WO2004103212A1 - Protesis compuesta de doble malla que corrige defectos de pared abdominal, e impide la formacion de adherencias en la interfaz peritoneal - Google Patents
Protesis compuesta de doble malla que corrige defectos de pared abdominal, e impide la formacion de adherencias en la interfaz peritoneal Download PDFInfo
- Publication number
- WO2004103212A1 WO2004103212A1 PCT/ES2004/000222 ES2004000222W WO2004103212A1 WO 2004103212 A1 WO2004103212 A1 WO 2004103212A1 ES 2004000222 W ES2004000222 W ES 2004000222W WO 2004103212 A1 WO2004103212 A1 WO 2004103212A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- mesh
- abdominal wall
- prosthesis
- peritoneal
- interface
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
Definitions
- the present invention refers to a prosthesis composed of an implantable double mesh to solve abdominal wall defects, characterized by stimulating the proliferation of connective tissue and by avoiding the formation of adhesions and erosions on the viscera, to be used in the field of surgery repair of different types of hernias located in the abdominal wall.
- the prostheses of group 1 which are integrated into the recipient tissue, are prostheses made of threads, with a knotted weft, leaving small physical spaces to form a mesh or network, arranged primarily in one plane.
- These meshed prostheses are currently made of plastic materials, the most common being polypropylene, and polyester, nylon and Teflon are also used, and on occasions, resorbable material threads, such as polyglactin (Vicryl®) and polyglycolic, come into its composition. (Dexon®), which after a period of residence in the body, the recipient tissue breaks them down. Once implanted, these prostheses are surrounded by the growth of fibroblasts and connective tissue between their spaces, being completely encompassed in the tissue.
- This type of prosthesis meets the requirements of physical and biomechanical resistance very well, and thanks to its complete incorporation into the recipient tissue, the defects are permanently repaired.
- they have a major drawback, since these prostheses cannot be left in contact with the viscera, mainly the intestine, because they generate adhesions or sticking with them, sometimes capable of causing occlusions of the intestine.
- erosion over the intestine can generate a fistula, with the lumen of the intestine communicating with the tissues of the abdominal wall. These fistulas are difficult to treat, carrying risk of organ function and even of life itself.
- Group 2 prostheses which are not intimately integrated into the tissue, but are encapsulated, are designed to minimize the possibility of adhesion formation and visceral erosion. They are made with sheets of continuous plastic material without gaps, although some have micropores, mainly silicone and expanded polytetrafluoroethylene. These continuous sheets never fully integrate into the tissue, forming a capsule around them. Being laminar, the intestine is not eroded, generally eliminating the possibility of fistula formation.
- a drawback of these prostheses is that the lack of intimate integration to the tissue prevents the defect from healing over time by the connective tissue itself, so that hemial recurrences are quite frequent.
- Another important drawback is that these wall prostheses are their high economic cost. Sheets of absorbable material have also been made over time, but these do not have great advantages and they do have more disadvantages, so they are practically not used.
- a prosthesis that stimulates the connective tissue, performing a support or scaffolding function, allowing defense cells and fibroblasts to proliferate within it, which perform a collagen connective filling, joining the newly formed tissue.
- the prosthesis should be ideally inexpensive.
- the DOUBLE MESH COMPOSITE PROSTHESIS has been designed THAT CORRECTS DEFECTS OF THE ABDOMINAL WALL, AND PREVENTS THE FORMATION OF ADHERENCES IN THE PERITONEAL INTERFACE, object of the present invention.
- the invention contemplates a new type of wall prosthesis whose manufacture has contemplated the advantages of the two current types of prostheses.
- the recommended prosthesis is built by two meshes that can be of variable porosity, always with the aim that the integration tissue and the vessels penetrate it, in such a way that the prosthesis serves as a support or frame.
- the two meshes of circular or elongated shape are of different sizes and both are joined by suture or by a heat-sealed union, thus there is a central area of the prosthesis formed by the two meshes in contact, a fact that will induce a thicker formation of connective tissue .
