WO2002083887A3 - Regulation of human methionine aminopeptidase-like protein - Google Patents

Regulation of human methionine aminopeptidase-like protein Download PDF

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Publication number
WO2002083887A3
WO2002083887A3 PCT/EP2002/004079 EP0204079W WO02083887A3 WO 2002083887 A3 WO2002083887 A3 WO 2002083887A3 EP 0204079 W EP0204079 W EP 0204079W WO 02083887 A3 WO02083887 A3 WO 02083887A3
Authority
WO
WIPO (PCT)
Prior art keywords
methionine aminopeptidase
protein
human methionine
regulation
reagents
Prior art date
Application number
PCT/EP2002/004079
Other languages
French (fr)
Other versions
WO2002083887A2 (en
Inventor
Alex Smolyar
Original Assignee
Bayer Ag
Alex Smolyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Alex Smolyar filed Critical Bayer Ag
Priority to AU2002308139A priority Critical patent/AU2002308139A1/en
Publication of WO2002083887A2 publication Critical patent/WO2002083887A2/en
Publication of WO2002083887A3 publication Critical patent/WO2002083887A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents that regulate human methionine aminopeptidase-like protein and reagents which bind to human methionine aminopeptidase-like gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, cardiovascular disorders, diabetis, metabolic diseases, CNS disorders, and COPD.
PCT/EP2002/004079 2001-04-12 2002-04-12 Regulation of human methionine aminopeptidase-like protein WO2002083887A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002308139A AU2002308139A1 (en) 2001-04-12 2002-04-12 Regulation of human methionine aminopeptidase-like protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28315201P 2001-04-12 2001-04-12
US60/283,152 2001-04-12

Publications (2)

Publication Number Publication Date
WO2002083887A2 WO2002083887A2 (en) 2002-10-24
WO2002083887A3 true WO2002083887A3 (en) 2003-12-04

Family

ID=23084754

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/004079 WO2002083887A2 (en) 2001-04-12 2002-04-12 Regulation of human methionine aminopeptidase-like protein

Country Status (2)

Country Link
AU (1) AU2002308139A1 (en)
WO (1) WO2002083887A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006010516A1 (en) * 2004-07-29 2006-02-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with methionine aminopeptidase 2 like protein (metap2-like)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001042467A2 (en) * 1999-12-08 2001-06-14 Millennium Pharmaceuticals, Inc. Genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
WO2001053312A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Novel nucleic acids and polypeptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001042467A2 (en) * 1999-12-08 2001-06-14 Millennium Pharmaceuticals, Inc. Genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
WO2001053312A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
ARFIN STUART M ET AL: "Eukaryotic methionyl aminopeptidases: Two classes of cobalt-dependent enzymes.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 92, no. 17, 1995, 1995, pages 7714 - 7718, XP002242334, ISSN: 0027-8424 *
DATABASE EMBL [online] EBI, Hinxton, Cambridgeshire, U.K.; 6 August 2001 (2001-08-06), SCHLEGEL R. ET AL: "Sequence 3916 from Patent WO0142467.", XP002242335, Database accession no. AX188221 *
DATABASE EMBL [online] EBI, HInxton, Cambridgeshire, U.K.; 8 February 2001 (2001-02-08), ADACHI J ET AL: "Mus musculus adult male cerebellum cDNA, RIKEN full-length enriched library, clone:1500015B04 product:methionine aminopeptidase-like 1, full insert sequence.", XP002242341, Database accession no. AK005241 *
DATABASE EMBL [online] EBI, Hinxton, Cambridgeshire, U.K.; 8 February 2001 (2001-02-08), ADACHI J ET AL: "Mus musculus adult male tongue cDNA, RIKEN full-length enriched library, clone:2310066F24 product:methionine aminopeptidase-like 1, full insert sequence.", XP002242342, Database accession no. AK010067 *
DATABASE GENESEQ [online] EBI, HInxton, Cambridgeshire, U.K.; 19 September 2001 (2001-09-19), SCHLEGEL R ET AL: "Human cervical cancer marker nucleic acid 3913.", XP002242336, Database accession no. AAH72639 *
DATABASE GENESEQ [online] EBI, Hinxton, Cambridgeshire, U.K.; 22 October 2001 (2001-10-22), TANG YT ET AL: "Human polynucleotide SEQ ID NO 4268.", XP002242339, Database accession no. AAI60279 *
DATABASE GENESEQ [online] EBI, Hinxton, Cambridgeshire, U.K.; 22 October 2001 (2001-10-22), TANG YT ET AL: "Human polynucleotide SEQ ID NO 696.", XP002242337, Database accession no. AAI58493 *
DATABASE GENESEQ [online] EBI, Hinxton, Cambridgeshire, U.K.; 22 October 2001 (2001-10-22), TANG YT ET AL: "Human polypeptide SEQ ID NO 2482.", XP002242338, Database accession no. AAM39337 *
DATABASE GSP [online] EBI, Hinxton, Cambridgeshire, U.K.; 22 October 2001 (2001-10-22), TANG YT ET AL: "Human polypeptide SEQ ID NO 6054.", XP002242340, Database accession no. AAM41123 *
DATABASE SWISSPROT [online] EBI, Hinxton, Cambridgeshire, U.K.; 1 October 1996 (1996-10-01), NAGASE T ET AL: "Methionine aminopeptidase 1 (EC 3.4.11.18) (MetAP 1) (Peptidase M 1)", XP002242343, Database accession no. P53582 *

Also Published As

Publication number Publication date
AU2002308139A1 (en) 2002-10-28
WO2002083887A2 (en) 2002-10-24

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