WO2008084331A3 - Biomarqeurs pour des troubles rénaux - Google Patents

Biomarqeurs pour des troubles rénaux Download PDF

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Publication number
WO2008084331A3
WO2008084331A3 PCT/IB2007/004395 IB2007004395W WO2008084331A3 WO 2008084331 A3 WO2008084331 A3 WO 2008084331A3 IB 2007004395 W IB2007004395 W IB 2007004395W WO 2008084331 A3 WO2008084331 A3 WO 2008084331A3
Authority
WO
WIPO (PCT)
Prior art keywords
biomarkers
renal disorders
developing
patient
risk
Prior art date
Application number
PCT/IB2007/004395
Other languages
English (en)
Other versions
WO2008084331A2 (fr
Inventor
Solange Moll
Denis Hochstrasser
Pierre Lescuyer
Catherine Zimmermann
Original Assignee
Hopitaux Universitaires De Gen
Solange Moll
Denis Hochstrasser
Pierre Lescuyer
Catherine Zimmermann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hopitaux Universitaires De Gen, Solange Moll, Denis Hochstrasser, Pierre Lescuyer, Catherine Zimmermann filed Critical Hopitaux Universitaires De Gen
Publication of WO2008084331A2 publication Critical patent/WO2008084331A2/fr
Publication of WO2008084331A3 publication Critical patent/WO2008084331A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention porte sur des procédés pour déterminer si un patient a ou est à risque de développer un trouble rénal. Dans certains modes de réalisation, des biomarqueurs spécifiques sont fournis, lesquels peuvent être utilisés pour déterminer si un patient a ou est à risque de développer un trouble rénal (par exemple, une insuffisance rénale aiguë).
PCT/IB2007/004395 2006-06-21 2007-06-20 Biomarqeurs pour des troubles rénaux WO2008084331A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80541406P 2006-06-21 2006-06-21
US60/805,414 2006-06-21
US86673306P 2006-11-21 2006-11-21
US60/866,733 2006-11-21

Publications (2)

Publication Number Publication Date
WO2008084331A2 WO2008084331A2 (fr) 2008-07-17
WO2008084331A3 true WO2008084331A3 (fr) 2009-04-23

Family

ID=39609106

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/004395 WO2008084331A2 (fr) 2006-06-21 2007-06-20 Biomarqeurs pour des troubles rénaux

Country Status (1)

