WO2002098548A1 - Dispositif de melange rotatif de type mouvement a trois dimensions - Google Patents

Dispositif de melange rotatif de type mouvement a trois dimensions Download PDF

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Publication number
WO2002098548A1
WO2002098548A1 PCT/CN2002/000357 CN0200357W WO02098548A1 WO 2002098548 A1 WO2002098548 A1 WO 2002098548A1 CN 0200357 W CN0200357 W CN 0200357W WO 02098548 A1 WO02098548 A1 WO 02098548A1
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WIPO (PCT)
Prior art keywords
dimensional
mixing device
sleeve
rotary mixing
tray
Prior art date
Application number
PCT/CN2002/000357
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English (en)
French (fr)
Inventor
Rongda Yi
Original Assignee
Rongda Yi
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Publication date
Application filed by Rongda Yi filed Critical Rongda Yi
Priority to US10/479,054 priority Critical patent/US7059762B2/en
Publication of WO2002098548A1 publication Critical patent/WO2002098548A1/zh

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes

Definitions

  • the invention relates to a liquid oscillating mixing device, in particular to a three-dimensional kinematic rotary mixing device suitable for mixing or cultivating various microorganisms and chemical solutions for chemical, biochemical, and microbiological experiments. Background technique
  • the purpose of the present invention is to overcome the shortcomings of the existing oscillating mixing device, and to provide a three-dimensional motion-type rotary mixing device that can make the liquid in the container three-dimensionally move, so that the liquid in the bottle can automatically generate a vortex, and obtain sufficient mixing.
  • the present invention provides a three-dimensional motion type rotary mixing device, which is characterized in that it includes a driving mechanism capable of generating three-dimensional motion and a container fixing mechanism connected to the driving mechanism, and the driving mechanism and the container fixing mechanism There is a connection between
  • the driving mechanism is equipped with a motor and a transmission shaft on a base, and a central shaft is installed in the transmission shaft.
  • the upper and lower ends of the transmission shaft are respectively equipped with passive wheels connected to the motor and a bevel sleeve for generating three-dimensional movement.
  • the lower end face of the bevel sleeve is a flat surface, and the upper end face is an inclined surface.
  • the lower end surface of the bevel sleeve is a plane, and the upper end surface is a curved surface.
  • the curved surface has a highest point and a highest point.
  • the bearing assembly includes a bearing sleeve, a universal bearing housing, and a universal bearing, wherein the bearing sleeve is connected to the inclined sleeve, the universal bearing housing is installed in the bearing housing, and the universal bearing is installed in the universal bearing housing.
  • the container fixing mechanism is composed of a tray and a fixing base, wherein the tray is respectively connected with a driving mechanism and a flexible connecting member; the fixing base is composed of at least two fixing pieces and a strong magnet block connected with the fixing piece, and they can be arranged on the tray On any part of it to fix the valleys of different sizes.
  • the fixing piece is angled or curved and is bent inward.
  • a strong magnet block is fixed on the bottom of the fixing piece and is attracted to the tray by magnetic force, and its position can be adjusted arbitrarily.
  • the flexible connector is a rubber bellows.
  • the contribution of the present invention is that it effectively overcomes the limitations of the existing oscillating mixing device, and realizes the three-dimensional movement of the liquid in the container on the tray through a very simple structure, so that the liquid in the container can not only rotate but also rotate. Simultaneously make up and down oscillating motion, so that the liquid can be fully oscillated and mixed.
  • the present invention is provided with a strong magnet fixing device on the tray, and the position of the device can be arbitrarily adjusted, so it is not only flexible to use and convenient to operate, but also suitable for fixing triangle bottles and other containers of different sizes. Very wide. The above characteristics make the invention have the following wide applications in the fields of chemistry, biochemistry, microorganisms, etc .: 1.
  • a magnetic stirrer for dosing and dialysis without the need for a magnetic rod; 2. When adjusted to a low speed, it can be used for various Staining, decoloring, and cell culture; 3.
  • a cabinet and a temperature control device are installed to become a general temperature-controlled shaker (flask) for the cultivation of microorganisms; 4.
  • a height-adjustable partition is provided, which can be used as a temperature-controlled incubator to store different sizes of cultures.
  • the invention also has the characteristics of compact structure, low cost, and being capable of realizing various functions. Overview of the drawings
  • Fig. 1 is a schematic exploded view of the present invention.
  • FIG. 2 is a schematic structural diagram of a transmission shaft according to the present invention.
  • Fig. 3 is a schematic diagram of the overall structure of the present invention. Nie Jia implementation
  • the three-dimensional motion type rotary mixing device of the present invention includes a driving mechanism 10 and a container fixing mechanism 20, and a flexible connecting member 30 is connected between the driving mechanism and the container fixing mechanism.
  • the specific structure of the above mechanism is given in FIG. 1.
  • the driving mechanism 10 includes a motor 11, a transmission shaft 12, a central shaft 13, a driven wheel 14, a beveled sleeve 15 and a universal bearing assembly 16, where the motor 11 is The adjusting motor is fixed on the base 40 through a bracket, and a driving wheel is installed at the output end of the motor.
