WO2005023108A1 - 磁気共鳴イメージング装置 - Google Patents
磁気共鳴イメージング装置 Download PDFInfo
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- WO2005023108A1 WO2005023108A1 PCT/JP2004/012835 JP2004012835W WO2005023108A1 WO 2005023108 A1 WO2005023108 A1 WO 2005023108A1 JP 2004012835 W JP2004012835 W JP 2004012835W WO 2005023108 A1 WO2005023108 A1 WO 2005023108A1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/4818—MR characterised by data acquisition along a specific k-space trajectory or by the temporal order of k-space coverage, e.g. centric or segmented coverage of k-space
- G01R33/4824—MR characterised by data acquisition along a specific k-space trajectory or by the temporal order of k-space coverage, e.g. centric or segmented coverage of k-space using a non-Cartesian trajectory
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/565—Correction of image distortions, e.g. due to magnetic field inhomogeneities
- G01R33/56509—Correction of image distortions, e.g. due to magnetic field inhomogeneities due to motion, displacement or flow, e.g. gradient moment nulling
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/567—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution gated by physiological signals, i.e. synchronization of acquired MR data with periodical motion of an object of interest, e.g. monitoring or triggering system for cardiac or respiratory gating
- G01R33/5676—Gating or triggering based on an MR signal, e.g. involving one or more navigator echoes for motion monitoring and correction
Definitions
- the present invention relates to a magnetic resonance imaging apparatus that obtains a tomographic image of an examination region of a subject by using a nuclear magnetic resonance phenomenon, and in particular, reduces image artifacts caused by body movement of the subject by signal correction.
- a magnetic resonance imaging apparatus that obtains a tomographic image of an examination region of a subject by using a nuclear magnetic resonance phenomenon, and in particular, reduces image artifacts caused by body movement of the subject by signal correction.
- MRI apparatus magnetic resonance imaging apparatus
- body motion artifact occurs. This is because, as shown in Fig. 1 (a), when sampling the echo signal of each grid point in k-space, sampling parallel to the frequency encoding direction is repeated in the phase encoding direction (hereinafter referred to as “Cartesian system”). Sampling method "!!
- a method of correcting a displacement due to body movement there is generally a method of calculating and correcting the amount of movement of a subject based on a correlation (hereinafter, referred to as a correlation method). It is disclosed in conv.
- Non-Patent Document 1 Takizawa et. Al., Nuclear magnetic resonance imaging method and device, USP 6,541,970
- Non-Patent Document 2 discloses a hybrid radial method (FIG. 1 (c)) in which all measurements are divided into a plurality of blocks, and each block is measured at a different k-space rotation angle. It describes that body movements due to rotational movement and parallel movement are corrected using a correlation method or a method similar to the correlation method, respectively. However, even in the case of correcting only rotational movement, it is necessary to repeat the process of creating a rotated image (gritting) and the correlation calculation with the number of repetitions (for example, 100 times) determined by the detection accuracy. Processing speed is very slow. If an attempt is made to increase the detection accuracy, the processing speed further decreases. This problem is the same in the radial method for measuring the k-space radially (FIG. 1 (b)).
- Non-Patent Document 2 James G. Pipe, Motion Correction With PROPELLER MRI:
- an object of the present invention is to correct a body motion caused by rotation and translation of a subject with high speed and high accuracy in a hybrid radial method or a radial sampling method.
- the present invention is configured as follows.
- a body motion correcting step for correcting body motion in other unit k-space data (f) repeating the body movement correction step (e), a body movement correction repeating step of performing the body movement correction for all the other unit k-space data,
- Magnetic resonance imaging methods including:
- the body motion correcting step (e) includes extracting at least a part of data in the low spatial frequency region of the reference unit k-space data and the other unit k-space data to determine a mutual phase difference, The body movement is detected.
- the phase difference of a part of the extracted data and the amount of body movement are detected, so that the repetitive processing by the correlation method is not required, and the amount of calculation required for body movement correction is Can be reduced, and body movement correction can be performed at high speed and with high accuracy.
- the amount of body motion of the subject can be calculated and corrected for each component of rotation and parallel movement in the measurement space, so that highly accurate body motion correction can be performed.
- the first data array at least a part of data on a circumference of a predetermined radius surrounding the origin of the k-space is used.
