WO2009016718A1 - 診断薬及びそれを用いた診断方法 - Google Patents

診断薬及びそれを用いた診断方法 Download PDF

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Publication number
WO2009016718A1
WO2009016718A1 PCT/JP2007/064894 JP2007064894W WO2009016718A1 WO 2009016718 A1 WO2009016718 A1 WO 2009016718A1 JP 2007064894 W JP2007064894 W JP 2007064894W WO 2009016718 A1 WO2009016718 A1 WO 2009016718A1
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WO
WIPO (PCT)
Prior art keywords
diagnostic
diagnostic agent
antibody
agent
same
Prior art date
Application number
PCT/JP2007/064894
Other languages
English (en)
French (fr)
Inventor
Shinichiro Isobe
Original Assignee
Shinichiro Isobe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40303963&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2009016718(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Shinichiro Isobe filed Critical Shinichiro Isobe
Priority to JP2009525210A priority Critical patent/JP5189096B2/ja
Priority to PCT/JP2007/064894 priority patent/WO2009016718A1/ja
Publication of WO2009016718A1 publication Critical patent/WO2009016718A1/ja

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0058—Antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

　抗体に対する標識率が高く、蛍光強度の大きい蛍光色素を用いた診断薬を提供する。本発明の診断薬は、蛍光色素に有機EL色素から成る発色部と、抗体と結合する結合部とを有するものを用いる。従来に比べ抗体に対する標識率を向上させるとともに、固体状態でも高い蛍光強度により抗原をより高感度で検出することができる。
PCT/JP2007/064894 2007-07-30 2007-07-30 診断薬及びそれを用いた診断方法 WO2009016718A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2009525210A JP5189096B2 (ja) 2007-07-30 2007-07-30 診断薬及びそれを用いた測定方法
PCT/JP2007/064894 WO2009016718A1 (ja) 2007-07-30 2007-07-30 診断薬及びそれを用いた診断方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2007/064894 WO2009016718A1 (ja) 2007-07-30 2007-07-30 診断薬及びそれを用いた診断方法

Publications (1)

Publication Number Publication Date
WO2009016718A1 true WO2009016718A1 (ja) 2009-02-05

Family

ID=40303963

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/064894 WO2009016718A1 (ja) 2007-07-30 2007-07-30 診断薬及びそれを用いた診断方法

Country Status (2)

Country Link
JP (1) JP5189096B2 (ja)
WO (1) WO2009016718A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104697936A (zh) * 2015-02-11 2015-06-10 深圳市前海安测信息技术有限公司 用于检测生物标志物浓度的生物传感系统及其检测方法
CN104710978A (zh) * 2015-02-11 2015-06-17 深圳市前海安测信息技术有限公司 有机电致发光材料及其制备方法
WO2016127460A1 (zh) * 2015-02-11 2016-08-18 深圳市前海安测信息技术有限公司 有机电致发光元件
JP2019048908A (ja) * 2017-09-07 2019-03-28 信一郎 礒部 蛍光色素

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007013601A1 (ja) * 2005-07-28 2007-02-01 Shinichiro Isobe 生体分子用標識色素及び標識キット並びに生体分子の検出方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007013601A1 (ja) * 2005-07-28 2007-02-01 Shinichiro Isobe 生体分子用標識色素及び標識キット並びに生体分子の検出方法

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104697936A (zh) * 2015-02-11 2015-06-10 深圳市前海安测信息技术有限公司 用于检测生物标志物浓度的生物传感系统及其检测方法
CN104710978A (zh) * 2015-02-11 2015-06-17 深圳市前海安测信息技术有限公司 有机电致发光材料及其制备方法
WO2016127460A1 (zh) * 2015-02-11 2016-08-18 深圳市前海安测信息技术有限公司 有机电致发光元件
JP2019048908A (ja) * 2017-09-07 2019-03-28 信一郎 礒部 蛍光色素
JP7014549B2 (ja) 2017-09-07 2022-02-01 信一郎 礒部 蛍光色素

Also Published As

Publication number Publication date
JPWO2009016718A1 (ja) 2010-10-07
JP5189096B2 (ja) 2013-04-24

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WO2009016718A1 (ja) 診断薬及びそれを用いた診断方法

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