WO2006024392A3 - Aufnahmeeinheit für biologische objekte sowie verfahren und vorrichtung zur verarbeitung in der aufnahmeeinheit aufgenommener biologischer objekte - Google Patents

Aufnahmeeinheit für biologische objekte sowie verfahren und vorrichtung zur verarbeitung in der aufnahmeeinheit aufgenommener biologischer objekte Download PDF

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Publication number
WO2006024392A3
WO2006024392A3 PCT/EP2005/008890 EP2005008890W WO2006024392A3 WO 2006024392 A3 WO2006024392 A3 WO 2006024392A3 EP 2005008890 W EP2005008890 W EP 2005008890W WO 2006024392 A3 WO2006024392 A3 WO 2006024392A3
Authority
WO
WIPO (PCT)
Prior art keywords
biological objects
receiving unit
treating
openings
plate
Prior art date
Application number
PCT/EP2005/008890
Other languages
English (en)
French (fr)
Other versions
WO2006024392A2 (de
Inventor
Karin Schuetze
Yilmaz Niyaz
Raimund Schuetze
Original Assignee
Palm Microlaser Tech Gmbh
Karin Schuetze
Yilmaz Niyaz
Raimund Schuetze
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palm Microlaser Tech Gmbh, Karin Schuetze, Yilmaz Niyaz, Raimund Schuetze filed Critical Palm Microlaser Tech Gmbh
Priority to EP05774733A priority Critical patent/EP1805495A2/de
Publication of WO2006024392A2 publication Critical patent/WO2006024392A2/de
Publication of WO2006024392A3 publication Critical patent/WO2006024392A3/de

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50857—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using arrays or bundles of open capillaries for holding samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0454—Moving fluids with specific forces or mechanical means specific forces radiation pressure, optical tweezers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873—Cutting or cleaving
    • G01N2001/2886—Laser cutting, e.g. tissue catapult

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Es wird eine Aufnahmeeinheit für biologische Objekte bereitgestellt, welche ein plattenförmiges Element (1) mit einer Vielzahl von Öffnungen (2) umfasst. Diese Öffnungen sind insbesondere entsprechend den Öffnungen (10a) einer Mikrotiter- oder Multiwellplatte (10) angeordnet. Hierdurch ist ein einfaches Einbringen von biologischen Objekten (5) beispielsweise mittels Laser-Catapulting in das Aufnahmeelement und von dort in die Mikrotiter- oder Multiwellplatte möglich. Zudem wird eine Vorrichtung zur Wärmebehandlung von in der Aufnahmeeinheit befindlichen biologischen Objekten bereitgestellt.
PCT/EP2005/008890 2004-08-30 2005-08-16 Aufnahmeeinheit für biologische objekte sowie verfahren und vorrichtung zur verarbeitung in der aufnahmeeinheit aufgenommener biologischer objekte WO2006024392A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP05774733A EP1805495A2 (de) 2004-08-30 2005-08-16 Aufnahmeeinheit f]r biologische objekte sowie verfahren und vorrichtung zur verarbeitung in der aufnahmeeinheit aufgenommener biologischer objekte

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004041941.8 2004-08-30
DE200410041941 DE102004041941B4 (de) 2004-08-30 2004-08-30 Verfahren zur Gewinnung von biologischen Objekten mit einer Aufnahmeeinheit

Publications (2)

Publication Number Publication Date
WO2006024392A2 WO2006024392A2 (de) 2006-03-09
WO2006024392A3 true WO2006024392A3 (de) 2006-06-01

Family

ID=35295412

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/008890 WO2006024392A2 (de) 2004-08-30 2005-08-16 Aufnahmeeinheit für biologische objekte sowie verfahren und vorrichtung zur verarbeitung in der aufnahmeeinheit aufgenommener biologischer objekte

Country Status (3)

Country Link
EP (1) EP1805495A2 (de)
DE (1) DE102004041941B4 (de)
WO (1) WO2006024392A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9329194B2 (en) 2007-11-05 2016-05-03 Abbott Laboratories Automated analyzer for clinical laboratory

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DE102005026540A1 (de) * 2005-06-08 2006-12-14 P.A.L.M. Microlaser Technologies Ag Verfahren und Vorrichtung zur Handhabung von Objekten
US7807108B2 (en) 2006-09-18 2010-10-05 Leica Microsystems Cms Gmbh Apparatus for receiving biological specimens
EP2251668B1 (de) 2009-05-13 2018-12-05 ibidi GmbH Verfahren zum Positionieren einer organischen, biologischen und/oder medizinischen Probe
DE102013212811A1 (de) * 2013-07-01 2015-01-08 Leica Microsystems Cms Gmbh Lasermikrodissektionssystem und Untersuchungsverfahren für nukleinsäurehaltige Proben
US11719702B2 (en) 2016-11-07 2023-08-08 Battelle Memorial Institute Methods and systems of proteome analysis and imaging
EP3535418B1 (de) 2016-11-07 2021-12-15 Battelle Memorial Institute Nanoskalige biochemische probenvorbereitung und analyse
CN107589105B (zh) * 2017-07-21 2021-08-24 中国科学院青岛生物能源与过程研究所 一种用于单细胞快速拉曼测量和激光弹射分选的一体化装置

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WO2002066550A1 (en) * 2001-02-20 2002-08-29 The United States Of America, As Represented By The Secretary Of The Navy Naval Research Laboratory Generation of biomaterial microarrays by laser transfer
WO2002087760A1 (de) * 2001-04-30 2002-11-07 Epr Labautomation Ag Verfahren und anordnung zur speicherung und dosierung von kleinen flüssigkeitsmengen

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US6387331B1 (en) * 1998-01-12 2002-05-14 Massachusetts Institute Of Technology Method and apparatus for performing microassays
US20020094533A1 (en) * 2000-10-10 2002-07-18 Hess Robert A. Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof
WO2002066550A1 (en) * 2001-02-20 2002-08-29 The United States Of America, As Represented By The Secretary Of The Navy Naval Research Laboratory Generation of biomaterial microarrays by laser transfer
WO2002087760A1 (de) * 2001-04-30 2002-11-07 Epr Labautomation Ag Verfahren und anordnung zur speicherung und dosierung von kleinen flüssigkeitsmengen

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9329194B2 (en) 2007-11-05 2016-05-03 Abbott Laboratories Automated analyzer for clinical laboratory

Also Published As

Publication number Publication date
DE102004041941A1 (de) 2006-03-02
WO2006024392A2 (de) 2006-03-09
EP1805495A2 (de) 2007-07-11
DE102004041941B4 (de) 2007-01-11

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