WO2003100144A1 - Fibre composite ame-gaine biocompatible, fibre synthetique biocompatible et procede de production - Google Patents

Fibre composite ame-gaine biocompatible, fibre synthetique biocompatible et procede de production Download PDF

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Publication number
WO2003100144A1
WO2003100144A1 PCT/JP2003/006438 JP0306438W WO03100144A1 WO 2003100144 A1 WO2003100144 A1 WO 2003100144A1 JP 0306438 W JP0306438 W JP 0306438W WO 03100144 A1 WO03100144 A1 WO 03100144A1
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Prior art keywords
thermoplastic synthetic
biocompatible
synthetic polymer
silk
fiber
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PCT/JP2003/006438
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English (en)
Japanese (ja)
Inventor
Kozo Tsubouchi
Hideki Ishikawa
Original Assignee
National Institute Of Agrobiological Sciences
Shinwa Corp.
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Application filed by National Institute Of Agrobiological Sciences, Shinwa Corp. filed Critical National Institute Of Agrobiological Sciences
Priority to AU2003242411A priority Critical patent/AU2003242411A1/en
Publication of WO2003100144A1 publication Critical patent/WO2003100144A1/fr

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    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F8/00—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof
    • D01F8/04—Conjugated, i.e. bi- or multicomponent, artificial filaments or the like; Manufacture thereof from synthetic polymers
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F1/00—General methods for the manufacture of artificial filaments or the like
    • D01F1/02—Addition of substances to the spinning solution or to the melt
    • D01F1/10—Other agents for modifying properties
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F6/00—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof
    • D01F6/44—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds
    • D01F6/46—Monocomponent artificial filaments or the like of synthetic polymers; Manufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polyolefins

