WO2008117707A1 - オルメサルタンメドキソミルの粉砕結晶 - Google Patents
オルメサルタンメドキソミルの粉砕結晶 Download PDFInfo
- Publication number
- WO2008117707A1 WO2008117707A1 PCT/JP2008/055036 JP2008055036W WO2008117707A1 WO 2008117707 A1 WO2008117707 A1 WO 2008117707A1 JP 2008055036 W JP2008055036 W JP 2008055036W WO 2008117707 A1 WO2008117707 A1 WO 2008117707A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- olmesartan medoxomil
- ground crystal
- crystal
- ground
- particle diameter
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002681591A CA2681591A1 (en) | 2007-03-23 | 2008-03-19 | Pulverized crystals of olmesartan medoxomil |
EP08722426A EP2141160A4 (en) | 2007-03-23 | 2008-03-19 | GROUND CRYSTAL OLMESARTAN MEDOXOMIL |
BRPI0809161-7A BRPI0809161A2 (pt) | 2007-03-23 | 2008-03-19 | Olmesartan medoxomil, processos para a produção do mesmo, e, para a produção de um medicamento compreendendo olmesartan medoxomil, medicamento, e, uso de olmesartan medoxomil |
JP2009506296A JPWO2008117707A1 (ja) | 2007-03-23 | 2008-03-19 | オルメサルタンメドキソミルの粉砕結晶 |
CN200880017194A CN101679390A (zh) | 2007-03-23 | 2008-03-19 | 奥美沙坦酯的粉碎结晶 |
US12/584,960 US20100062070A1 (en) | 2007-03-23 | 2009-09-15 | Pulverzed crystals of olmesartan medoxomil |
IL201007A IL201007A0 (en) | 2007-03-23 | 2009-09-17 | Pulverized crystal of olmesartan medoxomil |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007-075701 | 2007-03-23 | ||
JP2007075701 | 2007-03-23 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/584,960 Continuation US20100062070A1 (en) | 2007-03-23 | 2009-09-15 | Pulverzed crystals of olmesartan medoxomil |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008117707A1 true WO2008117707A1 (ja) | 2008-10-02 |
Family
ID=39788443
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/055036 WO2008117707A1 (ja) | 2007-03-23 | 2008-03-19 | オルメサルタンメドキソミルの粉砕結晶 |
Country Status (10)
Country | Link |
---|---|
US (1) | US20100062070A1 (ja) |
EP (1) | EP2141160A4 (ja) |
JP (1) | JPWO2008117707A1 (ja) |
KR (1) | KR20090122455A (ja) |
CN (1) | CN101679390A (ja) |
BR (1) | BRPI0809161A2 (ja) |
CA (1) | CA2681591A1 (ja) |
IL (1) | IL201007A0 (ja) |
TW (1) | TW200840565A (ja) |
WO (1) | WO2008117707A1 (ja) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011045760A2 (en) | 2009-10-13 | 2011-04-21 | Ranbaxy Laboratories Limited | Micronized olmesartan medoxomil compositions |
WO2010146408A3 (en) * | 2009-06-19 | 2011-08-11 | Nanoform Cardiovascular Therapeutics Ltd | Nanoparticulate olmesartan medoxomil compositions, process for the preparation thereof and pharmaceutical compositions containing them |
JP2016044170A (ja) * | 2014-08-27 | 2016-04-04 | 日本ケミファ株式会社 | オルメサルタンのプロドラッグ製剤 |
US20220133720A1 (en) * | 2019-02-26 | 2022-05-05 | Daewoong Pharmaceutical Co., Ltd. | Pharmaceutical composition of single dosage form for treating or preventing hypertension and hyperlipidemia |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014002011A1 (en) * | 2012-06-26 | 2014-01-03 | Micro Labs Limited | Micronized particles of olmesartan medoxomil and pharmaceutical composition thereof |
WO2014030082A1 (en) | 2012-08-22 | 2014-02-27 | Lupin Limited | Novel method to obtain olmesartan medoxomil with reduced particle size |
CN104398483B (zh) * | 2014-11-05 | 2018-01-26 | 上海医药集团青岛国风药业股份有限公司 | 一种奥美沙坦酯片及其制备工艺 |
CN105663070A (zh) * | 2014-11-21 | 2016-06-15 | 深圳信立泰药业股份有限公司 | 一种含有奥美沙坦酯的药物组合物及其制备方法 |
CA3015964C (en) * | 2016-03-24 | 2021-08-03 | Daiichi Sankyo Company, Limited | Medicine for treating renal disease |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0578328A (ja) * | 1991-02-21 | 1993-03-30 | Sankyo Co Ltd | ビフエニルメチルイミダゾール誘導体 |
US5616599A (en) | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