- the rotating and moving component detecting step is performed after Fourier transform of the first data array. A phase difference is obtained, and a primary change force of the phase difference is detected as the rotational movement component.
- a rotational movement in the same direction as the rotational movement component detected for the unit k-space data and in the opposite direction is added to the unit k-space data to be corrected for body motion.
- the second data array is data on a line segment passing through the origin in the low spatial frequency region
- a phase difference is obtained from the second data array, and a translation component in the direction of the line segment is detected from a primary linear curve fitted to the phase difference.
- the second data array is data of an area including the origin in the low spatial frequency area
- the translation component detection step G) determines a phase difference from the second data array, and detects a translation component from a primary plane fitted to the phase difference.
- the translation component correcting step (k) gives a phase rotation to the unit k-space data to be corrected for body motion so that the translation component detected by the unit k-space data is canceled. .
- the rearrangement step (c) is performed simultaneously with the rotational movement correction in the rotational movement component correction step (i).
- the rearrangement step can be omitted, and the amount of calculation for image reconstruction can be reduced.
- the reference selecting step (d) is performed before the body motion correcting step (e), and the body motion correcting repeating step (f) is omitted.
- the body movement correction step (e) is performed between the unit measurement step (a) and the unit measurement repetition step (b), and detects at least the body movement in accordance with the detected body movement amount. Correcting the unit k space data and changing the measurement conditions of the unit measurement step (a) to be performed next in the unit measurement repetition step (b),
- the unit measurement repeating step (b) measures the echo signal by performing the unit measurement step (a) under the changed measurement conditions.
- the measurement conditions in the subsequent unit measurement step are changed in accordance with the detected amount of body movement, so that an image in which body movement artifacts are further suppressed can be formed.
- the body movement correction step (e) changes an angle of a measurement trajectory with respect to a coordinate axis of the k space in the unit measurement step according to the detected rotational movement component of the body movement amount.
- the body movement amount correcting step (e) changes at least one of the reception frequency and the reception phase of the echo signal in the unit measurement step according to the detected parallel movement component of the body movement amount.
- the body movement amount correcting step (e) corrects the unit k-space data in which the body movement amount is detected based on the detected body movement amount.
- the unit measurement step measures k-space data of a unit region having a predetermined width from a low spatial frequency region to a high spatial frequency region of the k space and also including a plurality of parallel measurement trajectory forces. I do.
- the unit measurement step measures k-space data on a plurality of radial straight lines passing through the origin.
- a static magnetic field generating means for applying a static magnetic field to the subject Gradient magnetic field generating means for applying a gradient magnetic field,
- High-frequency magnetic field generating means for irradiating a high-frequency magnetic field pulse for inducing nuclear magnetic resonance to nuclear spins in the subject
- Echo signal receiving means for detecting an echo signal emitted by nuclear magnetic resonance; image reconstructing means for performing an operation for reconstructing an image using the echo signal; and k space in which data of the echo signal is arranged.
- the gradient magnetic field generating means and the high-frequency magnetic field generating means such that the measurement is performed by dividing the block into a plurality of blocks having a measurement trajectory passing through the origin and having different angles of the measurement trajectory with respect to the coordinate axis of the k space.
- measurement control means for controlling the echo signal receiving means,
- the body motion correcting unit extracts at least a part of data of a low-frequency measurement region in the reference block and the other block, and calculates a phase difference therebetween. And the phase difference force is detected.
- the body movement correction means detects a rotation movement component of the body movement amount and corrects the rotation movement component, and detects a translation movement component of the body movement amount and corrects the parallel movement component. And a translation component correcting means.
- the rotational movement component correction means adds a rotational movement in the opposite direction to the data of the block to be corrected for body motion, the amount being the same as the rotational movement component detected for the data of the block.
- the translation component correcting means applies a phase rotation to the data of the block to be corrected for body motion so that the translation component detected for the data of the block is canceled.
- the body movement correction unit changes a measurement condition of the echo signal according to the body movement amount
- the measurement control unit measures the echo signal under the changed measurement condition.
- FIG. 2 is a block diagram showing the overall configuration of the MRI apparatus according to the present invention.
- This MRI apparatus uses a nuclear magnetic resonance (NMR) phenomenon to obtain a tomographic image of a subject, and as shown in FIG. 2, a static magnetic field generation system 2, a gradient magnetic field generation system 3, and a transmission system 5 , A reception system 6, a signal processing system 7, a sequencer 4, and a central processing unit (CPU) 8.