Definitions

  • the present invention relates to a synthetic fiber produced from a thermoplastic synthetic polymer containing silk powder, and particularly to a synthetic fiber having excellent biocompatibility and excellent durability and moldability.
  • silk has an extremely high gloss and soft texture, and also has excellent moisture absorption and desorption properties.Therefore, it cannot be used as a high-grade clothing material. It can be called a material.
  • the surface of products such as synthetic fibers, non-woven fabrics and films may contain silk proteins.
  • a method of imparting silk properties by chemically modifying it with a treating agent, a method of adding silk powder to a thermoplastic synthetic polymer, and imparting the properties of silk to a molded article of the thermoplastic synthetic polymer, etc. has been proposed.
  • a silk protein aqueous solution in which the surface of a product such as synthetic fiber, non-woven fabric, or film is chemically modified with a silk protein-containing treating agent to impart silk properties, a silk protein aqueous solution (A) is, for example,
  • Examples of using a dispersion of a silk protein aqueous solution with a binder added as a treating agent include:
  • examples of using a mixture of silk powder with a binder or paint as a treating agent include: For example,
  • the properties of silk protein can be generally imparted to the material surface, but in the method using a silk protein aqueous solution (dispersion solution) as a treating agent, silk protein uses fibers. It has the drawback that it easily falls off during or during cleaning and has poor durability.
  • Silk fabric has no thermoplastic properties and will decompose and carbonize until heated when heated, but as mentioned earlier, silk has excellent luster, texture, moisture absorption, moisture absorption, etc. In particular, it has biocompatibility as a property not found in thermoplastic synthetic polymers.
  • silk protein has the property of promoting the growth of human-derived skin cells as one of the functions of biocompatibility.
  • the silk protein in the method in which the silk protein is contained in the thermoplastic synthetic polymer, the loss of the silk protein during use or washing is reduced, but the contained silk protein becomes a mechanical weak point. However, it causes a decrease in the strength of the fiber.
  • thermoplastic synthetic polymer examples include, for example,
  • Japanese Patent Application Laid-Open No. H10-212124 / 17 discloses that the surface of a silk powder having an average particle diameter of 20 to 50 ⁇ m has an average particle diameter of 0.2 to improve the heat resistance of the silk powder. M0.3 m of titanium oxide was pressed and adhered, mixed with thermoplastic resin, spun at a spinning temperature of 270 ° C, and the titanium oxide-containing silk powder was evenly distributed in the fiber. Can get synthetic fiber Points are shown.
  • the fiber used for ordinary clothes has a diameter of 100 m or less, especially 30 m or less.
  • the presence of silk powder having a large average particle diameter of 20 to 50 m significantly lowers the tensile strength of the fibers, making them virtually unusable as fibers. You can only get what you can.
  • the above spinning temperature of 270 ° C is much higher than the decomposition temperature of silk protein, and at such a temperature, the silk protein is carbonized, so that the original characteristics of silk protein can be utilized. There is a problem that you can not.
  • An object of the present invention is to provide a new material excellent in biocompatibility, particularly a fiber, which has a silky luster, texture, moisture retention and the like, and is mainly composed of a thermoplastic synthetic polymer.
  • Another object of the present invention is to provide a new biocompatible material that can withstand practical use with a small decrease in the strength of the synthetic fiber even when the synthetic fiber made of a thermoplastic synthetic polymer contains silk powder. .
  • the present invention also develops a low-cost fiber having both functions by using a high-priced biocompatible silk protein and a low-priced thermoplastic synthetic polymer having excellent durability and moldability.
  • the purpose is to: Disclosure of the invention
  • thermoplastic synthetic polymer As a result of extensive research into obtaining biocompatible synthetic fibers that can fully demonstrate the properties of the silk protein and that are durable, as a result of at least the core-sheath structure and silk powder The present inventors have found that the particle size and the melting point of the thermoplastic synthetic polymer are important factors, and have completed the present invention based on this finding.
  • the core material is made of a thermoplastic synthetic polymer