- the joining area of both meshes must leave a small flap in the mesh to be placed externally in the hole or defect, so that it can be anchored to the receiving tissue.
- the other mesh much more extensive than the previous one, will be placed inside the hole to be repaired and without any fixation, it will allow the positive pressure of the abdomen cavity and the viscera themselves to favor its support on the wall in such a way that it acts as a retaining wall.
- the biomechanical resistance is superior to that obtained with simple implants that have been placed until now on the margins of the hole or externally exceeding the margins of the same.
- any possibility of "buttonhole hernias", produced by disinsertion of the mesh is eliminated, when the mesh is placed only as a single prosthesis, occluding the hemiary orifice.
- this second mesh will be covered with a sheet of some composite material such as polyurethane, Teflon or some type of biodegradable or non-biodegradable polymeric product, which acts as a barrier and prevents the viscera from adhering to the mesh and therefore prevents the formation of adhesions. and erosions that cause intestinal fistulas.
- some composite material such as polyurethane, Teflon or some type of biodegradable or non-biodegradable polymeric product, which acts as a barrier and prevents the viscera from adhering to the mesh and therefore prevents the formation of adhesions. and erosions that cause intestinal fistulas.
- These last two components may be joined by means of some adhesive for internal use, or preferably by molding or thermoplastic fusion.
- the prostheses can be made using a single material, preferably one of the optimally biotolerated ones, such as polypropylene, polyester, and which also provides good biomechanical resistance with them.
- This new prosthesis design also has the advantage that it is simple and quick to place in circular hernia holes (the most frequent), since once the internally located prosthesis is introduced, the extema overlaps on the edges of the hole. Due to the materials used, their cost may be significantly lower than those currently on the market.
- Figure 1 shows a diagram of the placement of a prosthesis model in the muscle-fascia hole of the abdominal wall.
- Figure 2 shows a perspective view of a general elevation of a prosthesis model of the current invention.
- Figure 3 shows a cross section of the model in Figure 2.
- Figure 4 shows a frontal view of the prosthesis from its external side.
- Figure 5 shows a front view of the prosthesis from its internal side.
- the presented prosthesis comprises a reticular mesh (1) of biotolerated, resistant and flexible material, preferably of the polyoliphine type, joined to another mesh of the same characteristics (2) by a heat-sealed suture / union (3), which leaves a flap on it, which will allow it to be anchored to the perimeter of the defect.
- the innermost sheet (2) must be larger than the previous one on the surface since it will remain inside the hole, and will be covered on its inner side by a sheet (4) of some smooth material such as polyurethane, Teflon or some type of biodegradable or non-biodegradable polymeric product, which acts as a barrier and prevents the viscera from adhering to the second mesh (2) and therefore prevents the formation of adhesions and erosions that cause intestinal fistulas.
- the contact of the two meshes causes the connective proliferation tissue (fibroblasts and the extracellular matrix of deposit) together with neovessels, to form a thick layer of tissue that will occlude the entire defect, preventing hemial recurrences.
- the most internal aspect will favor the mesothelial deposit and will give rise to the formation of a neoperitoneum that will prevent adhesion formation and the erosion of the viscera of the abdominal cavity.
- the prosthesis will be located in the defect to be repaired as shown in Figure 1, in which the first mesh (1) anchored to the defect by points (5) can be seen, in turn both meshes joined together (3) and the second mesh (2) covered on its internal side by another sheet facilitating the mesothelial deposit.
- This last mesh (2) is not fixed since it will be the intra-abdominal pressure itself and the content of that cavity that will be in charge of fixing it to the wall, this obviates the fixation with material, which always decreases the foreign body material that it is left in the tissues.
- this second mesh reinforces the action of the most external one and provides additional support to the repair, being able to avoid the appearance of new hernias.
