WO2003085103A3 - Purified polypeptides involved in nucleotide hydrolysis - Google Patents

Purified polypeptides involved in nucleotide hydrolysis Download PDF

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Publication number
WO2003085103A3
WO2003085103A3 PCT/CA2003/000472 CA0300472W WO03085103A3 WO 2003085103 A3 WO2003085103 A3 WO 2003085103A3 CA 0300472 W CA0300472 W CA 0300472W WO 03085103 A3 WO03085103 A3 WO 03085103A3
Authority
WO
WIPO (PCT)
Prior art keywords
purified polypeptides
polypeptides involved
nucleotide hydrolysis
nucleotide
hydrolysis
Prior art date
Application number
PCT/CA2003/000472
Other languages
French (fr)
Other versions
WO2003085103A2 (en
Inventor
Aled Edwards
Akil Dharamsi
Masoud Vedadi
Megan Domagala
Dhushy Kanagarajah
Donald Awrey
Bryan Beattie
Merry-Lynn Mcdonald
Kathleen Nethery
Kamran Mansoury
Hui Ouyang
Original Assignee
Affinium Pharm Inc
Aled Edwards
Akil Dharamsi
Masoud Vedadi
Megan Domagala
Dhushy Kanagarajah
Donald Awrey
Bryan Beattie
Merry-Lynn Mcdonald
Kathleen Nethery
Kamran Mansoury
Hui Ouyang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affinium Pharm Inc, Aled Edwards, Akil Dharamsi, Masoud Vedadi, Megan Domagala, Dhushy Kanagarajah, Donald Awrey, Bryan Beattie, Merry-Lynn Mcdonald, Kathleen Nethery, Kamran Mansoury, Hui Ouyang filed Critical Affinium Pharm Inc
Priority to AU2003213941A priority Critical patent/AU2003213941A1/en
Publication of WO2003085103A2 publication Critical patent/WO2003085103A2/en
Publication of WO2003085103A3 publication Critical patent/WO2003085103A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Abstract

The present invention relates to polypeptide targets for pathogenic bacteria. The invention also provides biochemical and biophysical characteristics of those polypeptides.
PCT/CA2003/000472 2002-04-04 2003-04-04 Purified polypeptides involved in nucleotide hydrolysis WO2003085103A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003213941A AU2003213941A1 (en) 2002-04-04 2003-04-04 Purified polypeptides involved in nucleotide hydrolysis

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US36982202P 2002-04-04 2002-04-04
US60/369,822 2002-04-04
US37086002P 2002-04-08 2002-04-08
US37084902P 2002-04-08 2002-04-08
US37085402P 2002-04-08 2002-04-08
US60/370,854 2002-04-08
US60/370,860 2002-04-08
US60/370,849 2002-04-08
US37106602P 2002-04-09 2002-04-09
US37115102P 2002-04-09 2002-04-09
US60/371,066 2002-04-09
US60/371,151 2002-04-09

Publications (2)

Publication Number Publication Date
WO2003085103A2 WO2003085103A2 (en) 2003-10-16
WO2003085103A3 true WO2003085103A3 (en) 2004-03-25

Family

ID=28795397

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2003/000472 WO2003085103A2 (en) 2002-04-04 2003-04-04 Purified polypeptides involved in nucleotide hydrolysis

Country Status (2)

Country Link
AU (1) AU2003213941A1 (en)
WO (1) WO2003085103A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002083855A2 (en) * 2001-04-16 2002-10-24 Wyeth Holdings Corporation Novel streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002083855A2 (en) * 2001-04-16 2002-10-24 Wyeth Holdings Corporation Novel streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ABOLA E ET AL: "AUTOMATION OF X-RAY CRYSTALLOGRAPHY", NATURE STRUCTURAL BIOLOGY, NEW YORK, NY, US, vol. 7, no. SUPPL, November 2000 (2000-11-01), pages 973 - 977, XP001062873, ISSN: 1072-8368 *
BAGBY S ET AL: "Optimization of protein solubility and stability for protein nuclear magnetic resonance.", METHODS IN ENZYMOLOGY. UNITED STATES 2001, vol. 339, 2001, pages 20 - 41, XP001152932, ISSN: 0076-6879 *
DATABASE EMBL [online] 31 July 2001 (2001-07-31), "Streptococcus pneumoniae TIGR4 section 142 of 194 of the complete genome", XP002252426, Database accession no. AE007459 *
KAY L E: "Nuclear magnetic resonance methods for high molecular weight proteins: a study involving a complex of maltose binding protein and beta-cyclodextrin.", METHODS IN ENZYMOLOGY. UNITED STATES 2001, vol. 339, 2001, pages 174 - 203, XP001152928, ISSN: 0076-6879 *
KRAFT P ET AL: "Infrared, surface-assisted laser desorption ionization mass spectrometry on frozen aqueous solutions of proteins and peptides using suspensions of organic solids", JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, ELSEVIER SCIENCE INC., NEW YORK, NY, US, vol. 9, no. 9, September 1998 (1998-09-01), pages 912 - 924, XP004149186, ISSN: 1044-0305 *
MASSIDDA ET AL: "Unconventional organization of the division and cell wal gene cluster of Streptococcus pneumonia", MICROBIOLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, GB, vol. 144, no. PART 11, November 1998 (1998-11-01), pages 3069 - 3078, XP002110571, ISSN: 1350-0872 *
THOMA R ET AL: "Efficient expression, purification and crystallisation of two hyperthermostable enzymes of histidine biosynthesis", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 454, no. 1-2, 2 July 1999 (1999-07-02), pages 1 - 6, XP004259914, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
AU2003213941A8 (en) 2003-10-20
WO2003085103A2 (en) 2003-10-16
AU2003213941A1 (en) 2003-10-20

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