- NMR nuclear magnetic resonance
- the static magnetic field generation system 2 generates a uniform static magnetic field in the space around the subject 1 in the body axis direction or in a direction orthogonal to the body axis. Or, a normal or superconducting magnetic field generating means is provided!
- the gradient magnetic field generating system 3 includes a gradient magnetic field coil 9 wound in three directions of X, ⁇ , and Z, and a gradient magnetic field power supply 10 for driving each gradient magnetic field coil.
- the gradient magnetic fields Gs, Gp, and Gl in the desired three directions orthogonal to each other are applied to the subject 1.
- X, ⁇ , Z! The slice direction gradient pulse (Gs) is applied in one direction to set the slice plane for the subject 1, and the phase encode direction gradient magnetic field pulse (Gp) and frequency encode direction gradient are applied in the other two directions.
- a magnetic field pulse (Gf) is applied to encode the position information in each direction into the echo signal.
- the sequencer 4 is a control means for repeatedly applying a high-frequency magnetic field pulse (hereinafter, referred to as “RF pulse”) and a gradient magnetic field pulse in a predetermined pulse sequence.
- RF pulse high-frequency magnetic field pulse
- the sequencer 4 operates under the control of the CPU 8, and operates under the control of the CPU 8.
- Various commands necessary for image data collection are sent to the transmission system 5, the gradient magnetic field generation system 3, and the reception system 6.
- the transmission system 5 irradiates an RF pulse to cause nuclear spins of atoms constituting the living tissue of the subject 1 to cause nuclear magnetic resonance.
- the transmission system 5 includes a high-frequency oscillator 11, a modulator 12, a high-frequency amplifier 13, A power is also generated with the high-frequency coil 14a on the transmitting side.
- the high-frequency pulse output from the high-frequency oscillator 11 is amplitude-modulated by the modulator 12 at a timing specified by a command from the sequencer 4, and the amplitude-modulated high-frequency pulse is amplified by the high-frequency amplifier 13 and placed close to the subject 1.
- the test object 1 is irradiated with an electromagnetic wave (RF pulse) by supplying it to the high-frequency coil 14a.
- RF pulse electromagnetic wave
- the receiving system 6 detects an echo signal (NMR signal) emitted by nuclear magnetic resonance of nuclear spins constituting the living tissue of the subject 1, and includes a high-frequency coil 14b on the receiving side, an amplifier 15 and It comprises a quadrature phase detector 16 and an AZD converter 17.
- the electromagnetic wave (MR signal) of the response of the subject 1 induced by the electromagnetic wave emitted from the high-frequency coil 14a on the transmitting side is detected by the high-frequency coil 14b arranged close to the subject 1, and amplified by the amplifier 15. Thereafter, the signal is divided into two orthogonal signals by the quadrature phase detector 16 at a timing according to a command from the sequencer 4, and each signal is converted into a digital quantity by the AZD transformer 17 and sent to the signal processing system 7.
- the signal processing system 7 has an external storage device such as an optical disk 19 and a magnetic disk 18 and a display 20 formed of a CRT or the like.
- an external storage device such as an optical disk 19 and a magnetic disk 18 and a display 20 formed of a CRT or the like.
- the CPU 8 Processing such as signal processing and image reconstruction is executed, and the resulting tomographic image of the subject 1 is displayed on the display 20 and recorded on the magnetic disk 18 of an external storage device.
- the high-frequency coils 14 a and 14 b on the transmission side and the reception side and the gradient coil 9 are installed in the static magnetic field space of the static magnetic field generation system 2 arranged in the space around the subject 1. It has been.
- the spin species to be imaged by the MRI apparatus are protons, which are the main constituent substances of the subject, as being widely used in clinical practice.
- protons which are the main constituent substances of the subject, as being widely used in clinical practice.
- k-space is divided into a plurality of blocks (unit areas), each block is measured at a different k-space rotation angle, and phase encoding is performed on the echo signal measured within the block.
- Figure 3 shows the Daradent echo pulse sequence using the hybrid radial method.
- RF, Gs, Gp, Gr, A / D, and echo are RF pulse, gradient magnetic field in the first direction (slice), gradient magnetic field in the second direction, gradient magnetic field in the third direction, and AZD, respectively.