  • the sheath material is a silk powder substantially free from powder particles having a particle diameter exceeding 10 ⁇ m, and the melting point is 200 °. It is a biocompatible core-sheath composite fiber made of a thermoplastic synthetic polymer of C or less.
  • thermoplastic synthetic polymer constituting the core material and the thermoplastic synthetic polymer constituting the sheath material are present in the same thermoplastic synthetic polymer as the biocompatible core-sheath composite fiber.
  • thermoplastic synthetic polymer constituting the core material and the thermoplastic synthetic polymer constituting the sheath material are present in biocompatible core-sheath type composite fibers which are different thermoplastic synthetic polymers.
  • the powder is made of a silk powder substantially free of particles having a particle diameter exceeding 10 m and a thermoplastic synthetic polymer having a melting point of 200 ° C. or less. Present in synthetic fibers.
  • thermoplastic synthetic polymer is an olefin polymer
  • a biocompatible core-sheath composite fiber or a biocompatible synthetic fiber having a fiber diameter of 5 to 100 m, preferably 10 to 30 m.
  • a biocompatible core-sheath composite fiber obtained by subjecting a core material made of a thermoplastic synthetic polymer and a sheath material made of silk powder and a thermoplastic synthetic polymer to core-sheath composite spinning and stretching. Lies in the manufacturing method.
  • a core material comprising a thermoplastic synthetic polymer; a silk powder substantially free from powder particles having a particle diameter of more than 10 ⁇ m; and a thermoplastic material having a melting point of 200 ° C. or less.
  • the present invention relates to a method for producing a biocompatible core-in-sheath type composite fiber in which a sheath material made of a synthetic polymer is subjected to core-sheath composite spinning and stretching.
  • a powder having substantially no particle diameter exceeding 10 nm, a silk powder substantially free from particles, and a thermoplastic synthetic polymer having a melting point of 200 ° C. or less are mixed, heated and kneaded. And then spinning and stretching.
  • the present invention also employs a configuration combining two or more selected from the above 1 to 5, 6 to 8, 9 to 11, and 12 to 15 as long as the purpose is met. It is possible.
  • the biocompatible core-sheath type composite fiber and the biocompatible synthetic fiber of the present invention have silk-like luster, texture, moisturizing property, etc., and are excellent in durability, and are suitable for clothing materials and medical materials. Useful. BRIEF DESCRIPTION OF THE FIGURES
  • FIG. 1 is a photomicrograph of the double-layered fiber of Example 3 of the present invention.
  • FIG. 2 shows a polarizing microscopic photograph of a fiber having a two-layer structure of Example 3 of the present invention.
  • the raw material of silk protein is cocoon thread, raw silk, silk woven or knitted fabric, silk thread (fiproin fiber), their remaining yarn or their unscrambled, semi-scrambled, refined It can be applied to kneaded materials, and fibers, powders, films, etc. made from them, protein fibers spun by silkworms such as silkworms and wild silkworms, and all of their remnants.
  • Liquid silk consists of fibrin and sericin (these are called silk powders), and liquid fiber mouth has a molecular weight of about 370,000 [Tasiro Yutak and Otsuki Eiichi, Journal of Cell Biology, Vol. 46, P. 1 (1
  • a fiber mouth with a molecular weight of about 370,000 is divided into a molecular weight of about 350,000 (H chain) and about 25,000 (L chain).
  • Cocoons (consisting of so-called cocoons and pupae) are formed when silkworms spit liquid silk during cocoon production.
  • cocoon contains fibrin at the center and sericin around it, and the abundance ratio is (70-80% fibrous mouth): 30-20% (sericin). Have been.
  • raw silk is made by assembling several to several tens of cocoons, and a woven fabric made of raw silk is called raw woven.
  • the process of removing sericin from cocoon, raw silk or raw weave is called scouring, and the fibers after scouring are silk or fiproin fibers.
  • the silk thread is produced by first drying the grown cocoon and then winding it after boiled cocoon to produce raw silk.
  • raw silk or raw weave is refined to obtain silk yarn or silk fabric.
  • the waste generated in these steps is the residual yarn.
  • Crystalline silk powder The crystalline silk powder is produced, for example, according to a method for producing a crystalline silk ultrafine powder as disclosed in JP-A-2001-48989.
  • the particle size of silk powder is generally represented by the average particle size, but there is a distribution in the particle size, and the size of the powder is such that particles having a smaller average particle size and larger particles are widely distributed.
  • the average particle diameter is also focused on the value of the maximum particle diameter in consideration of the fact that the larger the powder, the lower the tensile strength.
