WO2008083418A1 - Élément optique - Google Patents

Élément optique Download PDF

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Publication number
WO2008083418A1
WO2008083418A1 PCT/AT2008/000002 AT2008000002W WO2008083418A1 WO 2008083418 A1 WO2008083418 A1 WO 2008083418A1 AT 2008000002 W AT2008000002 W AT 2008000002W WO 2008083418 A1 WO2008083418 A1 WO 2008083418A1
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WO
WIPO (PCT)
Prior art keywords
optical element
intensity distribution
eye
retina
intensity
Prior art date
Application number
PCT/AT2008/000002
Other languages
German (de)
English (en)
Inventor
Anton Ennemoser
Original Assignee
Anton Ennemoser
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anton Ennemoser filed Critical Anton Ennemoser
Publication of WO2008083418A1 publication Critical patent/WO2008083418A1/fr

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Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C2202/00—Generic optical aspects applicable to one or more of the subgroups of G02C7/00
    • G02C2202/24—Myopia progression prevention

Definitions

  • the invention relates to an optical element, preferably spectacles, contact lens or intraocular lens, for use in the correction of myopia or hyperpiegies, wherein the optical element alters the intensity distribution of incident electromagnetic radiation on the retina of a user's eye. Moreover, the invention relates to a method for producing an optical element.
  • myopia axial myopia
  • the myopia can basically be divided into two forms: on the one hand in a refractive myopia, in which the refractive power of the eye is too high, but the axial length is in the norm, on the other hand in an axial myopia, in which the eye is too long.
  • the focal point of rays incident in parallel to the eye is in front of the retina.
  • the second form is referred to as benign progressive myopia, in which stabilization does not occur until the age of 30, whereby values up to - 12D can be achieved.
  • the third form is malignant progressive myopia, which is a chronic disease that progresses independently of currently known external influences. In malignant progressive myopia, values as low as -30D can be achieved. In malignant progressive myopia, all layers of the eye - from the retina to the choroid to the sclera - show characteristic changes.
  • the frequency of myopia in children is over 90% in Japan, between 70% and 80% in Singapore, and around 70% in Taiwan and South Korea. In Taiwan, about 15% of the population is more than
  • the object of the present invention is therefore to provide an adjunct with which the problems occurring due to myopia or hyperopia can be reduced.
  • an optical element preferably spectacle lens, contact lens or intraocular lens
  • the optical element changes the intensity distribution of incoming electromagnetic radiation on the retina of a user's eye, wherein the optical element has regions with different transmittance, the intensity distribution of the To change the electromagnetic radiation incident on the retina such that in a refractive corrected myopic eye, an intensity distribution of a myopic eye can be achieved.
  • an optical element preferably a spectacle lens, contact lens or intraocular lens
  • the optical element changes the intensity distribution of incoming electromagnetic radiation on the retina of a user's eye, characterized in that the optical element has regions with different transmittance Change the intensity distribution of the incident on the retina electromagnetic radiation such that in a refractive hyperopic eye, an intensity distribution of a hyperopic eye can be achieved.
  • Refractive correction means that visual acuity is transferred to an emmetropic eye in a hyperopic or myopic eye. For example, in the eye with a certain myopia using a negative lens, the visual acuity is again corrected to OD.
  • the invention is based on the finding that the intensity distribution of the electromagnetic radiation incident on the retina exerts an influence on the growth of growth or factors which influence the growth of the eye's length. With the invention, at least a progression of myopia can be prevented, a normal vision, which is absent in severe hyperopia, can be induced.
  • the correction of the intensity distribution can be over-corrected, ie the regions of different transmittance not only correct the erroneous intensity distribution to the original myopen or hyperopen state, but also to a stronger myopen or hyperopen state.
  • visual acuity is refractive corrected by a conventional negative lens of the appropriate thickness (transition to the emmetropic state).
