WO2007104867A3 - Compositions cosmetiques, pharmaceutiques, alimentaires et veterinaires dont l'action d'activation des genes de type sirtuin permet de retarder le vieillissement des mammiferes et ses effets nefastes - Google Patents

Compositions cosmetiques, pharmaceutiques, alimentaires et veterinaires dont l'action d'activation des genes de type sirtuin permet de retarder le vieillissement des mammiferes et ses effets nefastes Download PDF

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Publication number
WO2007104867A3
WO2007104867A3 PCT/FR2007/000449 FR2007000449W WO2007104867A3 WO 2007104867 A3 WO2007104867 A3 WO 2007104867A3 FR 2007000449 W FR2007000449 W FR 2007000449W WO 2007104867 A3 WO2007104867 A3 WO 2007104867A3
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Prior art keywords
genes
cosmetic
pharmaceutical
food
ageing
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PCT/FR2007/000449
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English (en)
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WO2007104867A2 (fr
Inventor
Alain Fructus
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Af Consulting
Alain Fructus
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Publication of WO2007104867A2 publication Critical patent/WO2007104867A2/fr
Publication of WO2007104867A3 publication Critical patent/WO2007104867A3/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212—Face masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/046—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755—Gymnosperms [Coniferophyta]
    • A61K8/9761—Cupressaceae [Cypress family], e.g. juniper or cypress
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Compositions à usage cosmétique, pharmaceutique, alimentaire ou vétérinaire destinées à retarder le vieillissement des mammifères par leur action d'activation des gènes de type Sirtuin, gènes qui sont naturellement activées lors de restriction calorique. Ces compositions sont caractérisées en ce qu'elles contiennent un ou plusieurs oligomères de Resvératrol, et plus particulièrement l'ε-Viniférine, et/ou les glucosides et/ou les esters correspondants de ces oligomères et/ou les extraits naturels en contenant. Il a été montré sur plusieurs espèces vivantes que la restriction calorique allonge la durée de vie et diminue les effets délétères du vieillissement. Des études sur des primates et sur des populations humaines ont corroboré ces résultats. Il a également été montré que la restriction calorique active certains gènes appelés Sirtuins (silent information regulator). Dès lors, il a été recherché des ingrédients ou des molécules, naturels ou synthétiques qui activent des gènes et permettent de se passer d'une difficile restriction calorique à long terme. Le Resvératrol ou 3,4',5-trihydroxystilbène est connu pour activer certains gènes de la famille des Sirtuins. La présente invention décrit pour la première fois l'activation de ces gènes par les oligomères de Resvératrol, en particulier Pε-Viniférine. Un test spécifique a été réalisé et montre que Pε-Viniférine et un extrait de sarment de vigne en contenant ainsi que d'autres oligomères de Resvératrol, activent parfaitement l'enzyme SIRTl. Des compositions cosmétique, pharmaceutique, alimentaire et vétérinaire sont décrites à titre d'exemples. La composition cosmétique décrite et contenant un extrait de sarment de vigne a été soumise à des tests qui ont montré sa parfaite innocuité sur la peau humaine. Elle a de plus été soumise à un test sur humain montrant son efficacité à diminuer les effets du vieillissement. L'invention revendique des compositions cosmétiques, pharmaceutiques, alimentaires et vétérinaires dont l'action d'activation des gènes Sirtuins permet de retarder le vieillissement des mammifères et combattre ses effets néfastes.
PCT/FR2007/000449 2006-03-16 2007-03-15 Compositions cosmetiques, pharmaceutiques, alimentaires et veterinaires dont l'action d'activation des genes de type sirtuin permet de retarder le vieillissement des mammiferes et ses effets nefastes WO2007104867A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR06/02294 2006-03-16
FR0602294A FR2898493B1 (fr) 2006-03-16 2006-03-16 Compositions cosmetiques, pharmaceutiques, alimentaires et veterinaires dont l'action d'activation de genes de type sirtuin permet de retarder le vieillissement des mammiferes et ses effets nefastes

