WO2003018045A1 - A pharmaceutical being used for treating hiv infection, the composition and uses thereof - Google Patents

A pharmaceutical being used for treating hiv infection, the composition and uses thereof Download PDF

Info

Publication number
WO2003018045A1
WO2003018045A1 PCT/CN2002/000405 CN0200405W WO03018045A1 WO 2003018045 A1 WO2003018045 A1 WO 2003018045A1 CN 0200405 W CN0200405 W CN 0200405W WO 03018045 A1 WO03018045 A1 WO 03018045A1
Authority
WO
WIPO (PCT)
Prior art keywords
group
pharmaceutical
hiv infection
treating hiv
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2002/000405
Other languages
English (en)
French (fr)
Inventor
Genfa Zhou
Wangni Tian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tianjin Fusogen Biotech Co Ltd
Original Assignee
Tianjin Fusogen Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tianjin Fusogen Biotech Co Ltd filed Critical Tianjin Fusogen Biotech Co Ltd
Priority to DK02742656T priority Critical patent/DK1421946T3/da
Priority to US10/487,724 priority patent/US6962900B2/en
Priority to DE60228269T priority patent/DE60228269D1/de
Priority to JP2003522562A priority patent/JP2004538334A/ja
Priority to EP02742656A priority patent/EP1421946B1/en
Priority to HK04109370.7A priority patent/HK1067531B/zh
Publication of WO2003018045A1 publication Critical patent/WO2003018045A1/zh
Anticipated expiration legal-status Critical
Priority to US11/265,892 priority patent/US7335727B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PCT/CN2002/000405 2001-08-29 2002-06-06 A pharmaceutical being used for treating hiv infection, the composition and uses thereof Ceased WO2003018045A1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DK02742656T DK1421946T3 (da) 2001-08-29 2002-06-06 Et farmaceutisk præparat til behandling af HIV-infektion
US10/487,724 US6962900B2 (en) 2001-08-29 2002-06-06 Pharmaceutical being used for treating HIV infection, the composition and uses thereof
DE60228269T DE60228269D1 (de) 2001-08-29 2002-06-06 Pharmazeutische zusammensetzung zur behandlung einer hiv-infektion
JP2003522562A JP2004538334A (ja) 2001-08-29 2002-06-06 Ｈｉｖ感染の治療に使用される薬剤とその成分と使用法
EP02742656A EP1421946B1 (en) 2001-08-29 2002-06-06 A pharmaceutical composition for treating hiv infection
HK04109370.7A HK1067531B (zh) 2001-08-29 2002-06-06 用於治疗hiv感染的药物
US11/265,892 US7335727B2 (en) 2001-08-29 2005-11-03 Pharmaceutical used for treating HIV infection, the composition and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN01130985A CN1100564C (zh) 2001-08-29 2001-08-29 用于治疗hiv感染的药物、其组合物及其用途
CN01130985.7 2001-08-29

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10487724 A-371-Of-International 2002-06-06
US11/265,892 Continuation US7335727B2 (en) 2001-08-29 2005-11-03 Pharmaceutical used for treating HIV infection, the composition and uses thereof

Publications (1)

Publication Number Publication Date
WO2003018045A1 true WO2003018045A1 (en) 2003-03-06

Family

ID=4670295

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2002/000405 Ceased WO2003018045A1 (en) 2001-08-29 2002-06-06 A pharmaceutical being used for treating hiv infection, the composition and uses thereof

Country Status (9)

Country Link
US (2) US6962900B2 (zh)
EP (1) EP1421946B1 (zh)
JP (1) JP2004538334A (zh)
CN (1) CN1100564C (zh)
AT (1) ATE404215T1 (zh)
DE (1) DE60228269D1 (zh)
DK (1) DK1421946T3 (zh)
RU (1) RU2290197C2 (zh)
WO (1) WO2003018045A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8603965B2 (en) 2006-06-12 2013-12-10 Fusogen Pharmaceuticals, Inc. Pharmaceutical composition for the prophylaxis and treatment of HIV infection and its use

