WO2004089273A1 - Trousse pour solution chimique - Google Patents

Trousse pour solution chimique Download PDF

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Publication number
WO2004089273A1
WO2004089273A1 PCT/JP2003/004490 JP0304490W WO2004089273A1 WO 2004089273 A1 WO2004089273 A1 WO 2004089273A1 JP 0304490 W JP0304490 W JP 0304490W WO 2004089273 A1 WO2004089273 A1 WO 2004089273A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
drug
liquid
dissolving
dissolution
Prior art date
Application number
PCT/JP2003/004490
Other languages
English (en)
Japanese (ja)
Inventor
Yoichi Kirigaya
Original Assignee
Yoichi Kirigaya
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoichi Kirigaya filed Critical Yoichi Kirigaya
Priority to AU2003236010A priority Critical patent/AU2003236010A1/en
Priority to PCT/JP2003/004490 priority patent/WO2004089273A1/fr
Publication of WO2004089273A1 publication Critical patent/WO2004089273A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2037—Separating means having valve means

Definitions

  • the present invention relates to a drug solution kit, and more particularly, to a drug solution kit in which a drug and a dissolving solution are separately prepared, and the drug and the dissolving solution are mixed by separating them during use to prepare a drug solution.
  • Japanese Utility Model Application Laid-Open No. 2-866533 discloses an infusion container having a bag in which a solution for dissolution is sealed and a capsule for holding a vial. In this container, the capsule is rotated so that the puncture needle fixed to one end of the bag penetrates the cap portion of the vial, thereby mixing the solution and the drug.
  • Japanese Patent Application Laid-Open No. 5-1932377 discloses an infusion device in which, contrary to the above-mentioned utility model, a puncture needle attached to a back is movable and the puncture needle penetrates a cap of a vial. ing.
  • the present invention includes a dissolving container filled with a dissolving liquid, a drug container filled with a drug, and a coupling mechanism for connecting these, and the coupling mechanism includes a dissolving container coupling portion, a drug container storage portion, and a liquid-passable portion.
  • the chemical solution is characterized in that, by separating the dissolving container connecting part and the chemical container housing part from each other, the liquid conduit in the connector is opened and the chemical and the dissolving liquid are mixed. It is a kit. BRIEF DESCRIPTION OF THE FIGURES
  • FIG. 1 is a drawing showing the appearance of the drug solution kit of the present invention.
  • Fig. 2 is a cross-sectional view (without a drug container attached) showing the state of the coupling mechanism when liquid passage is disabled.
  • FIG. 3 is a cross-sectional view of the coupling mechanism when liquid passage is enabled.
  • Fig. 1 is a drawing showing the appearance of the drug solution kit of the present invention.
  • Fig. 2 is a cross-sectional view showing the state of the coupling mechanism when the liquid is not allowed to pass (drug not attached).
  • FIG. 4 is a cross-sectional view of the coupling mechanism when the above-mentioned state is set.
  • 1 is a drug solution kit
  • 2 is a dissolution container
  • 3 is a drug container
  • 4 is a coupling mechanism
  • 4a is a dissolution container coupling section
  • 4b is a drug container storage section
  • 4c is a connector
  • 5 is a connector.
  • the drug kit of the present invention comprises a dissolving container 2, a drug container 3, and a coupling mechanism 4 connecting these.
  • the coupling mechanism 4 is composed of a dissolution container coupling portion 4a having a closure 5 at a distal end portion, a drug container storage portion 4b, and a connector 4c.
  • the medicine container housing part 4b constituting the coupling mechanism 4 is provided with a screw cleaner 9 and an elastic ring 10 on the upper side, and this part can hold and seal the medicine container.
  • a closure plug 5 held by a support plate 8 is provided on the lower side. Since the support plate 8 is a fin formed radially around the stopper 5, a liquid can freely pass between the support plates 8.
  • the dissolving vessel connecting part 4a is bonded or fused at its lower part to the dissolving vessel 2 filled with the dissolving liquid, and the upper part is a support plate 8 like the drug container storage part 4b.
  • a retained closure plug 5 is provided. Since the support plate 8 also has the same configuration as above, the liquid can freely flow between them.
  • the connector 4c has a partition wall 7 in the vicinity of the center thereof, and a liquid passage tube 6 is provided in the center thereof.
