WO2003069338A3 - Analyse von vitalstoffen - Google Patents

Analyse von vitalstoffen Download PDF

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Publication number
WO2003069338A3
WO2003069338A3 PCT/EP2003/001359 EP0301359W WO03069338A3 WO 2003069338 A3 WO2003069338 A3 WO 2003069338A3 EP 0301359 W EP0301359 W EP 0301359W WO 03069338 A3 WO03069338 A3 WO 03069338A3
Authority
WO
WIPO (PCT)
Prior art keywords
analysis
biological sample
vital substances
sample
proteins
Prior art date
Application number
PCT/EP2003/001359
Other languages
English (en)
French (fr)
Other versions
WO2003069338A2 (de
Inventor
Juergen Wilhelm Rich Bernhardt
Felix Oliver Heinrich
Karin Engelhart-Jentzsch
Original Assignee
Biotesys Gmbh
Juergen Wilhelm Rich Bernhardt
Felix Oliver Heinrich
Karin Engelhart-Jentzsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotesys Gmbh, Juergen Wilhelm Rich Bernhardt, Felix Oliver Heinrich, Karin Engelhart-Jentzsch filed Critical Biotesys Gmbh
Priority to JP2003568408A priority Critical patent/JP2005517926A/ja
Priority to EP03704594A priority patent/EP1474685A2/de
Priority to US10/504,185 priority patent/US20050118671A1/en
Priority to AU2003206882A priority patent/AU2003206882A1/en
Publication of WO2003069338A2 publication Critical patent/WO2003069338A2/de
Publication of WO2003069338A3 publication Critical patent/WO2003069338A3/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zur Bestimmung des Versorgungsprofils zumindest eines Mikronutrienten in einer biologischen Probe. Aus der biologischen Probe, insbesondere nach der Bestimmung der Anzahl und/oder Menge der darin enthaltenen Zellen, werden durch Lyse der Zellen, gegebenenfalls nach deren Isolation, Zellproteine, insbesondere Zellmembranproteine, freigesetzt und dadurch, erforderlichenfalls nach einer Denaturierung. Mikronutrienten aus dem Lysat gewonnen und deren Anteil an der Probe, insbesondere deren Gewicht, als Mass für die intrazelluläre Konzentration gemessen.
PCT/EP2003/001359 2002-02-12 2003-02-12 Analyse von vitalstoffen WO2003069338A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2003568408A JP2005517926A (ja) 2002-02-12 2003-02-12 生体物質の分析
EP03704594A EP1474685A2 (de) 2002-02-12 2003-02-12 Analyse von vitalstoffen
US10/504,185 US20050118671A1 (en) 2002-02-12 2003-02-12 Analysis of vital substances
AU2003206882A AU2003206882A1 (en) 2002-02-12 2003-02-12 Analysis of vital substances

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA219/02 2002-02-12
AT2192002 2002-02-12

Publications (2)

Publication Number Publication Date
WO2003069338A2 WO2003069338A2 (de) 2003-08-21
WO2003069338A3 true WO2003069338A3 (de) 2004-03-25

Family

ID=27671428

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/001359 WO2003069338A2 (de) 2002-02-12 2003-02-12 Analyse von vitalstoffen

Country Status (5)

Country Link
US (1) US20050118671A1 (de)
EP (1) EP1474685A2 (de)
JP (1) JP2005517926A (de)
AU (1) AU2003206882A1 (de)
WO (1) WO2003069338A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102662026B (zh) * 2012-05-30 2014-04-30 山东阿如拉药物研究开发有限公司 一种中药前列宁制剂的检测方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7700365B2 (en) 2004-10-29 2010-04-20 Mayo Foundation For Medical Education And Research Vitamin D deficiencies
WO2006066804A1 (de) * 2004-12-20 2006-06-29 Biotesys Gmbh In-vitro diagnostikum für analyten mit immunspezifischem nachweis
AT10300U1 (de) 2008-02-27 2008-12-15 Biotesys Gmbh Kit zur gewinnung und aufbereitung zellulärer proben
US20110212534A1 (en) * 2008-08-11 2011-09-01 Taylor Robert L Methods for determining levels of 1,25 dihydroxy vitamin d2 and d3
CN102435700B (zh) * 2011-09-22 2014-07-30 明一(福建)婴幼儿营养品有限公司 测定婴幼儿食品和乳品中维生素ade的含量的方法
CN103399117B (zh) * 2013-08-26 2015-09-30 中国水产科学研究院黄海水产研究所 水产品中硒形态的检测方法
CN103439444A (zh) * 2013-09-10 2013-12-11 广西大学 检测鱼类血浆中肉碱含量的高效液相色谱法
CN105259284A (zh) * 2015-09-25 2016-01-20 中国科学技术大学苏州研究院 一种富硒螺旋藻中硒形态测定的方法
CN107515270B (zh) * 2017-08-24 2021-01-08 广西壮族自治区食品药品检验所 灵芝二维甲硫氨酸胶囊的质量控制方法
JP6925933B2 (ja) 2017-10-25 2021-08-25 アークレイ株式会社 アスコルビン酸測定用電極およびバイオセンサ
CN111595970B (zh) * 2017-11-20 2022-10-21 国药控股星鲨制药(厦门)有限公司 高效液相色谱检测复方三维右旋泛酸钙糖浆维生素的方法
CN108088925A (zh) * 2017-12-14 2018-05-29 金华傲农生物科技有限公司 一种浓缩饲料脂溶性维生素含量的检测方法
CN108776190B (zh) * 2018-04-19 2020-08-07 中国林业科学研究院林业研究所 沙棘中酚类物质定量检测方法
CN110763788A (zh) * 2018-07-26 2020-02-07 深圳华大生命科学研究院 一种定量检测血浆中5种脂溶性维生素的试剂盒及方法
CN109541110A (zh) * 2018-12-07 2019-03-29 浙江核力欣健药业有限公司 一种检测小儿碳酸钙d3颗粒中维生素d3有关物质的方法
CN110308229A (zh) * 2019-08-13 2019-10-08 深圳凯吉星农产品检测认证有限公司 一种测定海藻类制品中无机砷含量的方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4304728A1 (de) * 1993-02-13 1994-08-18 Igor Dr Popov Verfahren und Testbesteck zur Bestimmung von Ascorbinsäure in biologischen Proben
EP0840127A1 (de) * 1996-10-30 1998-05-06 Nikken Foods Company Limited Tabelle und Verfahren zur Beurteilung von Vitamin-Mineral Profildaten
WO2000010579A1 (en) * 1998-08-18 2000-03-02 California Skin Research Institute Method for detection of biological factors in epidermis
US6287796B1 (en) * 1998-06-16 2001-09-11 Niadyne Inc Biochemical method to measure niacin status in a biological sample

