WO2009013846A1 - 前立腺肥大に伴う下部尿路症状の改善用医薬組成物 - Google Patents

前立腺肥大に伴う下部尿路症状の改善用医薬組成物 Download PDF

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Publication number
WO2009013846A1
WO2009013846A1 PCT/JP2007/074717 JP2007074717W WO2009013846A1 WO 2009013846 A1 WO2009013846 A1 WO 2009013846A1 JP 2007074717 W JP2007074717 W JP 2007074717W WO 2009013846 A1 WO2009013846 A1 WO 2009013846A1
Authority
WO
WIPO (PCT)
Prior art keywords
prostatomegaly
pharmaceutical composition
urinary tract
symptom associated
lower urinary
Prior art date
Application number
PCT/JP2007/074717
Other languages
English (en)
French (fr)
Inventor
Hidehiro Kakizaki
Masaki Yoshida
Original Assignee
Astellas Pharma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40281108&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2009013846(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astellas Pharma Inc. filed Critical Astellas Pharma Inc.
Priority to CN200780053847A priority Critical patent/CN101754760A/zh
Priority to CA2697137A priority patent/CA2697137A1/en
Priority to EP07851069A priority patent/EP2172201A4/en
Priority to JP2009524370A priority patent/JPWO2009013846A1/ja
Publication of WO2009013846A1 publication Critical patent/WO2009013846A1/ja
Priority to US12/688,426 priority patent/US20100331361A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

 (R)-5-(2-{[2-(2-エトキシフェノキシ)エチル]アミノ}プロピル)-2-メトキシベンゼン-1-スルホンアミド(タムスロシン)又はその製薬学的に許容される塩、及び、(1S)-1-フェニル-1,2,3,4-テトラヒドロイソキノリン-2-カルボン酸 (3R)-キヌクリジン-3-イルエステル(ソリフェナシン)又はその製薬学的に許容される塩を有効成分とする医薬組成物、特に前立腺肥大に伴う下部尿路症状の改善用医薬組成物を提供する。また、前立腺肥大に伴う下部尿路症状の改善のためのタムスロシンまたはその製薬学的に許容される塩、及び、ソリフェナシンまたはその製薬学的に許容される塩の併用、及び併用療法を提供する。
PCT/JP2007/074717 2007-07-20 2007-12-21 前立腺肥大に伴う下部尿路症状の改善用医薬組成物 WO2009013846A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN200780053847A CN101754760A (zh) 2007-07-20 2007-12-21 用以改善伴随着前列腺肥大的下尿路症状的药物组合物
CA2697137A CA2697137A1 (en) 2007-07-20 2007-12-21 Pharmaceutical composition for amelioration of lower urinary tract symptoms associated with prostatomegaly
EP07851069A EP2172201A4 (en) 2007-07-20 2007-12-21 PHARMACEUTICAL COMPOSITION FOR THE REDUCTION OF LOWER HARNESS SYMPTOMS RELATED TO PROSTATE GAL
JP2009524370A JPWO2009013846A1 (ja) 2007-07-20 2007-12-21 前立腺肥大に伴う下部尿路症状の改善用医薬組成物
US12/688,426 US20100331361A1 (en) 2007-07-20 2010-01-15 Pharmaceutical composition containing alpha-adrenergic receptor antagonist and an anti-muscarinic agent and method of improving lower urinary tract symptoms associated with prostatic hypertrophy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92999607P 2007-07-20 2007-07-20
US60/929996 2007-07-20

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/688,426 Continuation-In-Part US20100331361A1 (en) 2007-07-20 2010-01-15 Pharmaceutical composition containing alpha-adrenergic receptor antagonist and an anti-muscarinic agent and method of improving lower urinary tract symptoms associated with prostatic hypertrophy

Publications (1)

Publication Number Publication Date
WO2009013846A1 true WO2009013846A1 (ja) 2009-01-29

Family

ID=40281108

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/074717 WO2009013846A1 (ja) 2007-07-20 2007-12-21 前立腺肥大に伴う下部尿路症状の改善用医薬組成物

Country Status (8)

Country Link
US (1) US20100331361A1 (ja)
EP (1) EP2172201A4 (ja)
JP (1) JPWO2009013846A1 (ja)
KR (1) KR20100040294A (ja)
CN (1) CN101754760A (ja)
CA (1) CA2697137A1 (ja)
TW (1) TW200904424A (ja)
WO (1) WO2009013846A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010090172A1 (ja) 2009-02-04 2010-08-12 アステラス製薬株式会社 経口投与用医薬組成物
JP2016508958A (ja) * 2012-10-15 2016-03-24 ケミン、インダストリーズ、インコーポレーテッドKemin Industries, Inc. 健康を促進するための緑茶抽出物と紅茶抽出物との混合物

