WO2008101690A2 - Implant destiné au traitement d'hernies - Google Patents

Implant destiné au traitement d'hernies Download PDF

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Publication number
WO2008101690A2
WO2008101690A2 PCT/EP2008/001330 EP2008001330W WO2008101690A2 WO 2008101690 A2 WO2008101690 A2 WO 2008101690A2 EP 2008001330 W EP2008001330 W EP 2008001330W WO 2008101690 A2 WO2008101690 A2 WO 2008101690A2
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WO
WIPO (PCT)
Prior art keywords
implant
plug
shaped element
flat
shaped
Prior art date
Application number
PCT/EP2008/001330
Other languages
German (de)
English (en)
Other versions
WO2008101690A3 (fr
Inventor
Robert Obermaier
Original Assignee
Universitätsklinikum Freiburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitätsklinikum Freiburg filed Critical Universitätsklinikum Freiburg
Publication of WO2008101690A2 publication Critical patent/WO2008101690A2/fr
Publication of WO2008101690A3 publication Critical patent/WO2008101690A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00632—Occluding a cavity, i.e. closing a blind opening

Definitions

  • the invention relates to an implant for closing of abdominal wall defects, consisting of at least one plug-shaped element, which can, at least largely, adapt to the interior of the gate of an abdominal wall defect to be closed and an areal extensively extending element which the area of the gate by resting on the said portal can cover surrounding tissue from inside the inside of the abdomen, as well as methods under its use, in particular for the laparoscopic treatment of abdominal wall defects, and kits containing such implants, in particular for laparoscopic purposes.
  • Hernias are, for example, entrained hernias with a sac-like protuberance of the parietal peritoneum in the form of a so-called hernia sac, often through anatomically preshaped abdominal wall gaps or weak points, the so-called hernias and the emergence of viscera or organ parts Depending on their localization, they are called hernia inguinalis (inguinal hernia, the most common and most common form in men, with an indirect form of hernia along the epigastric vessels through the inguinal canal the spermatic cord or ligament rotundum runs into the interior of the testis or labia majora area and a so-called "direct", which emerges to the outer groin ring outside the testis or the labia majora, next to the hernia femoralis sive cruralis as a special form of the Inguinal hernia, the umbilical hernia ("umb
  • Inguinal hernias are among the most common general-surgical diseases in Germany - there are approximately 200,000 inpatient inguinal hernias per year. The resulting costs for statutory health insurance in 2001 were around 400 million euros.
  • An established method of open surgical technique is the so-called patch and plug technique using biocompatible networks.
  • Current meta-analyzes show that the supply of biocompatible meshes, which closes the hernia portal by means of the mesh, is currently the safest method for the operative treatment of inguinal hernias in adults, either using the conventional (open mesh implantation, eg technique Lichtenstein, Rutkow's technique, each "from the front") or the laparoscopic technique (TAPP (for trans-abdominal preperceritoneal with access via the
  • TEP for
  • TEP total endoscopic pre-peritoneal hernioplasty
  • the laparoscope is inserted into the space between the large straight abdominal muscle and the peritoneum via the small navel wound, after dilating the two layers with a dilatation balloon and insufflating CO 2 -GaS into the space
  • two more working trocars are inserted in the midline below the navel.
  • Under view of the break bag can now be prepared from the hernia and prepared from the spermatic cord formations or from the round mother tape and thus completely dissolved.
  • the open surgery with mesh is in principle technically simpler, safer for the patient and cheaper for the hospital.
  • the open surgical technique seems to be somewhat more painful in the postoperative period, and the patients need a longer convalescence period to restore their ability to work.
  • the laparoscopic mesh implantation has the disadvantage of a more difficult or expensive surgical technique, the expenditure on equipment is greater, and although complications are not more frequent compared to open surgery, they can be more serious and dangerous for the patient. Plus, the cost of the surgery - A -
  • this method has advantages such as low postoperative pain, rapid postoperative mobilization, low rate of wound healing disorders, low complication and recurrence rates, early exercise, rapid diet and short term inpatient stay.