WO2000000492A1 (fr) * | 1998-06-26 | 2000-01-06 | Chugai Seiyaku Kabushiki Kaisha | DERIVE D'ACIDE L-α-AMINOADIPIQUE EN POUDRE FINE, PREPARATIONS SOLIDES ORALES CONTENANT LEDIT DERIVE ET PROCEDE DE TRAITEMENT DE POUDRES EN VRAC |
WO2004110448A1 (ja) * | 2003-06-17 | 2004-12-23 | Kyowa Hakko Kogyo Co., Ltd. | 塩酸ベニジピン含有医薬組成物 |
JP2007031377A (ja) * | 2005-07-28 | 2007-02-08 | Nichi-Iko Pharmaceutical Co Ltd | 服用性に優れたグリメピリド含有薬剤 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060281800A1 (en) * | 2005-04-12 | 2006-12-14 | Glenmark Pharmaceuticals Limited | Polymorphic form of olmesartan and process for its preparation |
EP1910343B1 (en) * | 2005-07-29 | 2014-10-29 | Krka | Process for the preparation of olmesartan medoxomil |
-
2008
- 2008-03-19 JP JP2009506296A patent/JPWO2008117707A1/ja active Pending
- 2008-03-19 BR BRPI0809161-7A patent/BRPI0809161A2/pt not_active IP Right Cessation
- 2008-03-19 CA CA002681591A patent/CA2681591A1/en not_active Abandoned
- 2008-03-19 KR KR1020097019639A patent/KR20090122455A/ko not_active Application Discontinuation
- 2008-03-19 EP EP08722426A patent/EP2141160A4/en not_active Withdrawn
- 2008-03-19 CN CN200880017194A patent/CN101679390A/zh active Pending
- 2008-03-19 WO PCT/JP2008/055036 patent/WO2008117707A1/ja active Application Filing
- 2008-03-21 TW TW097109978A patent/TW200840565A/zh unknown
-
2009
- 2009-09-15 US US12/584,960 patent/US20100062070A1/en not_active Abandoned
- 2009-09-17 IL IL201007A patent/IL201007A0/en unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0578328A (ja) * | 1991-02-21 | 1993-03-30 | Sankyo Co Ltd | ビフエニルメチルイミダゾール誘導体 |
US5616599A (en) | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
WO2000000492A1 (fr) * | 1998-06-26 | 2000-01-06 | Chugai Seiyaku Kabushiki Kaisha | DERIVE D'ACIDE L-α-AMINOADIPIQUE EN POUDRE FINE, PREPARATIONS SOLIDES ORALES CONTENANT LEDIT DERIVE ET PROCEDE DE TRAITEMENT DE POUDRES EN VRAC |
WO2004110448A1 (ja) * | 2003-06-17 | 2004-12-23 | Kyowa Hakko Kogyo Co., Ltd. | 塩酸ベニジピン含有医薬組成物 |
JP2007031377A (ja) * | 2005-07-28 | 2007-02-08 | Nichi-Iko Pharmaceutical Co Ltd | 服用性に優れたグリメピリド含有薬剤 |
Non-Patent Citations (3)
Title |
---|
D. CHULIA ET AL.: "Powder Technology and Pharmaceutical Processes", 1 December 1993, ELSEVIER SCIENCE PUB CO |
SANKYO RESEARCH INSTITUTE ANNUAL REPORT, vol. 55, 2003, pages 12 - 15 |
See also references of EP2141160A4 |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010146408A3 (en) * | 2009-06-19 | 2011-08-11 | Nanoform Cardiovascular Therapeutics Ltd | Nanoparticulate olmesartan medoxomil compositions, process for the preparation thereof and pharmaceutical compositions containing them |
JP2012530126A (ja) * | 2009-06-19 | 2012-11-29 | ドラッガビリティ テクノロジーズ アイピー ホールドコ (ジャージー) リミテッド | ナノ粒子のオルメサルタンメドキソミル組成物、その調製方法、及びそれらを含有する医薬組成物 |
WO2011045760A2 (en) | 2009-10-13 | 2011-04-21 | Ranbaxy Laboratories Limited | Micronized olmesartan medoxomil compositions |
JP2016044170A (ja) * | 2014-08-27 | 2016-04-04 | 日本ケミファ株式会社 | オルメサルタンのプロドラッグ製剤 |
US20220133720A1 (en) * | 2019-02-26 | 2022-05-05 | Daewoong Pharmaceutical Co., Ltd. | Pharmaceutical composition of single dosage form for treating or preventing hypertension and hyperlipidemia |
Also Published As
Publication number | Publication date |
---|---|
IL201007A0 (en) | 2010-05-17 |
EP2141160A4 (en) | 2011-06-29 |
EP2141160A1 (en) | 2010-01-06 |
TW200840565A (en) | 2008-10-16 |
JPWO2008117707A1 (ja) | 2010-07-15 |
CN101679390A (zh) | 2010-03-24 |
US20100062070A1 (en) | 2010-03-11 |
CA2681591A1 (en) | 2008-10-02 |
BRPI0809161A2 (pt) | 2014-09-16 |
KR20090122455A (ko) | 2009-11-30 |
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