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102743757A (zh) * 2012-07-09 2012-10-24 张家华 治疗膀胱流出道梗阻所致膀胱活动过度的药物
CN106562968B (zh) * 2015-10-13 2019-08-13 南京华威医药科技集团有限公司 包含盐酸坦洛辛和琥珀酸索利那新的药物组合物

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703063A (en) 1980-02-08 1987-10-27 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl substituted phenethylamine derivatives and process of producing them
WO1996020194A1 (fr) 1994-12-28 1996-07-04 Yamanouchi Pharmaceutical Co., Ltd. Nouveaux derives de quinuclidine et composition pharmaceutique les contenant
JP2001114679A (ja) * 1999-08-09 2001-04-24 Yamanouchi Pharmaceut Co Ltd 下部尿路症治療剤
WO2003103659A1 (ja) * 2002-06-07 2003-12-18 山之内製薬株式会社 過活動膀胱治療剤
WO2006090759A1 (ja) * 2005-02-25 2006-08-31 Astellas Pharma Inc. ソリフェナシン含有医薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1192769C (zh) * 1999-08-09 2005-03-16 山之内制药株式会社 下部尿路症治疗用医药组合物
IL141235A (en) * 2000-02-09 2012-04-30 Novartis Int Pharm Ltd Combined use of an alpha-adrenoceptor antagonist and a muscarinic antagonist in the preparation of a drug for the treatment of non-malignant prostatic hyperplasia
PT1806136E (pt) * 2004-10-06 2012-03-08 Kissei Pharmaceutical Composição medicamentosa para a prevenção da transição para o tratamento operatório da hipertrofia prostática
EP2181707A1 (en) * 2008-11-04 2010-05-05 Astellas Ireland Co., Ltd. Combined use of an alpha-adrenergic receptor antagonist and an anti-muscarinic agent

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703063A (en) 1980-02-08 1987-10-27 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl substituted phenethylamine derivatives and process of producing them
WO1996020194A1 (fr) 1994-12-28 1996-07-04 Yamanouchi Pharmaceutical Co., Ltd. Nouveaux derives de quinuclidine et composition pharmaceutique les contenant
JP2001114679A (ja) * 1999-08-09 2001-04-24 Yamanouchi Pharmaceut Co Ltd 下部尿路症治療剤
WO2003103659A1 (ja) * 2002-06-07 2003-12-18 山之内製薬株式会社 過活動膀胱治療剤
WO2006090759A1 (ja) * 2005-02-25 2006-08-31 Astellas Pharma Inc. ソリフェナシン含有医薬

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
FOLIA PHARMACOLOGICA JAPONICA, vol. 12, 2003, pages 331
See also references of EP2172201A4 *
THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, vol. 296, no. 19, 2006, pages 2319
THE JOURNAL OF UROLOGY, vol. 174, 2005, pages 1334

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010090172A1 (ja) 2009-02-04 2010-08-12 アステラス製薬株式会社 経口投与用医薬組成物
EP2394648A4 (en) * 2009-02-04 2012-08-29 Astellas Pharma Inc PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
JP5553026B2 (ja) * 2009-02-04 2014-07-16 アステラス製薬株式会社 経口投与用医薬組成物
US9198904B2 (en) 2009-02-04 2015-12-01 Astellas Pharma Inc. Pharmaceutical composition for oral administration
EP2394648B1 (en) 2009-02-04 2016-08-31 Astellas Pharma Inc. Pharmaceutical composition for oral administration
JP2016508958A (ja) * 2012-10-15 2016-03-24 ケミン、インダストリーズ、インコーポレーテッドKemin Industries, Inc. 健康を促進するための緑茶抽出物と紅茶抽出物との混合物

Also Published As

Publication number Publication date
KR20100040294A (ko) 2010-04-19
CA2697137A1 (en) 2009-01-29
EP2172201A4 (en) 2011-07-06
TW200904424A (en) 2009-02-01
JPWO2009013846A1 (ja) 2010-10-07
EP2172201A1 (en) 2010-04-07
US20100331361A1 (en) 2010-12-30
CN101754760A (zh) 2010-06-23

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