- RF, Gs, Gp, Gr, A / D, and echo are RF pulse, gradient magnetic field in the first direction (slice), gradient magnetic field in the second direction, gradient magnetic field in the third direction, and AZD, respectively.
- AZD gradient magnetic field in the third direction
- 301 is an RF pulse
- 302 is a slice selection gradient magnetic field pulse
- 303 and 304 are frequency encoding pulse regions
- 305 and 306 are phase encoding pulse regions
- 307 is a sampling window
- 3081-3084 is one echo signal
- 309 is a repetition.
- the pulse sequence shown in Fig. 3 exemplifies a case in which the measurement 310 is divided into four blocks (also referred to as blades) 309-1-1 309-4, and five echo signals are acquired in each block. ing.
- Gradient magnetic field output is set so that each block 309—1 309—4 has a different rotation angle on k-space, and a phase encode pulse is added in each block 309—1—1 309—4.
- the outputs of the gradient magnetic fields 303 and 304 are configured to change in accordance with the rotation angle, and a phase encoding amount is added by the gradient magnetic fields 305 and 306 applied before that.
- the process proceeds to the second block 309—2 and performs phase encoding.
- Five different echo signals 3082-1 and 3082-5 with different quantities 305-2 and 306-2 are acquired. This operation is similarly performed for the third block 309-3 and the fourth block 309-4 to obtain the echo signals 3083-1 to 3083-5 and 3084-1 to 3084-5, and to perform image reconstruction. Obtain all necessary echo signals.
- the sequence is executed so that block 309-1 is parallel to the Kx axis, and block 309-3 is parallel to the Ky axis.
- the gradient magnetic fields 306-1 and 305-3 do not include a phase encoding component, and their outputs are constant.
- Fig. 1 (c) The result of arranging the echo signals thus obtained in the k-space is as shown in Fig. 1 (c).
- data 401-1-401-4 consisting of five echo signals rotating at an angle ⁇ and having different phase encoding amounts are obtained for each block 309-1 309-4.
- the gridding process is a process of relocating the data obtained by non-orthogonal sampling to the coordinates of grid points in k-space. That is, the k-space 400 has regular grid point coordinates as shown by the black circles in FIG. However, since data obtained by non-orthogonal sampling, for example, data 401-2, passes through different trajectories (coordinates) with respect to the k space, the sampled data indicated by white circles does not match the grid point coordinates of the k space. In the gridding process, the sampled data (white circles in the figure) are used to rearrange the data at regular grid point coordinates (black circles in the figure) by interpolation.
- the gridding process is introduced in, for example, JI Jackson et.al., selection of a Convolution Function for Fourier Inversion Using Gndding, IEEE Trans.Med.Imaging, Vol. 10, PP. 473-478, 1991. It can be performed using interpolation functions such as sine function and Kaiser-Bessel function.
- FIG. 5 schematically shows the correction procedure.
- the body motion compensation is composed of a rotation compensation 501 (steps 503-506) and a translation compensation 502 (steps 507-509).
- a rotation compensation 501 steps 503-506
- a translation compensation 502 steps 507-509.
- one of the plurality of blocks is used as a reference block, and the data of the reference block is used.
- the rotation correction is performed on the data of the other blocks corresponding to, and then the translation correction is performed on the data corrected for rotation in.
- a data array for detecting the amount of body movement rotation generated during the measurement of each block is created (Step 503).
- the data array is created by extracting data reflecting body movement (rotation) from the area (common area) where the data of each block overlaps.
- data on a circumference having a predetermined radius R centered on the origin of the k-space is extracted.
- step 503 The details of step 503 will be described with reference to FIG. Figures 6 (a)-(d) schematically show the k-space data 401-1-1-401-4 of each block, where the gray part is the data. Is the area in which. At this time, data is selected along the circular trajectory 610 from the start point A to the end point B in the low-frequency region of k space, and the data on this circumference is arranged using the rotation angle of the circumference as the horizontal axis.
- Figure 6 (e) schematically shows the data array created for each block arranged so that the start point A and the end point B match.
- the horizontal axis represents the position k on the circumference centered on the k-space origin
- the vertical axis represents the signal strength.
- 611-1-1 611-4 are on the circumference extracted from 401-1-1 401-4, respectively. This shows the data array of.