  • plugs stuffing (or grafting) shaped elements
  • plug technique in which a rupture gate channel is made of a biocompatible plug Material is placed, in which then surrounding tissue can grow, which leads to stabilization.
  • the plug-in technique is conventionally used worldwide with good results, but a laparoscopic plug-in method is currently not possible because the plugs on the market are not permanently in direct contact with e.g. allowed to enter the intestine (risk of fistula formation).
  • DE 694 15 060 T2 (corresponding to EP 0 614 650 B1) discloses implantable plugs made of a polypropylene monofilament braid which are suitable for filling and restoring muscle and tissue wall fractures and to the irregularities of the shape can adapt to such a defect.
  • the object of the present invention is therefore to provide a new method and new implants which, in addition to open surgical procedures, also enable laparoscopic use and, in particular, have further advantages.
  • an implant described above which is characterized in that the plug-shaped and the planar-extended element are designed as a combination and the planar-extended element has an anti-adhesive surface at least on its side facing the inside of the abdomen.
  • the invention relates to a method or a method for the treatment of an abdominal wall defect, in particular of a hernia, which is characterized in that it comprises an implant designed according to the invention in the form of said combination of a stopper-shaped element and a surface-extended element, Preferably, laparoscopically and within the peritoneum, as seen from the inside of the abdomen, without it Removal from the area of the defect, placing the plug-shaped portion in the area of the (fractional) gate of the defect, especially in a patient who needs such treatment, is used.
  • an implant or a kit which is defined below or in the claims, in particular the subclaims or the embodiments characterized as being preferred, is used.
  • the invention also relates to a kit which includes one or more (for example in different sizes) multiple plug-shaped elements and areal-shaped elements for (for example preoperatively taking into account parameters of the respective defect) production of an implant according to the invention.
  • the elements of the kit have such features which are mentioned below or in the claims for preferred implants.
  • an implant according to the invention comprises different materials or equipment on the side facing the defect, in particular in the area of the plug-shaped element, and in the region which faces the inside of the stomach.
  • one or more of these are present Materials which allow connection to the surrounding tissue, in particular to allow adherence or, preferably, ingrowth of the surrounding tissue, in particular as one or more surrounding tissue (distal from the abdominal cavity) (thus surrounding tissue or parts of organs, such as inter alia Fat or muscle tissue or portions of the peritoneum or skin cells) infiltratable materials, ie one or more biocompatible, bendable materials, preferably having a plurality of pores, spaces or openings, for example a network structure, such as textile5.3nma materials, in particular, such as felts, braids, cast products, knitted fabrics, chain textile or fabrics, for example, in each case from poly propylene such as BARD MESH from Bard Inc., SURGIPRO from US Surgical, Inc., TRELEX from Boston
  • absorbable materials such as e.g. Polylactin (eg VICRYL from Ethicon, Inc.) polyglycolate (eg DEXON from US Surgical, Inc.), polydioxanone (PDS), polyglyconate (eg MAXON, Davis & Geck, Gosport, UK) or collagen materials such as COOK SURGISIS from the company Cook Biomedical, Inc. are possible, but non-absorbable materials are preferred in one possible embodiment of the invention.
  • Polylactin eg VICRYL from Ethicon, Inc.
  • polyglycolate eg DEXON from US Surgical, Inc.
  • PDS polydioxanone
  • polyglyconate eg MAXON, Davis & Geck, Gosport, UK
  • collagen materials such as COOK SURGISIS from the company Cook Biomedical, Inc.
  • an implant according to the invention at least on its side facing the inside of the stomach or at least on its surface, has an antiadhesive finish (barrier), for example by coating or by at least the side of the areal extended element of an antiadhesive Material exists.
  • an antiadhesive finish for example by coating or by at least the side of the areal extended element of an antiadhesive Material exists.