  • the desired silk powder-containing resin cannot be spun, especially drawn.
  • the powder obtained by the production method of the aforementioned Japanese Patent Application Laid-Open No. 2001-48989 is pulverized and classified to obtain a powder having a particle diameter of more than 10 m, more preferably 5 i / Those exceeding m are separated and removed.
  • powders having a particle size of more than 10 ⁇ m, more preferably powders having a particle size of more than 5 ⁇ m are not included.
  • the particle diameter is preferably 110 or less of the fiber diameter (that is, the fiber formed by spinning and drawing).
  • the powder is likely to be buried in the fiber, and it is true that the buried powder does not function as a silk powder.
  • the particle diameter of the powder is preferably 0.1 m or more, and more preferably 0.5 / m or more.
  • the diameter of the silk powder is preferably 0.5 m or more and 5 m or less.
  • Non-crystalline silk powder is disclosed in Japanese Patent Application Laid-Open No. 11-170160 (Wound dressing material containing silk fiplin and silk sericin as a main component and a method for producing the same). — 1 639 9 9 (Method of producing functional silk fiproin and its use), Japanese Patent Application Laid-Open No. 2002-122628 (1) Sericin-containing material, method of its production and It is manufactured according to a method such as that described in Japanese Patent Application No. 2001-180169 (a method for producing and using a functional polypeptide derived from silk fibrin).
  • the non-crystalline silk powder is also crushed and classified like the above-mentioned crystalline silk powder to obtain a powder having a particle diameter of more than 10 ⁇ m, preferably a powder having a particle diameter of more than 5 removed.
  • the minimum particle size of the powder is preferably 0.1 m or more, more preferably 0.5 / m or more.
  • the maximum particle size of the powder does not substantially include a powder having a particle size exceeding 10 m, and more preferably does not include a powder having a particle size exceeding 5 ⁇ m. To do.
  • particles of 10 ⁇ m or more may be included, but the degree does not matter.
  • the minimum particle diameter of the powder is preferably 0.1 m or more, more preferably 0.5 m or more, as described above, from the viewpoint of being easily buried in the fiber. .
  • the biocompatibility of the silk powder in the present invention means that the silk powder does not adversely affect the growth of human skin cells.
  • Such silk powder is said to be excellent in biocompatibility, it is easily decomposed by heat, light, acid, alkali, etc., and its molecular weight is reduced. Incidentally, such a decrease in molecular weight leads to a decrease in the viability of human cells, and an extremely decrease in the molecular weight also causes inhibition of cell growth.
  • thermoplastic synthetic polymer constituting the biocompatible core-sheath type composite fiber or the biocompatible synthetic fiber of the present invention
  • examples of the thermoplastic synthetic polymer constituting the biocompatible core-sheath type composite fiber or the biocompatible synthetic fiber of the present invention include polyethylene (PE) and polypropylene (melting point: 200 ° C. or less).
  • Polyolefin-based (co) polymers such as PP) and aliphatic polyesters can be used.
  • polyethylene-based copolymer examples include a copolymer of ethylene and —olefin having 3 to 20 carbon atoms, an ethylene-acrylic acid ester copolymer, and a copolymer of ethylene and ⁇ -carbon having 3 to 20 carbon atoms.
  • comonomer «— olefins examples include propylene, butene
  • comonomer ⁇ -olefins may be used alone or in combination of two or more.
  • Aliphatic polyesters include polylactic acid, poly-3-hydroxypropionate, poly-3-hydroxybutyrate, poly-13-hydroxybutyrate, poly- ⁇ -force prolact Among them, polylactic acid, which is a biodegradable polymer, is particularly preferred.
  • the lower limit of the melting point of the aliphatic polyester is 70 ° C. from the viewpoint of ensuring sufficient heat resistance and maintaining good spinnability.
  • polyesters such as polyethylene phthalate and polyethylene terephthalate
  • condensation polymers such as nylon and polyurethane may be added with other low-softening point polymers and plasticizers. It can be used as a polymer composition having a softening point of 0 ° C or less.
  • thermoplastic synthetic polymers may include, if necessary, antibacterial agents, antifungal agents, light stabilizers such as ultraviolet absorbers and infrared absorbers, antioxidants, dewatering agents, and antistatic agents.
  • antibacterial agents such as ultraviolet absorbers and infrared absorbers
  • light stabilizers such as ultraviolet absorbers and infrared absorbers
  • antioxidants such as antioxidants, dewatering agents, and antistatic agents.
  • Various additives such as a flame retardant, a colorant, a dye, and a conductive agent may be contained.
