WO2002033056A3 - Regulation of human serine-threonine protein kinase - Google Patents

Regulation of human serine-threonine protein kinase Download PDF

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Publication number
WO2002033056A3
WO2002033056A3 PCT/EP2001/011892 EP0111892W WO0233056A3 WO 2002033056 A3 WO2002033056 A3 WO 2002033056A3 EP 0111892 W EP0111892 W EP 0111892W WO 0233056 A3 WO0233056 A3 WO 0233056A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein kinase
threonine protein
human serine
regulation
reagents
Prior art date
Application number
PCT/EP2001/011892
Other languages
French (fr)
Other versions
WO2002033056A2 (en
Inventor
Rainer H Koehler
Original Assignee
Bayer Ag
Rainer H Koehler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Rainer H Koehler filed Critical Bayer Ag
Priority to AU2002220630A priority Critical patent/AU2002220630A1/en
Publication of WO2002033056A2 publication Critical patent/WO2002033056A2/en
Publication of WO2002033056A3 publication Critical patent/WO2002033056A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Reagents which regulate human serine-threonine protein kinase and reagents which bind to human serine-threonine protein kinase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, CNS disorders, obesity, diabetes, asthma, and COPD.
PCT/EP2001/011892 2000-10-16 2001-10-15 Regulation of human serine-threonine protein kinase WO2002033056A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002220630A AU2002220630A1 (en) 2000-10-16 2001-10-15 Regulation of human serine-threonine protein kinase

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24009700P 2000-10-16 2000-10-16
US60/240,097 2000-10-16
US30809601P 2001-07-30 2001-07-30
US60/308,096 2001-07-30

Publications (2)

Publication Number Publication Date
WO2002033056A2 WO2002033056A2 (en) 2002-04-25
WO2002033056A3 true WO2002033056A3 (en) 2003-03-13

Family

ID=26933142

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011892 WO2002033056A2 (en) 2000-10-16 2001-10-15 Regulation of human serine-threonine protein kinase

Country Status (2)

Country Link
AU (1) AU2002220630A1 (en)
WO (1) WO2002033056A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0406427D0 (en) 2004-03-22 2004-04-21 Health Prot Agency Biological indicator
US7901885B2 (en) 2006-05-09 2011-03-08 Dsm Ip Assets B.V. Genes and markers in type 2 diabetes and obesity

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034228A (en) * 1998-12-15 2000-03-07 Zeneca Limited Human signal transduction serine/threonine kinase
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases
WO2001046397A2 (en) * 1999-12-23 2001-06-28 Incyte Genomics, Inc. Human kinases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6034228A (en) * 1998-12-15 2000-03-07 Zeneca Limited Human signal transduction serine/threonine kinase
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases
WO2001046397A2 (en) * 1999-12-23 2001-06-28 Incyte Genomics, Inc. Human kinases

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EMBL; 1 July 1995 (1995-07-01), HILLIER L ET AL.: "ym34g06.r1 Soares infant brain 1NIB Homo sapiens cDNA clone IMAGE:50231 5' similar to SP:PKD1_DICDI P34100 DEVELOPMENTALLY REGULATED PROTEIN KINASE 1 ;, mRNA sequence.", XP002211512, Database accession no. H16883 *
DATABASE EMBL [online] EMBL; 17 February 1995 (1995-02-17), GENEXPRESS: "H. sapiens partial cDNA sequence; clone c-2hf04.", XP002211511, Database accession no. F07785 *
DATABASE EMBL [online] EMBL; 3 March 2000 (2000-03-03), STROM T M: "Homo sapiens gene for serine/threonine protein kinase", XP002211515, Database accession no. AJ250839 *
DATABASE EMBL [online] EMBL; 30 April 2000 (2000-04-30), HASHIMOTO K ET AL.: "Mus musculus brain cDNA, clone MNCb-1563, similar to AJ250840 serine/threonine protein kinase (Mus musculus).", XP002211514, Database accession no. AB041542 *
DATABASE EMBL [online] EMBL; 7 January 2000 (2000-01-07), NIH-MGC: "2822918.5prime NIH_MGC_7 Homo sapiens cDNA clone 2822918 5', mRNA sequence.", XP002211513, Database accession no. AW245503 *

Also Published As

Publication number Publication date
AU2002220630A1 (en) 2002-04-29
WO2002033056A2 (en) 2002-04-25

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