- the resulting prosthesis can be made in various dimensions, so that it can be adapted to needs depending on the size of the defect. On the other hand, and given the components of the same, this design can be competitive from an economic point of view with others already existing in the market
Abstract
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200301158A ES2220213B1 (es) | 2003-05-20 | 2003-05-20 | Protesis compuesta de doble malla que corrige defectos de pared abdominal, e impide la formacion de adherencias en la interfaz peritoneal. |
ESP200301158 | 2003-05-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2004103212A1 true WO2004103212A1 (es) | 2004-12-02 |
Family
ID=33462366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/ES2004/000222 WO2004103212A1 (es) | 2003-05-20 | 2004-05-19 | Protesis compuesta de doble malla que corrige defectos de pared abdominal, e impide la formacion de adherencias en la interfaz peritoneal |
Country Status (2)
Country | Link |
---|---|
ES (1) | ES2220213B1 (es) |
WO (1) | WO2004103212A1 (es) |
Cited By (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006008429A1 (en) * | 2004-07-20 | 2006-01-26 | Stephen George Edward Barker | Umbilical or paraumbilical hernia repair prosthesis |
FR2924330A1 (fr) * | 2007-12-03 | 2009-06-05 | Sofradim Production Sa | Implant pour hernie parastomiale |
AU2008332811B2 (en) * | 2007-12-03 | 2014-04-10 | Sofradim Production | Implant for parastomal hernia |
CN104997537A (zh) * | 2015-08-25 | 2015-10-28 | 林新颖 | 临时开关腹器 |
US9445883B2 (en) | 2011-12-29 | 2016-09-20 | Sofradim Production | Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit |
US9499927B2 (en) | 2012-09-25 | 2016-11-22 | Sofradim Production | Method for producing a prosthesis for reinforcing the abdominal wall |
US9526603B2 (en) | 2011-09-30 | 2016-12-27 | Covidien Lp | Reversible stiffening of light weight mesh |
US9554887B2 (en) | 2011-03-16 | 2017-01-31 | Sofradim Production | Prosthesis comprising a three-dimensional and openworked knit |
US9622843B2 (en) | 2011-07-13 | 2017-04-18 | Sofradim Production | Umbilical hernia prosthesis |
US9750837B2 (en) | 2012-09-25 | 2017-09-05 | Sofradim Production | Haemostatic patch and method of preparation |
US9820838B2 (en) | 2012-04-10 | 2017-11-21 | Ethicon, Inc. | Single plane tissue repair patch |
US9820839B2 (en) | 2012-04-10 | 2017-11-21 | Ethicon, Inc. | Single plane tissue repair patch having a locating structure |
US9820837B2 (en) | 2012-04-10 | 2017-11-21 | Ethicon, Inc. | Single plane tissue repair patch |
US9839505B2 (en) | 2012-09-25 | 2017-12-12 | Sofradim Production | Prosthesis comprising a mesh and a strengthening means |
US9877820B2 (en) | 2014-09-29 | 2018-01-30 | Sofradim Production | Textile-based prosthesis for treatment of inguinal hernia |
US9932695B2 (en) | 2014-12-05 | 2018-04-03 | Sofradim Production | Prosthetic porous knit |
US9931198B2 (en) | 2015-04-24 | 2018-04-03 | Sofradim Production | Prosthesis for supporting a breast structure |
US9980802B2 (en) | 2011-07-13 | 2018-05-29 | Sofradim Production | Umbilical hernia prosthesis |
US10070948B2 (en) | 2008-06-27 | 2018-09-11 | Sofradim Production | Biosynthetic implant for soft tissue repair |
US10080639B2 (en) | 2011-12-29 | 2018-09-25 | Sofradim Production | Prosthesis for inguinal hernia |
US10159555B2 (en) | 2012-09-28 | 2018-12-25 | Sofradim Production | Packaging for a hernia repair device |