  • ring-shaped projections 12 are provided to be engaged with the distal end projections 11 of the dissolution container coupling section 4a and the medicine container storage section 4b. It has a function to prevent liquid leakage.
  • the mechanism through which the liquid flow tube 6 in the connector is opened and the drug and the dissolving liquid can be mixed is as follows. First, the states of the dissolving container connecting portion 4a, the drug container storing portion 4b, and the connector 4c during distribution and storage are as shown in FIG. In this state, the liquid pipe 6 is closed by the stopper 5 from above and below, so that the dissolving liquid (not shown) in the dissolving vessel 2 can flow into the dissolving vessel connecting portion 4a. However, it cannot flow into the medicine container storage part 4 b and further into the medicine container 3 via the liquid passage 6.
  • the drug container 3 and the drug storage section 4b are screw-fastened.
  • the present invention is not limited to this. If it is possible to prevent fixation and leakage of the solution for dissolution, Can be used without restrictions.
  • the outer periphery of the opening of the medicine container may be made of an elastic material and held by the elasticity of the medicine container, or the outer periphery of the opening of the medicine container may be adhered or fused to the medicine container.
  • the dissolving container 2 is made of various water-impermeable materials.
  • a flexible polymer material such as a soft vinyl chloride resin or a polyolefin resin is preferably used.
  • the material forming the coupling mechanism 4 has high elasticity such that the liquid passage tube can be reliably sealed during distribution and the like, and has high hermeticity such that water does not leak from unnecessary portions during use. It must be a material that can provide properties and high machining accuracy. Examples of such a material include thermoplastic plastics such as polyvinyl chloride, polyethylene, and polypropylene, and thermosetting plastics such as epoxy resin and polyurethane.
  • the drug and the dissolving solution used in the drug kit of the present invention are not particularly limited.
  • examples of such agents include ampicillin, carpenicillin, sulpenicillin, ticalcillin, cefazolin, ceftizoxime, cefotiam, cefmenoxime, cefacetril, cefamandole, cephalolidine, cefol taxime, cefolitam Antibiotics and salts thereof, such as tetane, cefoperazone, cefsulodin, ceftezole, cefviramide, cefumesol, cefuroxime, vancomycin, piperacillin, phos-mycin, mouth moxef, imidenem'sirastin, melodenem, etc.
  • Anti-tumor agents such as mitomycin C, full-age lauracil, tegafur, and shiyubarabine and salts thereof, anti-ulcer agents such as famotidine, ranitidine, and cimetidine and their salts, etc.
  • Drugs that require time mixing are included.
  • the dissolving solution include distilled water for injection, physiological saline, glucose solution, and an infusion solution and a diluting agent obtained by adding appropriate vitamins and electrolytes thereto.
  • the liquid passage tube 6 is opened by an unconventional operation of separating, the drug and the dissolving liquid are mixed by mistake compared to a conventional product in which the pushing operation is searched for.
  • the drug container and the coupling mechanism are packaged with, for example, a shrink film or the like, and when used, provided on the film.
  • the tape may be peeled off from the peeling tape or the peeled portion.
  • the medicine container 3 has been described as being already set. However, for example, the medicine container 3 and other parts (the dissolving container 2 and the coupling mechanism 4 bonded or fused to the dissolving container 2) may be used. ), And separately sold drug dissolving bags having a joint part that matches the mouth of the drug container 3.At the medical institution used, select the drug container 3 containing the necessary drug, and It can also be used in combination with.
  • the present invention provides a mechanism for connecting the dissolving container 2 and the drug container 3 and allowing the dissolving solution to flow therethrough.
  • the stopper provided moves to open a fluid pipe in the connector, which takes a new mechanism. Availability in the café industry
  • the drug kit of the present invention does not use a puncture needle, there is no possibility of an accident and there is no special treatment after use. Moreover, since the use of relatively error hardly causes movement to detach, in which accidents which minimize that liquid for dissolving the drug will be mixed by mistake ⁇
  • the medicine container can be selected, it can be used as a general medicine kit.
  • the drug kit of the present invention can be widely used in medical practice as it has few accidents and is versatile.

