WO2008120562A1 - 帯状疱疹後神経痛治療用錠剤および帯状疱疹後神経痛の治療方法 - Google Patents

帯状疱疹後神経痛治療用錠剤および帯状疱疹後神経痛の治療方法 Download PDF

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Publication number
WO2008120562A1
WO2008120562A1 PCT/JP2008/054795 JP2008054795W WO2008120562A1 WO 2008120562 A1 WO2008120562 A1 WO 2008120562A1 JP 2008054795 W JP2008054795 W JP 2008054795W WO 2008120562 A1 WO2008120562 A1 WO 2008120562A1
Authority
WO
WIPO (PCT)
Prior art keywords
postherpetic neuralgia
treating
tablet
therapeutic tablet
therapeutic
Prior art date
Application number
PCT/JP2008/054795
Other languages
English (en)
French (fr)
Inventor
Takuji Fukuno
Hiroshi Tachimori
Fuminori Mukunoki
Tadayo Miyasaka
Hiromasa Araki
Shuichi Tanaka
Shingo Doi
Shoichi Kawazoe
Original Assignee
Toyo Boseki Kabushiki Kaisha
Fuso Pharmaceutical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Boseki Kabushiki Kaisha, Fuso Pharmaceutical Industries, Ltd. filed Critical Toyo Boseki Kabushiki Kaisha
Priority to EP08722191A priority Critical patent/EP2130539A4/en
Priority to JP2009507450A priority patent/JPWO2008120562A1/ja
Priority to US12/527,124 priority patent/US20110008431A1/en
Publication of WO2008120562A1 publication Critical patent/WO2008120562A1/ja
Priority to IL200406A priority patent/IL200406A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

　本発明は、帯状疱疹後神経痛を治療するための錠剤、および当該錠剤を用いる帯状疱疹後神経痛の治療方法を提供することを目的とする。本発明の帯状疱疹後神経痛治療用錠剤は、塩酸ブプレノルフィンを含有し、速放性層と徐放性層からなる二層構造を有し、且つ口腔粘膜に貼り付けるものであることを特徴とする。
PCT/JP2008/054795 2007-04-02 2008-03-14 帯状疱疹後神経痛治療用錠剤および帯状疱疹後神経痛の治療方法 WO2008120562A1 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP08722191A EP2130539A4 (en) 2007-04-02 2008-03-14 THERAPEUTIC TABLET FOR POST-HERPETIC NEURALITY AND METHOD FOR TREATMENT OF POST-HERPETIC NEURALITY
JP2009507450A JPWO2008120562A1 (ja) 2007-04-02 2008-03-14 帯状疱疹後神経痛治療用錠剤および帯状疱疹後神経痛の治療方法
US12/527,124 US20110008431A1 (en) 2007-04-02 2008-03-14 Therapeutic tablet for postherpetic neuralgia and method of treating postherpetic neuralgia
IL200406A IL200406A0 (en) 2007-04-02 2009-08-13 Therapeutic tablet for postherpetic neuralgia

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007096812 2007-04-02
JP2007-096812 2007-04-02

Publications (1)

Publication Number Publication Date
WO2008120562A1 true WO2008120562A1 (ja) 2008-10-09

Family

ID=39808145

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/054795 WO2008120562A1 (ja) 2007-04-02 2008-03-14 帯状疱疹後神経痛治療用錠剤および帯状疱疹後神経痛の治療方法

Country Status (7)

Country Link
US (1) US20110008431A1 (ja)
EP (1) EP2130539A4 (ja)
JP (1) JPWO2008120562A1 (ja)
KR (1) KR20090125748A (ja)
CN (1) CN101631550A (ja)
IL (1) IL200406A0 (ja)
WO (1) WO2008120562A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2008111674A1 (ja) * 2007-03-15 2010-06-24 東洋紡績株式会社 口腔粘膜貼付ブプレノルフィン製剤の製造方法
WO2013080271A1 (ja) * 2011-11-28 2013-06-06 東洋紡株式会社 鎮痛剤
KR20160095358A (ko) 2015-02-03 2016-08-11 고려대학교 산학협력단 우고닌 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 헤르페스 바이러스 감염 질환의 예방 또는 치료용 약학적 조성물
WO2017146104A1 (ja) * 2016-02-25 2017-08-31 久光製薬株式会社 口腔内貼付剤