US10184032B2 (en) | 2015-02-17 | 2019-01-22 | Sofradim Production | Method for preparing a chitosan-based matrix comprising a fiber reinforcement member |
US10213283B2 (en) | 2013-06-07 | 2019-02-26 | Sofradim Production | Textile-based prosthesis for laparoscopic surgery |
US10327882B2 (en) | 2014-09-29 | 2019-06-25 | Sofradim Production | Whale concept—folding mesh for TIPP procedure for inguinal hernia |
US10363690B2 (en) | 2012-08-02 | 2019-07-30 | Sofradim Production | Method for preparing a chitosan-based porous layer |
US10368971B2 (en) | 2007-12-03 | 2019-08-06 | Sofradim Production | Implant for parastomal hernia |
US10405960B2 (en) | 2013-06-07 | 2019-09-10 | Sofradim Production | Textile-based prothesis for laparoscopic surgery |
US10646321B2 (en) | 2016-01-25 | 2020-05-12 | Sofradim Production | Prosthesis for hernia repair |
US10675137B2 (en) | 2017-05-02 | 2020-06-09 | Sofradim Production | Prosthesis for inguinal hernia repair |
US10682215B2 (en) | 2016-10-21 | 2020-06-16 | Sofradim Production | Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained |
US10743976B2 (en) | 2015-06-19 | 2020-08-18 | Sofradim Production | Synthetic prosthesis comprising a knit and a non porous film and method for forming same |
US10865505B2 (en) | 2009-09-04 | 2020-12-15 | Sofradim Production | Gripping fabric coated with a bioresorbable impenetrable layer |
US11065368B2 (en) | 2013-03-15 | 2021-07-20 | Cook Biotech Incorporated | Drug eluting graft constructs and methods |
US11471257B2 (en) | 2018-11-16 | 2022-10-18 | Sofradim Production | Implants suitable for soft tissue repair |
US11970798B2 (en) | 2009-09-04 | 2024-04-30 | Sofradim Production | Gripping fabric coated with a bioresorbable impenetrable layer |
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US5634944A (en) * | 1995-02-23 | 1997-06-03 | The Nemours Foundation | Body membrane prosthesis |
US5743917A (en) * | 1993-01-13 | 1998-04-28 | Saxon; Allen | Prosthesis for the repair of soft tissue defects |
US6383201B1 (en) * | 1999-05-14 | 2002-05-07 | Tennison S. Dong | Surgical prosthesis for repairing a hernia |
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2003
- 2003-05-20 ES ES200301158A patent/ES2220213B1/es not_active Expired - Fee Related
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2004
- 2004-05-19 WO PCT/ES2004/000222 patent/WO2004103212A1/es active Application Filing
Patent Citations (3)
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US5743917A (en) * | 1993-01-13 | 1998-04-28 | Saxon; Allen | Prosthesis for the repair of soft tissue defects |
US5634944A (en) * | 1995-02-23 | 1997-06-03 | The Nemours Foundation | Body membrane prosthesis |
US6383201B1 (en) * | 1999-05-14 | 2002-05-07 | Tennison S. Dong | Surgical prosthesis for repairing a hernia |
Cited By (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006008429A1 (en) * | 2004-07-20 | 2006-01-26 | Stephen George Edward Barker | Umbilical or paraumbilical hernia repair prosthesis |
FR2924330A1 (fr) * | 2007-12-03 | 2009-06-05 | Sofradim Production Sa | Implant pour hernie parastomiale |
WO2009071998A2 (en) * | 2007-12-03 | 2009-06-11 | Sofradim Production | Implant for parastomal hernia |
WO2009071998A3 (en) * | 2007-12-03 | 2009-07-23 | Sofradim Production | Implant for parastomal hernia |