  • the intensity distribution of the electromagnetic radiation correct in the myopic eye is changed by the lens, which can subsequently lead to a worsening of the myopia.
  • the The "false" intensity distribution at the retina caused by the lens is transformed back into the intensity distribution of a myopic eye (eg -3D), ideally at least into the intensity distribution of the original (uncorrected) eye (-7D)
  • Intensity distribution to -10D would be corrected to achieve a longer-term improvement of myopia or analogous to the hyperopia (by controlling the length growth factors of the eye).
  • the areas with different degrees of transmission are achieved by a filter.
  • the above object is also achieved by a method of manufacturing an optical element.
  • the method is as follows: Method for producing an optical element, preferably spectacles, contact lens or intraocular lens, for use in correcting ametropia of an eye, wherein an actual intensity distribution profit of incident electromagnetic radiation on the retina of a user is determined as a function of the ametropia is compared with a desired intensity distribution profile, wherein the optical element is provided with a filter which converts the actual intensity distribution profile into the desired intensity distribution profile.
  • the filter can be subsequently applied by coating or applying absorbent materials. It is equally conceivable to introduce absorbing substances into the optical element which are already integrated in the production. These may be dyes, etc.
  • the optical element is made of plastic by polymerization, substances absorbing in the relevant wavelength range could be included. Even with optical elements made of glass, the dyes could be incorporated directly. It is favorable in any case, the absorption in the range of visible light (electromagnetic radiation of a Wavelength from 380 to 780 nm), ie that the transmission in the range 380 to 780 nm as a function of the wavelength is substantially constant.
  • 1 shows a perimeter P for determining the visual field of an eye on the left, right retina / eye
  • FIG. 2 shows two representations of perimeters with electromagnetic radiation incident parallel to the optical axis of the eye and refracted by the optical system of the eye (FIG. 2A) and central rays which pass unbroken through the optical system of the eye (FIG. 2B),
  • FIG. Figure 3 shows the image of electromagnetic radiation behind the optical system of the
  • FIG. 5 shows the intensity distribution for myopia, emmetropia and the difference intensity
  • FIG. 6 shows the intensity distribution for hyperopia, emmetropia and the difference intensity
  • FIG. 7 shows 1 normalized intensity distributions for myopia (FIG. 7A) and an enlargement of the difference Intensity (Fig. 7B) and Fig. 8 to 1 normalized intensity distributions for hyperopia (Fig. 3A) and an increase in difference intensity (Fig. 8A).
  • Fig. 1 reference characters P are perimeter, R is retina, O is optical system, r is position vector of retina, t is tangent vector, n is normal vector, x f is focal length, a is axial length of eye Poynting vectors (shown without arrows). A detailed description of Fig. 1 can be found below.
  • FIG. 2A shows parallel beams focused at the focal point and Fig. 2B central beams which pass unbroken through the optical system.
  • FIG. 3 shows central and parallel rays (shown thick here) intersecting behind the lens at the point of convergence P c , which is the construction point of the Poynting vectors emanating from a point P 0 and obliquely through the optical System run.
  • FIGS. 4A to 4F show three intensity distributions: the intensity distributions are represented as functions (two-dimensional model, upper representations) and as surfaces (rotationally symmetrical three-dimensional model, lower representations).
  • the axial length a was chosen according to a power of + 60D, the hyperopia relative to + 10D, the myopia -10D.
  • the figures show the following states (shown are the intensity distributions
  • Fig. 4A + 4B Hyperopia + 10D
  • Fig. 4C + 4D Emmetropia OD
  • Fig. 4E + 4F myopia -10D
  • FIG. 5 shows the intensity distribution IR &) of the radiation in the retina for myopia
  • FIG. 6 shows the intensity distribution IR 1 of the radiation in FIG
  • FIG. 7A shows three normalized intensity distributions for the myopia, normalized to 1.
  • Line A shows the nominal intensity distribution Is ⁇ ⁇ ) for the myopia
  • line C the absorption profile A (f) for the myopia.
  • Fig. 7B enlarged absorption profile ⁇ (v) for myopia (line C).
  • Fig. 8A shows three normalized intensity distributions for hyperopia normalized to 1.
