31 2021-10-26 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
BE1029346B1 (de) * 2021-09-16 2022-11-25 Jiangxi Wenxu Biological Tech Co Ltd Arthritis-tinktur und herstellungsverfahren

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5879918A (ja) * 1981-11-06 1983-05-13 Nitto Electric Ind Co Ltd 消炎鎮痛貼付剤
JPS58103311A (ja) * 1981-09-01 1983-06-20 Hisamitsu Pharmaceut Co Inc 消炎鎮痛クリーム剤
JPS58189115A (ja) * 1982-04-30 1983-11-04 Kowa Co 外用剤
JPS6456622A (en) * 1987-08-28 1989-03-03 Ss Pharmaceutical Co Percutaneous absorbefacient base composition
JPH10218793A (ja) * 1997-02-03 1998-08-18 Nichiban Co Ltd 経皮吸収型消炎鎮痛用テープ剤及びその製造方法
JP2000143540A (ja) * 1998-11-06 2000-05-23 Bristol Myers Squibb Co 非ステロイド系消炎鎮痛薬含有外用剤
WO2000051575A1 (en) * 1999-03-01 2000-09-08 Amarin Technologies S.A. Transdermal device comprising non-steroidal anti-inflammatory drugs incorporated in acrylic adhesive polymer matrix
JP2004083462A (ja) * 2002-08-26 2004-03-18 Yuutoku Yakuhin Kogyo Kk 外用貼付剤及び外用貼付剤中の薬物のエステル化抑制方法

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58103311A (ja) * 1981-09-01 1983-06-20 Hisamitsu Pharmaceut Co Inc 消炎鎮痛クリーム剤
JPS5879918A (ja) * 1981-11-06 1983-05-13 Nitto Electric Ind Co Ltd 消炎鎮痛貼付剤
JPS58189115A (ja) * 1982-04-30 1983-11-04 Kowa Co 外用剤
JPS6456622A (en) * 1987-08-28 1989-03-03 Ss Pharmaceutical Co Percutaneous absorbefacient base composition
JPH10218793A (ja) * 1997-02-03 1998-08-18 Nichiban Co Ltd 経皮吸収型消炎鎮痛用テープ剤及びその製造方法
JP2000143540A (ja) * 1998-11-06 2000-05-23 Bristol Myers Squibb Co 非ステロイド系消炎鎮痛薬含有外用剤
WO2000051575A1 (en) * 1999-03-01 2000-09-08 Amarin Technologies S.A. Transdermal device comprising non-steroidal anti-inflammatory drugs incorporated in acrylic adhesive polymer matrix
JP2004083462A (ja) * 2002-08-26 2004-03-18 Yuutoku Yakuhin Kogyo Kk 外用貼付剤及び外用貼付剤中の薬物のエステル化抑制方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"The merck index, 13th edition "Amfenac"", 2001, pages: 70 *

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9775908B2 (en) 2007-07-10 2017-10-03 Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag Pharmaceutical preparations containing highly volatile silicones
JP2011074032A (ja) * 2009-09-30 2011-04-14 Kobayashi Pharmaceutical Co Ltd 外用医薬組成物
JP5781097B2 (ja) * 2011-01-24 2015-09-16 ニプロパッチ株式会社 含水系貼付剤
JP2014156498A (ja) * 2011-01-24 2014-08-28 Nipro Patch Co Ltd 含水系貼付剤
JP2014156497A (ja) * 2011-01-24 2014-08-28 Nipro Patch Co Ltd 含水系貼付剤
CN103501779A (zh) * 2011-01-24 2014-01-08 尼普洛外用药品株式会社 含水性贴附剂
JP2014156499A (ja) * 2011-01-24 2014-08-28 Nipro Patch Co Ltd 含水系貼付剤
CN103501779B (zh) * 2011-01-24 2016-08-10 尼普洛外用药品株式会社 含水性贴附剂
WO2012102242A1 (ja) * 2011-01-24 2012-08-02 ニプロパッチ株式会社 含水系貼付剤
JP2018184479A (ja) * 2012-06-22 2018-11-22 興和株式会社 ロキソプロフェンを含有する医薬組成物３
US10045935B2 (en) 2012-07-31 2018-08-14 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
US11154535B2 (en) 2012-07-31 2021-10-26 Egis Pharmaceuticals Plc Transdermal formulation containing COX inhibitors
CN105163725A (zh) * 2013-03-14 2015-12-16 艾利丹尼森公司 胶体粘合剂内精油的稳定化
WO2014159812A1 (en) * 2013-03-14 2014-10-02 Avery Dennison Corporation Stabilization of essential oils within a hydrocolloid adhesive
JP2014196372A (ja) * 2014-07-23 2014-10-16 小林製薬株式会社 外用医薬組成物
JP2018503689A (ja) * 2015-01-27 2018-02-08 フローレンゲイル・エル・エル・シー 治癒性局所用組成物
BE1029346B1 (de) * 2021-09-16 2022-11-25 Jiangxi Wenxu Biological Tech Co Ltd Arthritis-tinktur und herstellungsverfahren

Also Published As

Publication number Publication date
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