JP2011505220A (ja) * | 2007-12-03 | 2011-02-24 | ソフラディム・プロデュクスィヨン | 小孔周辺(parastomal)ヘルニアの為のインプラント |
AU2008332811B2 (en) * | 2007-12-03 | 2014-04-10 | Sofradim Production | Implant for parastomal hernia |
US10368971B2 (en) | 2007-12-03 | 2019-08-06 | Sofradim Production | Implant for parastomal hernia |
US10070948B2 (en) | 2008-06-27 | 2018-09-11 | Sofradim Production | Biosynthetic implant for soft tissue repair |
US10865505B2 (en) | 2009-09-04 | 2020-12-15 | Sofradim Production | Gripping fabric coated with a bioresorbable impenetrable layer |
US11970798B2 (en) | 2009-09-04 | 2024-04-30 | Sofradim Production | Gripping fabric coated with a bioresorbable impenetrable layer |
US11612472B2 (en) | 2011-03-16 | 2023-03-28 | Sofradim Production | Prosthesis comprising a three-dimensional and openworked knit |
US9554887B2 (en) | 2011-03-16 | 2017-01-31 | Sofradim Production | Prosthesis comprising a three-dimensional and openworked knit |
US10472750B2 (en) | 2011-03-16 | 2019-11-12 | Sofradim Production | Prosthesis comprising a three-dimensional and openworked knit |
US11039912B2 (en) | 2011-07-13 | 2021-06-22 | Sofradim Production | Umbilical hernia prosthesis |
US10709538B2 (en) | 2011-07-13 | 2020-07-14 | Sofradim Production | Umbilical hernia prosthesis |
US9980802B2 (en) | 2011-07-13 | 2018-05-29 | Sofradim Production | Umbilical hernia prosthesis |
US11903807B2 (en) | 2011-07-13 | 2024-02-20 | Sofradim Production | Umbilical hernia prosthesis |
US9622843B2 (en) | 2011-07-13 | 2017-04-18 | Sofradim Production | Umbilical hernia prosthesis |
US9526603B2 (en) | 2011-09-30 | 2016-12-27 | Covidien Lp | Reversible stiffening of light weight mesh |
US11471256B2 (en) | 2011-12-29 | 2022-10-18 | Sofradim Production | Prosthesis for inguinal hernia |
US11925543B2 (en) | 2011-12-29 | 2024-03-12 | Sofradim Production | Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit |
US11266489B2 (en) | 2011-12-29 | 2022-03-08 | Sofradim Production | Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit |
US10342652B2 (en) | 2011-12-29 | 2019-07-09 | Sofradim Production | Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit |
US9445883B2 (en) | 2011-12-29 | 2016-09-20 | Sofradim Production | Barbed prosthetic knit and hernia repair mesh made therefrom as well as process for making said prosthetic knit |
US10080639B2 (en) | 2011-12-29 | 2018-09-25 | Sofradim Production | Prosthesis for inguinal hernia |
US9820837B2 (en) | 2012-04-10 | 2017-11-21 | Ethicon, Inc. | Single plane tissue repair patch |
US9820839B2 (en) | 2012-04-10 | 2017-11-21 | Ethicon, Inc. | Single plane tissue repair patch having a locating structure |
US9820838B2 (en) | 2012-04-10 | 2017-11-21 | Ethicon, Inc. | Single plane tissue repair patch |
US10363690B2 (en) | 2012-08-02 | 2019-07-30 | Sofradim Production | Method for preparing a chitosan-based porous layer |
US9839505B2 (en) | 2012-09-25 | 2017-12-12 | Sofradim Production | Prosthesis comprising a mesh and a strengthening means |
US9499927B2 (en) | 2012-09-25 | 2016-11-22 | Sofradim Production | Method for producing a prosthesis for reinforcing the abdominal wall |
US9750837B2 (en) | 2012-09-25 | 2017-09-05 | Sofradim Production | Haemostatic patch and method of preparation |
US10159555B2 (en) | 2012-09-28 | 2018-12-25 | Sofradim Production | Packaging for a hernia repair device |
US11065368B2 (en) | 2013-03-15 | 2021-07-20 | Cook Biotech Incorporated | Drug eluting graft constructs and methods |