  • Line A shows the desired intensity distribution Is ⁇ ⁇ ) for the hyperopia
  • line C the absorption profile A ( ⁇ ) for the hyperopia.
  • 8B enlarged absorption profile Mv) for hyperopia (line C).
  • the goal of physical modeling is to qualitatively calculate the intensity of the electromagnetic radiation in the retina that results when a constant and homogeneous intensity distribution of the radiation around the eye is imaged by the optical system onto the retina. As a standardized environment, the illumination of the background during the visual field examination in the perimeter should be used.
  • the perimeter P is represented by a semicircle with a radius p in the left half-plane, wherein the radius p is usually about 50 cm to 70 cm,
  • the retina R is represented by a semi-ellipse in the right half-plane with a variable semiaxis of the ellipse a in the direction of the positive x-axis,
  • a here is the surface of the retina and the differential and oriented surface element of the retina with normal vector Since we perform the differential-geometric description in two-dimensional space, the oriented and differential surface element corresponds to an oriented and differential line element so
  • the integral for the total intensity I R of the radiation in the retina can not be solved by means of tables or computer algebra systems in a closed form. However, this parameter integral can be numerically calculated point by point and thus represented as a function. If we also take the axis length of the eye a and the focal length of the optical system x f as parameters, the total retinal intensity is then a function in ⁇ of the form
  • IR IR ( ⁇ X f ⁇ ⁇ ) -
  • IR IR (V, *) -
  • X f a
  • the different local intensities of the radiation are detected in the area of the retina by the first neurons of the retina.
  • the cells of the retina have a mechanism with which they can detect the local intensity of the radiation (eg by measuring the number of photons).
  • the rods and cones of the retina recognize not only the local intensity of the radiation, but also the intensity of radiation in the adjacent retinal neurons (directly through cell-cell contacts or mediated by the retinal pigment epithelium, horizontal cells or Müller cells).
  • the retina is able to detect a global intensity distribution for the retina according to the modeled intensity distribution. According to the intensity distribution "measured" by the retina, factors for growth regulation are produced.
  • the ideal reference intensity distribution IB ⁇ is the intensity distribution at the emmetropia. If changes in the length of the eye a and changes in the refractive power x f of the eye occur, they cause an altered intensity distribution ⁇ %) •
  • Differential intensity AI ⁇ ⁇ ⁇ IU> ⁇ 1 ⁇ between the intensity distributions is measured and according to the sign of this difference intensity we postulate the expression of promoting and inhibiting factors that regulate the growth and power of the eye.
  • the goal of the treatment should be efficient growth support for insufficient or missing emmetropisation in severe hyperopia and, in order to avoid the progression of axial myopia, an efficient growth inhibition.
  • Myopia is seen to be unfavorable in the mechanisms of refractive correction
  • the optical filter should be an optical glass (eg spectacle lens), a contact lens or a
  • Be intraocular lens with a specific transmission gradient, such that in the retina around the macula at ⁇ Q radially symmetric target intensity distribution is produced.
  • This desired intensity distribution should correspond to the intensity distribution of the refractive uncorrected eye.
  • the transmission gradients apply to the model.
  • the model only spherical refractive errors were considered. If, in addition, there is astigmatism or a defective vision of a higher order, the corresponding spherical equivalent shall be converted.
  • the respective axial length and refractive power should also be used in order to then correspondingly transform the transmission profile to the given conditions.
  • the desired intensity distribution Is ⁇ for the myopia is the normalized myopic intensity distribution I M ( ⁇ ) (see FIG. 7),
  • the actual intensity distribution // ( ⁇ ) is the corresponding emmetropic intensity distribution for the myopia
  • the desired intensity distribution Is ⁇ is the hyperopie normalized to one hyperopic intensity distribution IH ⁇ (see Fig. 8),
  • the actual intensity distribution // ( ⁇ ) for the hyperopia is again the emmetropic intensity distribution IB ⁇ > related to the normalized desired function
  • the transmission coefficient T ( ⁇ ) is determined to be