  • a pellet is made by mixing silk powder and a thermoplastic synthetic polymer.
  • the mixing ratio of the silk powder (the weight ratio of the thermoplastic synthetic polymer of the silk powder) is 5 to 50% by weight, preferably 10 to 30% by weight.
  • the weight percentage of silk powder is If it is more than 50% by weight, it is difficult to mix with each other at the time of mixing, so that kneading cannot be performed.
  • the proportion of the silk powder is less than about 5% by weight, the function of the silk powder does not work sufficiently.
  • spinning method examples include a wet spinning method, a dry spinning method, and a melt spinning method. In the present invention, it is desirable to use a melt spinning method.
  • thermoplastic synthetic polymers have the appropriate spinning temperature, respectively.Since silk powder is too hot, it decomposes to lower molecular weight, so it has a lower melting point than PE and PP among thermoplastic synthetic polymers.
  • the resin is particularly desirable.
  • thermoplastic synthetic polymer In spinning a thermoplastic synthetic polymer, the heat of the spinning solution causes decomposition of the silk powder.
  • the yellowed or brownish silk powder inhibits human skin cell growth.
  • the maximum temperature is usually about 3 to 6 minutes, so it is preferable to adopt a temperature range that does not cause any problem even if heating is performed for at least 6 minutes.
  • Silk powder adversely affects human skin cell growth due to melting and heating during spinning The effect begins when the heat treatment is performed at a temperature not exceeding 200 ° C, which is a temperature range in which heating for 6 minutes does not cause any problem.
  • thermoplastic synthetic polymer having a melting point of 200 ° C. or less is preferable.
  • the temperature is low, yellowing and thermal decomposition can be avoided. For example, it is about 20 minutes at 180 ° C and about 60 minutes at 150 ° C.
  • the fiber having a double-layered structure having a core and a sheath maintains the tensile strength and is made of silk. This enabled the powder to be localized near the fiber surface.
  • the tensile strength of the fiber can be sufficiently borne by the core, and the decrease in strength due to the inclusion of the silk powder can be minimized.
  • a silk powder containing no powder particles exceeding at least 10 ⁇ m it is preferable to use a silk powder containing no powder particles exceeding at least 10 ⁇ m.
  • a silk powder containing no powder particles of at least 10 m it is preferable to use a silk powder containing no powder particles of at least 10 m.
  • the silk powder in the sheath portion is more Localization is more effective because it comes to the surface.
  • the silk powder is physically retained by being immobilized on the surface of the fiber by the thermoplastic synthetic polymer and does not fall off during use.
  • a pellet is prepared by mixing a thermoplastic synthetic polymer and silk powder, and this pellet is used as a sheath, and is spun at the same time as the core thermoplastic synthetic polymer.
  • the diameter of the synthetic fiber is a + 2b when the diameter of the core is a and the thickness corresponding to the sheath is, but the ratio of a to 2b is 5 ⁇ 95 to 95-5, preferably 30-80 to 70-20.
  • thermoplastic synthetic polymers of the core and sheath may be the same or different.
  • the silkworm silk is boiled for one hour in a 0.1% aqueous sodium carbonate solution 50 times the volume of the silkworm and refined to obtain fibrin fibers (silk thread). g, add 5 g of sodium carbonate, and add approximately 120 ° C (2 Pressure) for 2 hours, washed with water and dried.
  • this silk material is ground with a stirring and crushing device (Ishikawa type), and then crushed with a rotary impact crusher [Sample Mill KI-1 manufactured by Fuji Electric Industries Co., Ltd.]. It was pulverized with a current grinder [current jet CJ-10 manufactured by Nisshin Flour Milling Co., Ltd.].
  • the obtained silk powder (A) was distributed in the range of 0.3 ⁇ m to 9.3 ⁇ , and the average particle size was 3.2 ⁇ m.
  • the silk powder (B) was distributed from 0.8 ⁇ m to 4.6 ⁇ m, and the average particles were The diameter was 2.5 / m.
  • the silk powder (B) obtained in Example 1 was subjected to dry heat treatment.
  • Dry heat treatment was performed using Clsuzu Manufacturing (Thenno-Regulator)] at (2) 180 ° C and (3) 190. C, (4) 200 ° C, (5) 210. At each temperature of C, the silk powder placed in a petri dish was placed for 6 minutes and subjected to a dry heat treatment.
  • the silk powder dried and heat-treated at 210 ° C. turned yellow.
  • the powder not subjected to the dry heat treatment was (1) brought to room temperature.
  • the cell viability of (1) to (5) was measured as follows. 0.5 mg of each of the silk powders (1) to (5) was placed in a 2 ml cell culture medium, and about 70,000 cells were inoculated into the medium and cultured for 3 days.
  • the cells used were normal human adult skin fibroblasts [KF-410 (Kurashiki Spinning Co., Ltd.)], and the medium used was a low serum freezing medium for fibroblast proliferation [M edium 106 S, LSGS, PSA solution (manufactured by Kurashiki Boseki Co., Ltd.)] was used.
  • Cultivation is performed on a single culture dish containing the silk powder of (1) to (5). 2 ml of the culture medium was added, and 70,000 cells were inoculated therein and cultured for 3 days.
  • the number of cells was determined by adding 2 ml of medium and 0.1 ml of Alama Blue (IWAKI) per dish to the plate, and calculating the absorbance at 570 nm and 600 nm after 2 hours at 37 ° C. The amount of reduction was defined as the number of viable cells.
  • IWAKI Alama Blue
  • a petri dish without silk powder was used as a control (100%), and the cell growth number of the petri dish with silk powder was measured. The results are shown in Table 1.
  • the silk powder has cell viability in the untreated state (1), but the cell viability decreases as the temperature of the dry heat treatment increases, and at 200 ° C., the cell viability almost disappears. At 210 ° C, cell viability is rather inhibited.
  • Table 1 shows the relationship between the dry heat treatment temperature of silk powder and the cell growth rate.
  • the silk powder (B) of Example 1 was put into a PE together with a plasticizer, and the mixture was applied to the silk powder and PE at 145 ° C and 25 minutes using Laboplastomil [Toyo Seiki Seisakusho]. Was kneaded and kneaded to produce spinning chips.
  • the weight ratio of silk powder to PE in this chip is 2 to 8.
  • unstretched yarn was prepared by spinning such that PP became the core and PE containing the silk powder became the sheath.
  • the undrawn yarn is drawn at room temperature to about 4 times the length (drawn yarn, see Fig. 1)
  • the portion that appears to be small and shiny is the silk powder, and it can be seen that the silk powder is localized near the fiber surface (see Fig. 2).
  • the tensile strength of the drawn fiber was about 11.5 that of the PE / PP double-layered fiber when the silk powder was not mixed.
  • Silk powder is often buried in the unstretched sheath.
  • the undrawn yarn becomes thinner by drawing (the thickness of the sheath becomes thinner), but since the silk powder is not drawn, the silk powder buried in the sheath resin is retained on the resin and remains on the fiber surface. Appear.
  • the resin of the sheath is partially divided by the silk powder in the fiber axis direction (arrow in FIG. 1), and in this case, the fiber itself has a unique touch. Some powders appear on the fiber surface.
  • FIG. 1 shows a micrograph of a double-layered fiber containing silk powder in a sheath.
  • FIG. 2 is a polarizing microscope photograph.
  • the core-sheath fiber (B) of PPZPE without silk powder was used as a control for comparison.
  • the filament is clamped with a crimper, cut into a length of 51 mm, and a cotton-like fiber of 10 g each.
  • A is 6.6 d (tex)
  • B is 6.3 d (tex)
  • the questionnaire was for 13 women in their 20s, 2 men, 3 women in their 30s, 2 men, 3 men in their 40s, 2 women in their 50s, and 2 men. I asked her name and asked her to choose between A and B.
  • Hydrophobic polymers such as PE and PP, have no hygroscopic properties, so they are slicked, but the moisture-absorbing silk powder in them gives a slimy feel ⁇ )
  • the silk powder (B) of Example 1 was put into PE together with a plasticizer, and kneaded with a laboplast mill (Toyo Seiki Seisakusho) at 145 ° C for 25 minutes. The yarn was kneaded to make a chip for spinning.
  • a laboplast mill Toyo Seiki Seisakusho
  • the weight ratio of silk powder to PE in this chip is 1.5 to 8.5.
  • the raw silk of silkworm is boiled with a 50% volume of 0.1% aqueous sodium carbonate solution for one hour and scoured to make fibroin fiber (silk thread). Then, 8 g of sodium carbonate was added, and the mixture was boiled at normal pressure for 5 hours, washed with water and dried.
  • the silk material is ground with a stirring and crushing device (Ishikawa type), and then crushed with a rotary impact crusher [Sample Mill KI-1 manufactured by Fuji Electric Industries Co., Ltd.].
  • the mixture was pulverized with a pulverizer (current jet CJ-10 manufactured by Nisshin Flour Milling Co., Ltd.).
  • the particle size of the obtained silk powder is 0! ⁇ 1 2.
  • the average particle size was 5.3 m.
  • the resin as a raw material of the synthetic fiber and the silk powder did not mix well and did not flow smoothly, so that many defective products were produced.
  • the present invention relates to a synthetic fiber produced from a thermoplastic synthetic polymer containing silk powder, and particularly relates to a synthetic fiber excellent in biocompatibility and also excellent in durability and moldability. As long as the principle is not deviated, it can be applied to clothing, medical materials, etc., and similar effects can be expected.