  • Antiadhesive means that there is a barrier (in the form of the entire material or at least its exposed portions or surfaces in vulnerable areas), the regions of potential unwanted adhesion or unwanted ingrowth (tissue seen from the inside of the implant proximal to the implant), like that Abdominal viscera (eg, intestines) or thoracic viscera (such as lungs or heart) facing sides of the implant shields against unwanted ingrowth of (at least parts) of the tissues or organs concerned.
  • a barrier in the form of the entire material or at least its exposed portions or surfaces in vulnerable areas
  • the regions of potential unwanted adhesion or unwanted ingrowth tissue seen from the inside of the implant proximal to the implant
  • Abdominal viscera eg, intestines
  • thoracic viscera such as lungs or heart
  • a corresponding barrier is in particular designed such that its structure and / or material does not stimulate ingrowth of such tissues or organs or parts thereof and in particular their ingrowth and the formation of an adhesion and / or infiltration by resist and thus an undesirable postoperative Adherence and ingrowth of adjacent tissue and / or organs (which includes corresponding cells) substantially, ie, in particular to or in appropriately exposed and protected areas of the planar expanded element sufficient, or preferably (at least practically) completely prevented.
  • planar expanded element then comes to lie with its anti-adhesively equipped area within the peritoneum and can come into direct contact with the local organs and tissues, for example the intestine, without, however, being able to adhesively bond or grow together in a disturbing manner plug-shaped element projecting into the area of the defect Support area of the peritoneum outward and can grow together with this and the surrounding areas.
  • laparoscopic methods For a particularly simple use in laparoscopic methods is possible, which are significantly simplified compared to the usual methods and (for example, since the peritoneum must not beumbleprppariert from the fracture area) show a lower risk of complications, so that corresponding embodiments of the invention are particularly preferred.
  • the antiadhesive equipment can be applied as a on the inside of the belly facing barrier layer on the rest of the surface formed element, or this can be completely surrounded by a corresponding material or made of it.
  • Suitable materials for such a barrier are stretched polytetrafluoroethylene (ePTFE) having pore sizes or internodal spacings which permit virtually no ingrowth, for example, with pore sizes of 5 ⁇ m or less, more preferably 1 ⁇ m or less, preferably 0.5 ⁇ m or less, such as, for example "FLUORO-TEX Pericardial and Peritoneum Surgical Membrane" (FLUORO-TEX Surgical Membrane for Pericardium and Peritoneum) or FLUORO-TEX Dura Substitute (FLUORO-TEX Dura Replacement) each from CR.
  • ePTFE stretched polytetrafluoroethylene
  • PRECLUDE Pericardial Membrane Bard or PRECLUDE Pericardial Membrane (PRECLUDE Pericardial Membrane). Membrane), PRECLUDE Peritoneal Membrane (PRECLUDE Peritoneal Membrane) and PRECLUDE Dura Substitute Membrane (PRECLUDE Dura Replacement Membrane), each from WL Gore & Associates, other materials include silicone elastomers, such as SILASTIC Rx Medical Grade Sheeting ( SILASTIC Rx covers for medical purposes) from Dow Corning (platinum catalyst-cured) or microporous polypropylene, as available from Celgard, Inc., for example. Also two or more of these materials, or other suitable materials, can be used. Corresponding coatings are also conceivable, especially on the side facing away from the defect to be treated and facing the abdominal interior.
  • SILASTIC Rx covers for medical purposes from Dow Corning (platinum catalyst-cured) or microporous polypropylene, as available from Celgard, Inc
  • the plug-shaped element and the flat element can be provided in a form that can be connected to one another only during implantation, for example as a kit (which may also include a material such as thread or the like for connecting the elements) or even as individual products which are provided for combination, which allows a high flexibility, for example, in terms of the size ratios of the two elements and the adaptation to a specific defect, or they are preferably already previously firmly connected to each other, ie in particular (at least under normal circumstances and without destruction) inextricably linked.
  • the invention is not limited to certain types of fastening, but there are all suitable types of attachment conceivable, such as attachment to each other by sewing, for example by means of seams and / or individual stitches stitches with suitable yarns, by fusing / welding