  • a transmission shaft 12 is installed in the center of the base, and its structure is shown in FIG. 2.
  • the transmission shaft is a hollow shaft.
  • the shaft is equipped with a central shaft 13.
  • the shaft is a non-rotating support shaft.
  • the lower end of the shaft passes through a positioning sleeve 17 and a radial bearing. 181 is connected to the base, and its top end is connected to the universal bearing assembly 16.
  • the lower end of the transmission shaft is provided with a driven wheel 14 through a radial bearing 182.
  • the driving wheel and the driven wheel may be gears or belt pulleys. In this example, the belt pulley is used by the motor to drive the transmission shaft to rotate.
  • the upper end of the transmission shaft is provided with a bevel sleeve 15, which is an important component for generating three-dimensional movement in the present invention.
  • the lower end is a plane, the upper end is a bevel, and the cross section is wedge-shaped.
  • the upper end of the bevel sleeve is also It can be a surface with a highest point and a lowest point.
  • the upper part of the bevel sleeve is provided with a universal bearing assembly 16 which includes a bearing sleeve 161, a universal bearing housing 162 and a universal bearing 163, wherein the bearing sleeve is connected to the bevel sleeve, and the connection structure is on the lower end face and the bevel of the bearing sleeve
  • the upper end surface of the sleeve is respectively provided with three connecting posts (not shown in the figure) and three corresponding connecting holes 151, so that the two are plugged in.
  • a radial bearing 183 is installed in the bearing sleeve 161, and a universal shaft seat 162 is installed in the radial bearing.
  • the universal bearing is installed in the universal bearing seat.
  • the upper end of the bearing assembly is connected to the container fixing mechanism 20.
  • the container fixing mechanism 20 is composed of a tray 21 and a fixing seat 22.
  • the tray is square and made of metal. It can make three-dimensional movement under the action of the driving mechanism.
  • the tray is provided with a fixing base 22 for fixing a triangular bottle or other container. This fixing base is also an important component of the present invention. The main point is that its position on the tray can be adjusted arbitrarily.
  • the fixing base is composed of at least two fixing pieces 221 and It is composed of a strong magnet block 222, in which the fixing piece is angular or solitary and bends inward.
  • the strong magnet piece is angular and is made of a strong permanent magnet material such as neodymium iron boron. It is welded and fixed to the bottom of the fixing piece.
  • a stainless steel jacket is mounted on the strong magnet block to make it more beautiful.
  • a flexible protective layer can be affixed on the contact surface between the holder and the container to protect the glass container.
  • the fixing base 22 is attracted to the tray by the magnetic force of the strong magnet block, so that the position on the tray can be arbitrarily adjusted. They can be set on any part of the tray to clamp the holder.
  • a flexible connector 30 is connected to the bottom of the container fixing mechanism.
  • the flexible connector is a rubber bellows. The upper end of the bellows is connected to the tray 21 through the upper flange 31 and the lower end is connected through The lower flange 32 is connected to the casing 50 covered on the base 40, and the transmission shaft 12 passes through the bellows.
  • FIG. 3 shows an application example of the present invention.
  • a three-dimensional kinematic rotary mixing device according to the present invention is provided with a casing 60, and the casing is provided with a partition 61 for placing a container such as a triangular flask and a cell culture bottle. Its height can be adjusted by the height-adjusting ladder frames 62 installed on both sides in the cabinet.
  • a control panel 41 is mounted on the front side of the base 40.
  • the speed-adjusting motor 11 drives the transmission shaft 12 to rotate through the driving wheel and the pulley 14, and the bevel sleeve 15 and the universal bearing assembly 16 mounted on the transmission shaft also rotate. Because the upper end surface of the bevel sleeve 15 is an inclined surface, the bearing sleeve 161 also generates a corresponding inclination, forming a lowest and highest position on the upper end surface. They are in different positions on the circumference with the rotation of the drive shaft.
  • the upper part of the universal bearing seat 162 is connected to the casing 50 through a rubber bellows 30, and due to the operation of the bearing sleeve and the angle change of the universal bearing 163, each position on the tray can be moved up and down, At the same time, this up-and-down motion can be transmitted to the next position along the circular trajectory to generate horizontal motion, so that the liquid in the container generates both horizontal rotation and up-and-down vibration.
  • the oscillating compound three-dimensional movement forms a strong stirring effect, so that the liquid in the triangular bottle or container placed on the tray can automatically form a vortex to achieve the purpose of sufficient oscillating mixing.
  • its gas-liquid contact surface is larger than the traditional reciprocating type and two-dimensional motion type, and the amount of dissolved oxygen is greater, which is particularly beneficial to the growth of microbial liquid culture medium.
  • the present invention is not limited to the above embodiments. Any technical solution that generates a three-dimensional motion through a driving mechanism and a container fixing mechanism, and equivalent transformations and deformations related thereto, will fall into the protection scope of the present invention.

