WO2004003189A3 - Regulation of human phospholipase c-like protein - Google Patents

Regulation of human phospholipase c-like protein Download PDF

Info

Publication number
WO2004003189A3
WO2004003189A3 PCT/EP2003/006741 EP0306741W WO2004003189A3 WO 2004003189 A3 WO2004003189 A3 WO 2004003189A3 EP 0306741 W EP0306741 W EP 0306741W WO 2004003189 A3 WO2004003189 A3 WO 2004003189A3
Authority
WO
WIPO (PCT)
Prior art keywords
disorders
human phospholipase
protein
regulation
reagents
Prior art date
Application number
PCT/EP2003/006741
Other languages
French (fr)
Other versions
WO2004003189A2 (en
Inventor
Zhimin Zhu
Original Assignee
Bayer Healthcare Ag
Zhimin Zhu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag, Zhimin Zhu filed Critical Bayer Healthcare Ag
Priority to AU2003242759A priority Critical patent/AU2003242759A1/en
Publication of WO2004003189A2 publication Critical patent/WO2004003189A2/en
Publication of WO2004003189A3 publication Critical patent/WO2004003189A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reagents that regulate a novel human phospholipase C and reagents which bind to human phospholipase C gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cardiovascular disorders, gastrointestinal and liver disorders, cancer (particularly colon and colorectal cancer), hematological disorders, respiratory disorders (e.g., asthma and COPD), inflammatory disorders, musculo-skeletal disorders, neurological disorders, reproductive disorders, genitourinary disorders, and diabetes.
PCT/EP2003/006741 2002-06-26 2003-06-26 Regulation of human phospholipase c-like protein WO2004003189A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003242759A AU2003242759A1 (en) 2002-06-26 2003-06-26 Regulation of human phospholipase c-like protein

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US39141102P 2002-06-26 2002-06-26
US60/391,411 2002-06-26
US39969602P 2002-08-01 2002-08-01
US60/399,696 2002-08-01
US46000103P 2003-04-04 2003-04-04
US60/460,001 2003-04-04

Publications (2)

Publication Number Publication Date
WO2004003189A2 WO2004003189A2 (en) 2004-01-08
WO2004003189A3 true WO2004003189A3 (en) 2004-06-10

Family

ID=30003828

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/006741 WO2004003189A2 (en) 2002-06-26 2003-06-26 Regulation of human phospholipase c-like protein

Country Status (2)

Country Link
AU (1) AU2003242759A1 (en)
WO (1) WO2004003189A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6558400B2 (en) 2001-05-30 2003-05-06 Satiety, Inc. Obesity treatment tools and methods

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002026996A2 (en) * 2000-09-27 2002-04-04 Bayer Aktiengesellschaft Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002026996A2 (en) * 2000-09-27 2002-04-04 Bayer Aktiengesellschaft Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 17 May 1997 (1997-05-17), HIRATA: "Inositol-1, 4, 5-triphosphate binding protein", XP002256439, Database accession no. AAW01596 *
DATABASE EMBL [online] 4 August 1999 (1999-08-04), OHARA ET AL.: "Homo sapiens mRNA for KIAA1092 protein", XP002256440, Database accession no. AB029015 *
KOHNO TAKASHI ET AL: "Identification of a novel phospholipase C family gene at chromosome 2q33 that is homozygously deleted in human small cell lung carcinoma.", HUMAN MOLECULAR GENETICS, vol. 4, no. 4, 1995, pages 667 - 674, XP009018487, ISSN: 0964-6906 *
OTSUKI MAKIKO ET AL: "Identification and characterization of a new phospholipase C-like protein, PLC-L2.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 266, no. 1, 9 December 1999 (1999-12-09), pages 97 - 103, XP002256437, ISSN: 0006-291X *

Also Published As

Publication number Publication date
AU2003242759A8 (en) 2004-01-19
WO2004003189A2 (en) 2004-01-08
AU2003242759A1 (en) 2004-01-19

Similar Documents

Publication Publication Date Title
WO2004003189A3 (en) Regulation of human phospholipase c-like protein
AU2002250949A1 (en) Human g protein-coupled receptor
WO2004031375A3 (en) Regulation of human 3’, 5’ cyclic nucleotide phosphodiesterase pde1c
WO2004009803A3 (en) Regulation of human hepsin
WO2003000903A3 (en) Regulation of human nek-like serine/threonine protein kinase
WO2003033708A3 (en) Regulation of human serine/threonine protein kinase
WO2002092798A3 (en) Regulation of human phosphatidic acid phosphatase type 2c-like protein
WO2002006453A3 (en) Regulation of human desc1-like serine protease
WO2003000873A3 (en) Regulation of human serine/threonine protein kinase nek1
WO2003052088A3 (en) Regulation of human sialyltransferase
WO2002090543A3 (en) Regulation of human phosphatidic acid phosphatase type 2c-like protein
WO2003018815A3 (en) Regulation of human g protein-couple receptor kinase
WO2002099107A3 (en) Regulation of human trace amine receptor ta5
WO2003064469A3 (en) Regulation of human hematopoietin receptor-like protein
WO2003000874A3 (en) Regulation of human serine/threonine protein kinase nek3
WO2002055710A3 (en) Regulation of human purple acid phosphatase
WO2002062974A3 (en) Regulation of human elongase hselo1-like protein
WO2003018786A3 (en) Human serine/threonine kinase
WO2003035859A3 (en) Regulation of human serine/threonine kinase
WO2002057461A3 (en) Regulation of human adam-ts-like zinc metalloprotease
WO2002061058A3 (en) Regulation of human phospholipase
WO2002026996A3 (en) Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme
WO2002088362A3 (en) Regulation of human prostaglandin-f synthase 1-like protein
WO2002032938A3 (en) Regulation of human pgc-1-like protein
WO2002083887A3 (en) Regulation of human methionine aminopeptidase-like protein

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP