WO2003052088A3 - Regulation of human sialyltransferase - Google Patents

Regulation of human sialyltransferase Download PDF

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Publication number
WO2003052088A3
WO2003052088A3 PCT/EP2002/014360 EP0214360W WO03052088A3 WO 2003052088 A3 WO2003052088 A3 WO 2003052088A3 EP 0214360 W EP0214360 W EP 0214360W WO 03052088 A3 WO03052088 A3 WO 03052088A3
Authority
WO
WIPO (PCT)
Prior art keywords
human sialyltransferase
regulation
reagents
sialyltransferase
human
Prior art date
Application number
PCT/EP2002/014360
Other languages
French (fr)
Other versions
WO2003052088A2 (en
Inventor
Alex Smolyar
Original Assignee
Bayer Healthcare Ag
Alex Smolyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag, Alex Smolyar filed Critical Bayer Healthcare Ag
Priority to AU2002352253A priority Critical patent/AU2002352253A1/en
Publication of WO2003052088A2 publication Critical patent/WO2003052088A2/en
Publication of WO2003052088A3 publication Critical patent/WO2003052088A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reagents that regulate human sialyltransferase and reagents which bind to human sialyltransferase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, diabetes, cancer, CNS disorders, cardiovascular disorders, COPD, and asthma.
PCT/EP2002/014360 2001-12-18 2002-12-17 Regulation of human sialyltransferase WO2003052088A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002352253A AU2002352253A1 (en) 2001-12-18 2002-12-17 Regulation of human sialyltransferase

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US34026201P 2001-12-18 2001-12-18
US60/340,262 2001-12-18
US39384402P 2002-07-08 2002-07-08
US60/393,844 2002-07-08

Publications (2)

Publication Number Publication Date
WO2003052088A2 WO2003052088A2 (en) 2003-06-26
WO2003052088A3 true WO2003052088A3 (en) 2004-03-04

Family

ID=26992040

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/014360 WO2003052088A2 (en) 2001-12-18 2002-12-17 Regulation of human sialyltransferase

Country Status (2)

Country Link
AU (1) AU2002352253A1 (en)
WO (1) WO2003052088A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7374118B2 (en) 2017-12-18 2023-11-06 ザ ジェネラル ホスピタル コーポレイション Glycan modification

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2019864B1 (en) * 2006-05-24 2011-07-13 Université de Provence (Aix-Marseille 1) Preparation and uses of gene sequences encoding chimerical glycosyltransferases with optimized glycosylation activity
KR20200113556A (en) * 2019-03-25 2020-10-07 황인후 Composition for preventing or treating diabetes and method for screening antidiabetic agents using ST8SIA1

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994012646A1 (en) * 1992-11-27 1994-06-09 Ciba-Geigy Ag Proteins having glycosyltransferase activity

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994012646A1 (en) * 1992-11-27 1994-06-09 Ciba-Geigy Ag Proteins having glycosyltransferase activity

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE SWALL [online] 1 December 2001 (2001-12-01), XP002246532, Database accession no. Q96HE4 *
DATABASE SWALL [online] 1 December 2001 (2001-12-01), XP002246533, Database accession no. Q96JF0 *
KUROSAWA N ET AL: "Molecular cloning and expression of chick embryo Gal beta 1,4GlcNAc alpha 2,6-sialyltransferase. Comparison with the mammalian enzyme", EUROPEAN JOURNAL OF BIOCHEMISTRY, BERLIN, DE, vol. 219, no. 1/2, 15 January 1994 (1994-01-15), pages 375 - 381, XP002101174, ISSN: 0014-2956 *
NAGASE T ET AL: "PREDICTION OF THE CODING SEQUENCES OF UNIDENTIFIED HUMAN GENES XX. THE COMPLETE SEQUENCES OF 100 NEW CDNA CLONES FROM BRAIN WHICH CODE FOR LARGE PROTEINS IN VITRO", DNA RESEARCH, UNIVERSAL ACADEMY PRESS, JP, vol. 8, no. 2, 2001, pages 85 - 95, XP002943489, ISSN: 1340-2838 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7374118B2 (en) 2017-12-18 2023-11-06 ザ ジェネラル ホスピタル コーポレイション Glycan modification

Also Published As

Publication number Publication date
AU2002352253A1 (en) 2003-06-30
AU2002352253A8 (en) 2003-06-30
WO2003052088A2 (en) 2003-06-26

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