WO2002090543A3 - Regulation of human phosphatidic acid phosphatase type 2c-like protein - Google Patents

Regulation of human phosphatidic acid phosphatase type 2c-like protein Download PDF

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Publication number
WO2002090543A3
WO2002090543A3 PCT/EP2002/005044 EP0205044W WO02090543A3 WO 2002090543 A3 WO2002090543 A3 WO 2002090543A3 EP 0205044 W EP0205044 W EP 0205044W WO 02090543 A3 WO02090543 A3 WO 02090543A3
Authority
WO
WIPO (PCT)
Prior art keywords
acid phosphatase
phosphatidic acid
protein
phosphatase type
regulation
Prior art date
Application number
PCT/EP2002/005044
Other languages
French (fr)
Other versions
WO2002090543A2 (en
Inventor
Alex Smolyar
Original Assignee
Bayer Ag
Alex Smolyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Alex Smolyar filed Critical Bayer Ag
Priority to AU2002314048A priority Critical patent/AU2002314048A1/en
Publication of WO2002090543A2 publication Critical patent/WO2002090543A2/en
Publication of WO2002090543A3 publication Critical patent/WO2002090543A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reagents that regulate human phosphatidic acid phosphatase type 2c-like protein and reagents which bind to human phosphatidic acid phosphatase type 2c-like gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, cardiovascular disorders, CNS, COPD, asthma, and diabetes.
PCT/EP2002/005044 2001-05-09 2002-05-08 Regulation of human phosphatidic acid phosphatase type 2c-like protein WO2002090543A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002314048A AU2002314048A1 (en) 2001-05-09 2002-05-08 Regulation of human phosphatidic acid phosphatase type 2c-like protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28955101P 2001-05-09 2001-05-09
US60/289,551 2001-05-09

Publications (2)

Publication Number Publication Date
WO2002090543A2 WO2002090543A2 (en) 2002-11-14
WO2002090543A3 true WO2002090543A3 (en) 2003-12-18

Family

ID=23112018

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/005044 WO2002090543A2 (en) 2001-05-09 2002-05-08 Regulation of human phosphatidic acid phosphatase type 2c-like protein

Country Status (2)

Country Link
AU (1) AU2002314048A1 (en)
WO (1) WO2002090543A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003202543A1 (en) * 2002-01-07 2003-07-24 Bayer Aktiengesellschaft Human phosphatidic acid phosphatase type 2-like protein

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055163A1 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2002010363A2 (en) * 2000-07-28 2002-02-07 Incyte Genomics, Inc. Protein phosphatases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001055163A1 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2002010363A2 (en) * 2000-07-28 2002-02-07 Incyte Genomics, Inc. Protein phosphatases

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 March 2001 (2001-03-01), XP002234282, Database accession no. Q9H4Z9 *
DATABASE EMBL [online] 4 December 2001 (2001-12-04), XP002234306, Database accession no. AAS34812 *
DATABASE EMBL [online] 8 February 2001 (2001-02-08), XP002234283, Database accession no. AK014763 *
DATABASE EMBL [online] 9 November 1999 (1999-11-09), XP002234284, Database accession no. AW157233; *
HOOKS S B ET AL: "Identification of a novel human phosphatidic acid phosphatase type 2 isoform", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 427, no. 2, 8 May 1998 (1998-05-08), pages 188 - 192, XP002221015, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
WO2002090543A2 (en) 2002-11-14
AU2002314048A1 (en) 2002-11-18

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