- the data arrays 611-1-611-4 After the data arrays 611-1-611-4 have been created for each block in this way, the data arrays 611-1 of one block (for example, block 1) are used as a reference, and then the other data arrays 611-1 are used.
- the shift amount in the k-direction that is, the shift amount (rotation amount) in the rotation direction of 611-4 is determined, and corrected (step 504). Since the shift amount A k corresponds to a phase change in the space after the Fourier transform, the rotation amount is calculated using this property.
- FIG. 7 (a) schematically shows the projection of an echo signal with the horizontal axis representing the position (X) and the vertical axis representing the signal strength (I) (the range of the position is 1 ⁇ And).
- the projection 701-1 moves in parallel by ⁇ ⁇ and the projection
- FIG. 7 (b) shows a Fourier transform of these two projections, with the horizontal axis representing time (t) and the vertical axis representing the phase value of the signal corresponding to the movement ⁇ ⁇ of the projection.
- phase 702—1 is also 0.
- the phase 702-2 rotates corresponding to the movement amount ⁇ X.
- the phase and the movement amount ⁇ X are represented by Expression (1).
- K represents the length of the circumference
- 1 represents the dimension of the data obtained by Fourier-transforming k.
- each data array 611-1-1 611-4 is Fourier-transformed, and the Fourier-transformed data of the reference data array 611-1 and the other data array 611-2-611-4 are converted. Calculate the phase difference with the Fourier transformed data.
- phase difference between the data is calculated, for example, assuming that the complex data after the Fourier transform is C and D, the complex difference E between the two data is calculated from the following equations (3) and (4), and the difference is calculated. It can be calculated by calculating the force phase value ⁇ .
- FIG. 6 (f) schematically shows the calculated phase difference of the data of each block.
- 612-2—612-4 is a phase difference corresponding to each position shift (rotation direction shift) of the other data array 611-2—611-4 with respect to the reference data array 611-1 on the circumference. It is.
- the phase rotation with respect to the shift amount Ak in the k direction is given by the above equation (2), and the slope (2 ⁇ X Ak / K) of the phase difference can be obtained from the equation (2).
- the slope of the phase difference is
- the rotation of the data 401-2-401-4 of each block is corrected (step 506).
- the rotation correction 501 the k-space data 401-2-401-4 of each block is rotated by gridding in accordance with the amount of rotation 505-1-505-3 obtained in each block, so that rotation among body motions is performed. The component can be corrected.
- the rotation-corrected data is passed to a translation correction 502.
- phase difference is calculated using the k-space data 401-1 of the reference block and the data of each block after the rotation correction (steps 507-1 and 507-3).
- the amount of phase rotation can be obtained by calculating k-space data. Specifically, the amount of phase rotation can be obtained by applying the above equations (3) to (5) to k-space complex data. Can be.
- the phase amounts 508-1 to 508-3 calculated in this manner include, with respect to the time when the data 401-1 of the reference block was measured, the data of the subject at the time of measuring the data 401-2 to 401-4 of each block. Since the phase change caused by the translation is included, the data 401-2—401-4 are corrected by these phase amounts 508—1-1508—3 to remove the two-dimensional translation. — 1 1 1 1 1 1 3 are obtained.
- phase difference it is not necessary to use all of the measurement data, and it is possible to use a part of the measurement data.
- low-frequency data which is data in the same area, is used.
- FIGS. 8A and 8B show an example of a data array for calculating the amount of parallel movement.
- FIG. 8 (a) is a diagram showing a data array for obtaining parallel movement amounts in two directions (x-axis direction and y-axis direction).
- the line segment data 801 and 802 passing through the origins in the kx direction and the ky direction are also extracted from the data of the reference block and the data of each block to obtain the phase difference.
- the phase rotation expressed by the linear function is the position shift. Therefore, the calculated phase difference is fitted with a linear function.
- Each block data (k-space data) is rotated in the opposite direction by the amount of phase determined by a linear function in each direction. As a result, data 411 1 1 1 1 1 1 1 1 3 from which the translation has been removed in two directions is obtained.
- FIG. 8 (b) is a diagram showing a data array for obtaining the translation amount as a whole at one time.
- the low-frequency data 803 including the origin is extracted from the data of the reference block and the data of each block to obtain a phase difference, and the first-order plane fitting is performed.
- the first-order plane fitting is performed.
- phase difference calculated in the k space As described above, by removing the phase difference calculated in the k space as it is in the k space data force, it is possible to accurately detect and correct even a parallel movement within one pixel. Further, the accuracy of correction can be improved by fitting the obtained phase difference with a linear function or a linear plane function.
- phase difference into a pixel shift amount to correct the image data.
- any of these methods can be adopted.
- the phase calculated in steps 504 and 507 usually contains a lot of noise components, it is preferable to apply a median filter or a smoothing process and remove the noise components to improve the accuracy of correction.
- the rotational component of the body motion generated between the blocks is extracted by a simple method using the reference data (data array) created by extracting the measurement data force of each block.
- the amount of calculation required for body motion correction can be greatly reduced as a whole.
- the correlation method after setting detection accuracy, data for comparison is created at each pitch, and the amount of movement is set so that the correlation coefficient between the data and reference data that does not move is minimized. For example, if the detection range is ⁇ 5 pixels and the detection pitch is 0.1 pixel, 100 (5 ⁇ 2 ⁇ (I / O.1)) repetitive operations are required. On the other hand, in the present invention, the same movement amount in the unit of 0.1 pixel can be detected by one phase difference calculation.
- FIG. 9 shows a correction procedure in the present embodiment.
- the difference between the present embodiment and the first embodiment is that, in the pulse sequence of FIG. 3, the echo signals 3081 to 3084 obtained in the respective blocks 309-1 to 309-4 are transformed into rectangular coordinates for images.
- the data 405-11-1405-4 arranged in different coordinate systems is used, with the vertical axis as the phase encoding amount and the horizontal axis as the readout gradient magnetic field amount.
- the data 405-1 to 405-4 of each block are obtained by arranging the acquired echo signals in parallel according to the phase encoding amount.
- the body motion correction in the second embodiment also includes a rotation correction 901 and a parallel movement correction 502.
- the rotation correction 901 in order to obtain the amount of rotation between the acquired data 405-1 of the reference block and the acquired data 405-2-405-4 of the other blocks, the circumference is calculated.
- the above data array is created (steps 503-11-1503-4), and then the rotation angle of each block is calculated (steps 504-1-114-1504-3).
- the calculated rotation amount 902-1-902-3 includes the rotation amount caused by the body movement of the subject and the rotation angles of the respective blocks set in the sequence.
- the echo signal acquired in each block 3081—gridding 3084 into k-space for the image This makes it possible to correct body movement at the same time as gridding.
- Subsequent translation correction 502 is processed in the same manner as in the first embodiment.
- the amount of rotation is directly calculated without gridding the acquired data, the number of griddings required for image reconstruction can be reduced, and the image reconstruction time can be shortened.
- the imaging method based on the hybrid radial method As described above, in the first and second embodiments described above, the case where the imaging method based on the hybrid radial method is adopted has been described. However, the present invention can be applied to the imaging method based on the radial method. Such an embodiment will be described below.
- FIG. 10 shows a gradient pulse sequence using the radial sampling method.
- a gradient magnetic field 904 similar to the frequency encoding gradient magnetic field 905 is applied to the axis Gp of the phase encoding gradient magnetic field, and Gp, Gr for each repetition 907 of the pulse sequence.
- the amplitude of the gradient magnetic field 904, 905 applied to the axis is changed.
- FIG. 1B shows a case where 907 is repeated 12 times and echo signals of 906-1-906-C are obtained.
- the rotation angle ⁇ required to evenly fill the k-space is
- the gradient magnetic field outputs GP and GR of the Gp and Gr axes are G
- the output of the frequency encoding gradient magnetic field used in the orthogonal sampling method is G
- the repetition number is n (l ⁇ n ⁇ 12 )
- the rotation angle of such radial sampling is shifted a plurality of times, and the data obtained by the plurality of measurements are combined to reconstruct one image.
- k-space data by the radial sampling method to obtain one image The data are acquired in a plurality of blocks having different rotation start angles (angle offsets).
- one piece of image reconstruction data is divided into four blocks and shooting is performed, and each block 113-1-1113--4 acquires 12 echo signals, respectively.
- (b)-(e) schematically show the state where the echo signals acquired in each of the blocks 113-1-1113-4 are arranged in the k-space.
- the number of acquired echo signals and the rotation angle ⁇ are the same, but the rotation start angle (angle offset) 114 is different.