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Publication Number Publication Date
WO2007104867A2 WO2007104867A2 (fr) 2007-09-20
WO2007104867A3 true WO2007104867A3 (fr) 2007-11-15

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PCT/FR2007/000449 WO2007104867A2 (fr) 2006-03-16 2007-03-15 Compositions cosmetiques, pharmaceutiques, alimentaires et veterinaires dont l'action d'activation des genes de type sirtuin permet de retarder le vieillissement des mammiferes et ses effets nefastes

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FR (1) FR2898493B1 (fr)
WO (1) WO2007104867A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102300578A (zh) * 2008-12-01 2011-12-28 延寿有限责任公司 用于改变健康、安康和寿命的方法和组合物

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AU2005207029B2 (en) 2004-01-20 2011-09-01 Brigham Young University Novel sirtuin activating compounds and methods for making the same
EP2005941A3 (fr) * 2007-06-01 2009-04-01 Henkel AG & Co. KGaA Compositions rajeunissant les cellules
US8703161B2 (en) 2007-08-13 2014-04-22 Elc Management, Llc Skin repair compositions comprising circadian gene activators and a synergistic combination of Sirt1 gene activators
US20090047309A1 (en) * 2007-08-13 2009-02-19 Maes Daniel H Cosmetic methods and compositions for repairing human skin
US8193155B2 (en) 2009-02-09 2012-06-05 Elc Management, Llc Method and compositions for treating skin
JP2009249320A (ja) * 2008-04-04 2009-10-29 Hosoda Shc:Kk 肥満・糖尿病改善剤
JP2010030911A (ja) * 2008-07-25 2010-02-12 Morinaga & Co Ltd コラーゲン産生促進剤
FR2938769B1 (fr) * 2008-11-26 2010-12-31 Isp Investments Inc Composition cosmetique et/ou pharmaceutique comprenant un hydrolysat de feuille de vigne (vitis viniferal.)en tant que principe actif activateur du cytochrome c
FR2938766B1 (fr) * 2008-11-26 2010-12-31 Isp Investments Inc Composition cosmetique et/ou pharmaceutique comprenant un hydrolysat de feuille de vigne (vitis vinifera l.) en tant que principe actif activateur de l'aconitase et protecteur des mitochondries
FR2938765B1 (fr) * 2008-11-26 2010-12-31 Isp Investments Inc Composition cosmetique et/ou pharmaceutique comprenant un hydrolysat de feuille de vigne (vitis vinifera l.) en tant que principe actif activateur des proteines sirt
JP2010184886A (ja) * 2009-02-12 2010-08-26 Hosoda Shc:Kk 新規化合物
JP2011105624A (ja) * 2009-11-13 2011-06-02 Nof Corp 表皮角化細胞賦活剤および皮膚外用剤
JP5967858B2 (ja) * 2009-11-13 2016-08-10 日油株式会社 ヒアルロニダーゼ活性阻害剤
WO2011079212A2 (fr) * 2009-12-24 2011-06-30 LifeSpan Extension, LLC Procédés et compositions destinés à identifier, produire et utiliser des produits dérivés de plantes pour modulation de la fonction cellulaire et du vieillissement
FR2966040A1 (fr) 2010-10-19 2012-04-20 Brigitte Gourlaouen Composition amincissante et/ou de prevention des processus inflammatoires
ITTV20110090A1 (it) * 2011-06-30 2012-12-31 Mac Pharma My Cli Srl Composizione per il trattamento topico dell'aging cutaneo di viso e corpo e degli inestetismi cutanei della cellulite
JP5892436B2 (ja) * 2011-08-26 2016-03-23 ビーエイチエヌ株式会社 血圧降下剤
US10383815B2 (en) 2012-09-14 2019-08-20 Elc Management Llc Method and compositions for improving selective catabolysis in cells of keratin surfaces
JP5859587B2 (ja) * 2014-03-03 2016-02-10 日油株式会社 皮膚外用剤
CN105055994A (zh) * 2015-08-07 2015-11-18 成都市飞龙水处理技术研究所 一种治疗阑尾脓肿的内服药物及其制备方法
CN105055993A (zh) * 2015-08-07 2015-11-18 成都市飞龙水处理技术研究所 一种治疗阑尾周围脓肿的汤剂药物及其制备方法
US10456343B2 (en) 2017-01-26 2019-10-29 L'oreal Microemulsion compositions comprising polydatin and method of use