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818516A (en) * 1985-04-22 1989-04-04 The Board Of Regents For The University Of Oklahoma Method of nutritional assessment and therapy
US5051249A (en) * 1990-01-11 1991-09-24 Jack Metcoff Method of nutritional therapy
WO1995012666A1 (en) * 1993-11-02 1995-05-11 Innogenetics N.V. Human foam cells and methods for preparing them, monoclonal antibodies to said foam cells and their pharmaceutical and diagnostic use
US5800979A (en) * 1994-12-01 1998-09-01 Kolhouse; J. Fred Gas chromatography/mass spectrometric determination of folic acid coenzymes
US6365407B1 (en) * 2001-03-05 2002-04-02 Council Of Scientific & Industrial Research Culture medium composition useful for induction and proliferation of Taxus calli

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4304728A1 (de) * 1993-02-13 1994-08-18 Igor Dr Popov Verfahren und Testbesteck zur Bestimmung von Ascorbinsäure in biologischen Proben
EP0840127A1 (de) * 1996-10-30 1998-05-06 Nikken Foods Company Limited Tabelle und Verfahren zur Beurteilung von Vitamin-Mineral Profildaten
US6287796B1 (en) * 1998-06-16 2001-09-11 Niadyne Inc Biochemical method to measure niacin status in a biological sample
WO2000010579A1 (en) * 1998-08-18 2000-03-02 California Skin Research Institute Method for detection of biological factors in epidermis

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ANNOUS KATHLEEN F ET AL: "Pantothenic acid uptake and metabolism by red blood cells of rats", JOURNAL OF NUTRITION, vol. 125, no. 10, 1995, pages 2586 - 2593, XP009019061, ISSN: 0022-3166 *
LENTON KEVIN J ET AL: "Direct correlation of glutathione and ascorbate and their dependence on age and season in human lymphocytes", AMERICAN JOURNAL OF CLINICAL NUTRITION, vol. 71, no. 5, May 2000 (2000-05-01), pages 1194 - 1200, XP002257892, ISSN: 0002-9165 *
PIYATHILAKE C J ET AL: "Cigarette smoking, intracellular vitamin deficiency, and occurrence of micronuclei in epithelial cells of the buccal mucosa", CANCER EPIDEMIOLOGY BIOMARKERS AND PREVENTION, vol. 4, no. 7, 1995, pages 751 - 758, XP009019081, ISSN: 1055-9965 *
PIYATHILAKE C J ET AL: "Effect of smoking on buccal mucosal vitamin B-12 levels", FASEB JOURNAL, vol. 7, no. 3-4, 1993, Meeting of the Federation of American Societies for Experimental Biology on Experimental Biology '93;New Orleans, Louisiana, USA; March 28-April 1, 1993, pages A743, XP009019165, ISSN: 0892-6638 *
PIYATHILAKE C J ET AL: "Effect of smoking on folate levels in buccal mucosal cells", INTERNATIONAL JOURNAL OF CANCER, vol. 52, no. 4, 1992, pages 566 - 569, XP009019156, ISSN: 0020-7136 *
VANDERVEEN E ET AL: "VITAMINS AND OTHER NUTRIENTS", REMINGTON'S PHARMACEUTICAL SCIENCES, EASTON, MACK PUBLISHING CO, US, 1985, pages 1002 - 1005, XP002054039 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102662026B (zh) * 2012-05-30 2014-04-30 山东阿如拉药物研究开发有限公司 一种中药前列宁制剂的检测方法

Also Published As

Publication number Publication date
AU2003206882A1 (en) 2003-09-04
US20050118671A1 (en) 2005-06-02
EP1474685A2 (de) 2004-11-10
WO2003069338A2 (de) 2003-08-21
JP2005517926A (ja) 2005-06-16

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