- the echo signals acquired in each of the blocks 113-1 to 113-4 are combined in a signal combining process 115, and final k-space data 116 is created.
- the rotation offset angles 114-1 and 114-4 are different between the blocks 113-1 and 113-4, the k-space data 116 can be sampled densely without overlapping echoes.
- the body movement correction includes the rotation correction and the parallel movement correction
- the first rotation correction is the same as in the first embodiment described above. That is, first, data of each block is gridded and rearranged as orthogonal k-space data, and then a data array on a predetermined circumference centered on the origin of coordinates is created.
- the radius from the center of k-space is R,
- each block 113-1—113-4 the low air frequency region of k-space is densely sampled, so the number of echoes obtained in each block Np (12 in the example of FIG. 11) Calculate the radius R expressed by the above equation, extract the data on the circumference from the start point A to the end point B, and create a data array with the horizontal axis as the rotation angle direction.
- the start point A and the end point B are points having the same k-space coordinates in all blocks.
- the phase difference between the reference block and the other blocks is calculated for the data obtained by Fourier transforming the data array, and the phase difference is calculated.
- the rotation amount is obtained from the inclination, and the data of each block is corrected.
- the translation correction is performed in the same manner as the translation correction 502 of the first embodiment, and the corrected k-space data is created.
- the k-space data after the correction is signal-coupled to obtain k-space data 116 for the image.
- the present invention is not limited to the contents disclosed in the above embodiments, and can take various forms based on the gist of the present invention.
- the force radial sampling method and the Neubris radial method described for the gradient echo pulse sequence do not depend on the type of the pulse sequence, and include the SE pulse sequence, the FSE pulse sequence, the EPI pulse sequence, and the like. Applicable to
- the forces described in the case of rotating the k-space with the Gr axis and the Gp axis in the two-dimensional plane are described as follows. It can correspond to any of the X, ⁇ ⁇ ⁇ , and ⁇ axes, and can perform oblique shooting and off-center shooting. Furthermore, rotation within a three-dimensional sphere can be performed.
- the number of blocks described in the case of the force is used.
- the number of blocks and the number of echoes in a block can be set arbitrarily. In this case, the same processing is performed. Similar effects can be obtained.
- the number of echoes to be acquired, the rotation angle, and the number of segments can be arbitrarily set.
- the data array is designed to detect a deviation of data in the rotation direction. Any data with the same coordinates in a common area including the center of k-space is acceptable. For example, a part of data on the circumference, a semicircle part, or data on the circumference may be thinned out. Further, data in an area having a certain width rather than one row of data may be used. In this case, data obtained by adding data in the same radial direction is used.
- the present invention can be applied to continuous shooting such as dynamic shooting or fluoroscopy, or to an echo-sharing method in which a part of data in the k space is updated during the continuous shooting.
- the calculation for the amount of rotation can be performed in a very short time. For example, when the measurement 310 shown in FIG. 3 is continuously repeated, the calculation is performed between two blocks. It is possible to reflect the amount of rotation to the measurement of the next block or a further block.
- FIG. 12 is a diagram illustrating an embodiment of a continuous imaging method to which the imaging method of the first embodiment is applied.
- 1101 indicates the measurement of each block
- 1102 indicates the data array created from the acquired data of each block
- 1103 indicates the rotational component of the body motion since the measurement of the reference block (here, block 1)
- 1104 indicates body movement correction
- 1105 indicates a position update process using the rotation amount 1103.
- the measurement position of block 3 that is, the rotation angle is adjusted so as to eliminate the rotation amount generated between block 1 (reference block) and block 2. That is, assuming that the rotation amount of block 1 and block 2 is ⁇ , in block 3, the k-space data is acquired in the direction parallel to the ky axis. And the gradient magnetic field 304 in the frequency encoding direction is determined, but the gradient magnetic fields 303 and 304 are adjusted so that they are inclined by ⁇ with respect to the ky axis.
- the gradient magnetic field outputs GP and GR of the phase encoding gradient magnetic field Gp and the frequency encoding gradient magnetic field Gr are represented by G when the output of the frequency encoding gradient magnetic field used in orthogonal sampling is G and the number of blocks is n.
- GR (n) GX cos (X ( ⁇ — 1)- ⁇ ⁇ )
- the acquired data is arranged in k-space coordinates determined by the original gradient magnetic field strength.