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WO2000021526A1 (fr) * 1998-10-09 2000-04-20 Sigma-Tau Healthscience S.P.A. Combinaison de carnitines et de resveratrol pour prevenir ou traiter les troubles cerebraux ou du vieillissement
WO2000038620A2 (fr) * 1998-12-24 2000-07-06 1333366 Ontario Inc. Composition utile pour traiter la parodontopathie
WO2002032410A2 (fr) * 2000-10-19 2002-04-25 Imperial College Innovations Limited Administration de resveratrol pour traiter des pathologies respiratoires inflammatoires
FR2816843A1 (fr) * 2000-11-23 2002-05-24 Actichem Inhibiteurs de l'enzyme 5 alpha-reductase
WO2003103583A2 (fr) * 2002-06-10 2003-12-18 Oklahoma Medical Research Foundation Procede d'utilisation de bis(polyhydroxyphenyles) et de derives o-alkyle correspondants, fixes, pour le traitement de maladies inflammatoires du systeme nerveux central
WO2004026222A2 (fr) * 2002-09-20 2004-04-01 Af Consulting COMPOSITIONS POUR LES SOINS DE LA PEAU SUBISSANT UN DÉSÉQUILIBRE HORMONAL, ET CONTENANT UN OU DES OLIGOMÈRES DE RESVÉRATROL, EN PARTICULIER DE L'ϵ-VINIFÉRINE, ET/OU CERTAINS DE LEURS DÉRIVÉS.
WO2005004630A1 (fr) * 2003-07-09 2005-01-20 Giuliani S.P.A. Composition a activite antioxydante et a usage pharmaceutique, dietetique ou cosmetique

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000021526A1 (fr) * 1998-10-09 2000-04-20 Sigma-Tau Healthscience S.P.A. Combinaison de carnitines et de resveratrol pour prevenir ou traiter les troubles cerebraux ou du vieillissement
WO2000038620A2 (fr) * 1998-12-24 2000-07-06 1333366 Ontario Inc. Composition utile pour traiter la parodontopathie
WO2002032410A2 (fr) * 2000-10-19 2002-04-25 Imperial College Innovations Limited Administration de resveratrol pour traiter des pathologies respiratoires inflammatoires
FR2816843A1 (fr) * 2000-11-23 2002-05-24 Actichem Inhibiteurs de l'enzyme 5 alpha-reductase
WO2003103583A2 (fr) * 2002-06-10 2003-12-18 Oklahoma Medical Research Foundation Procede d'utilisation de bis(polyhydroxyphenyles) et de derives o-alkyle correspondants, fixes, pour le traitement de maladies inflammatoires du systeme nerveux central
WO2004026222A2 (fr) * 2002-09-20 2004-04-01 Af Consulting COMPOSITIONS POUR LES SOINS DE LA PEAU SUBISSANT UN DÉSÉQUILIBRE HORMONAL, ET CONTENANT UN OU DES OLIGOMÈRES DE RESVÉRATROL, EN PARTICULIER DE L'ϵ-VINIFÉRINE, ET/OU CERTAINS DE LEURS DÉRIVÉS.
WO2005004630A1 (fr) * 2003-07-09 2005-01-20 Giuliani S.P.A. Composition a activite antioxydante et a usage pharmaceutique, dietetique ou cosmetique

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102300578A (zh) * 2008-12-01 2011-12-28 延寿有限责任公司 用于改变健康、安康和寿命的方法和组合物

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FR2898493B1 (fr) 2008-08-08
WO2007104867A2 (fr) 2007-09-20

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