  • kits according to the invention wherein the compound only in sections, for example, according to a solid pattern or without a solid pattern (for example, spiral, serpentine, latticed, punctiform or linear), executed, or by other attachment methods, or combinations of two or more such attachment methods realized can be.
  • the combination according to the invention of the plug-shaped element and the flat element is made in one piece.
  • the plug-shaped element can "at least largely conform to the interior of the gate of a closure of the abdominal wall to be closed" means, in the first place, that it has a shape or can be brought into a shape during an operation that is largely or practically completely the dimensions of the interior corresponds to the gate (breakage gate) of the defect to be treated and so can fill the entire or at least a considerable part, for example more than 80%, in particular more than 90%, of the defect, preferably in the expanded state an approximately conical or approximately frusto-conical shape
  • correspondingly folded textile structures such as single-layer or multi-layer fabric plaits, for example analogously to the type shown in DE 694 15 060, which is hereby incorporated herein by reference in one or more parts (for example with outer skin sections and if desired (for example to E Increasing the rigidity) one or more within it located packing of filling materials, which may also consist of corresponding cloth meshes) can be achieved.
  • a certain elasticity may be advantageous, for example, an insertion (in particular laparoscopic) in the gate area in a state of tapered ("compressed") outer diameter, and after placement, to allow expansion toward the inner edge of the gate, any suitable materials are conceivable, eg as mentioned above for the plug-shaped element, and (at least in the outer region)
  • the plug-shaped element may also be hollow, and may advantageously be closed in the distal part (furthest from the plane-extending element) or may be open there to prevent ingrowth from surrounding tissue Further facilitate tissue.
  • Extended in area preferably means that the correspondingly characterized element has two opposing outward surfaces which are interconnected by a region of substantially reduced thickness perpendicular to said surfaces and their diameters
  • the surfaces need not be completely flat.
  • they may be configured to be at least substantially, that is, for example, with deviations of not more than twice the thickness from the location of the smallest thickness, but one or both (for example, in the case of the abdominal interior, outer surface) of the surfaces may be slightly concave in whole or in one or more regions and / or (in particular in the case of the abdominal surface) and shaped in particular in the inoperated state according to anatomical conditions.
  • planar element is large enough to ensure covering of a (for example fracture) portal of a defect of a stomach wall and the plug-shaped element and at least in partial areas overlapping with outside the diameter of the passage area (gate)
  • the diameter of the flatly extended element in a plane parallel to the opposite surfaces is at least in some areas, preferably everywhere, larger than the diameter of the door to be supplied and always larger than the diameter of the base portion of an associated plug-shaped element, for example at least 1.2 sometimes as large, preferably 1.3 to 8 times as large, for example 1.5 to 5 times larger.
  • the areal expanded element may be polygonal or round, e.g. oval or circular, be executed.
  • An implant according to the invention may comprise one (preferred) or several stopper-shaped elements, for example a plurality if more than one porthole and / or one elongated porthole gate is to be supplied, in which case the two-dimensionally expanded element covers two or more such stopper-shaped elements can.
  • the plug-shaped element has (especially in the inserted state directly after an operation) perpendicular to its Longitudinal axis (and parallel to a plane which is parallel to the opposing surfaces of the planar-extended element) has a diameter which is not larger and at least in partial areas smaller than the diameter of the adjacent opposite surfaces of the planar-extended element, for example alternative to previous information about 75% or less, advantageously 10% to 70%, for example, 20% (or 30%) to 60% of the diameter of this area, measured at the contact area between the plug-shaped and the flat-extending element (distally thereof, the plug-shaped Element continues to rejuvenate).