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1100564C (zh) * 2001-08-29 2003-02-05 周根发 用于治疗hiv感染的药物、其组合物及其用途
JP2007517522A (ja) * 2004-01-07 2007-07-05 トリメリス，インコーポレーテッド ＨＩＶｇｐ４１ＨＲ２由来の合成ペプチド、およびヒト免疫不全ウイルスの伝播を阻止する治療におけるその使用
EP1989220B1 (en) 2006-02-02 2011-12-14 Trimeris, Inc. Hiv fusion inhibitor peptides with improved biological properties
US7662547B2 (en) * 2006-05-05 2010-02-16 George Mason Intellectual Properties, Inc. Compositions and methods for detecting and treating HIV infections
BRPI0809995A2 (pt) * 2007-04-03 2015-07-21 Trimeris Inc Composição, e, métodos para a liberação prolongada de um peptídeo em um paciente e para melhorar um sintoma associado com uma infecção por hiv
BRPI0817697A2 (pt) * 2007-09-25 2015-04-07 Trimeris Inc Método de síntese de um peptídeo, conjunto de fragmentos de peptídeo, e, peptídeo
US20100021427A1 (en) * 2008-05-29 2010-01-28 Tianjin Fusogen Pharmaceuticals, Inc. Use of Antiviral Peptides For Treatment of Infections Caused by Drug-Resistant HIV
EP2603241A2 (en) 2010-08-11 2013-06-19 Jv Bio Srl Multimeric inhibitors of viral fusion and uses thereof
CN102180951B (zh) * 2011-05-03 2012-09-26 中国医学科学院病原生物学研究所 胆固醇修饰的抗hiv多肽药物及其用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994002505A1 (en) * 1992-07-20 1994-02-03 Duke University Compounds which inhibit hiv replication
WO1999062945A2 (en) * 1998-06-05 1999-12-09 Peptide Solutions, Inc. Peptide antigens for detection of hiv, hcv and other microbial infections
WO2000006599A1 (en) * 1998-07-30 2000-02-10 Whitehead Institute For Biomedical Research Inhibitors of hiv membrane fusion

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992004374A1 (fr) * 1990-09-11 1992-03-19 Seikagaku Kogyo Co., Ltd. Nouveau polypeptide et medicament anti-vih prepare a partir de ce polypeptide
HUT61036A (en) * 1991-05-02 1992-11-30 Seikagaku Kogyo Co Ltd Process for producing new polypeptides capable of linking to lipopolysaccharides and pharmaceutical compositions comprising same as active ingredients
US5424063A (en) * 1992-01-09 1995-06-13 The Dow Chemical Company Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process
DE69426725T2 (de) * 1993-09-11 2001-09-06 Polimun Scientific Immunbiologische Forschungsgesellschaft Mbh, Wien Peptide, die neutralisierende antikörper gegen genetisch divergierende hiv-1 stämme, induzieren
IL110929A0 (en) * 1993-09-13 1994-11-28 Armel Sa Multiple branch peptide constructions and pharmaceutical compositions containing them
CZ287239B6 (en) * 1993-10-14 2000-10-11 Seikagaku Kogyo Co Ltd Polypeptides exhibiting antimicrobial and antiviral activity and pharmaceutical preparations containing thereof
RU2137768C1 (ru) * 1993-12-15 1999-09-20 Мерк энд Ко, Инк. Ингибиторы hiv протеазы
US6258782B1 (en) * 1998-05-20 2001-07-10 Trimeris, Inc. Hybrid polypeptides with enhanced pharmacokinetic properties
CN1100564C (zh) * 2001-08-29 2003-02-05 周根发 用于治疗hiv感染的药物、其组合物及其用途

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994002505A1 (en) * 1992-07-20 1994-02-03 Duke University Compounds which inhibit hiv replication
WO1999062945A2 (en) * 1998-06-05 1999-12-09 Peptide Solutions, Inc. Peptide antigens for detection of hiv, hcv and other microbial infections
WO2000006599A1 (en) * 1998-07-30 2000-02-10 Whitehead Institute For Biomedical Research Inhibitors of hiv membrane fusion

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8603965B2 (en) 2006-06-12 2013-12-10 Fusogen Pharmaceuticals, Inc. Pharmaceutical composition for the prophylaxis and treatment of HIV infection and its use

Also Published As

Publication number Publication date
US20060100139A1 (en) 2006-05-11
HK1067531A1 (zh) 2005-04-15
US6962900B2 (en) 2005-11-08
US7335727B2 (en) 2008-02-26
US20040248789A1 (en) 2004-12-09
EP1421946B1 (en) 2008-08-13
CN1334122A (zh) 2002-02-06
RU2004108858A (ru) 2005-05-10
EP1421946A1 (en) 2004-05-26
ATE404215T1 (de) 2008-08-15
EP1421946A4 (en) 2005-08-31
CN1100564C (zh) 2003-02-05
DK1421946T3 (da) 2008-12-01
RU2290197C2 (ru) 2006-12-27
JP2004538334A (ja) 2004-12-24
DE60228269D1 (de) 2008-09-25

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