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Prostheses (AREA)

Abstract

Élément optique, de préférence verre de lunettes, lentille de contact ou lentille intraoculaire, à utiliser pour corriger la myopie ou l'hyperopie. L'élément optique modifie la répartition d'intensité d'un rayonnement électromagnétique incident sur la rétine de l'œil d'un utilisateur. L'élément optique présente des régions ayant des degrés de transmission différents, qui modifient la répartition d'intensité du rayonnement électromagnétique incident sur la rétine de telle sorte qu'on peut obtenir une répartition d'intensité d'un oeil myope pour un oeil myope corrigé par réfraction, et une répartition d'intensité d'un oeil hyperope pour un oeil hyperope corrigé par réfraction.
PCT/AT2008/000002 2007-01-11 2008-01-07 Élément optique WO2008083418A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT602007 2007-01-11
ATA60/2007 2007-01-11

Publications (1)

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WO2008083418A1 true WO2008083418A1 (fr) 2008-07-17

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PCT/AT2008/000002 WO2008083418A1 (fr) 2007-01-11 2008-01-07 Élément optique

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WO (1) WO2008083418A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3298994A1 (fr) * 2008-12-22 2018-03-28 Medical College of Wisconsin, Inc. Procédé et appareil permettant de limiter la croissance de la longueur de l' il
US10571717B2 (en) 2016-08-01 2020-02-25 University Of Washington Ophthalmic lenses for treating myopia
US10884264B2 (en) 2018-01-30 2021-01-05 Sightglass Vision, Inc. Ophthalmic lenses with light scattering for treating myopia
US11718052B2 (en) 2017-05-08 2023-08-08 Sightglass Vision, Inc. Contact lenses for reducing myopia and methods for making the same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3636684A1 (de) * 1986-10-28 1988-05-11 Rodenstock Optik G Filter zur kompensation des helligkeitsabfalls in der bildebene eines objektives
WO2001082791A1 (fr) * 2000-04-28 2001-11-08 University Of Rochester Vision et imagerie retinienne ameliorees
WO2005055891A1 (fr) * 2003-11-19 2005-06-23 Vision Crc Limited Procedes et appareils pour modifier la courbure relative de champ et les positions de positions focales en dehors de l'axe, peripheriques

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3636684A1 (de) * 1986-10-28 1988-05-11 Rodenstock Optik G Filter zur kompensation des helligkeitsabfalls in der bildebene eines objektives
WO2001082791A1 (fr) * 2000-04-28 2001-11-08 University Of Rochester Vision et imagerie retinienne ameliorees
WO2005055891A1 (fr) * 2003-11-19 2005-06-23 Vision Crc Limited Procedes et appareils pour modifier la courbure relative de champ et les positions de positions focales en dehors de l'axe, peripheriques

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3298994A1 (fr) * 2008-12-22 2018-03-28 Medical College of Wisconsin, Inc. Procédé et appareil permettant de limiter la croissance de la longueur de l' il
EP3552587A1 (fr) * 2008-12-22 2019-10-16 Medical College of Wisconsin, Inc. Procédé et appareil permettant de limiter la croissance de la longueur de l'oeil
US10795181B2 (en) 2008-12-22 2020-10-06 The Medical College Of Wisconsin, Inc. Method and apparatus for limiting growth of eye length
US11048102B2 (en) 2008-12-22 2021-06-29 The Medical College Of Wisconsin, Inc. Method and apparatus for limiting growth of eye length
EP3973931A1 (fr) * 2008-12-22 2022-03-30 Medical College of Wisconsin, Inc. Procédé et appareil permettant de limiter la croissance de la longueur de l'oeil
US11493781B2 (en) 2008-12-22 2022-11-08 The Medical College Of Wisconsin, Inc. Method and apparatus for limiting growth of eye length
US10571717B2 (en) 2016-08-01 2020-02-25 University Of Washington Ophthalmic lenses for treating myopia
US11543681B2 (en) 2016-08-01 2023-01-03 University Of Washington Ophthalmic lenses for treating myopia
US11718052B2 (en) 2017-05-08 2023-08-08 Sightglass Vision, Inc. Contact lenses for reducing myopia and methods for making the same
US10884264B2 (en) 2018-01-30 2021-01-05 Sightglass Vision, Inc. Ophthalmic lenses with light scattering for treating myopia
US11914228B2 (en) 2018-01-30 2024-02-27 Sightglass Vision, Inc. Ophthalmic lenses with light scattering for treating myopia

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