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Description

三 维 运 动 式 旋 混 装 置 技术领域
本发明涉及一种液体振荡混合装置 , 特别涉及一种适用于化学、 生化、微生物实验的各种微生物及化学溶液的混合或培养的三维运动 式旋混装置。 背景技术
在化学、生化及微生物实验中， 常需将化学溶液或微生物放入大 小不等的三角瓶、 烧杯、 平亚等各类容器中， 进行振荡混合或培养。 目前国内外市场上用于振荡混合的装置（称为摇瓶机、摇床或振荡器） 虽形式各异， 但运转方式基本可分为两种类型， 一种是往复式， 另一 种是旋转式。其中往复式是通过往复直线运动产生振荡混合； 旋转式 则是通过普通平面绕轴旋转运动产生振荡混合。由于上述两种摇瓶机 及其它类型的摇瓶机所产生振荡运动均只为一维和二维运动，因而其 缺陷也是显而易见的，单纯的往复直线运动只能使容器托盘产生规则 运动，难以使瓶内喲液体形成涡流或类似搅拌的效应， 因而导致液体 混合不均匀， 合效果差。二维运动只能使同一层面的液体得以混合， 而不同层面的液体则得不到充分混合， 如水层和油层。此外， 现有的 振荡混合装置的容器固定装置均不可调节或调节性差，因而每种振荡 混合装置只能适用一定大小的容器，不同大小的容器需要不同类型的 摇瓶机， 因而应用范围有限。 发明内容
本发明的目的在于克服现有振荡混合装置的缺陷，而提供一种能 使容器中液体作三维运动， 因而使瓶内的液体可自动产生涡流， 并得 到充分混合的三维运动式旋混装置。
为实现上述目的，本发明提供一种三维运动式旋混装置， 该装置 特征在于，它包括一个可产生三维运动的驱动机构和一个与上述驱动 机构相连的容器固定机构 ,驱动机构与容器固定机构之间连接有一个
确认本 柔性连接件。 ，
所述驱动机构是在底座上装有电机及传动轴，传动轴内装有中心 轴，传动轴的上下两端分别装有与电机连接的被动轮和用于产生三维 运动的斜面套，斜面套上部装有万向轴承組件，轴承组件上端与容器 固定机构连拉。
所述斜面套的下端面为平面， 上端面为斜面。
所述斜面套的下端面为平面， 上端面为曲面，该曲面有一最高点 和最氐点。
所述轴承组件包括轴承套、万向轴承座及万向轴承， 其中轴承套 与斜面套连接， 万向轴承座装在轴承套内， 万向轴承则装在万向轴承 座内。
所述容器固定机构是由托盘和固定座构成，其中托盘分別与驱动 机构及柔性连接件连接； 固定座由至少两个固定片和与之连成一体的 强磁铁块构成， 它们可设置于托盘上的任意部位， 以卡固不同大小的 谷 。
所述固定片为角形或弧面形并向内弯曲，强磁铁块固定于固定片 底部， 并通过磁力吸附于托盘上， 其位置可任意调整。
所述柔性连接件为橡胶波纹管。
本发明的贡献在于，它有效地克服了现有振荡混合装置的种种局 限性， 通过十分简单的结构实现了托盘上容器内液体的三维运动，使 容器内液体不仅作旋转运动， 而且能在旋转同时作上下的振荡运动， 因而可使液体得到充分的振荡与混合。 同时， 本发明由于在托盘上设 置了强磁铁固定装置，且该装置的位置可以任意调整， 因而不仅使用 灵活，操作方便，而且可适用于大小不同的三角瓶及其它容器的固定， 因此适用范围很广。 上述特点使得本发明在化学、 生化、 微生物等领 域中具有如下广泛的应用： 1、 可用作磁力搅拌器用于配液、 透析而 不需要磁力棒； 2、 调节到低速时， 可用于各种染色、 脱色和细胞培 养； 3、 在本发明的装置上 ^以机箱， 并装设温控装置， 就成为普通 温控摇床（摇瓶机）， 用于微生物的培养； 4、 在机箱内设置可以调节 高度的隔板， 可用作温控培养箱来存放不同大小的培养物。 本发明还具有结构紧凑， 成本低廉且能实现多种功能等特点。 附图概述
下面结合附图及一个优选实施例对本发明作更详细的描述。 图 1是本发明的部件分解示意图。
图 2是本发明的传动轴结构示意图。
图 3是本发明的整体结构示意图。 聂佳实施方式
