WO2007006548A3 - Antibakterielle amid-makrozyklen vii - Google Patents

Antibakterielle amid-makrozyklen vii Download PDF

Info

Publication number
WO2007006548A3
WO2007006548A3 PCT/EP2006/006770 EP2006006770W WO2007006548A3 WO 2007006548 A3 WO2007006548 A3 WO 2007006548A3 EP 2006006770 W EP2006006770 W EP 2006006770W WO 2007006548 A3 WO2007006548 A3 WO 2007006548A3
Authority
WO
WIPO (PCT)
Prior art keywords
vii
antibacterial amide
amide macrocycles
macrocycles
antibacterial
Prior art date
Application number
PCT/EP2006/006770
Other languages
English (en)
French (fr)
Other versions
WO2007006548A2 (de
Inventor
Rainer Endermann
Kerstin Ehlert
Martin Michels
Stefan Weigand
Guido Schiffer
Original Assignee
Aicuris Gmbh & Co Kg
Rainer Endermann
Kerstin Ehlert
Martin Michels
Stefan Weigand
Guido Schiffer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aicuris Gmbh & Co Kg, Rainer Endermann, Kerstin Ehlert, Martin Michels, Stefan Weigand, Guido Schiffer filed Critical Aicuris Gmbh & Co Kg
Priority to JP2008520778A priority Critical patent/JP2009501173A/ja
Priority to EP06762521A priority patent/EP1907413A2/de
Publication of WO2007006548A2 publication Critical patent/WO2007006548A2/de
Publication of WO2007006548A3 publication Critical patent/WO2007006548A3/de
Priority to US12/008,662 priority patent/US20080306040A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Die Erfindung betrifft antibakterielle Amid-Makrozyklen und Verfahren zu ihrer Herstellung, ihre Verwendung zur Behandlung und/oder Prophylaxe von Krankheiten sowie ihre Verwendung zur Herstellung von Arzneimitteln zur Behandlung und/oder Prophylaxe von Krankheiten, insbesondere von bakteriellen Infektionen.
PCT/EP2006/006770 2005-07-14 2006-07-11 Antibakterielle amid-makrozyklen vii WO2007006548A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2008520778A JP2009501173A (ja) 2005-07-14 2006-07-11 抗菌性アミドマクロサイクルｖｉｉ
EP06762521A EP1907413A2 (de) 2005-07-14 2006-07-11 Antibakterielle amid-makrozyklen vii
US12/008,662 US20080306040A1 (en) 2005-07-14 2008-01-11 Antibacterial amide macrocycles VII

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005032781A DE102005032781A1 (de) 2005-07-14 2005-07-14 Antibakterielle Amid-Markozyklen VII
DE102005032781.8 2005-07-14

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/008,662 Continuation US20080306040A1 (en) 2005-07-14 2008-01-11 Antibacterial amide macrocycles VII

Publications (2)

Publication Number Publication Date
WO2007006548A2 WO2007006548A2 (de) 2007-01-18
WO2007006548A3 true WO2007006548A3 (de) 2007-03-22

Family

ID=37507564

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/006770 WO2007006548A2 (de) 2005-07-14 2006-07-11 Antibakterielle amid-makrozyklen vii

Country Status (5)

Country Link
US (1) US20080306040A1 (de)
EP (1) EP1907413A2 (de)
JP (1) JP2009501173A (de)
DE (1) DE102005032781A1 (de)
WO (1) WO2007006548A2 (de)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003106480A1 (de) * 2002-06-17 2003-12-24 Bayer Healthcare Ag Antibakterielle amid-makrozyklen
WO2004012816A1 (de) * 2002-07-29 2004-02-12 Bayer Healthcare Ag Antibakterielle ester-makrozyklen
WO2005033129A1 (de) * 2003-10-01 2005-04-14 Bayer Healthcare Ag Antibakterielle amid-makrozyklen
WO2005058943A1 (de) * 2003-12-16 2005-06-30 Aicuris Gmbh & Co. Kg Antibakterielle makrozyklen mit substituiertem biphenyl
WO2005100380A1 (de) * 2004-04-16 2005-10-27 Aicuris Gmbh & Co.Kg Antibakterielle amid-makrozyklen ii
WO2005118613A2 (de) * 2004-05-26 2005-12-15 Aicuris Gmbh & Co.Kg Antibakterielle amid-makrozyklen
WO2006034786A1 (de) * 2004-09-24 2006-04-06 Aicuris Gmbh & Co.Kg Antibakterielle amid-makrozyklen iv
WO2006103015A1 (de) * 2005-03-30 2006-10-05 Aicuris Gmbh & Co. Kg Antibakterielle amid-makrozyklen v
WO2006103009A1 (de) * 2005-03-30 2006-10-05 Aicuris Gmbh & Co. Kg Antibakterielle amid-makrozyklen vi

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2720066B1 (fr) * 1994-05-20 1996-06-28 Rhone Poulenc Rorer Sa Peptides antagonistes de la neurotensine.

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003106480A1 (de) * 2002-06-17 2003-12-24 Bayer Healthcare Ag Antibakterielle amid-makrozyklen
WO2004012816A1 (de) * 2002-07-29 2004-02-12 Bayer Healthcare Ag Antibakterielle ester-makrozyklen
WO2005033129A1 (de) * 2003-10-01 2005-04-14 Bayer Healthcare Ag Antibakterielle amid-makrozyklen
WO2005058943A1 (de) * 2003-12-16 2005-06-30 Aicuris Gmbh & Co. Kg Antibakterielle makrozyklen mit substituiertem biphenyl
WO2005100380A1 (de) * 2004-04-16 2005-10-27 Aicuris Gmbh & Co.Kg Antibakterielle amid-makrozyklen ii
WO2005118613A2 (de) * 2004-05-26 2005-12-15 Aicuris Gmbh & Co.Kg Antibakterielle amid-makrozyklen
WO2006034786A1 (de) * 2004-09-24 2006-04-06 Aicuris Gmbh & Co.Kg Antibakterielle amid-makrozyklen iv
WO2006103015A1 (de) * 2005-03-30 2006-10-05 Aicuris Gmbh & Co. Kg Antibakterielle amid-makrozyklen v
WO2006103009A1 (de) * 2005-03-30 2006-10-05 Aicuris Gmbh & Co. Kg Antibakterielle amid-makrozyklen vi

Also Published As

Publication number Publication date
JP2009501173A (ja) 2009-01-15
WO2007006548A2 (de) 2007-01-18
US20080306040A1 (en) 2008-12-11
DE102005032781A1 (de) 2007-01-18
EP1907413A2 (de) 2008-04-09
DE102005032781A8 (de) 2008-06-26

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