US10213283B2 (en) | 2013-06-07 | 2019-02-26 | Sofradim Production | Textile-based prosthesis for laparoscopic surgery |
US11304790B2 (en) | 2013-06-07 | 2022-04-19 | Sofradim Production | Textile-based prothesis for laparoscopic surgery |
US11622845B2 (en) | 2013-06-07 | 2023-04-11 | Sofradim Production | Textile-based prothesis for laparoscopic surgery |
US10405960B2 (en) | 2013-06-07 | 2019-09-10 | Sofradim Production | Textile-based prothesis for laparoscopic surgery |
US10653508B2 (en) | 2014-09-29 | 2020-05-19 | Sofradim Production | Textile-based prosthesis for treatment of inguinal hernia |
US11291536B2 (en) | 2014-09-29 | 2022-04-05 | Sofradim Production | Whale concept-folding mesh for TIPP procedure for inguinal hernia |
US11589974B2 (en) | 2014-09-29 | 2023-02-28 | Sofradim Production | Textile-based prosthesis for treatment of inguinal hernia |
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US10327882B2 (en) | 2014-09-29 | 2019-06-25 | Sofradim Production | Whale concept—folding mesh for TIPP procedure for inguinal hernia |
US10745835B2 (en) | 2014-12-05 | 2020-08-18 | Sofradim Production | Prosthetic porous knit |
US11713526B2 (en) | 2014-12-05 | 2023-08-01 | Sofradim Production | Prosthetic porous knit |
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US11359313B2 (en) | 2014-12-05 | 2022-06-14 | Sofradim Production | Prosthetic porous knit |
US10184032B2 (en) | 2015-02-17 | 2019-01-22 | Sofradim Production | Method for preparing a chitosan-based matrix comprising a fiber reinforcement member |
US10815345B2 (en) | 2015-02-17 | 2020-10-27 | Sofradim Production | Method for preparing a chitosan-based matrix comprising a fiber reinforcement member |
US10660741B2 (en) | 2015-04-24 | 2020-05-26 | Sofradim Production | Prosthesis for supporting a breast structure |
US11439498B2 (en) | 2015-04-24 | 2022-09-13 | Sofradim Production | Prosthesis for supporting a breast structure |
US9931198B2 (en) | 2015-04-24 | 2018-04-03 | Sofradim Production | Prosthesis for supporting a breast structure |
US11826242B2 (en) | 2015-06-19 | 2023-11-28 | Sofradim Production | Synthetic prosthesis comprising a knit and a non porous film and method for forming same |
US10743976B2 (en) | 2015-06-19 | 2020-08-18 | Sofradim Production | Synthetic prosthesis comprising a knit and a non porous film and method for forming same |
CN104997537A (zh) * | 2015-08-25 | 2015-10-28 | 林新颖 | 临时开关腹器 |
US11389282B2 (en) | 2016-01-25 | 2022-07-19 | Sofradim Production | Prosthesis for hernia repair |
US10646321B2 (en) | 2016-01-25 | 2020-05-12 | Sofradim Production | Prosthesis for hernia repair |
US11696819B2 (en) | 2016-10-21 | 2023-07-11 | Sofradim Production | Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained |
US10682215B2 (en) | 2016-10-21 | 2020-06-16 | Sofradim Production | Method for forming a mesh having a barbed suture attached thereto and the mesh thus obtained |
US11672636B2 (en) | 2017-05-02 | 2023-06-13 | Sofradim Production | Prosthesis for inguinal hernia repair |
US10675137B2 (en) | 2017-05-02 | 2020-06-09 | Sofradim Production | Prosthesis for inguinal hernia repair |
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Also Published As
Publication number | Publication date |
---|---|
ES2220213A1 (es) | 2004-12-01 |
ES2220213B1 (es) | 2006-01-16 |
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