本发明的三维运动式旋混装置包括驱动机构 10和容器固定机构 20, 驱动机构与容器固定机构之间连接有一个柔性连接件 30。 上述 机构的具体结构由图 1给出，如图示，所述驱动机构 10包括电机 11、 传动轴 12、 中心轴 13、 被动轮 14、 斜面套 15及万向轴承组件 16, 其中电机 11为调整电机， 它通过支架固定于底座 40上， 电机输出端 装有主动轮。 在底座中央装有传动同 12 , 其结构如图 2所示， 该传 动轴为空心轴， 轴内装有中心轴 13 , 该轴为不转动的支撑轴， 其下 端通过定位套 17及向心轴承 181与底座连接， 其顶端则与万向轴承 组件 16相连。 传动轴的下端通过向心轴承 182装有被动轮 14 , 主动 轮与被动轮可以是齿轮， 也可能是皮带轮， 本例中为皮带轮， 电机通 过该皮带轮组带动传动轴转动。 传动轴上端装有斜面套 15 , 该斜面 套是本发明中用于产生三维运动的重要构件， 其下端面为平面， 上端 在为斜面， 横截面呈楔形， 艮显然， 斜面套的上端面也可以是曲面， 该曲面有一最高点和最低点。 斜面套上部装有万向轴承组件 16， 该 轴承组件包括轴承套 161、 万向轴承座 162及万向轴承 163, 其中轴 承套与斜面套连接 ,其连接结构是在轴承套的下端面及斜面套的上端 面分别设有三个连接柱（图中未示出）和与之对应的三个连接孔 151 , 使两者相插接。 轴承套 161内装有向心轴承 183， 向心轴承内装有万 向轴 座 162 , 万向轴承则装在万向轴承座内。 轴承组件上端与容器 固定机构 20连接。所述容器固定机构 20是由托盘 21和固定座 22构 成，其中托盘呈方形，由金属制成，它用螺栓与万向轴承座 162连接， 它可在驱动机构作用下作三维运动。在托盘上装有固定三角瓶或其它 容器用的固定座 22, 该固定座也是本发明的重要构件， 其要点是其 在托盘上的位置可任意调整， 固定座由至少两个固定片 221和与之连 成一体的强磁铁块 222 构成， 其中固定片为角形或孤面形并向内弯 曲， 强磁铁块为角形， 由钕铁硼等强永磁材料制成， 它焊接固定于固 定片底部， 在强磁铁块外装有一个不锈钢外套， 以使其更加美观。 在 固定座与容器的接触面上可贴一层柔性保护层， 以保护玻璃容器。 固 定座 22通过强磁铁块的磁力吸附于托盘上， 使得在托盘上的位置可 任意调整。 它们可设置于托盘上的任意部位来卡固定器， 固定三角瓶 或容器时， 将其放在固定片中间，移协固定片使其夹持住三角瓶或容 器， 而固定座底部的强磁铁块则牢固地吸附于金属托盘上。上述固定 方式使得该旋混装置可适用于各种规格的三角瓶（50ml— 5000ml )或 容器， 不仅操作十分方便， 且连接牢固可靠。 为适应液体的三维运动 方式， 本发明在容器固定机构底部连接有一柔性连接件 30, 该柔性 连接件为橡胶波紋管，该波纹管的上端通过上法兰盘 31与托盘 21连 接， 其下端通过下法兰盘 32与罩在底座 40上的机壳 50连接， 传动 轴 12 自波紋管中穿过。
图 3示出了本发明的应用实例， 如图示，在本发明的三维运动式 旋混装置外装有机箱 60, 机箱内装有一个用于放置三角瓶及细胞培 养瓶等容器的隔板 61 , 其高度可通过装在机壳内两侧的高度调节梯 架 62调节。 底座 40前侧装有控制面板 41。
本发明的工作原理可参照图 1来说明， 调速电机 11经主动轮、 皮带轮 14带动传动轴 12转动， 装在传动轴上的斜面套 15及万向轴 承组件 16也随之转动。 由于斜面套 15的上端面为斜面，使得轴承套 161也产生相应的斜度， 在其上端面形成一最低和最高位置， 它们随 传动轴的转动而处于圆周上的不同位置， 由于托盘 21 固定于万向轴 承座 162上部， 并通过橡胶波紋管 30将其与机壳 50连接， 且由于轴 承套的运转和万向轴承 163的角度变化，使得托盘上的每一个位点可 作上下运动 ,同时又可将这种上下运动沿圆周轨迹传递给下一个位点 产生水平运动， 因而使得容器中液体产生一种既水平旋转， 又上下振 荡的复合三维运动， 这种三维运动形成了强烈的搅拌效应，使得放在 托盘上的三角瓶或容器中的液体可以自动形成涡流而达到充分振荡 混合的目的。且其气液接触面比传统的往复式和二维运动式大，溶氧 量更多， 尤其有利于微生物液体培养基中的生长。
本发明并不局限于上述实施方式 ， 任何通过驱动机构产生并通 过容器固定机构进行三维运动的技术方案及与这相关的等效变换和 变形都将落入本发明的保护范围内。