  • the one or more plug-shaped elements is or are arranged so that their widest connection area (base area) is completely covered with the planar expanded element from the inside of the belly and at least in partial areas, advantageously all around, is surmounted by the contacted surface of the sheet-like element to the outside.
  • this element is arranged at least approximately centrally on the flat element and protrudes outwards on all sides thereof.
  • the flatly extended element advantageously has such an elastic tension that it strives for a substantially planar shape in the free state. It is also possible that only a self-contained (for example ring-shaped) outer (edge) region (which can be embodied, in particular, as an integral component or as a separate ring element fastened in the outer region of the extensively extended element) of the flatly extended element is such having elastic tension.
  • the elastic tension allows a reduction (compression) for insertion and a subsequent expansion over the gate area to be closed, so that a good usability, especially in laparoscopic use, is ensured.
  • the implant according to the invention and the kits and methods or methods according to the invention are suitable for use on patients who suffer from an abdominal wall defect, in particular a hernia.
  • Patients are to be understood as meaning, in particular, humans, but also generally vertebrates.
  • Fig. 1 is a schematically illustrated in lateral plan inventive implant in the abdominal wall shown in cross-section (bulge in the skin area for
  • FIG. 2 is a schematic view of an implant according to the invention in an oblique view from the side of the flatly extended element;
  • FIG. 3 is a schematic view of an implant according to the invention viewed obliquely from the side of the plug-shaped element;
  • FIG. 4 schematically shows an implant according to the invention as viewed from the side of the extensively extended element, the connection area concealed by the latter between the plug-shaped and planar-extended elements being roughly semitransparent with dotted lines, and crosses showing some schematically represented points for connecting seams (eg nodes) mean.
  • FIG. 1 shows an example of implant 6 according to the invention, which consists of a plug-shaped element 8 and a surface-extended element 7 and in the abdominal wall with the skin 1, the fatty tissue 2, a region of an abdominal wall defect, here represented as the area of a hernia 3, the peritoneum 4 and a traversed by fracture muscle and / or tendon area 5 is already introduced as far as possible.
  • the extensively extended element 7 completely covers the area of the hernial gate 3 from the inside and also covers adjacent intact areas.
  • the sheet-like member 7 has at least on the side facing away from the peritoneum anti-adhesive equipment to adhere or coalesce with organs or tissues that can come into contact with it from the inside of the abdominal cavity prevent, while the plug-shaped element 8 should at least partially made of a suitable materials for connection to surrounding tissues, to allow a good postoperative fixation.
  • the plug-shaped element 8 is sufficiently rigid and on the other hand sufficiently dimensionally stable, for example, due to a folded structure as shown, but which may also be replaced by any other suitable structure, largely to fill the inner region of the abdominal wall defect to be closed, and it is in the field Base preferably firmly connected to the sheet-like element 7, for example by stitching, pinholes (eg with knots of a suitable yarn, which, when it comes to rest on the inside of the abdominal surface is also anti-adhesive equipped) as shown by the crosses in Fig. 4 indicated, or in any other suitable manner. As shown in FIGS.
  • the planar element may have an elastic tensioning region 9 (in this case, for example, in the form of a ring) or may itself have enough inherent elasticity to prevent it from being introduced (for example when compressed State) to allow a planar expansion of the sheet-like element.
  • Fig. 2 and Fig. 3 illustrate examples of the positional relationship of the plug-shaped element 8 and the flat-extended element 7.
  • the plug-shaped element can also be designed in cross section with a straight or otherwise curved surface as shown, which is a suitable adaptation to the respective to be rehabilitated Abdominal wall defect and its shape allows.
  • the contact region 10 between the elements 7 and 8 is indicated by dashed lines, which, however, can also be arbitrarily shaped differently.
  • an implant 6 according to the invention can also be formed in one piece, in particular in the connection region of the elements 7 and 8.