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Textile Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Multicomponent Fibers (AREA)
  • Artificial Filaments (AREA)

Abstract

La présente invention concerne une fibre composite âme-gaine biocompatible, le matériau constitutif de l'âme comprenant un polymère synthétique thermoplastique et le matériau constitutif de la gaine comprenant de la poudre de soie sensiblement dépourvue de particules dont le diamètre est supérieur à 10 νm et un polymère synthétique thermoplastique qui a un point de fusion de 200 °C ou moins. L'invention a également pour objet une fibre biocompatible qui comprend une poudre de soie sensiblement dépourvue de particules dont le diamètre est supérieur à 10 νm et un polymère synthétique thermoplastique qui a un point de fusion de 200 °C ou moins. La fibre contient un polymère synthétique thermoplastique en tant que composante principale et se caractérise par une excellente biocompatibilité, et d'excellents aspect soyeux, confort et propriété de retenue de l'humidité et analogue. Bien que la fibre contienne une quantité considérable de poudre de soie, sa résistance est peu réduite et est satisfaisante au cours de son utilisation pratique.
PCT/JP2003/006438 2002-05-23 2003-05-23 Fibre composite ame-gaine biocompatible, fibre synthetique biocompatible et procede de production WO2003100144A1 (fr)

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AU2003242411A AU2003242411A1 (en) 2002-05-23 2003-05-23 Biocompatible core-shell composite fiber, biocompatible synthetic fiber and method for production thereof

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JP2002148849A JP3855162B2 (ja) 2002-05-23 2002-05-23 生体適合性芯鞘型複合繊維及びその製造方法
JP2002-148849 2002-05-23

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JP4875305B2 (ja) * 2005-02-10 2012-02-15 有限会社プロライフ 改質布帛
CN102071488B (zh) * 2010-12-17 2012-05-30 北京中纺优丝特种纤维科技有限公司 一种皮芯型抗菌有色聚丙烯纤维及其制备方法

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JPH0530169U (ja) * 1991-09-26 1993-04-20 セーレン株式会社 天然セリシン繊維
JPH06322610A (ja) * 1993-05-14 1994-11-22 Toray Ind Inc ポリオレフィン系繊維の製造方法
JPH10212417A (ja) * 1997-01-29 1998-08-11 Ain Kosan Kk 成形素材及びその製造方法、前記成形素材を用いた合成繊維、前記成形素材を用いた合成フィルム、及び前記成形素材を用いた合成繊維紡糸用チップ
JPH1121724A (ja) * 1997-07-01 1999-01-26 Kuraray Co Ltd 改質された複合繊維

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JPH0530169U (ja) * 1991-09-26 1993-04-20 セーレン株式会社 天然セリシン繊維
JPH06322610A (ja) * 1993-05-14 1994-11-22 Toray Ind Inc ポリオレフィン系繊維の製造方法
JPH10212417A (ja) * 1997-01-29 1998-08-11 Ain Kosan Kk 成形素材及びその製造方法、前記成形素材を用いた合成繊維、前記成形素材を用いた合成フィルム、及び前記成形素材を用いた合成繊維紡糸用チップ
JPH1121724A (ja) * 1997-07-01 1999-01-26 Kuraray Co Ltd 改質された複合繊維

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