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210100964A (ko) 2020-02-07 2021-08-18 김휘영 영장류 대상포진치료장치 및 그 장치의 구동방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08291070A (ja) 1995-04-21 1996-11-05 Toyobo Co Ltd 口腔粘膜貼付ブプレノルフィン製剤
WO2004091593A2 (en) * 2003-04-14 2004-10-28 Pain Therapeutics, Inc. Methods for the treatment of pain comprising opioid antagonists
JP2005533046A (ja) 2002-06-10 2005-11-04 エムエル・ラボラトリーズ・パブリック・リミテッド・カンパニー 鎮痛薬の作用を増強するためにオピオイド鎮痛薬と併用するデバゼピドの使用
WO2006049312A1 (ja) * 2004-11-05 2006-05-11 Japan Science And Technology Agency 神経因性疼痛治療剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968547A (en) * 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
US6210699B1 (en) * 1999-04-01 2001-04-03 Watson Pharmaceuticals, Inc. Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity
AUPR731901A0 (en) * 2001-08-28 2001-09-20 Goodchild, Colin Stanley Method of treatment
US7666876B2 (en) * 2002-03-19 2010-02-23 Vernalis (R&D) Limited Buprenorphine formulations for intranasal delivery
US8252328B2 (en) * 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US20100098757A1 (en) * 2007-03-15 2010-04-22 Toyo Boseki Kabushiki Kaisha Process for production of buprenorphine pharmaceutical preparation to be applied to mouth mucosa

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08291070A (ja) 1995-04-21 1996-11-05 Toyobo Co Ltd 口腔粘膜貼付ブプレノルフィン製剤
JP2005533046A (ja) 2002-06-10 2005-11-04 エムエル・ラボラトリーズ・パブリック・リミテッド・カンパニー 鎮痛薬の作用を増強するためにオピオイド鎮痛薬と併用するデバゼピドの使用
WO2004091593A2 (en) * 2003-04-14 2004-10-28 Pain Therapeutics, Inc. Methods for the treatment of pain comprising opioid antagonists
WO2006049312A1 (ja) * 2004-11-05 2006-05-11 Japan Science And Technology Agency 神経因性疼痛治療剤
JP2006131545A (ja) 2004-11-05 2006-05-25 Japan Science & Technology Agency 神経因性疼痛治療剤

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Title
ARITA E. ET AL.: "Buprenorphine ni yoru Chiryo", JOURNAL OF PAIN AND CLINICAL MEDICINE, vol. 3, no. 2, 2003, pages 192 - 198, XP008142118 *
C. PETER N. WATSON ET AL., AMERICAN ACADEMY OF NEUROLOGY, vol. 50, 1998, pages 1837 - 1841
CHRISTO P.J. ET AL.: "Post-Hepatic Neuralgia in Older Adults", DRUGS AGING, vol. 24, no. 1, 21 February 2007 (2007-02-21), pages 1 - 19, XP008115594 *
HIDEO YAMAMURA ET AL., IGAKU NO AYUMI, vol. 147, no. 7, 1988, pages 651 - 664
KATSUO TOIDE, JOURNAL OF THE JAPANESE PHARMACOLOGICAL SOCIETY, vol. 128, 2006, pages 321 - 325
MICHAEL C. ROWBOTHAM ET AL., NEUROLOGY, vol. 41, 1991, pages 1024 - 1028
MICHIO HASHIKABE ET AL., NISHI NICHI HIFU, vol. 65, no. 1, 2003, pages 65 - 69
ROBERT H. DWORKIN ET AL., ARCHIVES OF NEUROLOGY, vol. 60, 2003, pages 1524 - 1534
ZENZ M. ET AL.: "Long-Term Oral Opioid Therapy in Patients with Chronic Nonmalignant Pain", JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, vol. 7, no. 2, 1992, pages 69 - 77, XP023115646 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2008111674A1 (ja) * 2007-03-15 2010-06-24 東洋紡績株式会社 口腔粘膜貼付ブプレノルフィン製剤の製造方法
WO2013080271A1 (ja) * 2011-11-28 2013-06-06 東洋紡株式会社 鎮痛剤
KR20160095358A (ko) 2015-02-03 2016-08-11 고려대학교 산학협력단 우고닌 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 헤르페스 바이러스 감염 질환의 예방 또는 치료용 약학적 조성물
WO2017146104A1 (ja) * 2016-02-25 2017-08-31 久光製薬株式会社 口腔内貼付剤
JPWO2017146104A1 (ja) * 2016-02-25 2018-10-04 久光製薬株式会社 口腔内貼付剤

Also Published As

Publication number Publication date
US20110008431A1 (en) 2011-01-13
JPWO2008120562A1 (ja) 2010-07-15
EP2130539A4 (en) 2010-05-19
IL200406A0 (en) 2010-04-29
EP2130539A1 (en) 2009-12-09
CN101631550A (zh) 2010-01-20
KR20090125748A (ko) 2009-12-07

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