- the data of block 3 is data that does not include the influence of rotation up to block 2 measurement.
- a data array 1102-3 of the acquired data is created, and a rotation amount 1103-2 is obtained from the data array 1102-1 created from the data of the reference block.
- Rotation correction is performed based on 1103-2 and parallel movement correction is performed on the rotation-corrected data.
- the rotation angle in the block measurement is determined by using the rotation amount obtained by calculating the rotation amount 1103-1 of the rotation amount 1103-1 and the rotation amount 1103-1 of the block 1 and the block 2.
- the parallel movement amount calculated in the parallel movement correction step 502 of FIG. (Or the amount of phase), it is also possible to change the conditions of the subsequent measurement.
- at least one of the reception phase and frequency for receiving the echo signal is changed in accordance with the amount of translation.
- Mat is the image matrix (number of pixels) after reconstruction.
- the data acquired in each block does not include an error component due to the amount of translation. ! / ⁇
- the change of the measurement condition corresponding to the translation amount may be executed by itself, and in such a case, the same correction processing as the correction of the body movement rotation component in the first or second embodiment described above.
- the present invention is applied to data obtained by the hybrid radial method.
- the segmented radial sampling method can be similarly applied. It is also possible to correct the rotation amount (start offset amount) in the measurement of the next block using the rotation amount between the second block. It is also possible to execute this together with the change of the measurement condition corresponding to the parallel movement.
- the fourth embodiment an embodiment has been described in which the rotation component and the Z or translation component of body motion are detected, and the measurement conditions of subsequent blocks are changed based on the detected components.
- the control can be executed independently of the body motion correction of the block data. For example, it is possible to reduce artefacts based on body movement to some extent only by controlling the measurement conditions. At the same time, applying body motion correction to the acquired data can further reduce artifacts.
- the data of the block in which the body motion has been detected may be measured again by controlling the measurement conditions.
- the amount of body movement of a subject is directly calculated and corrected in the k-space, in contrast to the radial sampling method or the Neubris radial method in which the phase encoding is combined with the radial sampling method.
- FIG. 1 is a diagram illustrating a sampling method and k-space.
- FIG. 2 is a diagram showing an overall configuration of an MRI apparatus to which the present invention is applied.
- FIG. 3 is a diagram illustrating a pulse sequence of the Ivritz radial method to which the present invention is applied.
- FIG. 4 is a diagram illustrating the concept of gridding.
- FIG. 5 is a view for explaining a processing procedure in the first embodiment.
- FIG. 6 is a view for explaining signal processing (rotation correction) in the first embodiment.
- FIG. 7 is a view for explaining the mathematical properties of Fourier transform.
- FIG. 8 is a view for explaining signal processing (parallel movement correction) in the first embodiment.
- FIG. 9 is a view for explaining a processing procedure in the second embodiment.
- FIG. 10 is a diagram illustrating a pulse sequence of a radial sampling method to which the present invention is applied.
- FIG. 11 is a diagram illustrating a third embodiment.
- FIG. 12 is a diagram illustrating a fourth embodiment.
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WO2008152937A1 (ja) * | 2007-06-14 | 2008-12-18 | Hitachi Medical Corporation | 磁気共鳴イメージング装置及び傾斜磁場に起因する誤差補正方法 |
JP2009131613A (ja) * | 2007-11-02 | 2009-06-18 | Toshiba Corp | 磁気共鳴イメージング装置 |
WO2012043311A1 (ja) * | 2010-09-27 | 2012-04-05 | 株式会社 日立メディコ | 磁気共鳴イメージング装置および磁気共鳴イメージング方法 |
JP2013240713A (ja) * | 2007-04-27 | 2013-12-05 | Koninkl Philips Nv | プロペラmri用磁気共鳴装置及び方法 |
WO2014185323A1 (ja) * | 2013-05-17 | 2014-11-20 | 株式会社 日立メディコ | 磁気共鳴イメージング装置および磁気共鳴イメージング方法 |
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JP6087543B2 (ja) * | 2012-09-03 | 2017-03-01 | 東芝メディカルシステムズ株式会社 | 磁気共鳴イメージング装置 |
CN112967297B (zh) * | 2021-03-23 | 2024-05-03 | 中国科学院深圳先进技术研究院 | 磁共振氧十七代谢成像方法、装置、存储介质及终端设备 |
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