Country Link
WO (1) WO2008084331A2 (fr)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005070086A2 (fr) 2004-01-21 2005-08-04 The Board Of Trustees Of The Leland Stanford Junior University Procedes et compositions pour la determination de phenotype a tolerance vis-a-vis du greffon chez un sujet
USRE46843E1 (en) 2005-03-14 2018-05-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for evaluating graft survival in a solid organ transplant recipient
WO2006099421A2 (fr) 2005-03-14 2006-09-21 The Board Of Trustees Of The Leland Stanford Junior University Procedes et compositions permettant d'evaluer la survie d'un greffon chez un destinataire d'une transplantation d'organe solide
WO2006116451A2 (fr) 2005-04-22 2006-11-02 Morphotek, Inc. Anticorps a activite d'effecteur immunitaire et internalises dans des cellules positives vis-a-vis de l'endosialine
RS55447B1 (sr) 2007-04-05 2017-04-28 Morphotek Inc Metode za inhibiranje vezivanja endosijalina za ligande
KR20100105776A (ko) 2008-01-18 2010-09-29 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 체액 내에서 질병 또는 병태의 시그너쳐의 검출 방법
US20110201519A1 (en) 2008-08-18 2011-08-18 Sarwal Minnie M Methods and Compositions for Determining a Graft Tolerant Phenotype in a Subject
KR20110073471A (ko) 2008-08-28 2011-06-29 아스튜트 메디컬 인코포레이티드 신손상 및 신부전의 진단 및 예후를 위한 방법 및 조성물
EP2324354B1 (fr) 2008-08-29 2014-07-16 Astute Medical, Inc. Procédés pour le pronostic d'une insuffisance rénale acute
EP3246707B1 (fr) * 2008-10-21 2020-09-30 Astute Medical, Inc. Procédés et compositions de diagnostic et de pronostic de lésion rénale et d'insuffisance rénale
CN104330574B (zh) 2008-11-10 2017-04-12 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
EP2387618B1 (fr) 2009-01-15 2014-05-21 The Board of Trustees of The Leland Stanford Junior University Panel de biomarqueurs pour le diagnostic et la prédiction d'un rejet de greffon
US9229010B2 (en) 2009-02-06 2016-01-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2011017654A1 (fr) 2009-08-07 2011-02-10 Astute Medical, Inc. Procédés et compositions pour le diagnostic et le pronostic d'une lésion rénale et d'une insuffisance rénale
DE102009010563A1 (de) 2009-02-16 2010-08-26 Matthias W. Engel Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten
WO2010143423A1 (fr) * 2009-06-10 2010-12-16 国立大学法人 新潟大学 Méthode de détection d'une néphropathie diabétique
EP2475989A4 (fr) 2009-09-09 2013-02-27 Gen Hospital Corp Utilisation de microvésicules dans l'analyse de mutations kras
EP2475988B1 (fr) 2009-09-09 2018-11-14 The General Hospital Corporation Utilisation de microvésicules dans l'analyse de profils d'acide nucléique
US20130045494A1 (en) * 2009-09-18 2013-02-21 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ704383A (en) * 2009-09-21 2016-09-30 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP2013510322A (ja) 2009-11-07 2013-03-21 アスチュート メディカル，インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
EP3185013B1 (fr) 2009-12-02 2019-10-09 The Board of Trustees of the Leland Stanford Junior University Biomarqueurs pour déterminer un xénotype tolérant à l'allogreffe
CN102725636B (zh) 2009-12-20 2015-04-01 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断及预后的方法和组合物
US20130230871A1 (en) * 2010-02-05 2013-09-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
BR112012019542A2 (pt) 2010-02-05 2018-03-27 Astute Medical Inc "método para avaliar o estado renal em um indivíduo, medição de um ou mais biomarcadores, e, kit"
EA201290711A1 (ru) 2010-02-26 2013-10-30 Астьют Медикал, Инк. Способы и композиции для диагностики и прогнозирования повреждений почек и почечной недостаточности
US9535075B2 (en) 2010-03-25 2017-01-03 The Board Of Trustees Of The Leland Stanford Junior University Protein and gene biomarkers for rejection of organ transplants
NZ605698A (en) 2010-06-23 2015-03-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ703055A (en) 2010-06-23 2016-07-29 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US20130203624A1 (en) 2010-07-23 2013-08-08 President And Fellows Of Harvard College Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions
CA2806310A1 (fr) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Methodes de depistage de maladies ou d'affections a l'aide de cellules phagocytaires
CA2806291C (fr) 2010-07-23 2023-08-29 President And Fellows Of Harvard College Procedes de detection de signatures de maladies ou pathologies dans des liquides biologiques
CA2806293A1 (fr) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Procedes de detection de maladies/pathologies auto-immunes ou liees au systeme immunitaire
WO2012012704A2 (fr) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Procédés de détection de maladies ou d'états associés au rein
WO2012031008A2 (fr) 2010-08-31 2012-03-08 The General Hospital Corporation Matières biologiques liées au cancer dans des microvésicules
EP2638057B1 (fr) 2010-11-10 2019-03-06 Exosome Diagnostics, Inc. Procédés d'isolement de particules contenant des acides nucléiques et extraction d'acides nucléiques à partir de celles-ci
ES2382960B1 (es) * 2010-11-18 2013-05-08 Universidad De Jaén Aminopeptidasas como marcadores de daño renal
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
WO2012139051A2 (fr) 2011-04-06 2012-10-11 The Board Of Trustees Of The Leland Stanford Junior University Biomarqueurs d'auto-anticorps pour néphropathie iga
EP2788759B1 (fr) 2011-12-08 2019-02-20 Astute Medical, Inc. Procédés et utilisations permettant de diagnostiquer une lésion des reins et une insuffisance rénale
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
ES2681955T3 (es) 2013-01-17 2018-09-17 Astute Medical, Inc. Métodos y composiciones para el diagnóstico y pronóstico de lesión renal e insuficiencia renal
WO2014164366A1 (fr) 2013-03-09 2014-10-09 Harry Stylli Procédés de détection de cancer
EP2965086A4 (fr) 2013-03-09 2017-02-08 Harry Stylli Procédés de détection du cancer de la prostate
ES2528672B1 (es) * 2013-07-10 2015-11-24 Consejo Superior De Investigaciones Científicas (Csic) Neurofilina-1 (NRP-1) urinaria como marcador pronóstico de nefritis y nefritis lúpica
CN108051590B (zh) 2013-09-13 2020-12-11 Symbolics有限责任公司 运用二维试验和对照信号读出模式的侧向层析检测
JP2017513009A (ja) 2014-04-09 2017-05-25 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 免疫評価および移植片拒絶の予測のためのタンパク質バイオマーカー
US20170205427A1 (en) * 2014-07-23 2017-07-20 University Of British Columbia Biomarkers for anderson-fabry disease
EP3693742B1 (fr) 2014-09-11 2022-04-06 Harry Stylli Procédés pour détecter le cancer de la prostate
US11243217B2 (en) 2016-06-06 2022-02-08 Astute Medical, Inc. Management of acute kidney injury using insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase 2
US11346846B2 (en) 2017-02-06 2022-05-31 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN114324887A (zh) * 2021-10-14 2022-04-12 深圳市华启生物科技有限公司 免疫球蛋白a肾病t细胞诊断标志物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082202A2 (fr) * 2002-03-28 2003-10-09 The Regents Of The University Of Michigan Techniques et compositions destinees a l'analyse d'echantillons d'urine en vue du diagnostic et du traitement de maladie renales
EP1604990A1 (fr) * 2004-06-11 2005-12-14 National Health Research Institutes Alkaloides de Phenanthroindolizidine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003082202A2 (fr) * 2002-03-28 2003-10-09 The Regents Of The University Of Michigan Techniques et compositions destinees a l'analyse d'echantillons d'urine en vue du diagnostic et du traitement de maladie renales
EP1604990A1 (fr) * 2004-06-11 2005-12-14 National Health Research Institutes Alkaloides de Phenanthroindolizidine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MERRITT S E ET AL: "ANALYSIS OF ALPHA-1 I PROCOLLAGEN ALPHA-1 IV COLLAGEN AND BETA ACTIN MESSENGER RNA IN GLOMERULUS AND CORTEX OF RABBITS WITH EXPERIMENTAL ANTI-GLOMERULAR BASEMENT MEMBRANE DISEASE EVIDENCE FOR EARLY EXTRAGLOMERULAR COLLAGEN BIOSYNTHESIS", LABORATORY INVESTIGATION, UNITED STATES AND CANADIAN ACADEMY OF PATHOLOGY, BALTIMORE, US, vol. 63, no. 6, 1 January 1990 (1990-01-01), pages 762 - 769, XP009108335, ISSN: 0023-6837 *

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