Claims

杈 要 求 书
1、 一种三维运动式旋混装置， 其特征在于， 它包括一个可产生三维运 动的驱动机构和一个与上述驱动机构相连而作三维运动的容器固定机构， 驱动机构与容器固定机构之间连接有一个柔性连接件。
2、根据权利要求 1所述的三维运动式旋混装置， 其特征在于， 所述驱 动机构是在底座上装有电机及传动轴， 传动轴内装有中心轴， 传动轴的上 下两端分别装有与电机连接的被动轮和用于产生三维运动的斜面套， 斜面 套上部装有万向轴承组件， 轴承组件上端与容器固定机构连接。
3、根据权利要求 2所述的三维运动式旋混装置， 其特征在于， 所述斜 面套的下端面为平面， 上端面为斜面。
4、根据权利要求 2。所述的三维运动式旋混装置， 其特征在于， 所述斜 面套的下端面为平面， 上端面为曲面， 该曲面有一最高点和最低点。
5、根据权利要求 2所述的三维运动式旋混装置， 其特征在于， 所述轴 承组件包括轴承套、 万向轴承座及万向轴承， 其中轴承套与斜面套连接， 万向轴承座装在轴承套内， 万向轴承则装在万向轴承座内。
6、根据权利要求 1所述的三维运动式旋混装置， 其特征在于， 所述容 器固定机构是由托盘和固定座构成， 其中托盘分别与驱动机构及柔性连接 件连接； 固定座由至少两个固定片和与之连成一体的强磁铁块构成， 它们 可设置于托盘上的任意部位， 以卡固不同大小的容器。
7、根据权利要求 6所述的三维运动式旋混装置， 其特征在于， 所述固 定片为角形或弧面形并向内弯曲， 强磁铁块固定于固定片底部， 并通过磁 力吸附于托盘上， 其位置可任意调整。
8、根据权利要求 1所述的三维运动式旋混装置， 其特征在于， 所述柔 性连接件为橡胶波紋管。
替换页（细则第 26条)
PCT/CN2002/000357 2001-06-04 2002-05-28 Dispositif de melange rotatif de type mouvement a trois dimensions WO2002098548A1 (fr)

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