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  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne un implant (6) destiné à obturer des anomalies de la paroi abdominale, lequel implant est composé d'au moins un élément sous forme de bouchon (8), pouvant s'adapter au moins dans une large mesure à la zone interne de l'orifice d'une anomalie de la paroi abdominale à obturer, et d'un élément plan (7), pouvant recouvrir totalement, de l'intérieur, la zone de l'orifice en s'appuyant sur le tissu entourant l'orifice susmentionné, vu de la face interne du ventre. L'implant se caractérise en ce que les deux éléments (7, 8) sont associés l'un à l'autre et l'élément plan (7) comporte un apprêt anti-adhésif au moins sur son côté faisant face à l'intérieur du ventre. Cet implant est particulièrement adapté à des méthodes et des procédés laparoscopiques simplifiés. L'invention concerne également des trousses correspondantes.
PCT/EP2008/001330 2007-02-21 2008-02-20 Implant destiné au traitement d'hernies WO2008101690A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200710008538 DE102007008538A1 (de) 2007-02-21 2007-02-21 Implantat für die Behandlung von Hernien
DE102007008538.0 2007-02-21

Publications (2)

Publication Number Publication Date
WO2008101690A2 true WO2008101690A2 (fr) 2008-08-28
WO2008101690A3 WO2008101690A3 (fr) 2008-11-06

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ID=39645803

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/001330 WO2008101690A2 (fr) 2007-02-21 2008-02-20 Implant destiné au traitement d'hernies

Country Status (2)

Country Link
DE (1) DE102007008538A1 (fr)
WO (1) WO2008101690A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9820838B2 (en) 2012-04-10 2017-11-21 Ethicon, Inc. Single plane tissue repair patch
US9820839B2 (en) 2012-04-10 2017-11-21 Ethicon, Inc. Single plane tissue repair patch having a locating structure
US9820837B2 (en) 2012-04-10 2017-11-21 Ethicon, Inc. Single plane tissue repair patch

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011102039A1 (de) * 2011-05-19 2012-11-22 Feg Textiltechnik Forschungs- Und Entwicklungsgesellschaft Mbh Implantat

Citations (3)

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US5116357A (en) * 1990-10-11 1992-05-26 Eberbach Mark A Hernia plug and introducer apparatus
US20040260401A1 (en) * 2003-06-18 2004-12-23 Crawley Jerald M. Soft tissue defect repair device
US20060015143A1 (en) * 2004-07-19 2006-01-19 Alfredo Alvarado Laparoscopic inguinal hernia prosthesis

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US5356432B1 (en) 1993-02-05 1997-02-04 Bard Inc C R Implantable mesh prosthesis and method for repairing muscle or tissue wall defects
FR2767671B1 (fr) * 1997-08-27 1999-11-26 Ethnor Dispositif obturateur prothetique pour l'obturation de canaux herniaires
US6241768B1 (en) * 1997-08-27 2001-06-05 Ethicon, Inc. Prosthetic device for the repair of a hernia
JP2000107286A (ja) 1998-10-07 2000-04-18 Akira Sakai 腹膜透析液の灌流装置及び灌流法
FR2808437B1 (fr) * 2000-05-05 2002-10-25 Cousin Biotech Prothese de reparation herniaire
DE10106546A1 (de) * 2001-02-13 2002-08-22 Ethicon Gmbh Verfahren zum Herstellen eines medizinischen Implantats
US6712859B2 (en) * 2001-06-28 2004-03-30 Ethicon, Inc. Hernia repair prosthesis and methods for making same
FR2829922B1 (fr) * 2001-09-21 2004-06-18 Sofradim Production Implant complet et universel pour la reparation des hernies par voie anterieure
DE10318801A1 (de) * 2003-04-17 2004-11-04 Aesculap Ag & Co. Kg Flächiges Implantat und seine Verwendung in der Chirurgie
EP1773238A1 (fr) * 2004-07-20 2007-04-18 Stephen G. E. Barker Prothese de reparation de hernie ombilicale ou paraombilicale

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116357A (en) * 1990-10-11 1992-05-26 Eberbach Mark A Hernia plug and introducer apparatus
US20040260401A1 (en) * 2003-06-18 2004-12-23 Crawley Jerald M. Soft tissue defect repair device
US20060015143A1 (en) * 2004-07-19 2006-01-19 Alfredo Alvarado Laparoscopic inguinal hernia prosthesis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9820838B2 (en) 2012-04-10 2017-11-21 Ethicon, Inc. Single plane tissue repair patch
US9820839B2 (en) 2012-04-10 2017-11-21 Ethicon, Inc. Single plane tissue repair patch having a locating structure
US9820837B2 (en) 2012-04-10 2017-11-21 Ethicon, Inc. Single plane tissue repair patch

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Publication number Publication date
WO2008101690A3 (fr) 2008-11-06
DE102007008538A1 (de) 2008-08-28

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