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

L'invention se rapporte à une trousse pour solution chimique comportant un contenant de dissolution (2) rempli d'un liquide pour dissolution, un contenant chimique (3) rempli d'un produit chimique et un système de raccordement raccordant ces contenants. Cette trousse se caractérise en ce que le système de raccordement est constitué d'un élément de raccordement (4a) associé au contenant de dissolution, un élément de stockage du contenant pour produit chimique (4b) et un raccord (4c) permettant le passage d'un liquide et, lorsque l'élément de raccordement conçu pour le contenant de dissolution est séparé de l'élément de stockage du contenant pour produit chimique, un tuyau de passage de liquide (6) dans le raccord est ouvert de sorte que le produit chimique est mélangé au liquide pour dissolution. Il est ainsi possible d'obtenir une trousse chimique permettant de mélanger facilement un produit chimique et un liquide pour dissolution sans avoir recours à une aiguille de perforation.
PCT/JP2003/004490 2003-04-09 2003-04-09 Trousse pour solution chimique WO2004089273A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003236010A AU2003236010A1 (en) 2003-04-09 2003-04-09 Chemical solution kit
PCT/JP2003/004490 WO2004089273A1 (fr) 2003-04-09 2003-04-09 Trousse pour solution chimique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2003/004490 WO2004089273A1 (fr) 2003-04-09 2003-04-09 Trousse pour solution chimique

Publications (1)

Publication Number Publication Date
WO2004089273A1 true WO2004089273A1 (fr) 2004-10-21

Family

ID=33156446

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2003/004490 WO2004089273A1 (fr) 2003-04-09 2003-04-09 Trousse pour solution chimique

Country Status (2)

Country Link
AU (1) AU2003236010A1 (fr)
WO (1) WO2004089273A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2476037A (en) * 2009-12-08 2011-06-15 Kent Pharmaceuticals Ltd Medicament mixing containers

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0516117A2 (fr) * 1991-05-29 1992-12-02 Fujisawa Pharmaceutical Co., Ltd. Ensemble de récipient de liquide
JPH0810312A (ja) * 1994-04-28 1996-01-16 Otsuka Pharmaceut Factory Inc 輸液容器
EP0899203A1 (fr) * 1997-08-29 1999-03-03 L'oreal Ensemble de deux éléments montés libres en rotation l'un par rapport à l'autre de façon irréversible
JP2001151260A (ja) * 1999-11-30 2001-06-05 Yoshino Kogyosho Co Ltd 容器の注出キャップ

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0516117A2 (fr) * 1991-05-29 1992-12-02 Fujisawa Pharmaceutical Co., Ltd. Ensemble de récipient de liquide
JPH0810312A (ja) * 1994-04-28 1996-01-16 Otsuka Pharmaceut Factory Inc 輸液容器
EP0899203A1 (fr) * 1997-08-29 1999-03-03 L'oreal Ensemble de deux éléments montés libres en rotation l'un par rapport à l'autre de façon irréversible
JP2001151260A (ja) * 1999-11-30 2001-06-05 Yoshino Kogyosho Co Ltd 容器の注出キャップ

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2476037A (en) * 2009-12-08 2011-06-15 Kent Pharmaceuticals Ltd Medicament mixing containers

Also Published As

Publication number Publication date
AU2003236010A1 (en) 2004-11-01

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